Comparative GO Graph (mouse, human, rat)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Slc2a4

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SLC2A4
- Mouse genes Slc2a4
- Rat genes Slc2a4
- Zfish genes
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc2a4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0055056	D-glucose transmembrane transporter activity	Slc2a4	IDA		Rat	PMID:1733237\|RGD:2306212
Molecular Function	GO:0055056	D-glucose transmembrane transporter activity	Slc2a4	IDA		Rat	PMID:2211693\|RGD:2303167
Molecular Function	GO:0005355	glucose transmembrane transporter activity	SLC2A4	IDA		Human	PMID:25004245
Molecular Function	GO:0005355	glucose transmembrane transporter activity	Slc2a4	IDA		Mouse	PMID:12097321
Molecular Function	GO:0005355	glucose transmembrane transporter activity	Slc2a4	IDA		Rat	PMID:11500317\|RGD:631237
Molecular Function	GO:0005355	glucose transmembrane transporter activity	Slc2a4	IDA		Rat	PMID:2211693\|RGD:2303167
Molecular Function	GO:0005355	glucose transmembrane transporter activity	Slc2a4	IDA		Rat	PMID:2645527\|RGD:14402447
Molecular Function	GO:0005355	glucose transmembrane transporter activity	Slc2a4	IDA		Rat	PMID:2649253\|RGD:729967
Molecular Function	GO:0005355	glucose transmembrane transporter activity	Slc2a4	IMP		Rat	PMID:9059504\|RGD:730188
Molecular Function	GO:0015304	glucose uniporter activity	Slc2a4	IDA		Rat	PMID:12417639\|RGD:628346
Molecular Function	GO:0005515	protein binding	SLC2A4	IPI	UniProtKB:P53675	Human	PMID:19478182
Molecular Function	GO:0005515	protein binding	SLC2A4	IPI	UniProtKB:Q00610	Human	PMID:19478182
Molecular Function	GO:0005515	protein binding	SLC2A4	IPI	UniProtKB:O43889-2	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	Slc2a4	IPI	UniProtKB:Q3U7R1	Mouse	MGI:MGI:6093159\|PMID:19255425
Molecular Function	GO:0005515	protein binding	Slc2a4	IPI	PR:O70372	Mouse	PMID:24970747
Molecular Function	GO:0005515	protein binding	Slc2a4	IPI	PR:O08917	Mouse	PMID:16455755
Molecular Function	GO:0005515	protein binding	Slc2a4	IPI	PR:Q8BVI5	Mouse	PMID:26629404
Molecular Function	GO:0005515	protein binding	Slc2a4	IPI	PR:O55101	Mouse	PMID:26629404
Molecular Function	GO:0005515	protein binding	Slc2a4	IPI	PR:Q8C838	Mouse	PMID:26629404
Molecular Function	GO:0005515	protein binding	Slc2a4	IPI	PR:P63024	Mouse	PMID:26629404
Molecular Function	GO:0005515	protein binding	Slc2a4	IPI	UniProtKB:P04797	Rat	PMID:16396496\|RGD:8553682
Molecular Function	GO:0005515	protein binding	Slc2a4	IPI	UniProtKB:Q9QXQ0	Rat	PMID:16396496\|RGD:8553682
Molecular Function	GO:0005515	protein binding	Slc2a4	IPI	RGD:2281	Rat	PMID:17277024\|RGD:1600213
Cellular Component	GO:0009986	cell surface	SLC2A4	IDA		Human	PMID:31112275
Cellular Component	GO:0009986	cell surface	Slc2a4	IDA		Rat	PMID:20868366\|RGD:7349316
Cellular Component	GO:0005905	clathrin-coated pit	Slc2a4	IDA		Rat	PMID:1881917\|RGD:2306204
Cellular Component	GO:0030136	clathrin-coated vesicle	SLC2A4	IDA		Human	PMID:19478182
Cellular Component	GO:0005737	cytoplasm	Slc2a4	IDA		Rat	PMID:20080987\|RGD:12903235
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	Slc2a4	IDA		Mouse	MGI:MGI:6162416\|PMID:26240143
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	Slc2a4	IDA		Mouse	PMID:12490950
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	Slc2a4	IDA		Mouse	PMID:26629404
Cellular Component	GO:0005829	cytosol	Slc2a4	IDA		Mouse	PMID:18511518
Cellular Component	GO:0005829	cytosol	Slc2a4	IDA		Rat	PMID:29676955\|RGD:13703029
Cellular Component	GO:0012505	endomembrane system	Slc2a4	IDA		Mouse	MGI:MGI:5292403\|PMID:21907143
Cellular Component	GO:0005768	endosome	Slc2a4	IDA		Mouse	PMID:15247266
Cellular Component	GO:0005768	endosome	Slc2a4	IDA		Rat	PMID:12450403\|RGD:727471
Cellular Component	GO:0009897	external side of plasma membrane	SLC2A4	IDA		Human	PMID:14562105
Cellular Component	GO:0070062	extracellular exosome	Slc2a4	IDA		Mouse	PMID:19724054
Cellular Component	GO:0032593	insulin-responsive compartment	SLC2A4	IDA		Human	PMID:19590752
Cellular Component	GO:0032593	insulin-responsive compartment	Slc2a4	IDA		Mouse	MGI:MGI:5292403\|PMID:21907143
Cellular Component	GO:0032593	insulin-responsive compartment	Slc2a4	IDA		Mouse	PMID:12490950
Cellular Component	GO:0032593	insulin-responsive compartment	Slc2a4	IDA		Mouse	PMID:18227281
Cellular Component	GO:0032593	insulin-responsive compartment	Slc2a4	IDA		Rat	PMID:8366094\|RGD:2306265
Cellular Component	GO:0032593	insulin-responsive compartment	Slc2a4	IDA		Rat	PMID:9271094\|RGD:2306434
Cellular Component	GO:0032593	insulin-responsive compartment	Slc2a4	IDA		Rat	PMID:9516411\|RGD:2306429
Cellular Component	GO:0032593	insulin-responsive compartment	Slc2a4	IDA		Rat	PMID:9880520\|RGD:2306430
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Slc2a4	IDA		Rat	PMID:10051443\|RGD:634161
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Slc2a4	IDA		Rat	PMID:8037667\|RGD:2304043
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Slc2a4	IDA		Rat	PMID:8366094\|RGD:2306265
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Slc2a4	IDA		Rat	PMID:8536622\|RGD:2306442
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Slc2a4	IDA		Rat	PMID:9224710\|RGD:2306433
Cellular Component	GO:0016020	membrane	Slc2a4	IDA		Mouse	PMID:16455755
Cellular Component	GO:0016020	membrane	Slc2a4	IDA		Mouse	PMID:23041416
Cellular Component	GO:0016020	membrane	Slc2a4	IDA		Mouse	PMID:14562105
Cellular Component	GO:0016020	membrane	Slc2a4	IDA		Rat	PMID:11500317\|RGD:631237
Cellular Component	GO:0045121	membrane raft	Slc2a4	IDA		Mouse	PMID:18511518
Cellular Component	GO:0005771	multivesicular body	Slc2a4	IDA		Rat	PMID:1881917\|RGD:2306204
Cellular Component	GO:0048471	perinuclear region of cytoplasm	SLC2A4	IDA		Human	PMID:12556481
Cellular Component	GO:0048471	perinuclear region of cytoplasm	SLC2A4	IDA		Human	PMID:14562105
Cellular Component	GO:0048471	perinuclear region of cytoplasm	SLC2A4	IDA		Human	PMID:19590752
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Slc2a4	IDA		Mouse	MGI:MGI:6162416\|PMID:26240143
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Slc2a4	IDA		Mouse	MGI:MGI:5807293\|PMID:27354378
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Slc2a4	IDA		Mouse	PMID:15800058
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Slc2a4	IDA		Mouse	PMID:26629404
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Slc2a4	IDA		Mouse	PMID:10444069
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Slc2a4	IDA		Rat	PMID:12388133\|RGD:2306288
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Slc2a4	IDA		Rat	PMID:20868366\|RGD:7349316
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Slc2a4	IDA		Rat	PMID:9271094\|RGD:2306434
Cellular Component	GO:0005886	plasma membrane	SLC2A4	IDA		Human	PMID:12556481
Cellular Component	GO:0005886	plasma membrane	SLC2A4	IDA		Human	PMID:19590752
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Mouse	MGI:MGI:6201900\|PMID:27739494
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Mouse	MGI:MGI:5292403\|PMID:21907143
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Mouse	MGI:MGI:6162416\|PMID:26240143
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Mouse	PMID:26629404
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Mouse	PMID:15247266
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Mouse	PMID:10394363
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Mouse	PMID:20582536
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Mouse	PMID:12832401
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Mouse	PMID:12490950
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Mouse	PMID:12297296
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Mouse	PMID:15800058
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Mouse	PMID:12917015
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Mouse	PMID:10444069
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Mouse	PMID:18511518
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Mouse	PMID:17003038
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Mouse	PMID:18343214
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Rat	PMID:10051443\|RGD:634161
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Rat	PMID:16870704\|RGD:2306291
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Rat	PMID:20080987\|RGD:12903235
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Rat	PMID:2211693\|RGD:2303167
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Rat	PMID:8037667\|RGD:2304043
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Rat	PMID:8536622\|RGD:2306442
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Rat	PMID:9224710\|RGD:2306433
Cellular Component	GO:0005886	plasma membrane	Slc2a4	IDA		Rat	PMID:27881773\|RGD:25671385
Cellular Component	GO:0098793	presynapse	Slc2a4	IDA		Rat	PMID:28111082\|RGD:13702195
Cellular Component	GO:0098793	presynapse	Slc2a4	IMP		Rat	PMID:28111082\|RGD:13702195
Cellular Component	GO:0042383	sarcolemma	Slc2a4	IDA		Mouse	PMID:16455755
Cellular Component	GO:0042383	sarcolemma	Slc2a4	IDA		Rat	PMID:10336852\|RGD:12879857
Cellular Component	GO:0042383	sarcolemma	Slc2a4	IDA		Rat	PMID:12388133\|RGD:2306288
Cellular Component	GO:0042383	sarcolemma	Slc2a4	IDA		Rat	PMID:1881917\|RGD:2306204
Cellular Component	GO:0042383	sarcolemma	Slc2a4	IDA		Rat	PMID:20868366\|RGD:7349316
Cellular Component	GO:0042383	sarcolemma	Slc2a4	IDA		Rat	PMID:11325341\|RGD:25671394
Cellular Component	GO:0016529	sarcoplasmic reticulum	Slc2a4	IDA		Rat	PMID:29676955\|RGD:13703029
Cellular Component	GO:0030315	T-tubule	Slc2a4	IDA		Rat	PMID:20868366\|RGD:7349316
Cellular Component	GO:0005802	trans-Golgi network	SLC2A4	IDA		Human	PMID:12467732
Cellular Component	GO:0030140	trans-Golgi network transport vesicle	Slc2a4	IDA		Mouse	PMID:17003038
Cellular Component	GO:0031982	vesicle	Slc2a4	IDA		Rat	PMID:11489215\|RGD:1582104
Cellular Component	GO:0012506	vesicle membrane	SLC2A4	IDA		Human	PMID:14562105
Biological Process	GO:0010021	amylopectin biosynthetic process	Slc2a4	IDA		Mouse	PMID:14562105
Biological Process	GO:0050873	brown fat cell differentiation	Slc2a4	IDA		Mouse	PMID:18492766
Biological Process	GO:0071456	cellular response to hypoxia	Slc2a4	IDA		Rat	PMID:20868366\|RGD:7349316
Biological Process	GO:0032869	cellular response to insulin stimulus	SLC2A4	IDA		Human	PMID:12556481
Biological Process	GO:0032869	cellular response to insulin stimulus	Slc2a4	IDA		Mouse	MGI:MGI:6162416\|PMID:26240143
Biological Process	GO:0032869	cellular response to insulin stimulus	Slc2a4	IDA		Mouse	MGI:MGI:5292403\|PMID:21907143
Biological Process	GO:0032869	cellular response to insulin stimulus	Slc2a4	IDA		Mouse	PMID:18227281
Biological Process	GO:0032869	cellular response to insulin stimulus	Slc2a4	IEP		Rat	PMID:20868366\|RGD:7349316
Biological Process	GO:0071470	cellular response to osmotic stress	Slc2a4	IDA		Mouse	PMID:18227281
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Slc2a4	IDA		Mouse	PMID:1618860
Biological Process	GO:0042593	glucose homeostasis	SLC2A4	IDA		Human	PMID:14562105
Biological Process	GO:0042593	glucose homeostasis	SLC2A4	IDA		Human	PMID:17003346
Biological Process	GO:0046323	glucose import	Slc2a4	IMP		Rat	PMID:20080987\|RGD:12903235
Biological Process	GO:0044381	glucose import in response to insulin stimulus	Slc2a4	IDA		Mouse	MGI:MGI:6162416\|PMID:26240143
Biological Process	GO:0044381	glucose import in response to insulin stimulus	Slc2a4	IDA		Mouse	PMID:26629404
Biological Process	GO:0044381	glucose import in response to insulin stimulus	Slc2a4	IDA		Rat	PMID:2211693\|RGD:2303167
Biological Process	GO:0044381	glucose import in response to insulin stimulus	Slc2a4	IDA		Rat	PMID:2645527\|RGD:14402447
Biological Process	GO:0044381	glucose import in response to insulin stimulus	Slc2a4	IDA		Rat	PMID:2649253\|RGD:729967
Biological Process	GO:1904659	glucose transmembrane transport	Slc2a4	IDA		Mouse	PMID:12097321
Biological Process	GO:1904659	glucose transmembrane transport	Slc2a4	IDA		Mouse	PMID:15857891
Biological Process	GO:1904659	glucose transmembrane transport	Slc2a4	IDA		Rat	PMID:1733237\|RGD:2306212
Biological Process	GO:1904659	glucose transmembrane transport	Slc2a4	IDA		Rat	PMID:2211693\|RGD:2303167
Biological Process	GO:1904659	glucose transmembrane transport	Slc2a4	IDA		Rat	PMID:2645527\|RGD:14402447
Biological Process	GO:1904659	glucose transmembrane transport	Slc2a4	IDA		Rat	PMID:2649253\|RGD:729967
Biological Process	GO:1904659	glucose transmembrane transport	Slc2a4	IMP		Rat	PMID:9059504\|RGD:730188
Biological Process	GO:0007611	learning or memory	Slc2a4	IDA		Rat	PMID:27881773\|RGD:25671385
Biological Process	GO:0007616	long-term memory	Slc2a4	IMP		Rat	PMID:27881773\|RGD:25671385
Biological Process	GO:0031550	positive regulation of brain-derived neurotrophic factor receptor signaling pathway	Slc2a4	IMP		Rat	PMID:27881773\|RGD:25671385
Biological Process	GO:0098694	regulation of synaptic vesicle budding from presynaptic endocytic zone membrane	Slc2a4	IDA		Rat	PMID:28111082\|RGD:13702195
Biological Process	GO:0098694	regulation of synaptic vesicle budding from presynaptic endocytic zone membrane	Slc2a4	IMP		Rat	PMID:28111082\|RGD:13702195
Biological Process	GO:0045471	response to ethanol	Slc2a4	IEP		Rat	PMID:18959809\|RGD:2313623
Biological Process	GO:0007614	short-term memory	Slc2a4	IMP		Rat	PMID:27881773\|RGD:25671385

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.