Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC27A1
  • Mouse genes Slc27a1
  • Rat genes Slc27a1
  • Zfish genes slc27a1a,slc27a1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc27a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015225	biotin transmembrane transporter activity	SLC27A1	IDA		Human	PMID:28035674
Molecular Function	GO:0015562	efflux transmembrane transporter activity	SLC27A1	IDA		Human	PMID:28035674
Molecular Function	GO:0015562	efflux transmembrane transporter activity	SLC27A1	IMP		Human	PMID:31091338
Molecular Function	GO:0015245	fatty acid transmembrane transporter activity	Slc27a1	IDA		Mouse	MGI:MGI:69386|PMID:7954810
Molecular Function	GO:0015245	fatty acid transmembrane transporter activity	Slc27a1	IDA		Mouse	PMID:12533547
Molecular Function	GO:0015245	fatty acid transmembrane transporter activity	Slc27a1	IGI	SGD:S000000245	Mouse	PMID:18258213
Molecular Function	GO:0015245	fatty acid transmembrane transporter activity	Slc27a1	IGI	SGD:S000005844	Mouse	PMID:18258213
Molecular Function	GO:0015245	fatty acid transmembrane transporter activity	Slc27a1	IDA		Mouse	PMID:9671728
Molecular Function	GO:0042802	identical protein binding	Slc27a1	IPI	PR:Q60714	Mouse	PMID:12566451
Molecular Function	GO:0005324	long-chain fatty acid transporter activity	SLC27A1	IMP		Human	PMID:21395585
Molecular Function	GO:0005324	long-chain fatty acid transporter activity	SLC27A1	IDA		Human	PMID:28035674
Molecular Function	GO:0005324	long-chain fatty acid transporter activity	SLC27A1	IMP		Human	PMID:28035674
Molecular Function	GO:0005324	long-chain fatty acid transporter activity	SLC27A1	IMP		Human	PMID:31091338
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	Slc27a1	IDA		Mouse	MGI:MGI:6154651|PMID:12235169
Molecular Function	GO:0090434	oleoyl-CoA ligase activity	Slc27a1	IMP		Mouse	MGI:MGI:6232786|PMID:23024797
Molecular Function	GO:0005515	protein binding	SLC27A1	IPI	UniProtKB:P07814	Human	PMID:28178239
Molecular Function	GO:0005515	protein binding	SLC27A1	IPI	UniProtKB:Q96PD7	Human	PMID:30970241
Molecular Function	GO:0005515	protein binding	Slc27a1	IPI	UniProtKB:Q8CGC7	Mouse	MGI:MGI:5913528|PMID:28178239
Molecular Function	GO:0005515	protein binding	Slc27a1	IPI	RGD:2396	Rat	PMID:19429947|RGD:2312787
Molecular Function	GO:0005515	protein binding	Slc27a1	IPI	RGD:2397	Rat	PMID:19429947|RGD:2312787
Molecular Function	GO:0031957	very long-chain fatty acid-CoA ligase activity	Slc27a1	IMP		Mouse	MGI:MGI:6154654|PMID:10593920
Molecular Function	GO:0031957	very long-chain fatty acid-CoA ligase activity	Slc27a1	IDA		Mouse	PMID:18258213
Cellular Component	GO:0009925	basal plasma membrane	Slc27a1	IDA		Mouse	MGI:MGI:6414733|PMID:28035674
Cellular Component	GO:0005901	caveola	Slc27a1	IDA		Rat	PMID:16803459|RGD:1642797
Cellular Component	GO:0005783	endoplasmic reticulum	Slc27a1	IMP		Mouse	MGI:MGI:6232786|PMID:23024797
Cellular Component	GO:0005783	endoplasmic reticulum	Slc27a1	IDA		Mouse	PMID:15496455
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Slc27a1	IDA		Rat	PMID:15848183|RGD:1600648
Cellular Component	GO:0016020	membrane	SLC27A1	HDA		Human	PMID:19946888
Cellular Component	GO:0005743	mitochondrial inner membrane	Slc27a1	IDA		Rat	PMID:19429947|RGD:2312787
Cellular Component	GO:0005739	mitochondrion	Slc27a1	IDA		Rat	PMID:19429947|RGD:2312787
Cellular Component	GO:0005886	plasma membrane	SLC27A1	IDA		Human	PMID:28035674
Cellular Component	GO:0005886	plasma membrane	SLC27A1	IDA		Human	PMID:31091338
Cellular Component	GO:0005886	plasma membrane	Slc27a1	IDA		Mouse	MGI:MGI:69386|PMID:7954810
Cellular Component	GO:0005886	plasma membrane	Slc27a1	IDA		Mouse	MGI:MGI:5913528|PMID:28178239
Cellular Component	GO:0005886	plasma membrane	Slc27a1	IDA		Mouse	PMID:15496455
Cellular Component	GO:0005886	plasma membrane	Slc27a1	IDA		Mouse	PMID:17130465
Cellular Component	GO:0005886	plasma membrane	Slc27a1	IDA		Rat	PMID:15848183|RGD:1600648
Biological Process	GO:0033211	adiponectin-activated signaling pathway	Slc27a1	IMP		Mouse	PMID:20667975
Biological Process	GO:1905135	biotin import across plasma membrane	SLC27A1	IDA		Human	PMID:28035674
Biological Process	GO:0015878	biotin transport	SLC27A1	IDA		Human	PMID:28035674
Biological Process	GO:1905039	carboxylic acid transmembrane transport	Slc27a1	IGI	SGD:S000005844	Mouse	MGI:MGI:3778715|PMID:18258213
Biological Process	GO:0032049	cardiolipin biosynthetic process	SLC27A1	IMP		Human	PMID:19523918
Biological Process	GO:0140115	export across plasma membrane	SLC27A1	IDA		Human	PMID:28035674
Biological Process	GO:0140115	export across plasma membrane	SLC27A1	IMP		Human	PMID:31091338
Biological Process	GO:0015908	fatty acid transport	Slc27a1	IGI	SGD:S000005844	Mouse	MGI:MGI:3778715|PMID:18258213
Biological Process	GO:0015908	fatty acid transport	Slc27a1	IMP	MGI:MGI:3038701	Mouse	PMID:17130465
Biological Process	GO:0015908	fatty acid transport	Slc27a1	IDA		Mouse	PMID:12533547
Biological Process	GO:0015908	fatty acid transport	Slc27a1	IDA		Mouse	PMID:9671728
Biological Process	GO:0044381	glucose import in response to insulin stimulus	Slc27a1	IMP		Mouse	MGI:MGI:6232786|PMID:23024797
Biological Process	GO:1990379	lipid transport across blood-brain barrier	SLC27A1	IMP		Human	PMID:21395585
Biological Process	GO:0015911	long-chain fatty acid import across plasma membrane	SLC27A1	IDA		Human	PMID:28035674
Biological Process	GO:0015911	long-chain fatty acid import across plasma membrane	SLC27A1	IMP		Human	PMID:28035674
Biological Process	GO:0044539	long-chain fatty acid import into cell	SLC27A1	IMP		Human	PMID:28178239
Biological Process	GO:0044539	long-chain fatty acid import into cell	Slc27a1	IDA		Mouse	MGI:MGI:6154651|PMID:12235169
Biological Process	GO:0044539	long-chain fatty acid import into cell	Slc27a1	IMP		Mouse	MGI:MGI:6232786|PMID:23024797
Biological Process	GO:0044539	long-chain fatty acid import into cell	Slc27a1	IDA		Mouse	MGI:MGI:69386|PMID:7954810
Biological Process	GO:0015909	long-chain fatty acid transport	SLC27A1	IMP		Human	PMID:21395585
Biological Process	GO:0015909	long-chain fatty acid transport	SLC27A1	IDA		Human	PMID:28035674
Biological Process	GO:0015909	long-chain fatty acid transport	SLC27A1	IMP		Human	PMID:31091338
Biological Process	GO:0015909	long-chain fatty acid transport	Slc27a1	IMP	MGI:MGI:3038701	Mouse	PMID:16611988
Biological Process	GO:0001579	medium-chain fatty acid transport	Slc27a1	IGI	SGD:S000000245	Mouse	PMID:18258213
Biological Process	GO:0001579	medium-chain fatty acid transport	Slc27a1	IGI	SGD:S000005844	Mouse	PMID:18258213
Biological Process	GO:0071072	negative regulation of phospholipid biosynthetic process	SLC27A1	IMP		Human	PMID:19523918
Biological Process	GO:0006654	phosphatidic acid biosynthetic process	SLC27A1	IMP		Human	PMID:19523918
Biological Process	GO:0006656	phosphatidylcholine biosynthetic process	SLC27A1	IMP		Human	PMID:19523918
Biological Process	GO:0006646	phosphatidylethanolamine biosynthetic process	SLC27A1	IMP		Human	PMID:19523918
Biological Process	GO:0006655	phosphatidylglycerol biosynthetic process	SLC27A1	IMP		Human	PMID:19523918
Biological Process	GO:0006661	phosphatidylinositol biosynthetic process	SLC27A1	IMP		Human	PMID:19523918
Biological Process	GO:0006659	phosphatidylserine biosynthetic process	SLC27A1	IMP		Human	PMID:19523918
Biological Process	GO:0031652	positive regulation of heat generation	Slc27a1	IMP	MGI:MGI:3038701	Mouse	PMID:17130465
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	Slc27a1	IMP		Mouse	PMID:19560442
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	Slc27a1	IMP		Mouse	PMID:20667975
Biological Process	GO:0010867	positive regulation of triglyceride biosynthetic process	Slc27a1	IDA		Mouse	MGI:MGI:6154651|PMID:12235169
Biological Process	GO:0009409	response to cold	Slc27a1	IMP	MGI:MGI:3038701	Mouse	PMID:17130465
Biological Process	GO:0032868	response to insulin	Slc27a1	IMP	MGI:MGI:3038701	Mouse	PMID:14991074

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern