Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Slc25a5

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SLC25A5
- Mouse genes Slc25a5
- Rat genes Slc25a5
- Zfish genes si:dkey-251i10.1,slc25a5
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc25a5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000295	adenine nucleotide transmembrane transporter activity	SLC25A5	IMP		Human	PMID:19116139
Molecular Function	GO:0005471	ATP:ADP antiporter activity	Slc25a5	IMP		Mouse	MGI:MGI:6407583\|PMID:31618756
Molecular Function	GO:0005471	ATP:ADP antiporter activity	Slc25a5	IDA		Mouse	MGI:MGI:6384889\|PMID:31341297
Molecular Function	GO:0017077	oxidative phosphorylation uncoupler activity	Slc25a5	IDA		Mouse	MGI:MGI:6384889\|PMID:31341297
Molecular Function	GO:0005515	protein binding	SLC25A5	IPI	UniProtKB:Q9Y6E7	Human	PMID:17715127
Molecular Function	GO:0005515	protein binding	SLC25A5	IPI	UniProtKB:Q99623	Human	PMID:19116139
Molecular Function	GO:0005515	protein binding	SLC25A5	IPI	UniProtKB:P21796	Human	PMID:19130895
Molecular Function	GO:0005515	protein binding	SLC25A5	IPI	UniProtKB:P27144	Human	PMID:19130895
Molecular Function	GO:0005515	protein binding	SLC25A5	IPI	UniProtKB:Q8N357	Human	PMID:19154410
Molecular Function	GO:0005515	protein binding	SLC25A5	IPI	UniProtKB:Q5S007	Human	PMID:21370995
Molecular Function	GO:0005515	protein binding	SLC25A5	IPI	UniProtKB:Q5S007	Human	PMID:24725412
Molecular Function	GO:0005515	protein binding	SLC25A5	IPI	UniProtKB:Q7Z695	Human	PMID:27499296
Molecular Function	GO:0005515	protein binding	SLC25A5	IPI	UniProtKB:Q3KRB8	Human	PMID:31883789
Molecular Function	GO:0005515	protein binding	Slc25a5	IPI	UniProtKB:O35857	Mouse	MGI:MGI:6407583\|PMID:31618756
Molecular Function	GO:0005515	protein binding	Slc25a5	IPI	RGD:628670	Rat	PMID:9820802\|RGD:2304024
Molecular Function	GO:0015078	proton transmembrane transporter activity	Slc25a5	IDA		Mouse	MGI:MGI:6384889\|PMID:31341297
Molecular Function	GO:0003723	RNA binding	SLC25A5	HDA		Human	PMID:22658674
Molecular Function	GO:0031625	ubiquitin protein ligase binding	SLC25A5	IPI	UniProtKB:O60260	Human	PMID:19725078
Cellular Component	GO:0016020	membrane	SLC25A5	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	SLC25A5	IDA		Human	PMID:27641616
Cellular Component	GO:0045121	membrane raft	Slc25a5	IDA		Rat	PMID:14499952\|RGD:12793007
Cellular Component	GO:0005743	mitochondrial inner membrane	Slc25a5	IDA		Mouse	PMID:28376086
Cellular Component	GO:0005743	mitochondrial inner membrane	Slc25a5	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005743	mitochondrial inner membrane	Slc25a5	IDA		Rat	PMID:9820802\|RGD:2304024
Cellular Component	GO:0042645	mitochondrial nucleoid	SLC25A5	IDA		Human	PMID:18063578
Cellular Component	GO:0005757	mitochondrial permeability transition pore complex	Slc25a5	IMP		Mouse	MGI:MGI:6414748\|PMID:31489369
Cellular Component	GO:0005739	mitochondrion	SLC25A5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	SLC25A5	HDA		Human	PMID:20833797
Cellular Component	GO:0005739	mitochondrion	Slc25a5	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Slc25a5	HDA		Mouse	PMID:14651853
Cellular Component	GO:0071817	MMXD complex	SLC25A5	IDA		Human	PMID:20797633
Cellular Component	GO:0043209	myelin sheath	Slc25a5	HDA		Mouse	MGI:MGI:3834050\|PMID:17634366
Cellular Component	GO:0005634	nucleus	SLC25A5	HDA		Human	PMID:21630459
Biological Process	GO:1990845	adaptive thermogenesis	Slc25a5	IMP		Mouse	MGI:MGI:6384889\|PMID:31341297
Biological Process	GO:0051503	adenine nucleotide transport	SLC25A5	IMP		Human	PMID:19116139
Biological Process	GO:0030183	B cell differentiation	Slc25a5	IMP		Mouse	MGI:MGI:5790407\|PMID:25613378
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Slc25a5	IEP		Mouse	PMID:20439489
Biological Process	GO:0030218	erythrocyte differentiation	Slc25a5	IMP		Mouse	MGI:MGI:5790407\|PMID:25613378
Biological Process	GO:0140021	mitochondrial ADP transmembrane transport	Slc25a5	IDA		Mouse	MGI:MGI:6384889\|PMID:31341297
Biological Process	GO:0140021	mitochondrial ADP transmembrane transport	Slc25a5	IMP		Mouse	MGI:MGI:6407583\|PMID:31618756
Biological Process	GO:1990544	mitochondrial ATP transmembrane transport	Slc25a5	IMP		Mouse	MGI:MGI:6407583\|PMID:31618756
Biological Process	GO:1990544	mitochondrial ATP transmembrane transport	Slc25a5	IDA		Mouse	MGI:MGI:6384889\|PMID:31341297
Biological Process	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	SLC25A5	IMP		Human	PMID:19154410
Biological Process	GO:0008284	positive regulation of cell population proliferation	SLC25A5	IMP		Human	PMID:19154410
Biological Process	GO:1901526	positive regulation of mitophagy	Slc25a5	IDA		Mouse	MGI:MGI:6407583\|PMID:31618756
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	Slc25a5	IMP		Mouse	MGI:MGI:6414748\|PMID:31489369

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.