Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC16A2
  • Mouse genes Slc16a2
  • Rat genes Slc16a2
  • Zfish genes slc16a2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc16a2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015171	amino acid transmembrane transporter activity	SLC16A2	IDA		Human	PMID:26305885
Molecular Function	GO:0042802	identical protein binding	SLC16A2	IDA		Human	PMID:19797118
Molecular Function	GO:0070324	thyroid hormone binding	slc16a2	IDA		Zfish	PMID:21952246
Molecular Function	GO:0015349	thyroid hormone transmembrane transporter activity	SLC16A2	IDA		Human	PMID:19022891
Molecular Function	GO:0015349	thyroid hormone transmembrane transporter activity	SLC16A2	IDA		Human	PMID:21315799
Molecular Function	GO:0015349	thyroid hormone transmembrane transporter activity	SLC16A2	IDA		Human	PMID:26305885
Molecular Function	GO:0015349	thyroid hormone transmembrane transporter activity	SLC16A2	IMP		Human	PMID:26426690
Molecular Function	GO:0015349	thyroid hormone transmembrane transporter activity	SLC16A2	IMP		Human	PMID:28526555
Molecular Function	GO:0015349	thyroid hormone transmembrane transporter activity	Slc16a2	IDA		Mouse	MGI:MGI:7310188|PMID:31436139
Molecular Function	GO:0015349	thyroid hormone transmembrane transporter activity	Slc16a2	IMP		Rat	PMID:12871948|RGD:1304408
Molecular Function	GO:0015349	thyroid hormone transmembrane transporter activity	slc16a2	IDA		Zfish	PMID:31436139
Cellular Component	GO:0016324	apical plasma membrane	SLC16A2	IDA		Human	PMID:18687783
Cellular Component	GO:0016324	apical plasma membrane	Slc16a2	IDA		Mouse	MGI:MGI:6383361|PMID:18687783
Cellular Component	GO:0016324	apical plasma membrane	Slc16a2	IDA		Rat	PMID:18687783|RGD:15090845
Cellular Component	GO:0005886	plasma membrane	SLC16A2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	SLC16A2	IDA		Human	PMID:26426690
Cellular Component	GO:0005886	plasma membrane	SLC16A2	IDA		Human	PMID:19022891
Cellular Component	GO:0005886	plasma membrane	SLC16A2	IDA		Human	PMID:21315799
Cellular Component	GO:0005886	plasma membrane	Slc16a2	IDA		Rat	PMID:18687783|RGD:15090845
Biological Process	GO:0089718	amino acid import across plasma membrane	SLC16A2	IDA		Human	PMID:26305885
Biological Process	GO:0006520	amino acid metabolic process	SLC16A2	IGI	UniProtKB:P49895	Human	PMID:26305885
Biological Process	GO:0007420	brain development	slc16a2	IMP	ZFIN:ZDB-MRPHLNO-140925-1	Zfish	PMID:24877564
Biological Process	GO:0007420	brain development	slc16a2	IMP	ZFIN:ZDB-MRPHLNO-140707-4	Zfish	PMID:24693966
Biological Process	GO:0007417	central nervous system development	slc16a2	IMP	ZFIN:ZDB-MRPHLNO-130409-1	Zfish	PMID:23161551
Biological Process	GO:0043009	chordate embryonic development	slc16a2	IMP	ZFIN:ZDB-MRPHLNO-130409-2	Zfish	PMID:23161551
Biological Process	GO:0043009	chordate embryonic development	slc16a2	IMP	ZFIN:ZDB-MRPHLNO-130409-1	Zfish	PMID:23161551
Biological Process	GO:0009914	hormone transport	Slc16a2	IMP		Rat	PMID:12871948|RGD:1304408
Biological Process	GO:0040011	locomotion	slc16a2	IMP	ZFIN:ZDB-MRPHLNO-140707-4	Zfish	PMID:24693966
Biological Process	GO:2000178	negative regulation of neural precursor cell proliferation	SLC16A2	IMP		Human	PMID:19022891
Biological Process	GO:0030182	neuron differentiation	slc16a2	IMP	ZFIN:ZDB-MRPHLNO-140925-1	Zfish	PMID:24877564
Biological Process	GO:0048709	oligodendrocyte differentiation	slc16a2	IMP	ZFIN:ZDB-GENO-150122-1	Zfish	PMID:27664134
Biological Process	GO:0071632	optomotor response	slc16a2	IMP	ZFIN:ZDB-GENO-221110-5	Zfish	PMID:35269606
Biological Process	GO:0014037	Schwann cell differentiation	slc16a2	IMP	ZFIN:ZDB-GENO-150122-1	Zfish	PMID:27664134
Biological Process	GO:0021510	spinal cord development	slc16a2	IMP	ZFIN:ZDB-MRPHLNO-140925-1	Zfish	PMID:24877564
Biological Process	GO:0021529	spinal cord oligodendrocyte cell differentiation	slc16a2	IMP	ZFIN:ZDB-GENO-150122-1	Zfish	PMID:27664134
Biological Process	GO:0030878	thyroid gland development	slc16a2	IMP	ZFIN:ZDB-MRPHLNO-140707-4	Zfish	PMID:24693966
Biological Process	GO:0006590	thyroid hormone generation	Slc16a2	IMP	MGI:MGI:3710233	Mouse	PMID:24248460
Biological Process	GO:0006590	thyroid hormone generation	Slc16a2	IGI	MGI:MGI:1919722	Mouse	PMID:24248460
Biological Process	GO:0042403	thyroid hormone metabolic process	SLC16A2	IGI	UniProtKB:P55073	Human	PMID:26305885
Biological Process	GO:0070327	thyroid hormone transport	SLC16A2	IDA		Human	PMID:19022891
Biological Process	GO:0070327	thyroid hormone transport	SLC16A2	IDA		Human	PMID:21315799
Biological Process	GO:0070327	thyroid hormone transport	SLC16A2	IDA		Human	PMID:26305885
Biological Process	GO:0070327	thyroid hormone transport	SLC16A2	IMP		Human	PMID:26426690
Biological Process	GO:0070327	thyroid hormone transport	SLC16A2	IMP		Human	PMID:28526555
Biological Process	GO:0070327	thyroid hormone transport	Slc16a2	IDA		Mouse	MGI:MGI:7310188|PMID:31436139
Biological Process	GO:0070327	thyroid hormone transport	Slc16a2	IMP	MGI:MGI:3710233	Mouse	PMID:24248460
Biological Process	GO:0070327	thyroid hormone transport	Slc16a2	IGI	MGI:MGI:1919722	Mouse	PMID:24248460
Biological Process	GO:0070460	thyroid-stimulating hormone secretion	Slc16a2	IGI	MGI:MGI:1919722	Mouse	PMID:24248460
Biological Process	GO:0070460	thyroid-stimulating hormone secretion	Slc16a2	IMP	MGI:MGI:3710233	Mouse	PMID:24248460
Biological Process	GO:0019226	transmission of nerve impulse	slc16a2	IMP	ZFIN:ZDB-GENO-221110-10	Zfish	PMID:35269606
Biological Process	GO:0150104	transport across blood-brain barrier	SLC16A2	IMP		Human	PMID:28526555

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern