Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Slc1a3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SLC1A3
- Mouse genes Slc1a3
- Rat genes Slc1a3
- Zfish genes slc1a3a,slc1a3b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc1a3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015172	acidic amino acid transmembrane transporter activity	Slc1a3	IMP		Mouse	MGI:MGI:5897520\|PMID:28032905
Molecular Function	GO:0016597	amino acid binding	Slc1a3	IDA		Mouse	PMID:7903437
Molecular Function	GO:0016595	glutamate binding	Slc1a3	IDA		Mouse	PMID:7903437
Molecular Function	GO:0015501	glutamate:sodium symporter activity	SLC1A3	IDA		Human	PMID:20477940
Molecular Function	GO:0015501	glutamate:sodium symporter activity	SLC1A3	IMP		Human	PMID:8123008
Molecular Function	GO:0015501	glutamate:sodium symporter activity	Slc1a3	IMP		Rat	PMID:1279699\|RGD:70007
Molecular Function	GO:0005314	high-affinity L-glutamate transmembrane transporter activity	SLC1A3	IDA		Human	PMID:26690923
Molecular Function	GO:0005314	high-affinity L-glutamate transmembrane transporter activity	SLC1A3	IMP		Human	PMID:28032905
Molecular Function	GO:0005314	high-affinity L-glutamate transmembrane transporter activity	SLC1A3	IMP		Human	PMID:8123008
Molecular Function	GO:0005314	high-affinity L-glutamate transmembrane transporter activity	Slc1a3	IDA		Mouse	PMID:14723703
Molecular Function	GO:0005314	high-affinity L-glutamate transmembrane transporter activity	Slc1a3	IDA		Mouse	PMID:7903437
Molecular Function	GO:0005314	high-affinity L-glutamate transmembrane transporter activity	Slc1a3	IMP	MGI:MGI:1931872	Mouse	PMID:15390100
Molecular Function	GO:0005314	high-affinity L-glutamate transmembrane transporter activity	Slc1a3	IMP		Rat	PMID:10899959\|RGD:1642938
Molecular Function	GO:0005314	high-affinity L-glutamate transmembrane transporter activity	Slc1a3	IMP		Rat	PMID:1279699\|RGD:70007
Molecular Function	GO:0005313	L-glutamate transmembrane transporter activity	SLC1A3	IDA		Human	PMID:7521911
Molecular Function	GO:0005313	L-glutamate transmembrane transporter activity	Slc1a3	IDA		Rat	PMID:15242733\|RGD:1642939
Molecular Function	GO:0005515	protein binding	SLC1A3	IPI	UniProtKB:A0PK00	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC1A3	IPI	UniProtKB:O14880	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC1A3	IPI	UniProtKB:Q5BJH2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC1A3	IPI	UniProtKB:Q8WVV5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Slc1a3	IPI	PR:P42208	Mouse	PMID:14723703
Cellular Component	GO:0009925	basal plasma membrane	Slc1a3	IDA		Rat	PMID:26133720\|RGD:11054956
Cellular Component	GO:0016323	basolateral plasma membrane	Slc1a3	IDA		Rat	PMID:9219972\|RGD:2301545
Cellular Component	GO:0071944	cell periphery	Slc1a3	IDA		Mouse	PMID:20531390
Cellular Component	GO:0042995	cell projection	Slc1a3	IDA		Mouse	PMID:12971893
Cellular Component	GO:0042995	cell projection	Slc1a3	IDA		Mouse	PMID:15965470
Cellular Component	GO:0042995	cell projection	Slc1a3	IDA		Mouse	PMID:14723703
Cellular Component	GO:0042995	cell projection	Slc1a3	IDA		Mouse	PMID:9671661
Cellular Component	GO:0009986	cell surface	Slc1a3	IDA		Mouse	PMID:14723703
Cellular Component	GO:0043197	dendritic spine	Slc1a3	IDA		Rat	PMID:11950769\|RGD:727361
Cellular Component	GO:0098796	membrane protein complex	Slc1a3	IDA		Rat	PMID:9334410\|RGD:21201252
Cellular Component	GO:0005743	mitochondrial inner membrane	Slc1a3	IDA		Rat	PMID:15242733\|RGD:1642939
Cellular Component	GO:0043005	neuron projection	Slc1a3	IDA		Mouse	PMID:20531390
Cellular Component	GO:0043005	neuron projection	Slc1a3	IDA		Rat	PMID:9786982\|RGD:1642937
Cellular Component	GO:0043005	neuron projection	Slc1a3	IDA		Rat	PMID:26133720\|RGD:11054956
Cellular Component	GO:0043025	neuronal cell body	Slc1a3	IDA		Mouse	PMID:11133151
Cellular Component	GO:0043025	neuronal cell body	Slc1a3	IDA		Mouse	PMID:15965470
Cellular Component	GO:0043025	neuronal cell body	Slc1a3	IDA		Mouse	PMID:12971893
Cellular Component	GO:0043025	neuronal cell body	Slc1a3	IDA		Mouse	PMID:9364068
Cellular Component	GO:0043025	neuronal cell body	Slc1a3	IDA		Rat	PMID:26133720\|RGD:11054956
Cellular Component	GO:0005886	plasma membrane	SLC1A3	IMP		Human	PMID:26690923
Cellular Component	GO:0005886	plasma membrane	SLC1A3	IMP		Human	PMID:28032905
Cellular Component	GO:0005886	plasma membrane	SLC1A3	IMP		Human	PMID:8123008
Cellular Component	GO:0005886	plasma membrane	Slc1a3	IDA		Mouse	MGI:MGI:5897520\|PMID:28032905
Cellular Component	GO:0005886	plasma membrane	Slc1a3	IDA		Mouse	PMID:14723703
Cellular Component	GO:0005886	plasma membrane	Slc1a3	IMP		Rat	PMID:1279699\|RGD:70007
Cellular Component	GO:0005886	plasma membrane	Slc1a3	IDA		Rat	PMID:9786982\|RGD:1642937
Cellular Component	GO:0045202	synapse	Slc1a3	IDA		Mouse	PMID:12558972
Cellular Component	GO:0045202	synapse	Slc1a3	IDA		Rat	PMID:11950769\|RGD:727361
Biological Process	GO:0031223	auditory behavior	Slc1a3	IMP	MGI:MGI:1931872	Mouse	PMID:11102482
Biological Process	GO:0048667	cell morphogenesis involved in neuron differentiation	Slc1a3	IMP	MGI:MGI:1931872	Mouse	PMID:9753165
Biological Process	GO:0071314	cellular response to cocaine	Slc1a3	IDA		Mouse	PMID:27208619
Biological Process	GO:1902476	chloride transmembrane transport	SLC1A3	IDA		Human	PMID:20477940
Biological Process	GO:0021545	cranial nerve development	Slc1a3	IMP	MGI:MGI:1931872	Mouse	PMID:9753165
Biological Process	GO:0070779	D-aspartate import across plasma membrane	SLC1A3	IMP		Human	PMID:28032905
Biological Process	GO:0070779	D-aspartate import across plasma membrane	SLC1A3	IDA		Human	PMID:7521911
Biological Process	GO:0070779	D-aspartate import across plasma membrane	SLC1A3	IMP		Human	PMID:8123008
Biological Process	GO:0070779	D-aspartate import across plasma membrane	Slc1a3	IMP		Mouse	MGI:MGI:5897520\|PMID:28032905
Biological Process	GO:0009449	gamma-aminobutyric acid biosynthetic process	Slc1a3	IMP	MGI:MGI:1931872	Mouse	PMID:15305132
Biological Process	GO:0006883	intracellular sodium ion homeostasis	Slc1a3	IMP	MGI:MGI:1931872	Mouse	PMID:19766171
Biological Process	GO:0140009	L-aspartate import across plasma membrane	SLC1A3	IDA		Human	PMID:20477940
Biological Process	GO:0140009	L-aspartate import across plasma membrane	SLC1A3	IDA		Human	PMID:7521911
Biological Process	GO:0140009	L-aspartate import across plasma membrane	SLC1A3	IMP		Human	PMID:8123008
Biological Process	GO:0140009	L-aspartate import across plasma membrane	Slc1a3	IMP		Rat	PMID:1279699\|RGD:70007
Biological Process	GO:0051938	L-glutamate import	SLC1A3	IDA		Human	PMID:7521911
Biological Process	GO:0051938	L-glutamate import	Slc1a3	IMP	MGI:MGI:1931872	Mouse	PMID:15390100
Biological Process	GO:0098712	L-glutamate import across plasma membrane	SLC1A3	IDA		Human	PMID:26690923
Biological Process	GO:0098712	L-glutamate import across plasma membrane	SLC1A3	IMP		Human	PMID:28032905
Biological Process	GO:0098712	L-glutamate import across plasma membrane	SLC1A3	IMP		Human	PMID:8123008
Biological Process	GO:0098712	L-glutamate import across plasma membrane	Slc1a3	IMP	MGI:MGI:1931872	Mouse	PMID:15140926
Biological Process	GO:0098712	L-glutamate import across plasma membrane	Slc1a3	IMP	MGI:MGI:1931872	Mouse	PMID:19766171
Biological Process	GO:0098712	L-glutamate import across plasma membrane	Slc1a3	IMP		Rat	PMID:1279699\|RGD:70007
Biological Process	GO:0015813	L-glutamate transmembrane transport	SLC1A3	IDA		Human	PMID:26690923
Biological Process	GO:0015813	L-glutamate transmembrane transport	Slc1a3	IDA		Mouse	PMID:14723703
Biological Process	GO:0015813	L-glutamate transmembrane transport	Slc1a3	IDA		Rat	PMID:7723632\|RGD:8553776
Biological Process	GO:0015813	L-glutamate transmembrane transport	Slc1a3	IMP		Rat	PMID:10899959\|RGD:1642938
Biological Process	GO:0015813	L-glutamate transmembrane transport	Slc1a3	IDA		Rat	PMID:15242733\|RGD:1642939
Biological Process	GO:0043490	malate-aspartate shuttle	Slc1a3	IDA		Rat	PMID:15242733\|RGD:1642939
Biological Process	GO:0050885	neuromuscular process controlling balance	Slc1a3	IMP	MGI:MGI:1931872	Mouse	PMID:9753165
Biological Process	GO:0050806	positive regulation of synaptic transmission	Slc1a3	IMP	MGI:MGI:1931872	Mouse	PMID:9539795
Biological Process	GO:0071805	potassium ion transmembrane transport	SLC1A3	IDA		Human	PMID:20477940
Biological Process	GO:0046677	response to antibiotic	Slc1a3	IMP	MGI:MGI:1931872	Mouse	PMID:15862894
Biological Process	GO:0010035	response to inorganic substance	Slc1a3	IDA		Rat	PMID:7723632\|RGD:8553776
Biological Process	GO:0009416	response to light stimulus	Slc1a3	IMP	MGI:MGI:1931872	Mouse	PMID:9539795
Biological Process	GO:0009611	response to wounding	Slc1a3	IMP	MGI:MGI:1931872	Mouse	PMID:9753165
Biological Process	GO:0009410	response to xenobiotic stimulus	Slc1a3	IMP	MGI:MGI:1931872	Mouse	PMID:9539795
Biological Process	GO:0007605	sensory perception of sound	Slc1a3	IMP	MGI:MGI:1931872	Mouse	PMID:11102482

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.