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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Slc1a1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc1a1
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0015108chloride transmembrane transporter activitySLC1A1IMPHumanPMID:8857541
Molecular FunctionGO:0033229cysteine transmembrane transporter activitySLC1A1IDAHumanPMID:21123949
Molecular FunctionGO:0033229cysteine transmembrane transporter activitySlc1a1IDAMouseMGI:MGI:6304522|PMID:30840898
Molecular FunctionGO:0033229cysteine transmembrane transporter activitySlc1a1IDAMousePMID:12614333
Molecular FunctionGO:0140010D-aspartate transmembrane transporter activitySLC1A1IDAHumanPMID:7914198
Molecular FunctionGO:0016595glutamate bindingSlc1a1IDARatPMID:16128593|RGD:1599319
Molecular FunctionGO:0015501glutamate:sodium symporter activitySLC1A1IDAHumanPMID:8857541
Molecular FunctionGO:0015501glutamate:sodium symporter activitySlc1a1IDAMousePMID:12119102
Molecular FunctionGO:0015501glutamate:sodium symporter activitySlc1a1IDARatPMID:16128593|RGD:1599319
Molecular FunctionGO:0005314high-affinity L-glutamate transmembrane transporter activitySLC1A1IDAHumanPMID:26690923
Molecular FunctionGO:0005314high-affinity L-glutamate transmembrane transporter activitySLC1A1IDAHumanPMID:8857541
Molecular FunctionGO:0042802identical protein bindingSlc1a1IPIPR:P51906MousePMID:15009636
Molecular FunctionGO:0042802identical protein bindingSlc1a1IPIRGD:3696RatPMID:16128593|RGD:1599319
Molecular FunctionGO:0015183L-aspartate transmembrane transporter activitySLC1A1IDAHumanPMID:7914198
Molecular FunctionGO:0005313L-glutamate transmembrane transporter activitySLC1A1IDAHumanPMID:12562531
Molecular FunctionGO:0005313L-glutamate transmembrane transporter activitySLC1A1IDAHumanPMID:21123949
Molecular FunctionGO:0005313L-glutamate transmembrane transporter activitySLC1A1IDAHumanPMID:7521911
Molecular FunctionGO:0005313L-glutamate transmembrane transporter activitySLC1A1IDAHumanPMID:7914198
Molecular FunctionGO:0005313L-glutamate transmembrane transporter activitySlc1a1IMPMGI:MGI:2655190MousePMID:14715943
Molecular FunctionGO:0005313L-glutamate transmembrane transporter activitySlc1a1IDAMousePMID:11030592
Molecular FunctionGO:0005313L-glutamate transmembrane transporter activitySlc1a1IDAMousePMID:15471567
Molecular FunctionGO:0005313L-glutamate transmembrane transporter activitySlc1a1IDAMousePMID:15009636
Molecular FunctionGO:0005313L-glutamate transmembrane transporter activitySlc1a1IDARatPMID:16128593|RGD:1599319
Molecular FunctionGO:0005253monoatomic anion channel activitySlc1a1IDAMousePMID:15471567
Molecular FunctionGO:0005515protein bindingSLC1A1IPIUniProtKB:Q5T700HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSLC1A1IPIUniProtKB:Q99942HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSLC1A1IPIUniProtKB:Q5T700HumanPMID:31515488
Molecular FunctionGO:0005515protein bindingSLC1A1IPIUniProtKB:O75459HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSLC1A1IPIUniProtKB:P78382HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSLC1A1IPIUniProtKB:Q14802-3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSLC1A1IPIUniProtKB:Q5JX71HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSLC1A1IPIUniProtKB:Q7Z7N9HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSLC1A1IPIUniProtKB:Q8TBG9HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSLC1A1IPIUniProtKB:Q99942HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSLC1A1IPIUniProtKB:Q9Y282HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSlc1a1IPIUniProtKB:Q9EPR5MouseMGI:MGI:6304522|PMID:30840898
Molecular FunctionGO:0005515protein bindingSlc1a1IPIUniProtKB:Q8R5J9MouseMGI:MGI:3822963|PMID:18684713
Molecular FunctionGO:0005515protein bindingSlc1a1IPIUniProtKB:Q9QZS3MousePMID:27358480
Molecular FunctionGO:0005515protein bindingSlc1a1IPIUniProtKB:P49817MousePMID:17715130
Molecular FunctionGO:0005515protein bindingSlc1a1IPIUniProtKB:Q9WVC3MousePMID:17715130
Molecular FunctionGO:0005515protein bindingSlc1a1IPIUniProtKB:P53702MousePMID:16858406
Molecular FunctionGO:0005515protein bindingSlc1a1IPIUniProtKB:Q8R5J9MousePMID:18799673
Molecular FunctionGO:0005515protein bindingSlc1a1IPIRGD:3395RatPMID:16045453|RGD:1601476
Molecular FunctionGO:0005515protein bindingSlc1a1IPIUniProtKB:Q6WN19RatPMID:18096700|RGD:40902968
Cellular ComponentGO:0097440apical dendriteSlc1a1IDARatPMID:10701825|RGD:21201260
Cellular ComponentGO:0016324apical plasma membraneSLC1A1IDAHumanPMID:21123949
Cellular ComponentGO:0016324apical plasma membraneSlc1a1IDAMousePMID:26739563
Cellular ComponentGO:0032279asymmetric synapseSlc1a1IDARatPMID:10701825|RGD:21201260
Cellular ComponentGO:0032279asymmetric synapseSlc1a1IDARatPMID:9542890|RGD:21201279
Cellular ComponentGO:0030424axonSlc1a1IDARatPMID:10701825|RGD:21201260
Cellular ComponentGO:0043679axon terminusSlc1a1IDARatPMID:10701825|RGD:21201260
Cellular ComponentGO:0071944cell peripherySlc1a1IDARatPMID:10701825|RGD:21201260
Cellular ComponentGO:0071944cell peripherySlc1a1IDARatPMID:9542890|RGD:21201279
Cellular ComponentGO:0009986cell surfaceSlc1a1IDAMousePMID:20357106
Cellular ComponentGO:0009986cell surfaceSlc1a1IDAMousePMID:15009636
Cellular ComponentGO:0009986cell surfaceSlc1a1IDARatPMID:18096700|RGD:40902968
Cellular ComponentGO:0005737cytoplasmSlc1a1IDAMousePMID:20357106
Cellular ComponentGO:0030425dendriteSlc1a1IDAMousePMID:22539860
Cellular ComponentGO:0030425dendriteSlc1a1IDARatPMID:9334410|RGD:21201252
Cellular ComponentGO:0043198dendritic shaftSlc1a1IDARatPMID:10701825|RGD:21201260
Cellular ComponentGO:0043197dendritic spineSlc1a1IDARatPMID:10701825|RGD:21201260
Cellular ComponentGO:0043197dendritic spineSlc1a1IDARatPMID:9542890|RGD:21201279
Cellular ComponentGO:0150002distal dendriteSlc1a1IDARatPMID:9542890|RGD:21201279
Cellular ComponentGO:0031901early endosome membraneSlc1a1IDAMouseMGI:MGI:6304522|PMID:30840898
Cellular ComponentGO:0005783endoplasmic reticulumSlc1a1IDARatPMID:18096700|RGD:40902968
Cellular ComponentGO:0070062extracellular exosomeSLC1A1HDAHumanPMID:19056867
Cellular ComponentGO:0097386glial cell projectionSlc1a1IDARatPMID:9542890|RGD:21201279
Cellular ComponentGO:0016020membraneSLC1A1IDAHumanPMID:7914198
Cellular ComponentGO:0016020membraneSlc1a1IDAMousePMID:29350434
Cellular ComponentGO:0016020membraneSlc1a1IDARatPMID:26133720|RGD:11054956
Cellular ComponentGO:0045121membrane raftSlc1a1IDAMousePMID:15187084
Cellular ComponentGO:0043025neuronal cell bodySlc1a1IDAMousePMID:22539860
Cellular ComponentGO:0043025neuronal cell bodySlc1a1IDARatPMID:10701825|RGD:21201260
Cellular ComponentGO:0043025neuronal cell bodySlc1a1IDARatPMID:9542890|RGD:21201279
Cellular ComponentGO:0043204perikaryonSlc1a1IDARatPMID:9542890|RGD:21201279
Cellular ComponentGO:0099544perisynaptic spaceSlc1a1IDARatPMID:10701825|RGD:21201260
Cellular ComponentGO:0005886plasma membraneSLC1A1IDAHumanPMID:7914198
Cellular ComponentGO:0005886plasma membraneSLC1A1IDAHumanPMID:21123949
Cellular ComponentGO:0005886plasma membraneSLC1A1IMPHumanPMID:26690923
Cellular ComponentGO:0005886plasma membraneSLC1A1IMPHumanPMID:8857541
Cellular ComponentGO:0005886plasma membraneSlc1a1IDAMouseMGI:MGI:6304522|PMID:30840898
Cellular ComponentGO:0005886plasma membraneSlc1a1IDAMousePMID:17715130
Cellular ComponentGO:0005886plasma membraneSlc1a1IDAMousePMID:24412196
Cellular ComponentGO:0005886plasma membraneSlc1a1IDAMousePMID:15471567
Cellular ComponentGO:0005886plasma membraneSlc1a1IDAMousePMID:19364521
Cellular ComponentGO:0005886plasma membraneSlc1a1IPIUniProtKB:Q8R5J9MousePMID:18799673
Cellular ComponentGO:0005886plasma membraneSlc1a1IDAMousePMID:15009636
Cellular ComponentGO:0098793presynapseSlc1a1IDARatPMID:10701825|RGD:21201260
Cellular ComponentGO:1990635proximal dendriteSlc1a1IDARatPMID:9542890|RGD:21201279
Cellular ComponentGO:0055037recycling endosomeSlc1a1IDAMousePMID:20357106
Cellular ComponentGO:0055038recycling endosome membraneSlc1a1IDAMouseMGI:MGI:6304522|PMID:30840898
Cellular ComponentGO:0098685Schaffer collateral - CA1 synapseSlc1a1IMPMousePMID:19923291
Cellular ComponentGO:0098685Schaffer collateral - CA1 synapseSlc1a1IDAMousePMID:19923291
Cellular ComponentGO:0045202synapseSlc1a1IDAMousePMID:12710013
Cellular ComponentGO:0043083synaptic cleftSlc1a1IDARatPMID:10701825|RGD:21201260
Cellular ComponentGO:0031982vesicleSlc1a1IDAMousePMID:19364521
Biological ProcessGO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic processSlc1a1IDAMousePMID:16858406
Biological ProcessGO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic processSlc1a1IMPMousePMID:16858406
Biological ProcessGO:0032148activation of protein kinase B activitySlc1a1IMPMousePMID:23827345
Biological ProcessGO:0030534adult behaviorSlc1a1IMPMousePMID:28886095
Biological ProcessGO:0001662behavioral fear responseSlc1a1IMPMGI:MGI:2655190MousePMID:22732503
Biological ProcessGO:0001662behavioral fear responseSlc1a1IMPMousePMID:22221107
Biological ProcessGO:0048514blood vessel morphogenesisSlc1a1IMPMouseMGI:MGI:6393184|PMID:25350110
Biological ProcessGO:0007420brain developmentSlc1a1IMPMousePMID:28886095
Biological ProcessGO:0071242cellular response to ammonium ionSlc1a1IMPMGI:MGI:2655190MousePMID:24412196
Biological ProcessGO:0071242cellular response to ammonium ionSlc1a1IDAMousePMID:24412196
Biological ProcessGO:1903926cellular response to bisphenol ASlc1a1IDAMousePMID:21980460
Biological ProcessGO:0071314cellular response to cocaineSlc1a1IDAMousePMID:27208619
Biological ProcessGO:0071288cellular response to mercury ionSlc1a1IDAMousePMID:15635608
Biological ProcessGO:0071407cellular response to organic cyclic compoundSLC1A1IDAHumanPMID:12562531
Biological ProcessGO:0034599cellular response to oxidative stressSlc1a1IMPMGI:MGI:2655190MousePMID:22732503
Biological ProcessGO:1902476chloride transmembrane transportSLC1A1IMPHumanPMID:8857541
Biological ProcessGO:1990708conditioned place preferenceSlc1a1IMPMGI:2655190MousePMID:28049029
Biological ProcessGO:1903712cysteine transmembrane transportSlc1a1IDAMouseMGI:MGI:6304522|PMID:30840898
Biological ProcessGO:0042883cysteine transportSLC1A1IDAHumanPMID:21123949
Biological ProcessGO:0001816cytokine productionSlc1a1IMPMousePMID:28886095
Biological ProcessGO:0019221cytokine-mediated signaling pathwaySlc1a1IMPMousePMID:28886095
Biological ProcessGO:0070779D-aspartate import across plasma membraneSLC1A1IDAHumanPMID:7521911
Biological ProcessGO:0070779D-aspartate import across plasma membraneSLC1A1IMPHumanPMID:8857541
Biological ProcessGO:0070777D-aspartate transportSLC1A1IDAHumanPMID:7914198
Biological ProcessGO:0042417dopamine metabolic processSlc1a1IMPMousePMID:28507136
Biological ProcessGO:0007212dopamine receptor signaling pathwaySlc1a1IMPMousePMID:29229708
Biological ProcessGO:0007212dopamine receptor signaling pathwaySlc1a1IMPMousePMID:28507136
Biological ProcessGO:0045184establishment of protein localizationSlc1a1IMPMGI:MGI:2655190MousePMID:19923291
Biological ProcessGO:0010467gene expressionSlc1a1IMPMousePMID:28507136
Biological ProcessGO:0007215glutamate receptor signaling pathwaySlc1a1IMPMousePMID:29229708
Biological ProcessGO:0006750glutathione biosynthetic processSlc1a1IDAMousePMID:12614333
Biological ProcessGO:0006749glutathione metabolic processSlc1a1IMPMousePMID:28886095
Biological ProcessGO:0006749glutathione metabolic processSlc1a1IMPMGI:MGI:2655190MousePMID:22732503
Biological ProcessGO:0006749glutathione metabolic processSlc1a1IMPMousePMID:18799673
Biological ProcessGO:0007625grooming behaviorSlc1a1IMPMousePMID:28507136
Biological ProcessGO:0060047heart contractionSlc1a1IMPMGI:MGI:2655190MousePMID:23361868
Biological ProcessGO:0090461intracellular glutamate homeostasisSlc1a1IMPMGI:MGI:2655190MousePMID:19923291
Biological ProcessGO:0006882intracellular zinc ion homeostasisSlc1a1IMPMousePMID:22575539
Biological ProcessGO:0006882intracellular zinc ion homeostasisSlc1a1IMPMGI:MGI:2655190MousePMID:21084597
Biological ProcessGO:0140009L-aspartate import across plasma membraneSLC1A1IDAHumanPMID:7521911
Biological ProcessGO:0140009L-aspartate import across plasma membraneSLC1A1IMPHumanPMID:8857541
Biological ProcessGO:0070778L-aspartate transmembrane transportSLC1A1IDAHumanPMID:7914198
Biological ProcessGO:0051938L-glutamate importSLC1A1IDAHumanPMID:7521911
Biological ProcessGO:0098712L-glutamate import across plasma membraneSLC1A1IDAHumanPMID:26690923
Biological ProcessGO:0098712L-glutamate import across plasma membraneSLC1A1IMPHumanPMID:8857541
Biological ProcessGO:0098712L-glutamate import across plasma membraneSlc1a1IDAMousePMID:16858406
Biological ProcessGO:0098712L-glutamate import across plasma membraneSlc1a1IMPMGI:MGI:2655190MousePMID:15140926
Biological ProcessGO:0098712L-glutamate import across plasma membraneSlc1a1IMPMousePMID:16858406
Biological ProcessGO:0098712L-glutamate import across plasma membraneSlc1a1IDAMousePMID:11030592
Biological ProcessGO:0098712L-glutamate import across plasma membraneSlc1a1IMPMGI:MGI:2655190MousePMID:19766171
Biological ProcessGO:0015813L-glutamate transmembrane transportSLC1A1IDAHumanPMID:21123949
Biological ProcessGO:0015813L-glutamate transmembrane transportSLC1A1IDAHumanPMID:26690923
Biological ProcessGO:0015813L-glutamate transmembrane transportSLC1A1IDAHumanPMID:7914198
Biological ProcessGO:0015813L-glutamate transmembrane transportSlc1a1IDAMousePMID:15009636
Biological ProcessGO:0015813L-glutamate transmembrane transportSlc1a1IDARatPMID:16128593|RGD:1599319
Biological ProcessGO:0007611learning or memorySlc1a1IMPMousePMID:22221107
Biological ProcessGO:0007611learning or memorySlc1a1IMPMGI:MGI:2655190MousePMID:24797327
Biological ProcessGO:0007626locomotory behaviorSlc1a1IMPMousePMID:28507136
Biological ProcessGO:0060291long-term synaptic potentiationSlc1a1IMPMGI:MGI:2655190MousePMID:19923291
Biological ProcessGO:0060291long-term synaptic potentiationSlc1a1IMPMousePMID:29229708
Biological ProcessGO:0035633maintenance of blood-brain barrierSlc1a1IMPMouseMGI:MGI:6393184|PMID:25350110
Biological ProcessGO:0007613memorySlc1a1IMPMousePMID:28886095
Biological ProcessGO:0061744motor behaviorSlc1a1IMPMousePMID:28886095
Biological ProcessGO:0061744motor behaviorSlc1a1IMPMousePMID:29229708
Biological ProcessGO:0097049motor neuron apoptotic processSlc1a1IDAMousePMID:16858406
Biological ProcessGO:0097049motor neuron apoptotic processSlc1a1IMPMGI:MGI:2655190MousePMID:16858406
Biological ProcessGO:0043524negative regulation of neuron apoptotic processSlc1a1IMPMGI:MGI:2655190MousePMID:29720605
Biological ProcessGO:0022008neurogenesisSlc1a1IMPMGI:MGI:2655190MousePMID:29720605
Biological ProcessGO:0051402neuron apoptotic processSlc1a1IMPMousePMID:27040821
Biological ProcessGO:0036475neuron death in response to oxidative stressSlc1a1IMPMouseMGI:MGI:6393184|PMID:25350110
Biological ProcessGO:0098877neurotransmitter receptor transport to plasma membraneSlc1a1IMPMGI:MGI:2655190MousePMID:24797327
Biological ProcessGO:0098877neurotransmitter receptor transport to plasma membraneSlc1a1IMPMGI:MGI:2655190MousePMID:24412196
Biological ProcessGO:0018105peptidyl-serine phosphorylationSlc1a1IMPMGI:MGI:2655190MousePMID:24412196
Biological ProcessGO:0010460positive regulation of heart rateSlc1a1IMPMouseMGI:MGI:5584094|PMID:23361868
Biological ProcessGO:0099170postsynaptic modulation of chemical synaptic transmissionSlc1a1IDAMousePMID:19923291
Biological ProcessGO:0099170postsynaptic modulation of chemical synaptic transmissionSlc1a1IMPMousePMID:19923291
Biological ProcessGO:0002027regulation of heart rateSlc1a1IMPMGI:MGI:2655190MousePMID:23361868
Biological ProcessGO:0001932regulation of protein phosphorylationSlc1a1IMPMGI:MGI:2655190MousePMID:24412196
Biological ProcessGO:0090313regulation of protein targeting to membraneSlc1a1IMPMGI:MGI:2655190MousePMID:24412196
Biological ProcessGO:0001975response to amphetamineSlc1a1IMPMousePMID:28507136
Biological ProcessGO:0072347response to anestheticSlc1a1IMPMGI:MGI:2655190MousePMID:24797327
Biological ProcessGO:0072347response to anestheticSlc1a1IMPMousePMID:22221107
Biological ProcessGO:0072347response to anestheticSlc1a1IMPMousePMID:23827345
Biological ProcessGO:0048678response to axon injurySlc1a1IMPMousePMID:27040821
Biological ProcessGO:0048678response to axon injurySlc1a1IMPMousePMID:23827345
Biological ProcessGO:0048678response to axon injurySlc1a1IDAMousePMID:16858406
Biological ProcessGO:0048678response to axon injurySlc1a1IMPMGI:MGI:2655190MousePMID:16858406
Biological ProcessGO:0048678response to axon injurySlc1a1IMPMousePMID:22575539
Biological ProcessGO:0036293response to decreased oxygen levelsSlc1a1IMPMGI:MGI:2655190MousePMID:25350110
Biological ProcessGO:0036293response to decreased oxygen levelsSlc1a1IMPMGI:MGI:2655190MousePMID:29720605
Biological ProcessGO:0043278response to morphineSlc1a1IMPMGI:2655190MousePMID:28049029
Biological ProcessGO:0043278response to morphineSlc1a1IDAMousePMID:28049029
Biological ProcessGO:0009410response to xenobiotic stimulusSlc1a1IMPMousePMID:24334055
Biological ProcessGO:0009410response to xenobiotic stimulusSlc1a1IMPMGI:MGI:2655190MousePMID:20875840
Biological ProcessGO:0060041retina development in camera-type eyeSlc1a1IMPMousePMID:28703795
Biological ProcessGO:0010842retina layer formationSlc1a1IMPMGI:MGI:2655190MousePMID:19766171
Biological ProcessGO:0010842retina layer formationSlc1a1IMPMGI:MGI:2655190MousePMID:29677370
Biological ProcessGO:0060013righting reflexSlc1a1IMPMGI:MGI:2655190MousePMID:20875840
Biological ProcessGO:0006801superoxide metabolic processSlc1a1IMPMousePMID:27040821
Biological ProcessGO:0050808synapse organizationSlc1a1IMPMousePMID:28886095
Biological ProcessGO:0071577zinc ion transmembrane transportSlc1a1IMPMousePMID:27040821

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory