Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Slc26a6

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SLC26A6
- Mouse genes Slc26a6
- Rat genes Slc26a6
- Zfish genes si:ch211-117c9.2,slc26a6,slc26a6l
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc26a6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015106	bicarbonate transmembrane transporter activity	Slc26a6	IDA		Mouse	MGI:MGI:2388251\|PMID:12217875
Molecular Function	GO:0015106	bicarbonate transmembrane transporter activity	Slc26a6	IDA		Mouse	MGI:MGI:2177039\|PMID:11842009
Molecular Function	GO:0015108	chloride transmembrane transporter activity	Slc26a6	IDA		Mouse	MGI:MGI:2388251\|PMID:12217875
Molecular Function	GO:0015108	chloride transmembrane transporter activity	Slc26a6	IDA		Mouse	MGI:MGI:2177039\|PMID:11842009
Molecular Function	GO:0015108	chloride transmembrane transporter activity	Slc26a6	IMP		Mouse	MGI:MGI:3603991\|PMID:16141316
Molecular Function	GO:0015108	chloride transmembrane transporter activity	Slc26a6	IDA		Mouse	MGI:MGI:5514332\|PMID:17151144
Molecular Function	GO:0015108	chloride transmembrane transporter activity	Slc26a6	IDA		Mouse	PMID:11459928
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	SLC26A6	IDA		Human	PMID:20501439
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	Slc26a6	IDA		Mouse	MGI:MGI:6862362\|PMID:23933580
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	Slc26a6	IMP		Mouse	MGI:MGI:5466469\|PMID:22895259
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	Slc26a6	IDA		Mouse	MGI:MGI:5514337\|PMID:12119287
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	Slc26a6	IDA		Mouse	MGI:MGI:3710441\|PMID:17170027
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	Slc26a6	IDA		Mouse	MGI:MGI:2177039\|PMID:11842009
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	Slc26a6	IMP		Mouse	MGI:MGI:6163762\|PMID:29530983
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	Slc26a6	IDA		Mouse	MGI:MGI:7434533\|PMID:16606687
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	Slc26a6	IMP		Mouse	MGI:MGI:7434534\|PMID:20969732
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	Slc26a6	IMP		Mouse	MGI:MGI:4442131\|PMID:20150244
Molecular Function	GO:0015562	efflux transmembrane transporter activity	Slc26a6	IDA		Mouse	MGI:MGI:2388251\|PMID:12217875
Molecular Function	GO:0015499	formate transmembrane transporter activity	Slc26a6	IDA		Mouse	MGI:MGI:2388251\|PMID:12217875
Molecular Function	GO:0015499	formate transmembrane transporter activity	Slc26a6	IDA		Mouse	MGI:MGI:5514332\|PMID:17151144
Molecular Function	GO:0015499	formate transmembrane transporter activity	Slc26a6	IDA		Mouse	PMID:11459928
Molecular Function	GO:0019531	oxalate transmembrane transporter activity	Slc26a6	IMP		Mouse	MGI:MGI:3603991\|PMID:16141316
Molecular Function	GO:0019531	oxalate transmembrane transporter activity	Slc26a6	IMP		Mouse	MGI:MGI:5516184\|PMID:22021714
Molecular Function	GO:0019531	oxalate transmembrane transporter activity	Slc26a6	IDA		Mouse	MGI:MGI:2388251\|PMID:12217875
Molecular Function	GO:0030165	PDZ domain binding	Slc26a6	IDA		Mouse	MGI:MGI:3603991\|PMID:16141316
Molecular Function	GO:0005515	protein binding	Slc26a6	IPI	UniProtKB:Q5T2W1\|UniProtKB:Q865P3	Mouse	MGI:MGI:3603991\|PMID:16141316
Molecular Function	GO:0005515	protein binding	Slc26a6	IPI	UniProtKB:Q80SW1	Mouse	MGI:MGI:5634882\|PMID:23542070
Molecular Function	GO:0005515	protein binding	Slc26a6	IPI	UniProtKB:P26361\|UniProtKB:P70441\|UniProtKB:Q9WVC8	Mouse	MGI:MGI:5429843\|PMID:21976599
Molecular Function	GO:0008510	sodium:bicarbonate symporter activity	slc26a6l	IMP	ZFIN:ZDB-MRPHLNO-091216-6	Zfish	PMID:19801433
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	SLC26A6	IDA		Human	PMID:15548529
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	SLC26A6	IMP		Human	PMID:20501439
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	SLC26A6	IDA		Human	PMID:27681177
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	Slc26a6	IMP		Mouse	MGI:MGI:5466469\|PMID:22895259
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	Slc26a6	IDA		Mouse	MGI:MGI:5514337\|PMID:12119287
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	Slc26a6	IMP		Mouse	MGI:MGI:3621410\|PMID:16532010
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	Slc26a6	IDA		Mouse	MGI:MGI:5514332\|PMID:17151144
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	Slc26a6	IDA		Mouse	MGI:MGI:2388251\|PMID:12217875
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	Slc26a6	IMP		Mouse	MGI:MGI:4442131\|PMID:20150244
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	Slc26a6	IMP		Mouse	MGI:MGI:5516184\|PMID:22021714
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	Slc26a6	IDA		Mouse	MGI:MGI:2159729\|PMID:11459928
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	Slc26a6	IDA		Mouse	MGI:MGI:7434895\|PMID:15203903
Molecular Function	GO:0015116	sulfate transmembrane transporter activity	Slc26a6	IDA		Mouse	MGI:MGI:2388251\|PMID:12217875
Cellular Component	GO:0016324	apical plasma membrane	SLC26A6	IDA		Human	PMID:11087667
Cellular Component	GO:0016324	apical plasma membrane	SLC26A6	IDA		Human	PMID:20501439
Cellular Component	GO:0016324	apical plasma membrane	Slc26a6	IDA		Mouse	MGI:MGI:4360159\|PMID:18496516
Cellular Component	GO:0016324	apical plasma membrane	Slc26a6	IDA		Mouse	MGI:MGI:2159729\|PMID:11459928
Cellular Component	GO:0016324	apical plasma membrane	Slc26a6	IDA		Mouse	MGI:MGI:6163762\|PMID:29530983
Cellular Component	GO:0016324	apical plasma membrane	Slc26a6	IDA		Mouse	MGI:MGI:3603991\|PMID:16141316
Cellular Component	GO:0016324	apical plasma membrane	Slc26a6	IDA		Mouse	MGI:MGI:2177039\|PMID:11842009
Cellular Component	GO:0016324	apical plasma membrane	Slc26a6	IDA		Mouse	MGI:MGI:3710441\|PMID:17170027
Cellular Component	GO:0016324	apical plasma membrane	Slc26a6	IDA		Rat	PMID:23869188\|RGD:155226878
Cellular Component	GO:0016323	basolateral plasma membrane	SLC26A6	IDA		Human	PMID:11087667
Cellular Component	GO:0031526	brush border membrane	SLC26A6	IDA		Human	PMID:11087667
Cellular Component	GO:0031526	brush border membrane	Slc26a6	IDA		Mouse	MGI:MGI:3603991\|PMID:16141316
Cellular Component	GO:0031526	brush border membrane	Slc26a6	IDA		Mouse	MGI:MGI:2177039\|PMID:11842009
Cellular Component	GO:0031526	brush border membrane	Slc26a6	IDA		Mouse	MGI:MGI:2159729\|PMID:11459928
Cellular Component	GO:0031526	brush border membrane	Slc26a6	IDA		Mouse	MGI:MGI:3621410\|PMID:16532010
Cellular Component	GO:0005829	cytosol	SLC26A6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	SLC26A6	IDA		Human	PMID:11087667
Cellular Component	GO:0016020	membrane	Slc26a6	IDA		Mouse	MGI:MGI:5429843\|PMID:21976599
Cellular Component	GO:0016020	membrane	Slc26a6	IDA		Mouse	PMID:11842009
Cellular Component	GO:0005886	plasma membrane	SLC26A6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	SLC26A6	IDA		Human	PMID:27681177
Cellular Component	GO:0005886	plasma membrane	Slc26a6	IDA		Mouse	MGI:MGI:5514332\|PMID:17151144
Cellular Component	GO:0005886	plasma membrane	Slc26a6	IDA		Mouse	MGI:MGI:6862362\|PMID:23933580
Cellular Component	GO:0005886	plasma membrane	Slc26a6	IDA		Mouse	PMID:11459928
Cellular Component	GO:0097225	sperm midpiece	Slc26a6	IDA		Mouse	MGI:MGI:5429843\|PMID:21976599
Cellular Component	GO:0031982	vesicle	Slc26a6	IDA		Mouse	MGI:MGI:2177039\|PMID:11842009
Cellular Component	GO:0012506	vesicle membrane	Slc26a6	IDA		Mouse	MGI:MGI:3603991\|PMID:16141316
Cellular Component	GO:0012506	vesicle membrane	Slc26a6	IDA		Mouse	MGI:MGI:3621410\|PMID:16532010
Biological Process	GO:0015701	bicarbonate transport	SLC26A6	IMP		Human	PMID:20501439
Biological Process	GO:0015701	bicarbonate transport	Slc26a6	IMP		Mouse	MGI:MGI:5466469\|PMID:22895259
Biological Process	GO:0015701	bicarbonate transport	Slc26a6	IDA		Mouse	MGI:MGI:2388251\|PMID:12217875
Biological Process	GO:0015701	bicarbonate transport	Slc26a6	IDA		Mouse	MGI:MGI:5514337\|PMID:12119287
Biological Process	GO:0015701	bicarbonate transport	Slc26a6	IMP		Mouse	MGI:MGI:4442131\|PMID:20150244
Biological Process	GO:0015701	bicarbonate transport	Slc26a6	IMP	MGI:MGI:3831563	Mouse	PMID:19033647
Biological Process	GO:0015701	bicarbonate transport	Slc26a6	IDA		Mouse	PMID:11842009
Biological Process	GO:0015701	bicarbonate transport	slc26a6l	IMP	ZFIN:ZDB-MRPHLNO-091216-6	Zfish	PMID:19801433\|ZFIN:ZDB-PUB-091023-17
Biological Process	GO:0071320	cellular response to cAMP	Slc26a6	IDA		Mouse	MGI:MGI:5466469\|PMID:22895259
Biological Process	GO:0071332	cellular response to fructose stimulus	Slc26a6	IDA		Mouse	MGI:MGI:4360159\|PMID:18496516
Biological Process	GO:0071346	cellular response to type II interferon	SLC26A6	IDA		Human	PMID:18655181
Biological Process	GO:0006821	chloride transport	SLC26A6	IMP		Human	PMID:20501439
Biological Process	GO:0006821	chloride transport	Slc26a6	IMP		Mouse	MGI:MGI:4442131\|PMID:20150244
Biological Process	GO:0006821	chloride transport	Slc26a6	IDA		Mouse	MGI:MGI:2388251\|PMID:12217875
Biological Process	GO:0006821	chloride transport	Slc26a6	IMP		Mouse	MGI:MGI:3621410\|PMID:16532010
Biological Process	GO:0006821	chloride transport	Slc26a6	IMP		Mouse	MGI:MGI:3603991\|PMID:16141316
Biological Process	GO:0006821	chloride transport	Slc26a6	IMP		Mouse	MGI:MGI:5466469\|PMID:22895259
Biological Process	GO:0006821	chloride transport	Slc26a6	IDA		Mouse	MGI:MGI:5514337\|PMID:12119287
Biological Process	GO:0006821	chloride transport	Slc26a6	IDA		Mouse	MGI:MGI:5514332\|PMID:17151144
Biological Process	GO:0006821	chloride transport	Slc26a6	IDA		Mouse	PMID:11842009
Biological Process	GO:0006821	chloride transport	Slc26a6	IDA		Mouse	PMID:11459928
Biological Process	GO:0006821	chloride transport	slc26a6l	IMP	ZFIN:ZDB-MRPHLNO-091216-6	Zfish	PMID:19801433
Biological Process	GO:0042045	epithelial fluid transport	Slc26a6	IMP		Mouse	MGI:MGI:4360159\|PMID:18496516
Biological Process	GO:0051649	establishment of localization in cell	Slc26a6	IMP	MGI:MGI:3831563	Mouse	PMID:19033647
Biological Process	GO:0044849	estrous cycle	Slc26a6	IEP		Rat	PMID:23869188\|RGD:155226878
Biological Process	GO:0015724	formate transport	Slc26a6	IMP		Mouse	MGI:MGI:5466469\|PMID:22895259
Biological Process	GO:0015724	formate transport	Slc26a6	IDA		Mouse	MGI:MGI:2388251\|PMID:12217875
Biological Process	GO:0015724	formate transport	Slc26a6	IDA		Mouse	MGI:MGI:5514337\|PMID:12119287
Biological Process	GO:0015724	formate transport	Slc26a6	IDA		Mouse	MGI:MGI:5514332\|PMID:17151144
Biological Process	GO:0015724	formate transport	Slc26a6	IDA		Mouse	PMID:11459928
Biological Process	GO:0050892	intestinal absorption	Slc26a6	IMP		Mouse	MGI:MGI:5516184\|PMID:22021714
Biological Process	GO:0051454	intracellular pH elevation	Slc26a6	IMP		Mouse	MGI:MGI:5429843\|PMID:21976599
Biological Process	GO:0015797	mannitol transmembrane transport	Slc26a6	IMP		Mouse	MGI:MGI:5516184\|PMID:22021714
Biological Process	GO:0055081	monoatomic anion homeostasis	slc26a6	IDA		Zfish	PMID:19641131
Biological Process	GO:0019532	oxalate transport	SLC26A6	IMP		Human	PMID:20501439
Biological Process	GO:0019532	oxalate transport	Slc26a6	IMP		Mouse	MGI:MGI:3621410\|PMID:16532010
Biological Process	GO:0019532	oxalate transport	Slc26a6	IDA		Mouse	MGI:MGI:5514337\|PMID:12119287
Biological Process	GO:0019532	oxalate transport	Slc26a6	IDA		Mouse	MGI:MGI:2388251\|PMID:12217875
Biological Process	GO:0019532	oxalate transport	Slc26a6	IMP		Mouse	MGI:MGI:5516184\|PMID:22021714
Biological Process	GO:0019532	oxalate transport	Slc26a6	IMP		Mouse	MGI:MGI:3603991\|PMID:16141316
Biological Process	GO:0046724	oxalic acid secretion	Slc26a6	IMP		Mouse	MGI:MGI:5516184\|PMID:22021714
Biological Process	GO:2001150	positive regulation of dipeptide transmembrane transport	Slc26a6	IMP		Mouse	MGI:MGI:4442131\|PMID:20150244
Biological Process	GO:0070528	protein kinase C signaling	Slc26a6	IDA		Mouse	MGI:MGI:5514332\|PMID:17151144
Biological Process	GO:0051453	regulation of intracellular pH	SLC26A6	IMP		Human	PMID:20501439
Biological Process	GO:0051453	regulation of intracellular pH	Slc26a6	IMP		Mouse	MGI:MGI:4442131\|PMID:20150244
Biological Process	GO:0009651	response to salt stress	slc26a6	IDA		Zfish	PMID:19641131
Biological Process	GO:0035725	sodium ion transmembrane transport	slc26a6l	IMP	ZFIN:ZDB-MRPHLNO-091216-6	Zfish	PMID:19801433\|ZFIN:ZDB-PUB-091023-17
Biological Process	GO:0048240	sperm capacitation	Slc26a6	IMP		Mouse	MGI:MGI:5429843\|PMID:21976599
Biological Process	GO:0008272	sulfate transport	SLC26A6	IMP		Human	PMID:20501439
Biological Process	GO:0008272	sulfate transport	Slc26a6	IDA		Mouse	MGI:MGI:5514337\|PMID:12119287
Biological Process	GO:0008272	sulfate transport	Slc26a6	IMP		Mouse	MGI:MGI:3621410\|PMID:16532010
Biological Process	GO:0008272	sulfate transport	Slc26a6	IDA		Mouse	MGI:MGI:2388251\|PMID:12217875
Biological Process	GO:0030321	transepithelial chloride transport	SLC26A6	IMP		Human	PMID:20501439
Biological Process	GO:0030321	transepithelial chloride transport	Slc26a6	IMP		Mouse	MGI:MGI:5466469\|PMID:22895259
Biological Process	GO:0030321	transepithelial chloride transport	Slc26a6	IDA		Mouse	MGI:MGI:2159729\|PMID:11459928
Biological Process	GO:0070633	transepithelial transport	Slc26a6	IMP		Mouse	MGI:MGI:3621410\|PMID:16532010
Biological Process	GO:0070633	transepithelial transport	Slc26a6	IMP		Mouse	MGI:MGI:4442131\|PMID:20150244
Biological Process	GO:0070633	transepithelial transport	Slc26a6	IMP		Mouse	MGI:MGI:3603991\|PMID:16141316
Biological Process	GO:0070633	transepithelial transport	Slc26a6	IMP		Mouse	MGI:MGI:5516184\|PMID:22021714

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/09/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.