Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Slc16a1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SLC16A1
- Mouse genes Slc16a1
- Rat genes Slc16a1
- Zfish genes slc16a1a,slc16a1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc16a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046943	carboxylic acid transmembrane transporter activity	Slc16a1	IMP		Rat	PMID:10714609\|RGD:30309914
Molecular Function	GO:0042802	identical protein binding	Slc16a1	IPI	RGD:3690	Rat	PMID:19473976\|RGD:7242735
Molecular Function	GO:0015129	lactate transmembrane transporter activity	Slc16a1	IMP		Mouse	PMID:29026134
Molecular Function	GO:0015650	lactate:proton symporter activity	SLC16A1	IDA		Human	PMID:12946269
Molecular Function	GO:0015650	lactate:proton symporter activity	Slc16a1	IDA		Rat	PMID:9639576\|RGD:155230795
Molecular Function	GO:0008028	monocarboxylic acid transmembrane transporter activity	SLC16A1	IDA		Human	PMID:25371203
Molecular Function	GO:0008028	monocarboxylic acid transmembrane transporter activity	Slc16a1	IDA		Rat	PMID:8526936\|RGD:729907
Molecular Function	GO:0097159	organic cyclic compound binding	Slc16a1	IMP		Rat	PMID:19473976\|RGD:7242735
Molecular Function	GO:0097159	organic cyclic compound binding	Slc16a1	IPI	CHEBI:4286	Rat	PMID:19473976\|RGD:7242735
Molecular Function	GO:0005515	protein binding	SLC16A1	IPI	UniProtKB:P26453	Human	PMID:10921872
Molecular Function	GO:0005515	protein binding	Slc16a1	IPI	UniProtKB:P18572	Mouse	MGI:MGI:7310007\|PMID:21792931
Molecular Function	GO:0005515	protein binding	Slc16a1	IPI	UniProtKB:P26453	Rat	PMID:11719518\|RGD:8554052
Molecular Function	GO:0005515	protein binding	Slc16a1	IPI	RGD:2220	Rat	PMID:16434551\|RGD:2289062
Molecular Function	GO:0005515	protein binding	Slc16a1	IPI	UniProtKB:P35613	Rat	PMID:17127621\|RGD:8554372
Molecular Function	GO:0015295	solute:proton symporter activity	Slc16a1	IDA		Rat	PMID:9374487\|RGD:155230711
Molecular Function	GO:0015141	succinate transmembrane transporter activity	SLC16A1	IDA		Human	PMID:32946811
Cellular Component	GO:0016324	apical plasma membrane	SLC16A1	IDA		Human	PMID:15901598
Cellular Component	GO:0016324	apical plasma membrane	SLC16A1	IDA		Human	PMID:26854723
Cellular Component	GO:0016324	apical plasma membrane	SLC16A1	IDA		Human	PMID:31678436
Cellular Component	GO:0016324	apical plasma membrane	SLC16A1	IDA		Human	PMID:31791063
Cellular Component	GO:0016324	apical plasma membrane	Slc16a1	IDA		Rat	PMID:18619525\|RGD:2301072
Cellular Component	GO:0009925	basal plasma membrane	SLC16A1	IDA		Human	PMID:26854723
Cellular Component	GO:0016323	basolateral plasma membrane	Slc16a1	IDA		Rat	PMID:10564700\|RGD:153298937
Cellular Component	GO:0016323	basolateral plasma membrane	Slc16a1	IDA		Rat	PMID:18619525\|RGD:2301072
Cellular Component	GO:0030054	cell junction	SLC16A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005813	centrosome	SLC16A1	IDA		Human	PMID:23816619
Cellular Component	GO:0070062	extracellular exosome	SLC16A1	HDA		Human	PMID:20458337
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	SLC16A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016328	lateral plasma membrane	SLC16A1	IDA		Human	PMID:26854723
Cellular Component	GO:0016020	membrane	SLC16A1	HDA		Human	PMID:19946888
Cellular Component	GO:0005739	mitochondrion	Slc16a1	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005886	plasma membrane	SLC16A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	SLC16A1	IDA		Human	PMID:15505343
Cellular Component	GO:0005886	plasma membrane	SLC16A1	IDA		Human	PMID:24390345
Cellular Component	GO:0005886	plasma membrane	SLC16A1	IDA		Human	PMID:25957687
Cellular Component	GO:0005886	plasma membrane	SLC16A1	IDA		Human	PMID:23137377
Cellular Component	GO:0005886	plasma membrane	SLC16A1	IDA		Human	PMID:25371203
Cellular Component	GO:0005886	plasma membrane	SLC16A1	IDA		Human	PMID:28112518
Cellular Component	GO:0005886	plasma membrane	Slc16a1	IDA		Mouse	MGI:MGI:7310007\|PMID:21792931
Cellular Component	GO:0005886	plasma membrane	Slc16a1	IDA		Mouse	PMID:15037112
Cellular Component	GO:0005886	plasma membrane	Slc16a1	IDA		Mouse	PMID:31837519
Cellular Component	GO:0005886	plasma membrane	Slc16a1	IDA		Mouse	PMID:29026134
Cellular Component	GO:0005886	plasma membrane	Slc16a1	IDA		Rat	PMID:11719518\|RGD:8554052
Cellular Component	GO:0005886	plasma membrane	Slc16a1	IDA		Rat	PMID:17127621\|RGD:8554372
Cellular Component	GO:0005886	plasma membrane	Slc16a1	IDA		Rat	PMID:19473976\|RGD:7242735
Cellular Component	GO:0005886	plasma membrane	Slc16a1	IDA		Rat	PMID:19929853\|RGD:7327222
Cellular Component	GO:0045202	synapse	Slc16a1	EXP		Mouse	PMID:15572359
Cellular Component	GO:0045202	synapse	Slc16a1	IDA		Mouse	PMID:15572359
Biological Process	GO:0051780	behavioral response to nutrient	Slc16a1	IMP		Mouse	MGI:MGI:5545659\|PMID:24367518
Biological Process	GO:1905039	carboxylic acid transmembrane transport	Slc16a1	IMP		Rat	PMID:10714609\|RGD:30309914
Biological Process	GO:0071407	cellular response to organic cyclic compound	Slc16a1	IEP		Rat	PMID:19473976\|RGD:7242735
Biological Process	GO:0071407	cellular response to organic cyclic compound	Slc16a1	IMP		Rat	PMID:19473976\|RGD:7242735
Biological Process	GO:0007098	centrosome cycle	SLC16A1	IMP		Human	PMID:23816619
Biological Process	GO:0042593	glucose homeostasis	Slc16a1	IMP		Mouse	MGI:MGI:5465432\|PMID:22522610
Biological Process	GO:0035873	lactate transmembrane transport	Slc16a1	IDA		Rat	PMID:19473976\|RGD:7242735
Biological Process	GO:0035873	lactate transmembrane transport	Slc16a1	IMP		Rat	PMID:19473976\|RGD:7242735
Biological Process	GO:0006629	lipid metabolic process	Slc16a1	IMP		Mouse	MGI:MGI:5545659\|PMID:24367518
Biological Process	GO:0015718	monocarboxylic acid transport	SLC16A1	IDA		Human	PMID:25371203
Biological Process	GO:0015718	monocarboxylic acid transport	Slc16a1	IDA		Rat	PMID:8526936\|RGD:729907
Biological Process	GO:0035879	plasma membrane lactate transport	Slc16a1	IMP		Mouse	MGI:MGI:6109451\|PMID:29026134
Biological Process	GO:0035879	plasma membrane lactate transport	Slc16a1	IMP		Rat	PMID:17127621\|RGD:8554372
Biological Process	GO:0035879	plasma membrane lactate transport	Slc16a1	IDA		Rat	PMID:19929853\|RGD:7327222
Biological Process	GO:0042867	pyruvate catabolic process	Slc16a1	IMP		Mouse	PMID:29026134
Biological Process	GO:1901475	pyruvate transmembrane transport	Slc16a1	IDA		Rat	PMID:9639576\|RGD:155230795
Biological Process	GO:0050796	regulation of insulin secretion	Slc16a1	IMP		Mouse	MGI:MGI:5465432\|PMID:22522610
Biological Process	GO:0032094	response to food	Slc16a1	IMP		Mouse	MGI:MGI:5545659\|PMID:24367518
Biological Process	GO:0071422	succinate transmembrane transport	SLC16A1	IDA		Human	PMID:32946811

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.