Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC27A4
  • Mouse genes Slc27a4
  • Rat genes Slc27a4
  • Zfish genes slc27a4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc27a4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005324	long-chain fatty acid transporter activity	SLC27A4	IMP		Human	PMID:21395585
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	SLC27A4	IDA		Human	PMID:22022213
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	Slc27a4	IDA		Mouse	PMID:11404000
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	Slc27a4	IDA		Mouse	PMID:15653672
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	Slc27a4	IDA		Mouse	PMID:17062637
Molecular Function	GO:0090434	oleoyl-CoA ligase activity	SLC27A4	IDA		Human	PMID:25603556
Molecular Function	GO:0090434	oleoyl-CoA ligase activity	Slc27a4	IMP		Mouse	MGI:MGI:6232786|PMID:23024797
Molecular Function	GO:0090434	oleoyl-CoA ligase activity	Slc27a4	IDA		Mouse	MGI:MGI:5314874|PMID:21750264
Molecular Function	GO:0090433	palmitoyl-CoA ligase activity	SLC27A4	IDA		Human	PMID:25603556
Molecular Function	GO:0031957	very long-chain fatty acid-CoA ligase activity	Slc27a4	IMP	MGI:MGI:2667328	Mouse	PMID:15653672
Molecular Function	GO:0031957	very long-chain fatty acid-CoA ligase activity	Slc27a4	IDA		Mouse	PMID:18258213
Molecular Function	GO:0031957	very long-chain fatty acid-CoA ligase activity	Slc27a4	IDA		Mouse	PMID:15653672
Molecular Function	GO:0031957	very long-chain fatty acid-CoA ligase activity	Slc27a4	IDA		Mouse	PMID:17522045
Cellular Component	GO:0031526	brush border membrane	Slc27a4	IDA		Mouse	PMID:14512415
Cellular Component	GO:0005783	endoplasmic reticulum	SLC27A4	IDA		Human	PMID:32521232
Cellular Component	GO:0005783	endoplasmic reticulum	Slc27a4	IMP		Mouse	MGI:MGI:6232786|PMID:23024797
Cellular Component	GO:0005783	endoplasmic reticulum	Slc27a4	IDA		Mouse	MGI:MGI:5314874|PMID:21750264
Cellular Component	GO:0005783	endoplasmic reticulum	Slc27a4	IDA		Mouse	PMID:17062637
Cellular Component	GO:0005783	endoplasmic reticulum	Slc27a4	IDA		Mouse	PMID:15496455
Cellular Component	GO:0005789	endoplasmic reticulum membrane	SLC27A4	IDA		Human	PMID:22022213
Cellular Component	GO:0005789	endoplasmic reticulum membrane	SLC27A4	IDA		Human	PMID:25603556
Cellular Component	GO:0016020	membrane	SLC27A4	HDA		Human	PMID:19946888
Cellular Component	GO:0005902	microvillus	Slc27a4	IDA		Mouse	PMID:10518211
Cellular Component	GO:0005886	plasma membrane	Slc27a4	IDA		Mouse	PMID:15496455
Biological Process	GO:0090630	activation of GTPase activity	SLC27A4	IDA		Human	PMID:25603556
Biological Process	GO:0051649	establishment of localization in cell	Slc27a4	IMP		Mouse	PMID:10518211
Biological Process	GO:0051649	establishment of localization in cell	Slc27a4	IMP	MGI:MGI:2684501	Mouse	PMID:14512415
Biological Process	GO:0006631	fatty acid metabolic process	SLC27A4	IDA		Human	PMID:25603556
Biological Process	GO:0006631	fatty acid metabolic process	Slc27a4	IMP	MGI:MGI:2445864	Mouse	PMID:18843142
Biological Process	GO:0015908	fatty acid transport	SLC27A4	IMP		Human	PMID:32521232
Biological Process	GO:0044381	glucose import in response to insulin stimulus	Slc27a4	IMP		Mouse	MGI:MGI:6232786|PMID:23024797
Biological Process	GO:1990379	lipid transport across blood-brain barrier	SLC27A4	IMP		Human	PMID:21395585
Biological Process	GO:0044539	long-chain fatty acid import into cell	SLC27A4	IDA		Human	PMID:22022213
Biological Process	GO:0044539	long-chain fatty acid import into cell	Slc27a4	IDA		Mouse	MGI:MGI:5703705|PMID:24503477
Biological Process	GO:0044539	long-chain fatty acid import into cell	Slc27a4	IDA		Mouse	MGI:MGI:5314874|PMID:21750264
Biological Process	GO:0044539	long-chain fatty acid import into cell	Slc27a4	IMP		Mouse	MGI:MGI:6232786|PMID:23024797
Biological Process	GO:0001676	long-chain fatty acid metabolic process	SLC27A4	IDA		Human	PMID:22022213
Biological Process	GO:0001676	long-chain fatty acid metabolic process	Slc27a4	IDA		Mouse	PMID:15653672
Biological Process	GO:0001676	long-chain fatty acid metabolic process	Slc27a4	IDA		Mouse	PMID:11404000
Biological Process	GO:0015909	long-chain fatty acid transport	SLC27A4	IMP		Human	PMID:21395585
Biological Process	GO:0015909	long-chain fatty acid transport	Slc27a4	IMP		Mouse	PMID:10518211
Biological Process	GO:0015909	long-chain fatty acid transport	Slc27a4	IMP	MGI:MGI:2684501	Mouse	PMID:14512415
Biological Process	GO:0001579	medium-chain fatty acid transport	Slc27a4	IGI	SGD:S000005844	Mouse	PMID:18258213
Biological Process	GO:0001579	medium-chain fatty acid transport	Slc27a4	IGI	SGD:S000000245	Mouse	PMID:18258213
Biological Process	GO:0001579	medium-chain fatty acid transport	Slc27a4	IDA		Mouse	PMID:17062637
Biological Process	GO:0062003	negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity	Slc27a4	IDA		Mouse	MGI:MGI:5471874|PMID:23407971
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	SLC27A4	IDA		Human	PMID:25603556
Biological Process	GO:0043065	positive regulation of apoptotic process	SLC27A4	IDA		Human	PMID:25603556
Biological Process	GO:0007584	response to nutrient	Slc27a4	IEP		Rat	PMID:17638014|RGD:2312797
Biological Process	GO:0043588	skin development	Slc27a4	IMP	MGI:MGI:2445864	Mouse	PMID:17401141
Biological Process	GO:0043588	skin development	Slc27a4	IMP	MGI:MGI:2177426,MGI:MGI:2667329	Mouse	PMID:16354193
Biological Process	GO:0043588	skin development	Slc27a4	IMP	MGI:MGI:2667328	Mouse	PMID:12821645
Biological Process	GO:0042760	very long-chain fatty acid catabolic process	Slc27a4	IDA		Mouse	PMID:17522045
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	Slc27a4	IMP	MGI:MGI:2445864	Mouse	PMID:17401141
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	Slc27a4	IDA		Mouse	PMID:15653672
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	Slc27a4	IDA		Mouse	PMID:17522045

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern