Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC38A1
  • Mouse genes Slc38a1
  • Rat genes Slc38a1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc38a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015655	alanine:sodium symporter activity	Slc38a1	IDA		Rat	PMID:11692272|RGD:152995572
Molecular Function	GO:0005283	amino acid:sodium symporter activity	Slc38a1	IDA		Rat	PMID:11692272|RGD:152995572
Molecular Function	GO:0015375	glycine:sodium symporter activity	Slc38a1	IDA		Rat	PMID:11692272|RGD:152995572
Molecular Function	GO:0015179	L-amino acid transmembrane transporter activity	Slc38a1	IDA		Rat	PMID:12684517|RGD:1299220
Molecular Function	GO:0015186	L-glutamine transmembrane transporter activity	Slc38a1	IDA		Mouse	MGI:MGI:7310371|PMID:27655909
Molecular Function	GO:0015186	L-glutamine transmembrane transporter activity	Slc38a1	IDA		Mouse	PMID:11325958
Molecular Function	GO:0005295	neutral L-amino acid:sodium symporter activity	Slc38a1	IDA		Rat	PMID:10660562|RGD:68922
Molecular Function	GO:0005295	neutral L-amino acid:sodium symporter activity	Slc38a1	IDA		Rat	PMID:11756489|RGD:70402
Molecular Function	GO:0005295	neutral L-amino acid:sodium symporter activity	Slc38a1	IDA		Rat	PMID:12684517|RGD:1299220
Molecular Function	GO:0005298	proline:sodium symporter activity	Slc38a1	IDA		Rat	PMID:11692272|RGD:152995572
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:Q969F0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:A5PKU2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:O15173	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:O15529	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:O15552	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:O95393	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:O95968	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:P0DN84	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:P11912	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:P24593	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:Q01453	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:Q01638-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:Q14416	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:Q14973	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:Q6ZT21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:Q86WK6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:Q86Z23	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:Q8N6R1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:Q8WWF3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:Q969F0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:Q9BQ51	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:Q9BZL3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:Q9H2L4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:Q9NS64	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:Q9NY72	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A1	IPI	UniProtKB:Q9UKG4	Human	PMID:32296183
Cellular Component	GO:0030424	axon	Slc38a1	IDA		Mouse	PMID:11325958
Cellular Component	GO:0016323	basolateral plasma membrane	Slc38a1	IDA		Mouse	MGI:MGI:6436375|PMID:32046769
Cellular Component	GO:0098591	external side of apical plasma membrane	Slc38a1	IDA		Rat	PMID:12684517|RGD:1299220
Cellular Component	GO:0070062	extracellular exosome	SLC38A1	HDA		Human	PMID:20458337
Cellular Component	GO:0016020	membrane	Slc38a1	IDA		Mouse	PMID:11325958
Cellular Component	GO:0043025	neuronal cell body	Slc38a1	IDA		Rat	PMID:12684517|RGD:1299220
Cellular Component	GO:0005886	plasma membrane	SLC38A1	IDA		Human	PMID:23137377
Cellular Component	GO:0005886	plasma membrane	Slc38a1	IDA		Mouse	PMID:11325958
Cellular Component	GO:0005886	plasma membrane	Slc38a1	IDA		Rat	PMID:10660562|RGD:68922
Cellular Component	GO:0005886	plasma membrane	Slc38a1	IDA		Rat	PMID:19751803|RGD:9999214
Biological Process	GO:0043090	amino acid import	Slc38a1	IDA		Rat	PMID:11692272|RGD:152995572
Biological Process	GO:0043090	amino acid import	Slc38a1	IDA		Rat	PMID:11756489|RGD:70402
Biological Process	GO:0007565	female pregnancy	Slc38a1	IEP		Rat	PMID:19892400|RGD:9999228
Biological Process	GO:0009449	gamma-aminobutyric acid biosynthetic process	Slc38a1	IMP		Mouse	MGI:MGI:6795362|PMID:32668809
Biological Process	GO:0006541	glutamine metabolic process	Slc38a1	IDA		Rat	PMID:10660562|RGD:68922
Biological Process	GO:0006868	glutamine transport	Slc38a1	IDA		Mouse	MGI:MGI:7310371|PMID:27655909
Biological Process	GO:0006868	glutamine transport	Slc38a1	IMP		Mouse	MGI:MGI:6795362|PMID:32668809
Biological Process	GO:0006868	glutamine transport	Slc38a1	IDA		Mouse	PMID:11325958
Biological Process	GO:1902475	L-alpha-amino acid transmembrane transport	Slc38a1	IDA		Rat	PMID:12684517|RGD:1299220
Biological Process	GO:0015804	neutral amino acid transport	Slc38a1	IDA		Rat	PMID:12684517|RGD:1299220
Biological Process	GO:1901036	positive regulation of L-glutamine import across plasma membrane	Slc38a1	IDA		Rat	PMID:10660562|RGD:68922
Biological Process	GO:0048167	regulation of synaptic plasticity	Slc38a1	IMP		Mouse	MGI:MGI:6382567|PMID:31050701
Biological Process	GO:0032228	regulation of synaptic transmission, GABAergic	Slc38a1	IMP		Mouse	MGI:MGI:6382567|PMID:31050701

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern