Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC38A3
  • Mouse genes Slc38a3
  • Rat genes Slc38a3
  • Zfish genes slc38a3a,slc38a3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc38a3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015180	L-alanine transmembrane transporter activity	SLC38A3	IDA		Human	PMID:10823827
Molecular Function	GO:0015182	L-asparagine transmembrane transporter activity	SLC38A3	IDA		Human	PMID:10823827
Molecular Function	GO:0015182	L-asparagine transmembrane transporter activity	Slc38a3	IDA		Rat	PMID:10619430|RGD:634178
Molecular Function	GO:0015182	L-asparagine transmembrane transporter activity	Slc38a3	IDA		Rat	PMID:10823827|RGD:8554577
Molecular Function	GO:0140831	L-asparagine, sodium:proton antiporter activity	Slc38a3	IDA		Mouse	MGI:MGI:7310198|PMID:16249471
Molecular Function	GO:0140831	L-asparagine, sodium:proton antiporter activity	Slc38a3	IDA		Rat	PMID:11742981|RGD:152995542
Molecular Function	GO:0140831	L-asparagine, sodium:proton antiporter activity	Slc38a3	IDA		Rat	PMID:19596860|RGD:152995538
Molecular Function	GO:0140831	L-asparagine, sodium:proton antiporter activity	Slc38a3	IDA		Rat	PMID:21525297|RGD:152995537
Molecular Function	GO:0140831	L-asparagine, sodium:proton antiporter activity	Slc38a3	IDA		Rat	PMID:28272791|RGD:152995559
Molecular Function	GO:0015186	L-glutamine transmembrane transporter activity	SLC38A3	IDA		Human	PMID:10823827
Molecular Function	GO:0015186	L-glutamine transmembrane transporter activity	Slc38a3	IDA		Mouse	PMID:10716701
Molecular Function	GO:0015186	L-glutamine transmembrane transporter activity	Slc38a3	IDA		Rat	PMID:10619430|RGD:634178
Molecular Function	GO:0015186	L-glutamine transmembrane transporter activity	Slc38a3	IDA		Rat	PMID:10823827|RGD:8554577
Molecular Function	GO:0140830	L-glutamine, sodium:proton antiporter activity	Slc38a3	IDA		Mouse	MGI:MGI:7310198|PMID:16249471
Molecular Function	GO:0140830	L-glutamine, sodium:proton antiporter activity	Slc38a3	IDA		Mouse	MGI:MGI:7310199|PMID:18689705
Molecular Function	GO:0140830	L-glutamine, sodium:proton antiporter activity	Slc38a3	IDA		Rat	PMID:11742981|RGD:152995542
Molecular Function	GO:0140830	L-glutamine, sodium:proton antiporter activity	Slc38a3	IDA		Rat	PMID:11850497|RGD:152995544
Molecular Function	GO:0140830	L-glutamine, sodium:proton antiporter activity	Slc38a3	IDA		Rat	PMID:17148440|RGD:9999222
Molecular Function	GO:0140830	L-glutamine, sodium:proton antiporter activity	Slc38a3	IDA		Rat	PMID:19596860|RGD:152995538
Molecular Function	GO:0140830	L-glutamine, sodium:proton antiporter activity	Slc38a3	IDA		Rat	PMID:21525297|RGD:152995537
Molecular Function	GO:0140830	L-glutamine, sodium:proton antiporter activity	Slc38a3	IDA		Rat	PMID:28272791|RGD:152995559
Molecular Function	GO:0140830	L-glutamine, sodium:proton antiporter activity	Slc38a3	IDA		Rat	PMID:29561757|RGD:152995547
Molecular Function	GO:0005290	L-histidine transmembrane transporter activity	SLC38A3	IDA		Human	PMID:10823827
Molecular Function	GO:0005290	L-histidine transmembrane transporter activity	Slc38a3	IDA		Mouse	PMID:10716701
Molecular Function	GO:0005290	L-histidine transmembrane transporter activity	Slc38a3	IDA		Rat	PMID:10619430|RGD:634178
Molecular Function	GO:0140832	L-histidine, sodium:proton antiporter activity	Slc38a3	IDA		Mouse	MGI:MGI:7310200|PMID:15899884
Molecular Function	GO:0140832	L-histidine, sodium:proton antiporter activity	Slc38a3	IDA		Rat	PMID:11742981|RGD:152995542
Molecular Function	GO:0140832	L-histidine, sodium:proton antiporter activity	Slc38a3	IDA		Rat	PMID:28272791|RGD:152995559
Molecular Function	GO:0005295	neutral L-amino acid:sodium symporter activity	Slc38a3	IDA		Rat	PMID:16249471|RGD:152995568
Cellular Component	GO:0016324	apical plasma membrane	Slc38a3	IDA		Mouse	MGI:MGI:6436375|PMID:32046769
Cellular Component	GO:0016323	basolateral plasma membrane	Slc38a3	IDA		Rat	PMID:15716335|RGD:9999226
Cellular Component	GO:0016020	membrane	Slc38a3	IDA		Mouse	PMID:19458124
Cellular Component	GO:0005886	plasma membrane	SLC38A3	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005886	plasma membrane	Slc38a3	IDA		Mouse	PMID:10716701
Cellular Component	GO:0005886	plasma membrane	Slc38a3	IDA		Rat	PMID:10619430|RGD:634178
Cellular Component	GO:0005886	plasma membrane	Slc38a3	IDA		Rat	PMID:17148440|RGD:9999222
Cellular Component	GO:0005886	plasma membrane	Slc38a3	IDA		Rat	PMID:19596860|RGD:152995538
Cellular Component	GO:0005886	plasma membrane	Slc38a3	IDA		Rat	PMID:21525297|RGD:152995537
Cellular Component	GO:0005886	plasma membrane	Slc38a3	IDA		Rat	PMID:29561757|RGD:152995547
Biological Process	GO:0006867	asparagine transport	SLC38A3	IDA		Human	PMID:10823827
Biological Process	GO:0006867	asparagine transport	Slc38a3	IDA		Rat	PMID:10619430|RGD:634178
Biological Process	GO:0006867	asparagine transport	Slc38a3	IDA		Rat	PMID:10823827|RGD:8554577
Biological Process	GO:0006867	asparagine transport	Slc38a3	IDA		Rat	PMID:19596860|RGD:152995538
Biological Process	GO:0007420	brain development	Slc38a3	IEP		Rat	PMID:12528181|RGD:632946
Biological Process	GO:0051365	cellular response to potassium ion starvation	Slc38a3	IDA		Mouse	PMID:19458124
Biological Process	GO:0007565	female pregnancy	Slc38a3	IEP		Rat	PMID:19892400|RGD:9999228
Biological Process	GO:0010585	glutamine secretion	Slc38a3	IDA		Mouse	MGI:MGI:6878700|PMID:29561757
Biological Process	GO:0010585	glutamine secretion	Slc38a3	IDA		Rat	PMID:11850497|RGD:152995544
Biological Process	GO:0010585	glutamine secretion	Slc38a3	IDA		Rat	PMID:17909850|RGD:152995561
Biological Process	GO:0010585	glutamine secretion	Slc38a3	IDA		Rat	PMID:28272791|RGD:152995559
Biological Process	GO:0010585	glutamine secretion	Slc38a3	IDA		Rat	PMID:29561757|RGD:152995547
Biological Process	GO:0006868	glutamine transport	SLC38A3	IDA		Human	PMID:10823827
Biological Process	GO:0006868	glutamine transport	Slc38a3	IDA		Mouse	PMID:10716701
Biological Process	GO:0006868	glutamine transport	Slc38a3	IDA		Rat	PMID:10619430|RGD:634178
Biological Process	GO:0006868	glutamine transport	Slc38a3	IDA		Rat	PMID:10823827|RGD:8554577
Biological Process	GO:0006868	glutamine transport	Slc38a3	IDA		Rat	PMID:16249471|RGD:152995568
Biological Process	GO:0006868	glutamine transport	Slc38a3	IDA		Rat	PMID:19596860|RGD:152995538
Biological Process	GO:0015817	histidine transport	SLC38A3	IDA		Human	PMID:10823827
Biological Process	GO:0015817	histidine transport	Slc38a3	IDA		Mouse	PMID:10716701
Biological Process	GO:0015817	histidine transport	Slc38a3	IDA		Rat	PMID:10619430|RGD:634178
Biological Process	GO:0080144	intracellular amino acid homeostasis	Slc38a3	IMP		Mouse	MGI:MGI:5790969|PMID:26490457
Biological Process	GO:0015808	L-alanine transport	SLC38A3	IDA		Human	PMID:10823827
Biological Process	GO:1903811	L-asparagine import across plasma membrane	Slc38a3	IDA		Rat	PMID:11742981|RGD:152995542
Biological Process	GO:1903811	L-asparagine import across plasma membrane	Slc38a3	IDA		Rat	PMID:21525297|RGD:152995537
Biological Process	GO:1903811	L-asparagine import across plasma membrane	Slc38a3	IDA		Rat	PMID:28272791|RGD:152995559
Biological Process	GO:1903803	L-glutamine import across plasma membrane	Slc38a3	IDA		Mouse	MGI:MGI:7310199|PMID:18689705
Biological Process	GO:1903803	L-glutamine import across plasma membrane	Slc38a3	IDA		Rat	PMID:11742981|RGD:152995542
Biological Process	GO:1903803	L-glutamine import across plasma membrane	Slc38a3	IDA		Rat	PMID:11850497|RGD:152995544
Biological Process	GO:1903803	L-glutamine import across plasma membrane	Slc38a3	IDA		Rat	PMID:17909850|RGD:152995561
Biological Process	GO:1903803	L-glutamine import across plasma membrane	Slc38a3	IDA		Rat	PMID:21525297|RGD:152995537
Biological Process	GO:1903803	L-glutamine import across plasma membrane	Slc38a3	IDA		Rat	PMID:28272791|RGD:152995559
Biological Process	GO:1903810	L-histidine import across plasma membrane	Slc38a3	IDA		Mouse	MGI:MGI:7310200|PMID:15899884
Biological Process	GO:1902024	L-histidine transport	Slc38a3	IDA		Rat	PMID:11742981|RGD:152995542
Biological Process	GO:1902024	L-histidine transport	Slc38a3	IDA		Rat	PMID:28272791|RGD:152995559
Biological Process	GO:2000487	positive regulation of glutamine transport	Slc38a3	IDA		Rat	PMID:17148440|RGD:9999222
Biological Process	GO:0061402	positive regulation of transcription from RNA polymerase II promoter in response to acidic pH	Slc38a3	IDA		Mouse	PMID:19458124

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern