Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Slc38a2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SLC38A2
- Mouse genes Slc38a2
- Rat genes Slc38a2
- Zfish genes slc38a2
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc38a2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015172	acidic amino acid transmembrane transporter activity	Slc38a2	IDA		Rat	PMID:10811809\|RGD:68921
Molecular Function	GO:0015655	alanine:sodium symporter activity	Slc38a2	IDA		Rat	PMID:10811809\|RGD:68921
Molecular Function	GO:0015655	alanine:sodium symporter activity	Slc38a2	IDA		Rat	PMID:18319257\|RGD:152995546
Molecular Function	GO:0015655	alanine:sodium symporter activity	Slc38a2	IDA		Rat	PMID:19589777\|RGD:152995570
Molecular Function	GO:0015171	amino acid transmembrane transporter activity	SLC38A2	IMP		Human	PMID:15922329
Molecular Function	GO:0015171	amino acid transmembrane transporter activity	SLC38A2	IDA		Human	PMID:16621798
Molecular Function	GO:0015171	amino acid transmembrane transporter activity	Slc38a2	IDA		Mouse	PMID:17003038
Molecular Function	GO:0005283	amino acid:sodium symporter activity	SLC38A2	IDA		Human	PMID:15774260
Molecular Function	GO:0005283	amino acid:sodium symporter activity	Slc38a2	IDA		Rat	PMID:12054432\|RGD:152995574
Molecular Function	GO:0015186	L-glutamine transmembrane transporter activity	Slc38a2	IDA		Mouse	MGI:MGI:6107400\|PMID:27742667
Molecular Function	GO:0015186	L-glutamine transmembrane transporter activity	Slc38a2	IDA		Rat	PMID:15218073\|RGD:15090853
Molecular Function	GO:0015186	L-glutamine transmembrane transporter activity	Slc38a2	IDA		Rat	PMID:18832333\|RGD:152995567
Molecular Function	GO:0015194	L-serine transmembrane transporter activity	Slc38a2	IDA		Rat	PMID:15218073\|RGD:15090853
Molecular Function	GO:0015175	neutral L-amino acid transmembrane transporter activity	Slc38a2	IMP		Mouse	MGI:MGI:7294461\|PMID:34406367
Molecular Function	GO:0005295	neutral L-amino acid:sodium symporter activity	SLC38A2	IDA		Human	PMID:10930503
Molecular Function	GO:0005295	neutral L-amino acid:sodium symporter activity	Slc38a2	IDA		Rat	PMID:10747860\|RGD:68920
Molecular Function	GO:0005295	neutral L-amino acid:sodium symporter activity	Slc38a2	IDA		Rat	PMID:10859363\|RGD:1299212
Molecular Function	GO:0005295	neutral L-amino acid:sodium symporter activity	Slc38a2	IDA		Rat	PMID:11756489\|RGD:70402
Molecular Function	GO:0005295	neutral L-amino acid:sodium symporter activity	Slc38a2	IDA		Rat	PMID:16629640\|RGD:152995548
Molecular Function	GO:0005295	neutral L-amino acid:sodium symporter activity	Slc38a2	IDA		Rat	PMID:27355203\|RGD:152995578
Molecular Function	GO:0005298	proline:sodium symporter activity	Slc38a2	IDA		Rat	PMID:11716780\|RGD:152995560
Molecular Function	GO:0005515	protein binding	SLC38A2	IPI	UniProtKB:Q99942	Human	PMID:25759021
Molecular Function	GO:0005515	protein binding	SLC38A2	IPI	UniProtKB:Q96Q45-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC38A2	IPI	UniProtKB:Q9UHG0	Human	PMID:32296183
Cellular Component	GO:0030424	axon	Slc38a2	IDA		Rat	PMID:15561425\|RGD:9999220
Cellular Component	GO:0005903	brush border	Slc38a2	IDA		Rat	PMID:20338592\|RGD:9999218
Cellular Component	GO:0005737	cytoplasm	SLC38A2	IDA		Human	PMID:15581851
Cellular Component	GO:0030425	dendrite	Slc38a2	IDA		Rat	PMID:21718781\|RGD:9999217
Cellular Component	GO:0043025	neuronal cell body	Slc38a2	IDA		Rat	PMID:15561425\|RGD:9999220
Cellular Component	GO:0005886	plasma membrane	SLC38A2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	SLC38A2	IDA		Human	PMID:15581851
Cellular Component	GO:0005886	plasma membrane	Slc38a2	IDA		Mouse	MGI:MGI:3697046\|PMID:17050538
Cellular Component	GO:0005886	plasma membrane	Slc38a2	IDA		Mouse	PMID:17003038
Cellular Component	GO:0005886	plasma membrane	Slc38a2	IDA		Rat	PMID:11311116\|RGD:68721
Cellular Component	GO:0005886	plasma membrane	Slc38a2	IDA		Rat	PMID:11834730\|RGD:1299211
Cellular Component	GO:0005886	plasma membrane	Slc38a2	IDA		Rat	PMID:12054432\|RGD:152995574
Cellular Component	GO:0005886	plasma membrane	Slc38a2	IDA		Rat	PMID:15561425\|RGD:9999220
Cellular Component	GO:0005886	plasma membrane	Slc38a2	IDA		Rat	PMID:19589777\|RGD:152995570
Cellular Component	GO:0005886	plasma membrane	Slc38a2	IDA		Rat	PMID:19751803\|RGD:9999214
Cellular Component	GO:0005886	plasma membrane	Slc38a2	IDA		Rat	PMID:27355203\|RGD:152995578
Cellular Component	GO:0005886	plasma membrane	Slc38a2	IDA		Rat	PMID:29678469\|RGD:152995541
Cellular Component	GO:0042383	sarcolemma	Slc38a2	IDA		Rat	PMID:11834730\|RGD:1299211
Biological Process	GO:0032328	alanine transport	Slc38a2	IDA		Rat	PMID:10811809\|RGD:68921
Biological Process	GO:0032328	alanine transport	Slc38a2	IDA		Rat	PMID:18319257\|RGD:152995546
Biological Process	GO:0032328	alanine transport	Slc38a2	IDA		Rat	PMID:19589777\|RGD:152995570
Biological Process	GO:0043090	amino acid import	Slc38a2	IDA		Rat	PMID:11756489\|RGD:70402
Biological Process	GO:0003333	amino acid transmembrane transport	SLC38A2	IMP	CHEBI:15428\|CHEBI:16449\|CHEBI:16811\|CHEBI:17822\|CHEBI:22653\|CHEBI:25017\|CHEBI:26271\|CHEBI:26986\|CHEBI:28300	Human	PMID:10930503
Biological Process	GO:0003333	amino acid transmembrane transport	Slc38a2	IDA		Mouse	MGI:MGI:3697008\|PMID:17003038
Biological Process	GO:0006865	amino acid transport	SLC38A2	IDA		Human	PMID:15774260
Biological Process	GO:0006865	amino acid transport	SLC38A2	IMP		Human	PMID:15922329
Biological Process	GO:0006865	amino acid transport	SLC38A2	IDA		Human	PMID:16621798
Biological Process	GO:0006865	amino acid transport	Slc38a2	IDA		Mouse	PMID:17003038
Biological Process	GO:0034198	cellular response to amino acid starvation	Slc38a2	IEP		Rat	PMID:11311116\|RGD:68721
Biological Process	GO:1903841	cellular response to arsenite(3-)	SLC38A2	IMP		Human	PMID:22215663
Biological Process	GO:0071260	cellular response to mechanical stimulus	Slc38a2	IEP		Rat	PMID:15288886\|RGD:9999216
Biological Process	GO:0021987	cerebral cortex development	Slc38a2	IEP		Rat	PMID:21718781\|RGD:9999217
Biological Process	GO:0007565	female pregnancy	Slc38a2	IEP		Rat	PMID:19892400\|RGD:9999228
Biological Process	GO:0006868	glutamine transport	Slc38a2	IDA		Mouse	MGI:MGI:6107400\|PMID:27742667
Biological Process	GO:0006868	glutamine transport	Slc38a2	IDA		Rat	PMID:15218073\|RGD:15090853
Biological Process	GO:0031460	glycine betaine transport	Slc38a2	IDA		Rat	PMID:24434061\|RGD:9999215
Biological Process	GO:1903803	L-glutamine import across plasma membrane	Slc38a2	IDA		Rat	PMID:18832333\|RGD:152995567
Biological Process	GO:1904271	L-proline import across plasma membrane	Slc38a2	IDA		Rat	PMID:11716780\|RGD:152995560
Biological Process	GO:1903812	L-serine import across plasma membrane	Slc38a2	IDA		Rat	PMID:16629640\|RGD:152995548
Biological Process	GO:0015825	L-serine transport	Slc38a2	IDA		Rat	PMID:15218073\|RGD:15090853
Biological Process	GO:0015804	neutral amino acid transport	SLC38A2	IDA		Human	PMID:10930503
Biological Process	GO:0015804	neutral amino acid transport	Slc38a2	IDA		Rat	PMID:10747860\|RGD:68920
Biological Process	GO:0015804	neutral amino acid transport	Slc38a2	IDA		Rat	PMID:10859363\|RGD:1299212
Biological Process	GO:0015804	neutral amino acid transport	Slc38a2	IDA		Rat	PMID:12054432\|RGD:152995574
Biological Process	GO:0015804	neutral amino acid transport	Slc38a2	IDA		Rat	PMID:16629640\|RGD:152995548
Biological Process	GO:0015804	neutral amino acid transport	Slc38a2	IDA		Rat	PMID:27355203\|RGD:152995578
Biological Process	GO:0010628	positive regulation of gene expression	SLC38A2	IPI	UniProtKB:P35638	Human	PMID:22215663
Biological Process	GO:0033120	positive regulation of RNA splicing	SLC38A2	IPI	UniProtKB:P17861	Human	PMID:22215663
Biological Process	GO:0015824	proline transport	Slc38a2	IMP		Mouse	MGI:MGI:7294461\|PMID:34406367
Biological Process	GO:0080135	regulation of cellular response to stress	SLC38A2	IMP		Human	PMID:22215663
Biological Process	GO:1903294	regulation of glutamate secretion, neurotransmission	Slc38a2	IDA		Rat	PMID:18832333\|RGD:152995567
Biological Process	GO:0014850	response to muscle activity	Slc38a2	IEP		Rat	PMID:24016666\|RGD:151361119

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.