Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Slc19a1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SLC19A1
- Mouse genes Slc19a1
- Rat genes Slc19a1
- Zfish genes slc19a1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc19a1

Category	ID	Classification term	Gene	Evidence	Organism	Reference
Molecular Function	GO:0061507	2',3'-cyclic GMP-AMP binding	SLC19A1	IDA	Human	PMID:31126740
Molecular Function	GO:0061507	2',3'-cyclic GMP-AMP binding	SLC19A1	IDA	Human	PMID:31511694
Molecular Function	GO:0015297	antiporter activity	SLC19A1	IDA	Human	PMID:22554803
Molecular Function	GO:0140360	cyclic-GMP-AMP transmembrane transporter activity	SLC19A1	IDA	Human	PMID:31126740
Molecular Function	GO:0140360	cyclic-GMP-AMP transmembrane transporter activity	SLC19A1	IDA	Human	PMID:31511694
Molecular Function	GO:0008518	folate:monoatomic anion antiporter activity	SLC19A1	IDA	Human	PMID:14609557
Molecular Function	GO:0008518	folate:monoatomic anion antiporter activity	SLC19A1	IDA	Human	PMID:22554803
Molecular Function	GO:0008518	folate:monoatomic anion antiporter activity	SLC19A1	IMP	Human	PMID:28885847
Molecular Function	GO:0008518	folate:monoatomic anion antiporter activity	Slc19a1	IDA	Rat	PMID:11600421\|RGD:735239
Molecular Function	GO:0005542	folic acid binding	Slc19a1	IDA	Rat	PMID:11600421\|RGD:735239
Molecular Function	GO:0008517	folic acid transmembrane transporter activity	Slc19a1	IDA	Mouse	MGI:MGI:87123\|PMID:9111015
Molecular Function	GO:0008517	folic acid transmembrane transporter activity	Slc19a1	IDA	Mouse	MGI:MGI:1303207\|PMID:9748272
Molecular Function	GO:0008517	folic acid transmembrane transporter activity	Slc19a1	IDA	Rat	PMID:19243012\|RGD:7244267
Molecular Function	GO:0008517	folic acid transmembrane transporter activity	Slc19a1	IDA	Rat	PMID:23287122\|RGD:7244264
Molecular Function	GO:0015350	methotrexate transmembrane transporter activity	SLC19A1	IDA	Human	PMID:22554803
Molecular Function	GO:0015350	methotrexate transmembrane transporter activity	Slc19a1	IDA	Mouse	MGI:MGI:1303207\|PMID:9748272
Molecular Function	GO:0015350	methotrexate transmembrane transporter activity	Slc19a1	IDA	Rat	PMID:10827155\|RGD:14929207
Molecular Function	GO:0008514	organic anion transmembrane transporter activity	Slc19a1	IMP	Rat	PMID:18762716\|RGD:30309935
Molecular Function	GO:0042910	xenobiotic transmembrane transporter activity	Slc19a1	IMP	Rat	PMID:21737571\|RGD:25671393
Cellular Component	GO:0016324	apical plasma membrane	SLC19A1	IDA	Human	PMID:10787414
Cellular Component	GO:0016324	apical plasma membrane	SLC19A1	IDA	Human	PMID:31791063
Cellular Component	GO:0016324	apical plasma membrane	Slc19a1	IDA	Mouse	MGI:MGI:5645212\|PMID:10787414
Cellular Component	GO:0016324	apical plasma membrane	Slc19a1	IDA	Rat	PMID:21556118\|RGD:25671401
Cellular Component	GO:0016324	apical plasma membrane	Slc19a1	IDA	Rat	PMID:21737571\|RGD:25671393
Cellular Component	GO:0016323	basolateral plasma membrane	SLC19A1	IDA	Human	PMID:10787414
Cellular Component	GO:0016323	basolateral plasma membrane	SLC19A1	IDA	Human	PMID:31791063
Cellular Component	GO:0016323	basolateral plasma membrane	Slc19a1	IDA	Rat	PMID:15846510\|RGD:2315833
Cellular Component	GO:0016323	basolateral plasma membrane	Slc19a1	IDA	Rat	PMID:19243012\|RGD:7244267
Cellular Component	GO:0016323	basolateral plasma membrane	Slc19a1	IDA	Rat	PMID:21556118\|RGD:25671401
Cellular Component	GO:0031526	brush border membrane	Slc19a1	IDA	Rat	PMID:23287122\|RGD:7244264
Cellular Component	GO:0005886	plasma membrane	SLC19A1	IDA	Human	PMID:23137377
Cellular Component	GO:0005886	plasma membrane	SLC19A1	IDA	Human	PMID:28112518
Cellular Component	GO:0005886	plasma membrane	Slc19a1	IDA	Rat	PMID:14612385\|RGD:1304457
Biological Process	GO:0140361	cyclic-GMP-AMP transmembrane import across plasma membrane	SLC19A1	IDA	Human	PMID:31126740
Biological Process	GO:0140361	cyclic-GMP-AMP transmembrane import across plasma membrane	SLC19A1	IDA	Human	PMID:31511694
Biological Process	GO:0007565	female pregnancy	Slc19a1	IEP	Rat	PMID:18776693\|RGD:2315832
Biological Process	GO:1904447	folate import across plasma membrane	SLC19A1	IDA	Human	PMID:14609557
Biological Process	GO:1904447	folate import across plasma membrane	SLC19A1	IDA	Human	PMID:22554803
Biological Process	GO:1904447	folate import across plasma membrane	Slc19a1	IDA	Mouse	MGI:MGI:87123\|PMID:9111015
Biological Process	GO:1904447	folate import across plasma membrane	Slc19a1	IDA	Mouse	MGI:MGI:1303207\|PMID:9748272
Biological Process	GO:0098838	folate transmembrane transport	SLC19A1	IDA	Human	PMID:22554803
Biological Process	GO:0098838	folate transmembrane transport	Slc19a1	IDA	Mouse	MGI:MGI:87123\|PMID:9111015
Biological Process	GO:0098838	folate transmembrane transport	Slc19a1	IDA	Mouse	MGI:MGI:1303207\|PMID:9748272
Biological Process	GO:0015884	folic acid transport	SLC19A1	IMP	Human	PMID:28885847
Biological Process	GO:0015884	folic acid transport	Slc19a1	IDA	Rat	PMID:11600421\|RGD:735239
Biological Process	GO:0015884	folic acid transport	Slc19a1	IDA	Rat	PMID:19243012\|RGD:7244267
Biological Process	GO:0015884	folic acid transport	Slc19a1	IDA	Rat	PMID:23287122\|RGD:7244264
Biological Process	GO:0051958	methotrexate transport	SLC19A1	IDA	Human	PMID:22554803
Biological Process	GO:0051958	methotrexate transport	Slc19a1	IDA	Mouse	MGI:MGI:1303207\|PMID:9748272
Biological Process	GO:0051958	methotrexate transport	Slc19a1	IDA	Rat	PMID:10827155\|RGD:14929207
Biological Process	GO:0015711	organic anion transport	Slc19a1	IMP	Rat	PMID:18762716\|RGD:30309935
Biological Process	GO:0006855	xenobiotic transmembrane transport	Slc19a1	IMP	Rat	PMID:21737571\|RGD:25671393

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/24/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.