Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Slc25a4

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SLC25A4
- Mouse genes Slc25a4
- Rat genes Slc25a4
- Zfish genes slc25a4
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc25a4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005471	ATP:ADP antiporter activity	SLC25A4	IDA		Human	PMID:21586654
Molecular Function	GO:0005471	ATP:ADP antiporter activity	Slc25a4	IDA		Mouse	MGI:MGI:6384889\|PMID:31341297
Molecular Function	GO:0005471	ATP:ADP antiporter activity	Slc25a4	IMP		Mouse	MGI:MGI:6407583\|PMID:31618756
Molecular Function	GO:0019899	enzyme binding	Slc25a4	IPI	RGD:1303174	Rat	PMID:12077116\|RGD:625503
Molecular Function	GO:0017077	oxidative phosphorylation uncoupler activity	Slc25a4	IDA		Mouse	MGI:MGI:6384889\|PMID:31341297
Molecular Function	GO:0005515	protein binding	SLC25A4	IPI	UniProtKB:Q08752	Human	PMID:16507998
Molecular Function	GO:0005515	protein binding	SLC25A4	IPI	UniProtKB:Q5S007	Human	PMID:21370995
Molecular Function	GO:0005515	protein binding	SLC25A4	IPI	UniProtKB:P22736-1	Human	PMID:24316735
Molecular Function	GO:0005515	protein binding	SLC25A4	IPI	UniProtKB:Q5S007	Human	PMID:24725412
Molecular Function	GO:0005515	protein binding	SLC25A4	IPI	UniProtKB:Q3KRB8	Human	PMID:31883789
Molecular Function	GO:0005515	protein binding	Slc25a4	IPI	UniProtKB:O35857	Mouse	MGI:MGI:6407583\|PMID:31618756
Molecular Function	GO:0005515	protein binding	Slc25a4	IPI	UniProtKB:Q9D385	Mouse	MGI:MGI:4887345\|PMID:11809823
Molecular Function	GO:0005515	protein binding	Slc25a4	IPI	RGD:628670	Rat	PMID:9820802\|RGD:2304024
Molecular Function	GO:0015078	proton transmembrane transporter activity	Slc25a4	IDA		Mouse	MGI:MGI:6384889\|PMID:31341297
Cellular Component	GO:0016020	membrane	SLC25A4	IDA		Human	PMID:27641616
Cellular Component	GO:0045121	membrane raft	Slc25a4	IDA		Rat	PMID:14499952\|RGD:12793007
Cellular Component	GO:0005743	mitochondrial inner membrane	SLC25A4	IDA		Human	PMID:21586654
Cellular Component	GO:0005743	mitochondrial inner membrane	Slc25a4	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005743	mitochondrial inner membrane	Slc25a4	IDA		Rat	PMID:18385140\|RGD:7241011
Cellular Component	GO:0005743	mitochondrial inner membrane	Slc25a4	IDA		Rat	PMID:9820802\|RGD:2304024
Cellular Component	GO:0005741	mitochondrial outer membrane	Slc25a4	IDA		Rat	PMID:18385140\|RGD:7241011
Cellular Component	GO:0005757	mitochondrial permeability transition pore complex	Slc25a4	IMP		Mouse	MGI:MGI:6414748\|PMID:31489369
Cellular Component	GO:0005739	mitochondrion	SLC25A4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	SLC25A4	HDA		Human	PMID:20833797
Cellular Component	GO:0005739	mitochondrion	Slc25a4	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Slc25a4	IDA		Rat	PMID:12821666\|RGD:1580617
Cellular Component	GO:0043209	myelin sheath	Slc25a4	HDA		Mouse	MGI:MGI:3834050\|PMID:17634366
Biological Process	GO:1990845	adaptive thermogenesis	Slc25a4	IMP		Mouse	MGI:MGI:6384889\|PMID:31341297
Biological Process	GO:0015866	ADP transport	SLC25A4	IMP		Human	PMID:27693233
Biological Process	GO:0007568	aging	Slc25a4	IEP		Rat	PMID:16187210\|RGD:9681471
Biological Process	GO:0008637	apoptotic mitochondrial changes	Slc25a4	IGI	MGI:MGI:1315197	Mouse	PMID:18350175
Biological Process	GO:0008637	apoptotic mitochondrial changes	Slc25a4	IGI	MGI:MGI:2145814	Mouse	PMID:18350175
Biological Process	GO:0007507	heart development	Slc25a4	IEP		Rat	PMID:12676547\|RGD:9681465
Biological Process	GO:0001889	liver development	Slc25a4	IEP		Rat	PMID:9468308\|RGD:9681468
Biological Process	GO:0140021	mitochondrial ADP transmembrane transport	SLC25A4	IDA		Human	PMID:21586654
Biological Process	GO:0140021	mitochondrial ADP transmembrane transport	Slc25a4	IDA		Mouse	MGI:MGI:6384889\|PMID:31341297
Biological Process	GO:0140021	mitochondrial ADP transmembrane transport	Slc25a4	IMP		Mouse	MGI:MGI:6407583\|PMID:31618756
Biological Process	GO:1990544	mitochondrial ATP transmembrane transport	SLC25A4	IDA		Human	PMID:21586654
Biological Process	GO:1990544	mitochondrial ATP transmembrane transport	Slc25a4	IMP		Mouse	MGI:MGI:6407583\|PMID:31618756
Biological Process	GO:1990544	mitochondrial ATP transmembrane transport	Slc25a4	IDA		Mouse	MGI:MGI:6384889\|PMID:31341297
Biological Process	GO:0010667	negative regulation of cardiac muscle cell apoptotic process	Slc25a4	IDA		Rat	PMID:22564366\|RGD:9681467
Biological Process	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process	Slc25a4	IDA		Rat	PMID:22564366\|RGD:9681467
Biological Process	GO:0060546	negative regulation of necroptotic process	SLC25A4	IMP		Human	PMID:16507998
Biological Process	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	Slc25a4	IDA		Rat	PMID:21325829\|RGD:9681466
Biological Process	GO:1901526	positive regulation of mitophagy	Slc25a4	IDA		Mouse	MGI:MGI:6407583\|PMID:31618756
Biological Process	GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	Slc25a4	IMP		Rat	PMID:18251717\|RGD:7242053
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	Slc25a4	IMP		Mouse	MGI:MGI:6414748\|PMID:31489369
Biological Process	GO:0070555	response to interleukin-1	Slc25a4	IEP		Rat	PMID:15950780\|RGD:8694125

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.