Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC22A12
  • Mouse genes Slc22a12
  • Rat genes Slc22a12
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc22a12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030165	PDZ domain binding	SLC22A12	IPI	UniProtKB:Q5T2W1	Human	PMID:15304510
Molecular Function	GO:0005515	protein binding	Slc22a12	IPI	UniProtKB:Q9JIL4	Mouse	MGI:MGI:3690142|PMID:14531806
Molecular Function	GO:0015143	urate transmembrane transporter activity	SLC22A12	IDA		Human	PMID:12024214
Molecular Function	GO:0015143	urate transmembrane transporter activity	Slc22a12	IDA		Mouse	PMID:14747372
Cellular Component	GO:0016324	apical plasma membrane	SLC22A12	IDA		Human	PMID:12024214
Cellular Component	GO:0016324	apical plasma membrane	Slc22a12	IDA		Rat	PMID:21074513|RGD:126781733
Cellular Component	GO:0016324	apical plasma membrane	Slc22a12	IDA		Rat	PMID:28679589|RGD:13439745
Cellular Component	GO:0031526	brush border membrane	Slc22a12	IDA		Mouse	PMID:14747372
Cellular Component	GO:0070062	extracellular exosome	SLC22A12	HDA		Human	PMID:19056867
Cellular Component	GO:0016020	membrane	SLC22A12	IDA		Human	PMID:12024214
Cellular Component	GO:0016020	membrane	Slc22a12	IDA		Mouse	PMID:14747372
Cellular Component	GO:0005886	plasma membrane	SLC22A12	IDA		Human	PMID:14694169
Cellular Component	GO:0005886	plasma membrane	SLC22A12	IDA		Human	PMID:16775029
Cellular Component	GO:0005886	plasma membrane	SLC22A12	IMP		Human	PMID:22194875
Biological Process	GO:0032869	cellular response to insulin stimulus	Slc22a12	IEP		Rat	PMID:28679589|RGD:13439745
Biological Process	GO:0097744	renal urate salt excretion	Slc22a12	IEP		Rat	PMID:28679589|RGD:13439745
Biological Process	GO:0009410	response to xenobiotic stimulus	SLC22A12	IDA		Human	PMID:12024214
Biological Process	GO:0046415	urate metabolic process	SLC22A12	IMP		Human	PMID:19503597
Biological Process	GO:0015747	urate transport	SLC22A12	IDA		Human	PMID:12024214
Biological Process	GO:0015747	urate transport	SLC22A12	IDA		Human	PMID:16775029
Biological Process	GO:0015747	urate transport	SLC22A12	IMP		Human	PMID:22194875
Biological Process	GO:0015747	urate transport	Slc22a12	IDA		Mouse	PMID:14747372
Biological Process	GO:0015747	urate transport	Slc22a12	IDA		Rat	PMID:21074513|RGD:126781733

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern