Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC1A2
  • Mouse genes Slc1a2
  • Rat genes Slc1a2
  • Zfish genes slc1a2a,slc1a2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc1a2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0033229	cysteine transmembrane transporter activity	Slc1a2	IDA		Mouse	PMID:12614333
Molecular Function	GO:0015501	glutamate:sodium symporter activity	SLC1A2	IDA		Human	PMID:15265858
Molecular Function	GO:0015501	glutamate:sodium symporter activity	Slc1a2	IDA		Mouse	PMID:7698742
Molecular Function	GO:0015501	glutamate:sodium symporter activity	Slc1a2	IDA		Rat	PMID:1448170|RGD:70006
Molecular Function	GO:0005314	high-affinity L-glutamate transmembrane transporter activity	SLC1A2	IDA		Human	PMID:26690923
Molecular Function	GO:0005314	high-affinity L-glutamate transmembrane transporter activity	Slc1a2	IDA		Mouse	MGI:MGI:1098956|PMID:9373176
Molecular Function	GO:0005314	high-affinity L-glutamate transmembrane transporter activity	Slc1a2	IMP		Rat	PMID:10899959|RGD:1642938
Molecular Function	GO:0005314	high-affinity L-glutamate transmembrane transporter activity	Slc1a2	IDA		Rat	PMID:1448170|RGD:70006
Molecular Function	GO:0005313	L-glutamate transmembrane transporter activity	SLC1A2	IDA		Human	PMID:7521911
Molecular Function	GO:0005313	L-glutamate transmembrane transporter activity	Slc1a2	IMP		Mouse	PMID:15009636
Molecular Function	GO:0005313	L-glutamate transmembrane transporter activity	Slc1a2	IDA		Mouse	PMID:24307171
Molecular Function	GO:0008509	monoatomic anion transmembrane transporter activity	Slc1a2	IDA		Mouse	PMID:24307171
Molecular Function	GO:0005515	protein binding	SLC1A2	IPI	UniProtKB:P10636	Human	PMID:19527721
Molecular Function	GO:0005515	protein binding	SLC1A2	IPI	UniProtKB:P42858	Human	PMID:32814053
Cellular Component	GO:0097449	astrocyte projection	Slc1a2	IDA		Mouse	MGI:MGI:5629870|PMID:25716834
Cellular Component	GO:0097449	astrocyte projection	Slc1a2	IDA		Rat	PMID:9334410|RGD:21201252
Cellular Component	GO:0030673	axolemma	Slc1a2	IDA		Mouse	PMID:9671661
Cellular Component	GO:0030424	axon	Slc1a2	IDA		Mouse	PMID:9671661
Cellular Component	GO:0044297	cell body	Slc1a2	IDA		Mouse	MGI:MGI:5629870|PMID:25716834
Cellular Component	GO:0044297	cell body	Slc1a2	IDA		Rat	PMID:9334410|RGD:21201252
Cellular Component	GO:0009986	cell surface	SLC1A2	IDA		Human	PMID:21399631
Cellular Component	GO:0044316	cone cell pedicle	slc1a2a	IDA		Zfish	PMID:28612046
Cellular Component	GO:0043198	dendritic shaft	Slc1a2	IDA		Rat	PMID:11896154|RGD:619547
Cellular Component	GO:0043197	dendritic spine	Slc1a2	IDA		Rat	PMID:11950769|RGD:727361
Cellular Component	GO:0098978	glutamatergic synapse	Slc1a2	IMP		Mouse	PMID:25834045
Cellular Component	GO:0016020	membrane	Slc1a2	IDA		Mouse	PMID:29350434
Cellular Component	GO:0098796	membrane protein complex	SLC1A2	IDA		Human	PMID:20193040
Cellular Component	GO:0098796	membrane protein complex	Slc1a2	IDA		Rat	PMID:9334410|RGD:21201252
Cellular Component	GO:0045121	membrane raft	SLC1A2	IDA		Human	PMID:20193040
Cellular Component	GO:0045121	membrane raft	Slc1a2	IGI	UniProtKB:P05067	Mouse	MGI:MGI:6393037|PMID:20193040
Cellular Component	GO:0045121	membrane raft	Slc1a2	IDA		Mouse	PMID:15187084
Cellular Component	GO:0043005	neuron projection	Slc1a2	IDA		Rat	PMID:9786982|RGD:1642937
Cellular Component	GO:0044306	neuron projection terminus	Slc1a2	IDA		Mouse	PMID:12558972
Cellular Component	GO:0005886	plasma membrane	SLC1A2	IMP		Human	PMID:15265858
Cellular Component	GO:0005886	plasma membrane	SLC1A2	IMP		Human	PMID:26690923
Cellular Component	GO:0005886	plasma membrane	Slc1a2	IMP		Mouse	MGI:MGI:1098956|PMID:9373176
Cellular Component	GO:0005886	plasma membrane	Slc1a2	IDA		Mouse	PMID:19364521
Cellular Component	GO:0005886	plasma membrane	Slc1a2	IDA		Mouse	PMID:24307171
Cellular Component	GO:0005886	plasma membrane	Slc1a2	IMP		Rat	PMID:1448170|RGD:70006
Cellular Component	GO:0005886	plasma membrane	Slc1a2	IDA		Rat	PMID:9786982|RGD:1642937
Cellular Component	GO:0098793	presynapse	slc1a2a	IDA		Zfish	PMID:28612046
Cellular Component	GO:0042734	presynaptic membrane	SLC1A2	IDA		Human	PMID:21258616
Cellular Component	GO:0042734	presynaptic membrane	Slc1a2	IDA		Rat	PMID:11896154|RGD:619547
Cellular Component	GO:0045202	synapse	Slc1a2	IDA		Mouse	PMID:12558972
Cellular Component	GO:0045202	synapse	Slc1a2	IDA		Rat	PMID:11950769|RGD:727361
Cellular Component	GO:0031982	vesicle	Slc1a2	IDA		Mouse	PMID:19364521
Biological Process	GO:0030534	adult behavior	Slc1a2	IMP	MGI:MGI:2449707	Mouse	PMID:9180080
Biological Process	GO:0071314	cellular response to cocaine	Slc1a2	IDA		Mouse	PMID:27208619
Biological Process	GO:0031668	cellular response to extracellular stimulus	Slc1a2	IMP	MGI:MGI:2449707	Mouse	PMID:16197522
Biological Process	GO:0070779	D-aspartate import across plasma membrane	SLC1A2	IDA		Human	PMID:7521911
Biological Process	GO:0006750	glutathione biosynthetic process	Slc1a2	IDA		Mouse	PMID:12614333
Biological Process	GO:0140009	L-aspartate import across plasma membrane	SLC1A2	IDA		Human	PMID:7521911
Biological Process	GO:0098712	L-glutamate import across plasma membrane	SLC1A2	IDA		Human	PMID:15265858
Biological Process	GO:0098712	L-glutamate import across plasma membrane	SLC1A2	IGI	UniProtKB:Q9WVK8	Human	PMID:20193040
Biological Process	GO:0098712	L-glutamate import across plasma membrane	SLC1A2	IDA		Human	PMID:26690923
Biological Process	GO:0098712	L-glutamate import across plasma membrane	SLC1A2	IDA		Human	PMID:7521911
Biological Process	GO:0098712	L-glutamate import across plasma membrane	Slc1a2	IDA		Mouse	MGI:MGI:1098956|PMID:9373176
Biological Process	GO:0098712	L-glutamate import across plasma membrane	Slc1a2	IMP		Mouse	PMID:15140926
Biological Process	GO:0015813	L-glutamate transmembrane transport	SLC1A2	IDA		Human	PMID:26690923
Biological Process	GO:0015813	L-glutamate transmembrane transport	Slc1a2	IDA		Mouse	PMID:7698742
Biological Process	GO:0015813	L-glutamate transmembrane transport	Slc1a2	IMP		Mouse	PMID:15009636
Biological Process	GO:0015813	L-glutamate transmembrane transport	Slc1a2	IDA		Mouse	PMID:24307171
Biological Process	GO:0015813	L-glutamate transmembrane transport	Slc1a2	IMP		Rat	PMID:10899959|RGD:1642938
Biological Process	GO:0008345	larval locomotory behavior	slc1a2b	IMP	ZFIN:ZDB-MRPHLNO-120217-2	Zfish	PMID:22094018
Biological Process	GO:0008345	larval locomotory behavior	slc1a2b	IMP	ZFIN:ZDB-GENO-980202-1074	Zfish	PMID:22094018
Biological Process	GO:0098656	monoatomic anion transmembrane transport	Slc1a2	IDA		Mouse	PMID:24307171
Biological Process	GO:0035264	multicellular organism growth	Slc1a2	IMP	MGI:MGI:2449707	Mouse	PMID:9180080
Biological Process	GO:0007399	nervous system development	Slc1a2	IMP	MGI:MGI:2449707	Mouse	PMID:9180080
Biological Process	GO:0098810	neurotransmitter reuptake	Slc1a2	IMP		Mouse	PMID:25834045
Biological Process	GO:0046326	positive regulation of glucose import	Slc1a2	IMP	MGI:MGI:2449707	Mouse	PMID:16197522
Biological Process	GO:0070207	protein homotrimerization	SLC1A2	IDA		Human	PMID:15265858
Biological Process	GO:0070207	protein homotrimerization	SLC1A2	IDA		Human	PMID:15483603
Biological Process	GO:0043200	response to amino acid	Slc1a2	IMP	MGI:MGI:2449707	Mouse	PMID:9180080
Biological Process	GO:0009416	response to light stimulus	Slc1a2	IMP	MGI:MGI:2449707	Mouse	PMID:9539795
Biological Process	GO:0009611	response to wounding	Slc1a2	IMP	MGI:MGI:2449707	Mouse	PMID:9180080
Biological Process	GO:0009410	response to xenobiotic stimulus	Slc1a2	IMP	MGI:MGI:2449707	Mouse	PMID:9180080
Biological Process	GO:0009410	response to xenobiotic stimulus	Slc1a2	IMP	MGI:MGI:2449707	Mouse	PMID:9539795
Biological Process	GO:0021537	telencephalon development	Slc1a2	IMP	MGI:MGI:2449707	Mouse	PMID:9180080
Biological Process	GO:0007632	visual behavior	Slc1a2	IMP	MGI:MGI:2449707	Mouse	PMID:16197522

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern