Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Slc30a8

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SLC30A8
- Mouse genes Slc30a8
- Rat genes Slc30a8
- Zfish genes slc30a8
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc30a8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:P08563:PRO_0000041304	Human	PMID:24955142
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q96BA8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q96BA8	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:A8MZ59	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:O15173	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:O15529	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:O60636	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:O60883	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:O95197-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:O95562	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:O95807	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:P12004	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:P13236	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:P15941-11	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:P16157-17	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:P17152	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:P23763-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:P26678	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:P30519	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:P43378	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:P54219-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:P56747	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:P60508	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:P63027	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q13323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q14416	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q15125	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q16617	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q4KMG9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q5T4F4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q7Z7G2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q8IV31	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q8N2H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q8N9I0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q8NBQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q8NC24	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q8TBE3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q8TCZ2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q8WV19	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q8WWF3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q8WY91	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q8WZ55	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q96EC8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q96FZ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q96GQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q96HE8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q96HR9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q96IV6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q96KR6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q96MG2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q96Q45-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q96TC7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q99640-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q99675	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q99726	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q9BSR8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q9BTX3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q9BUN8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q9BXK5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q9C0I4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q9GZR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q9H6H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q9HD20-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q9NP66	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q9NP94	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q9NPE6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q9NR31	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q9NUU6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q9NVJ2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q9NY72	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q9P0S3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q9P0T7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q9Y282	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC30A8	IPI	UniProtKB:Q9Y6D0	Human	PMID:32296183
Molecular Function	GO:0042803	protein homodimerization activity	Slc30a8	IPI	UniProtKB:Q8BGG0	Mouse	MGI:MGI:4442963\|PMID:19095428
Molecular Function	GO:0005385	zinc ion transmembrane transporter activity	SLC30A8	IDA		Human	PMID:15331542
Molecular Function	GO:0005385	zinc ion transmembrane transporter activity	Slc30a8	IMP	MGI:MGI:4362061	Mouse	PMID:19542200
Molecular Function	GO:0005385	zinc ion transmembrane transporter activity	Slc30a8	IMP	MGI:MGI:4362060	Mouse	PMID:20424817
Molecular Function	GO:0005385	zinc ion transmembrane transporter activity	Slc30a8	IMP	MGI:MGI:4362061	Mouse	PMID:19706465
Molecular Function	GO:0140826	zinc:proton antiporter activity	SLC30A8	IDA		Human	PMID:32723473
Cellular Component	GO:0031410	cytoplasmic vesicle	Slc30a8	IDA		Mouse	MGI:MGI:4442963\|PMID:19095428
Cellular Component	GO:0031410	cytoplasmic vesicle	Slc30a8	IDA		Rat	PMID:19095428\|RGD:2315024
Cellular Component	GO:0005886	plasma membrane	SLC30A8	IDA		Human	PMID:15331542
Cellular Component	GO:0030141	secretory granule	SLC30A8	IDA		Human	PMID:15331542
Cellular Component	GO:0030141	secretory granule	Slc30a8	IDA		Mouse	PMID:20424817
Cellular Component	GO:0030667	secretory granule membrane	SLC30A8	IDA		Human	PMID:16984975
Cellular Component	GO:0030667	secretory granule membrane	Slc30a8	IDA		Mouse	PMID:20424817
Biological Process	GO:0031018	endocrine pancreas development	slc30a8	IMP	ZFIN:ZDB-MRPHLNO-160621-56	Zfish	PMID:26963759
Biological Process	GO:0042593	glucose homeostasis	slc30a8	IMP	ZFIN:ZDB-MRPHLNO-160621-56	Zfish	PMID:26963759
Biological Process	GO:0030070	insulin processing	Slc30a8	IMP	MGI:MGI:4362061	Mouse	PMID:19542200
Biological Process	GO:0030070	insulin processing	Slc30a8	IMP	MGI:MGI:4362061	Mouse	PMID:19706465
Biological Process	GO:0030073	insulin secretion	SLC30A8	IMP		Human	PMID:16984975
Biological Process	GO:0030073	insulin secretion	Slc30a8	IMP		Mouse	MGI:MGI:4359332\|PMID:19450229
Biological Process	GO:0030073	insulin secretion	Slc30a8	IMP		Rat	PMID:19479076\|RGD:2315022
Biological Process	GO:0006882	intracellular zinc ion homeostasis	Slc30a8	IMP		Mouse	MGI:MGI:4359332\|PMID:19450229
Biological Process	GO:0006882	intracellular zinc ion homeostasis	Slc30a8	IMP		Rat	PMID:19479076\|RGD:2315022
Biological Process	GO:0032024	positive regulation of insulin secretion	Slc30a8	IMP		Rat	PMID:19479076\|RGD:2315022
Biological Process	GO:0061088	regulation of sequestering of zinc ion	Slc30a8	IMP		Rat	PMID:19479076\|RGD:2315022
Biological Process	GO:0060627	regulation of vesicle-mediated transport	Slc30a8	IMP		Rat	PMID:19479076\|RGD:2315022
Biological Process	GO:0009749	response to glucose	SLC30A8	IMP		Human	PMID:16984975
Biological Process	GO:0009749	response to glucose	Slc30a8	IMP		Mouse	MGI:MGI:4359332\|PMID:19450229
Biological Process	GO:0009749	response to glucose	Slc30a8	IMP		Rat	PMID:19479076\|RGD:2315022
Biological Process	GO:0070555	response to interleukin-1	Slc30a8	IEP		Rat	PMID:19243577\|RGD:2315023
Biological Process	GO:0034341	response to type II interferon	Slc30a8	IEP		Rat	PMID:19243577\|RGD:2315023
Biological Process	GO:0032119	sequestering of zinc ion	SLC30A8	IDA		Human	PMID:15331542
Biological Process	GO:0003323	type B pancreatic cell development	slc30a8	IMP	ZFIN:ZDB-MRPHLNO-160621-56	Zfish	PMID:26963759
Biological Process	GO:0062111	zinc ion import into organelle	SLC30A8	IMP		Human	PMID:16984975
Biological Process	GO:0006829	zinc ion transport	SLC30A8	IDA		Human	PMID:15331542

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.