Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Slc17a7

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SLC17A7
- Mouse genes Slc17a7
- Rat genes Slc17a7
- Zfish genes slc17a7a,slc17a7b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc17a7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005254	chloride channel activity	Slc17a7	IDA		Mouse	MGI:MGI:6838939\|PMID:25433636
Molecular Function	GO:0005254	chloride channel activity	Slc17a7	IDA		Mouse	MGI:MGI:6112211\|PMID:29273736
Molecular Function	GO:0005254	chloride channel activity	Slc17a7	IDA		Rat	PMID:10938000\|RGD:12050146
Molecular Function	GO:0005254	chloride channel activity	Slc17a7	IDA		Rat	PMID:19169251\|RGD:152025512
Molecular Function	GO:0008068	extracellularly glutamate-gated chloride channel activity	Slc17a7	IDA		Mouse	PMID:19169251
Molecular Function	GO:0005315	inorganic phosphate transmembrane transporter activity	Slc17a7	IDA		Rat	PMID:8202535\|RGD:633922
Molecular Function	GO:0005313	L-glutamate transmembrane transporter activity	Slc17a7	IDA		Rat	PMID:19169251\|RGD:152025512
Molecular Function	GO:0140788	L-glutamate uniporter activity	Slc17a7	IDA		Mouse	MGI:MGI:7275317\|PMID:29642010
Molecular Function	GO:0140788	L-glutamate uniporter activity	Slc17a7	IDA		Mouse	MGI:MGI:6838939\|PMID:25433636
Molecular Function	GO:0140788	L-glutamate uniporter activity	Slc17a7	IDA		Rat	PMID:10938000\|RGD:12050146
Molecular Function	GO:0140788	L-glutamate uniporter activity	Slc17a7	IDA		Rat	PMID:18080752\|RGD:152025516
Molecular Function	GO:0140788	L-glutamate uniporter activity	Slc17a7	IDA		Rat	PMID:29642010\|RGD:152025529
Molecular Function	GO:0140787	phosphate ion uniporter activity	Slc17a7	IDA		Mouse	MGI:MGI:7275317\|PMID:29642010
Molecular Function	GO:0140787	phosphate ion uniporter activity	Slc17a7	IDA		Rat	PMID:29642010\|RGD:152025529
Molecular Function	GO:0015386	potassium:proton antiporter activity	Slc17a7	IDA		Rat	PMID:25433636\|RGD:152025511
Molecular Function	GO:0005515	protein binding	Slc17a7	IPI	RGD:620276	Rat	PMID:16815333\|RGD:13504741
Molecular Function	GO:0005515	protein binding	Slc17a7	IPI	RGD:620578	Rat	PMID:16815333\|RGD:13504741
Molecular Function	GO:0005515	protein binding	Slc17a7	IPI	RGD:708456	Rat	PMID:16815333\|RGD:13504741
Molecular Function	GO:0015319	sodium:inorganic phosphate symporter activity	SLC17A7	IDA		Human	PMID:10820226
Molecular Function	GO:0005436	sodium:phosphate symporter activity	Slc17a7	IDA		Mouse	MGI:MGI:6716135\|PMID:33440152
Molecular Function	GO:0005436	sodium:phosphate symporter activity	Slc17a7	IDA		Mouse	MGI:MGI:7275317\|PMID:29642010
Molecular Function	GO:0005436	sodium:phosphate symporter activity	Slc17a7	IDA		Rat	PMID:29642010\|RGD:152025529
Molecular Function	GO:0005436	sodium:phosphate symporter activity	Slc17a7	IDA		Rat	PMID:8202535\|RGD:633922
Cellular Component	GO:0044300	cerebellar mossy fiber	Slc17a7	IDA		Mouse	PMID:23791195
Cellular Component	GO:0060076	excitatory synapse	Slc17a7	IDA		Mouse	PMID:16980967
Cellular Component	GO:0060076	excitatory synapse	Slc17a7	IDA		Mouse	PMID:17823315
Cellular Component	GO:0060076	excitatory synapse	Slc17a7	IDA		Mouse	PMID:21356198
Cellular Component	GO:0060076	excitatory synapse	Slc17a7	IDA		Rat	PMID:16519671\|RGD:9999155
Cellular Component	GO:0060076	excitatory synapse	Slc17a7	IDA		Rat	PMID:19730411\|RGD:8554379
Cellular Component	GO:0060076	excitatory synapse	Slc17a7	IDA		Rat	PMID:19914352\|RGD:8554031
Cellular Component	GO:0043229	intracellular organelle	Slc17a7	IDA		Rat	PMID:17600303\|RGD:6480260
Cellular Component	GO:0016020	membrane	SLC17A7	IDA		Human	PMID:10820226
Cellular Component	GO:0016020	membrane	Slc17a7	IDA		Rat	PMID:8202535\|RGD:633922
Cellular Component	GO:0048786	presynaptic active zone	Slc17a7	IDA		Mouse	MGI:MGI:4820709\|PMID:18986540
Cellular Component	GO:0048786	presynaptic active zone	Slc17a7	IDA		Rat	PMID:24613359\|RGD:10047247
Cellular Component	GO:0045202	synapse	Slc17a7	IDA		Mouse	PMID:16814779
Cellular Component	GO:0045202	synapse	Slc17a7	IDA		Mouse	PMID:15118123
Cellular Component	GO:0045202	synapse	Slc17a7	IDA		Rat	PMID:15681343\|RGD:8553420
Cellular Component	GO:0008021	synaptic vesicle	Slc17a7	IDA		Mouse	PMID:21378974
Cellular Component	GO:0008021	synaptic vesicle	Slc17a7	IDA		Mouse	PMID:15579147
Cellular Component	GO:0030672	synaptic vesicle membrane	Slc17a7	IDA		Mouse	PMID:15860731
Cellular Component	GO:0030672	synaptic vesicle membrane	Slc17a7	IDA		Rat	PMID:18502731\|RGD:9999204
Cellular Component	GO:0030672	synaptic vesicle membrane	Slc17a7	IDA		Rat	PMID:29642010\|RGD:152025529
Biological Process	GO:0007420	brain development	Slc17a7	IEP		Rat	PMID:15515175\|RGD:9999149
Biological Process	GO:0007268	chemical synaptic transmission	Slc17a7	IMP	MGI:MGI:3617803	Mouse	PMID:17611277
Biological Process	GO:0006821	chloride transport	Slc17a7	IDA		Rat	PMID:10938000\|RGD:12050146
Biological Process	GO:0051649	establishment of localization in cell	Slc17a7	IMP	MGI:MGI:3617803	Mouse	PMID:15118123
Biological Process	GO:0060079	excitatory postsynaptic potential	Slc17a7	IMP	MGI:MGI:3617803	Mouse	PMID:15118123
Biological Process	GO:0051938	L-glutamate import	Slc17a7	IGI	MGI:MGI:1345280	Mouse	PMID:15860731
Biological Process	GO:0051938	L-glutamate import	Slc17a7	IDA		Mouse	PMID:15860731
Biological Process	GO:0051938	L-glutamate import	Slc17a7	IMP	MGI:MGI:3617803	Mouse	PMID:15118123
Biological Process	GO:0015813	L-glutamate transmembrane transport	Slc17a7	IDA		Mouse	MGI:MGI:6838939\|PMID:25433636
Biological Process	GO:0015813	L-glutamate transmembrane transport	Slc17a7	IDA		Mouse	MGI:MGI:7275317\|PMID:29642010
Biological Process	GO:0015813	L-glutamate transmembrane transport	Slc17a7	IDA		Rat	PMID:10938000\|RGD:12050146
Biological Process	GO:0015813	L-glutamate transmembrane transport	Slc17a7	IDA		Rat	PMID:18080752\|RGD:152025516
Biological Process	GO:0015813	L-glutamate transmembrane transport	Slc17a7	IDA		Rat	PMID:19169251\|RGD:152025512
Biological Process	GO:0015813	L-glutamate transmembrane transport	Slc17a7	IDA		Rat	PMID:29642010\|RGD:152025529
Biological Process	GO:0007616	long-term memory	Slc17a7	IMP	MGI:MGI:3051945	Mouse	PMID:17241289
Biological Process	GO:0051651	maintenance of location in cell	Slc17a7	IMP	MGI:MGI:3051945	Mouse	PMID:15103023
Biological Process	GO:0003407	neural retina development	Slc17a7	IEP		Rat	PMID:18482716\|RGD:9999162
Biological Process	GO:0098700	neurotransmitter loading into synaptic vesicle	Slc17a7	IMP		Mouse	PMID:15118123
Biological Process	GO:0098700	neurotransmitter loading into synaptic vesicle	Slc17a7	IDA		Mouse	PMID:15118123
Biological Process	GO:0098700	neurotransmitter loading into synaptic vesicle	Slc17a7	IDA		Rat	PMID:10938000\|RGD:12050146
Biological Process	GO:0055062	phosphate ion homeostasis	Slc17a7	IDA		Mouse	MGI:MGI:6716135\|PMID:33440152
Biological Process	GO:0055062	phosphate ion homeostasis	Slc17a7	IDA		Rat	PMID:33440152\|RGD:152025514
Biological Process	GO:0035435	phosphate ion transmembrane transport	Slc17a7	IDA		Mouse	MGI:MGI:7275317\|PMID:29642010
Biological Process	GO:0006817	phosphate ion transport	Slc17a7	IDA		Mouse	MGI:MGI:7275317\|PMID:29642010
Biological Process	GO:0006817	phosphate ion transport	Slc17a7	IDA		Rat	PMID:29642010\|RGD:152025529
Biological Process	GO:0006817	phosphate ion transport	Slc17a7	IDA		Rat	PMID:8202535\|RGD:633922
Biological Process	GO:0006813	potassium ion transport	Slc17a7	IDA		Rat	PMID:25433636\|RGD:152025511
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	Slc17a7	IMP		Rat	PMID:16815333\|RGD:13504741
Biological Process	GO:0042137	sequestering of neurotransmitter	Slc17a7	IMP	MGI:MGI:3051945	Mouse	PMID:15103023
Biological Process	GO:0044341	sodium-dependent phosphate transport	Slc17a7	IDA		Mouse	MGI:MGI:6716135\|PMID:33440152
Biological Process	GO:0044341	sodium-dependent phosphate transport	Slc17a7	IDA		Mouse	MGI:MGI:7275317\|PMID:29642010
Biological Process	GO:0044341	sodium-dependent phosphate transport	Slc17a7	IDA		Rat	PMID:29642010\|RGD:152025529
Biological Process	GO:0035249	synaptic transmission, glutamatergic	Slc17a7	IMP	MGI:MGI:3617803	Mouse	PMID:15118123
Biological Process	GO:0097401	synaptic vesicle lumen acidification	Slc17a7	IMP	MGI:MGI:3051945	Mouse	PMID:19169251

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.