Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Slc39a14

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SLC39A14
- Mouse genes Slc39a14
- Rat genes Slc39a14
- Zfish genes slc39a14
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc39a14

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015086	cadmium ion transmembrane transporter activity	Slc39a14	IDA		Mouse	MGI:MGI:6383280\|PMID:18270315
Molecular Function	GO:0015086	cadmium ion transmembrane transporter activity	Slc39a14	IDA		Mouse	MGI:MGI:5295560\|PMID:21653899
Molecular Function	GO:0015093	ferrous iron transmembrane transporter activity	Slc39a14	IDA		Mouse	PMID:16950869
Molecular Function	GO:0005381	iron ion transmembrane transporter activity	Slc39a14	IDA		Mouse	MGI:MGI:5295560\|PMID:21653899
Molecular Function	GO:0005384	manganese ion transmembrane transporter activity	SLC39A14	IMP		Human	PMID:31028174
Molecular Function	GO:0005384	manganese ion transmembrane transporter activity	Slc39a14	IDA		Mouse	MGI:MGI:6383280\|PMID:18270315
Molecular Function	GO:0005384	manganese ion transmembrane transporter activity	Slc39a14	IDA		Mouse	MGI:MGI:5295560\|PMID:21653899
Molecular Function	GO:0015296	monoatomic anion:monoatomic cation symporter activity	Slc39a14	IDA		Mouse	MGI:MGI:6383280\|PMID:18270315
Molecular Function	GO:0140410	monoatomic cation:bicarbonate symporter activity	SLC39A14	IDA		Human	PMID:31699897
Molecular Function	GO:0005385	zinc ion transmembrane transporter activity	SLC39A14	IDA		Human	PMID:15642354
Molecular Function	GO:0005385	zinc ion transmembrane transporter activity	SLC39A14	IDA		Human	PMID:21917916
Molecular Function	GO:0005385	zinc ion transmembrane transporter activity	Slc39a14	IDA		Mouse	MGI:MGI:5295560\|PMID:21653899
Molecular Function	GO:0005385	zinc ion transmembrane transporter activity	Slc39a14	IDA		Mouse	PMID:16950869
Cellular Component	GO:0016324	apical plasma membrane	SLC39A14	IDA		Human	PMID:31699897
Cellular Component	GO:0016323	basolateral plasma membrane	SLC39A14	IDA		Human	PMID:31028174
Cellular Component	GO:0016323	basolateral plasma membrane	SLC39A14	IDA		Human	PMID:31699897
Cellular Component	GO:0016323	basolateral plasma membrane	Slc39a14	IDA		Mouse	MGI:MGI:5907913\|PMID:28536273
Cellular Component	GO:0031901	early endosome membrane	SLC39A14	IDA		Human	PMID:20682781
Cellular Component	GO:0031901	early endosome membrane	SLC39A14	IDA		Human	PMID:27703010
Cellular Component	GO:0031902	late endosome membrane	SLC39A14	IDA		Human	PMID:27703010
Cellular Component	GO:0005765	lysosomal membrane	SLC39A14	IDA		Human	PMID:20682781
Cellular Component	GO:0016020	membrane	SLC39A14	IDA		Human	PMID:21917916
Cellular Component	GO:0005886	plasma membrane	SLC39A14	IDA		Human	PMID:15642354
Cellular Component	GO:0005886	plasma membrane	SLC39A14	IDA		Human	PMID:27231142
Cellular Component	GO:0005886	plasma membrane	SLC39A14	IDA		Human	PMID:27703010
Cellular Component	GO:0005886	plasma membrane	SLC39A14	IDA		Human	PMID:29621230
Cellular Component	GO:0005886	plasma membrane	Slc39a14	IDA		Mouse	MGI:MGI:4950776\|PMID:21445361
Cellular Component	GO:0005886	plasma membrane	Slc39a14	IDA		Mouse	PMID:16950869
Cellular Component	GO:0005886	plasma membrane	slc39a14	IDA		Zfish	PMID:27231142\|ZFIN:ZDB-PUB-160528-7
Biological Process	GO:0071333	cellular response to glucose stimulus	Slc39a14	IDA		Mouse	MGI:MGI:5812606\|PMID:27703010
Biological Process	GO:0032869	cellular response to insulin stimulus	Slc39a14	IMP		Mouse	MGI:MGI:5812606\|PMID:27703010
Biological Process	GO:0002062	chondrocyte differentiation	Slc39a14	IMP		Mouse	MGI:MGI:4950776\|PMID:21445361
Biological Process	GO:0006094	gluconeogenesis	Slc39a14	IMP		Mouse	MGI:MGI:4950776\|PMID:21445361
Biological Process	GO:0098739	import across plasma membrane	SLC39A14	IMP		Human	PMID:31028174
Biological Process	GO:0098662	inorganic cation transmembrane transport	Slc39a14	IDA		Mouse	MGI:MGI:6383280\|PMID:18270315
Biological Process	GO:0098662	inorganic cation transmembrane transport	Slc39a14	IDA		Mouse	MGI:MGI:5295560\|PMID:21653899
Biological Process	GO:0008286	insulin receptor signaling pathway	Slc39a14	IMP		Mouse	MGI:MGI:5812606\|PMID:27703010
Biological Process	GO:0006882	intracellular zinc ion homeostasis	SLC39A14	IDA		Human	PMID:15642354
Biological Process	GO:0006882	intracellular zinc ion homeostasis	SLC39A14	IDA		Human	PMID:21917916
Biological Process	GO:0006882	intracellular zinc ion homeostasis	Slc39a14	IMP		Mouse	MGI:MGI:5812606\|PMID:27703010
Biological Process	GO:0006882	intracellular zinc ion homeostasis	Slc39a14	IMP		Mouse	MGI:MGI:4950776\|PMID:21445361
Biological Process	GO:0033212	iron import into cell	SLC39A14	IMP		Human	PMID:20682781
Biological Process	GO:0033212	iron import into cell	Slc39a14	IMP		Mouse	MGI:MGI:6392986\|PMID:20682781
Biological Process	GO:0034755	iron ion transmembrane transport	SLC39A14	IMP		Human	PMID:20682781
Biological Process	GO:0034755	iron ion transmembrane transport	Slc39a14	IMP		Mouse	MGI:MGI:6392986\|PMID:20682781
Biological Process	GO:0034755	iron ion transmembrane transport	Slc39a14	IDA		Mouse	MGI:MGI:3687612\|PMID:16950869
Biological Process	GO:0034755	iron ion transmembrane transport	Slc39a14	IDA		Mouse	MGI:MGI:5295560\|PMID:21653899
Biological Process	GO:0006826	iron ion transport	Slc39a14	IDA		Mouse	PMID:16950869
Biological Process	GO:0055071	manganese ion homeostasis	Slc39a14	IMP		Mouse	MGI:MGI:6368748\|PMID:31028174
Biological Process	GO:0055071	manganese ion homeostasis	Slc39a14	IMP		Mouse	MGI:MGI:5907913\|PMID:28536273
Biological Process	GO:0055071	manganese ion homeostasis	slc39a14	IMP	ZFIN:ZDB-GENO-160805-3	Zfish	PMID:27231142
Biological Process	GO:0071421	manganese ion transmembrane transport	SLC39A14	IMP		Human	PMID:31028174
Biological Process	GO:0071421	manganese ion transmembrane transport	SLC39A14	IMP		Human	PMID:31699897
Biological Process	GO:0071421	manganese ion transmembrane transport	Slc39a14	IDA		Mouse	MGI:MGI:5295560\|PMID:21653899
Biological Process	GO:0071421	manganese ion transmembrane transport	Slc39a14	IDA		Mouse	MGI:MGI:6383280\|PMID:18270315
Biological Process	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	Slc39a14	IMP		Mouse	MGI:MGI:4950776\|PMID:21445361
Biological Process	GO:0045745	positive regulation of G protein-coupled receptor signaling pathway	Slc39a14	IMP		Mouse	MGI:MGI:4950776\|PMID:21445361
Biological Process	GO:0010817	regulation of hormone levels	Slc39a14	IMP		Mouse	MGI:MGI:4950776\|PMID:21445361
Biological Process	GO:0071578	zinc ion import across plasma membrane	SLC39A14	IDA		Human	PMID:15642354
Biological Process	GO:0071578	zinc ion import across plasma membrane	SLC39A14	IDA		Human	PMID:29621230
Biological Process	GO:0071577	zinc ion transmembrane transport	SLC39A14	IMP		Human	PMID:15642354
Biological Process	GO:0071577	zinc ion transmembrane transport	SLC39A14	IDA		Human	PMID:21917916
Biological Process	GO:0071577	zinc ion transmembrane transport	Slc39a14	IDA		Mouse	MGI:MGI:5295560\|PMID:21653899
Biological Process	GO:0006829	zinc ion transport	Slc39a14	IDA		Mouse	PMID:16950869

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.