Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC1A6
  • Mouse genes Slc1a6
  • Rat genes Slc1a6
  • Zfish genes slc1a6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc1a6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015501	glutamate:sodium symporter activity	SLC1A6	IDA		Human	PMID:7791878
Molecular Function	GO:0005314	high-affinity L-glutamate transmembrane transporter activity	Slc1a6	IDA		Rat	PMID:26690923|RGD:12907562
Molecular Function	GO:0015183	L-aspartate transmembrane transporter activity	SLC1A6	IDA		Human	PMID:7791878
Molecular Function	GO:0005313	L-glutamate transmembrane transporter activity	SLC1A6	IDA		Human	PMID:7791878
Molecular Function	GO:0005313	L-glutamate transmembrane transporter activity	Slc1a6	IMP	MGI:MGI:3027689	Mouse	PMID:14715943
Molecular Function	GO:0008509	monoatomic anion transmembrane transporter activity	Slc1a6	IDA		Rat	PMID:11950769|RGD:727361
Cellular Component	GO:0098978	glutamatergic synapse	Slc1a6	IDA		Mouse	PMID:23049999
Cellular Component	GO:0005794	Golgi apparatus	Slc1a6	IDA		Mouse	PMID:20231455
Cellular Component	GO:0045111	intermediate filament cytoskeleton	SLC1A6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	Slc1a6	IDA		Mouse	PMID:20231455
Cellular Component	GO:0098796	membrane protein complex	Slc1a6	IDA		Rat	PMID:9334410|RGD:21201252
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	Slc1a6	IDA		Rat	PMID:9570792|RGD:13702209
Cellular Component	GO:0005886	plasma membrane	SLC1A6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Slc1a6	IMP		Rat	PMID:26690923|RGD:12907562
Cellular Component	GO:0045211	postsynaptic membrane	Slc1a6	IDA		Rat	PMID:9570792|RGD:13702209
Cellular Component	GO:0042734	presynaptic membrane	Slc1a6	IDA		Mouse	PMID:23049999
Biological Process	GO:0051649	establishment of localization in cell	Slc1a6	IMP	MGI:MGI:3027689	Mouse	PMID:14715943
Biological Process	GO:0140009	L-aspartate import across plasma membrane	SLC1A6	IDA		Human	PMID:7791878
Biological Process	GO:0098712	L-glutamate import across plasma membrane	SLC1A6	IDA		Human	PMID:7791878
Biological Process	GO:0098712	L-glutamate import across plasma membrane	Slc1a6	IDA		Rat	PMID:26690923|RGD:12907562
Biological Process	GO:0015813	L-glutamate transmembrane transport	Slc1a6	IMP	MGI:MGI:3027689	Mouse	PMID:14715943
Biological Process	GO:0015813	L-glutamate transmembrane transport	Slc1a6	IDA		Rat	PMID:26690923|RGD:12907562
Biological Process	GO:0001504	neurotransmitter uptake	SLC1A6	IDA		Human	PMID:7791878
Biological Process	GO:0001504	neurotransmitter uptake	SLC1A6	IMP		Human	PMID:7791878
Biological Process	GO:0042391	regulation of membrane potential	Slc1a6	IMP	MGI:MGI:3027689	Mouse	PMID:14715943

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern