Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Slc3a2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SLC3A2
- Mouse genes Slc3a2
- Rat genes Slc3a2
- Zfish genes slc3a2a,slc3a2b,zgc:158423
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc3a2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015173	aromatic amino acid transmembrane transporter activity	SLC3A2	IGI	UniProtKB:Q01650	Human	PMID:15589117
Molecular Function	GO:0045296	cadherin binding	SLC3A2	HDA		Human	PMID:25468996
Molecular Function	GO:0003725	double-stranded RNA binding	SLC3A2	IDA		Human	PMID:21266579
Molecular Function	GO:0015180	L-alanine transmembrane transporter activity	SLC3A2	IGI	UniProtKB:Q9UHI5	Human	PMID:10391915
Molecular Function	GO:0015190	L-leucine transmembrane transporter activity	SLC3A2	IGI	UniProtKB:Q9UHI5	Human	PMID:10391915
Molecular Function	GO:0015175	neutral L-amino acid transmembrane transporter activity	SLC3A2	IGI	UniProtKB:Q01650	Human	PMID:17197568
Molecular Function	GO:0015175	neutral L-amino acid transmembrane transporter activity	Slc3a2	IDA		Rat	PMID:9480885\|RGD:69887
Molecular Function	GO:0015175	neutral L-amino acid transmembrane transporter activity	Slc3a2	IDA		Rat	PMID:9726963\|RGD:634189
Molecular Function	GO:0015175	neutral L-amino acid transmembrane transporter activity	Slc3a2	IMP		Rat	PMID:9726963\|RGD:634189
Molecular Function	GO:0005515	protein binding	SLC3A2	IPI	UniProtKB:Q9N1R6	Human	PMID:10506149
Molecular Function	GO:0005515	protein binding	SLC3A2	IPI	UniProtKB:Q9N1Q4	Human	PMID:10631289
Molecular Function	GO:0005515	protein binding	SLC3A2	IPI	UniProtKB:Q8TBR7	Human	PMID:12270127
Molecular Function	GO:0005515	protein binding	SLC3A2	IPI	UniProtKB:O52302	Human	PMID:20374249
Molecular Function	GO:0005515	protein binding	SLC3A2	IPI	UniProtKB:O52302,UniProtKB:P07900,UniProtKB:P08238,UniProtKB:P62979	Human	PMID:20374249
Molecular Function	GO:0005515	protein binding	SLC3A2	IPI	UniProtKB:Q86VI4	Human	PMID:25998567
Molecular Function	GO:0005515	protein binding	SLC3A2	IPI	UniProtKB:O15354	Human	PMID:28298427
Molecular Function	GO:0005515	protein binding	SLC3A2	IPI	UniProtKB:P27958	Human	PMID:30341327
Molecular Function	GO:0005515	protein binding	SLC3A2	IPI	UniProtKB:Q01650	Human	PMID:30867591
Molecular Function	GO:0005515	protein binding	Slc3a2	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Molecular Function	GO:0005515	protein binding	Slc3a2	IPI	PR:P63115	Mouse	PMID:10734121
Molecular Function	GO:0003723	RNA binding	SLC3A2	HDA		Human	PMID:22658674
Cellular Component	GO:1990184	amino acid transport complex	SLC3A2	IDA		Human	PMID:30867591
Cellular Component	GO:0016324	apical plasma membrane	SLC3A2	IDA		Human	PMID:31791063
Cellular Component	GO:0016324	apical plasma membrane	Slc3a2	IDA		Rat	PMID:11095508\|RGD:30309922
Cellular Component	GO:0044225	apical pole of neuron	Slc3a2	IDA		Mouse	PMID:16399997
Cellular Component	GO:0009925	basal plasma membrane	Slc3a2	IDA		Rat	PMID:11095508\|RGD:30309922
Cellular Component	GO:0016323	basolateral plasma membrane	SLC3A2	IDA		Human	PMID:31791063
Cellular Component	GO:0009986	cell surface	SLC3A2	HDA		Human	PMID:19581412
Cellular Component	GO:0009986	cell surface	SLC3A2	IDA		Human	PMID:25063885
Cellular Component	GO:0005737	cytoplasm	Slc3a2	IDA		Rat	PMID:28339760\|RGD:151361118
Cellular Component	GO:0070062	extracellular exosome	SLC3A2	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	SLC3A2	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	SLC3A2	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	SLC3A2	HDA		Human	PMID:23533145
Cellular Component	GO:0016020	membrane	SLC3A2	HDA		Human	PMID:19946888
Cellular Component	GO:0043025	neuronal cell body	Slc3a2	IDA		Mouse	PMID:16399997
Cellular Component	GO:0005654	nucleoplasm	SLC3A2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	SLC3A2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	SLC3A2	IDA		Human	PMID:11311135
Cellular Component	GO:0005886	plasma membrane	SLC3A2	IDA		Human	PMID:11557028
Cellular Component	GO:0005886	plasma membrane	SLC3A2	IDA		Human	PMID:12225859
Cellular Component	GO:0005886	plasma membrane	SLC3A2	IDA		Human	PMID:12270127
Cellular Component	GO:0005886	plasma membrane	SLC3A2	IDA		Human	PMID:25998567
Cellular Component	GO:0005886	plasma membrane	SLC3A2	IDA		Human	PMID:23137377
Cellular Component	GO:0005886	plasma membrane	SLC3A2	IDA		Human	PMID:28112518
Cellular Component	GO:0005886	plasma membrane	Slc3a2	IDA		Mouse	MGI:MGI:1329273\|PMID:9915839
Cellular Component	GO:0005886	plasma membrane	Slc3a2	IDA		Rat	PMID:28339760\|RGD:151361118
Cellular Component	GO:0045202	synapse	Slc3a2	EXP		Mouse	PMID:24534009
Cellular Component	GO:0045202	synapse	Slc3a2	IDA		Mouse	PMID:24534009
Biological Process	GO:0042149	cellular response to glucose starvation	Slc3a2	IEP		Rat	PMID:22185814\|RGD:151361127
Biological Process	GO:0015818	isoleucine transport	SLC3A2	IDA		Human	PMID:11311135
Biological Process	GO:0015818	isoleucine transport	SLC3A2	IDA		Human	PMID:11557028
Biological Process	GO:1904273	L-alanine import across plasma membrane	SLC3A2	IGI	UniProtKB:Q9UHI5	Human	PMID:10391915
Biological Process	GO:1902024	L-histidine transport	SLC3A2	IDA		Human	PMID:11557028
Biological Process	GO:1902024	L-histidine transport	SLC3A2	IDA		Human	PMID:9751058
Biological Process	GO:1902024	L-histidine transport	Slc3a2	IDA		Rat	PMID:10049700\|RGD:155230758
Biological Process	GO:1903801	L-leucine import across plasma membrane	SLC3A2	IGI	UniProtKB:Q9UHI5	Human	PMID:10391915
Biological Process	GO:1903801	L-leucine import across plasma membrane	Slc3a2	IDA		Rat	PMID:9480885\|RGD:69887
Biological Process	GO:0098713	leucine import across plasma membrane	SLC3A2	IGI	UniProtKB:Q01650	Human	PMID:17197568
Biological Process	GO:0015820	leucine transport	SLC3A2	IDA		Human	PMID:10574970
Biological Process	GO:0015820	leucine transport	SLC3A2	IDA		Human	PMID:11557028
Biological Process	GO:0015820	leucine transport	SLC3A2	IDA		Human	PMID:11564694
Biological Process	GO:0015820	leucine transport	SLC3A2	IDA		Human	PMID:12225859
Biological Process	GO:0015820	leucine transport	SLC3A2	IDA		Human	PMID:15769744
Biological Process	GO:0015820	leucine transport	SLC3A2	IMP		Human	PMID:30341327
Biological Process	GO:0015820	leucine transport	SLC3A2	IDA		Human	PMID:9751058
Biological Process	GO:0015820	leucine transport	Slc3a2	IDA		Mouse	MGI:MGI:1329273\|PMID:9915839
Biological Process	GO:0015820	leucine transport	Slc3a2	IDA		Rat	PMID:10049700\|RGD:155230758
Biological Process	GO:0015820	leucine transport	Slc3a2	IDA		Rat	PMID:9726963\|RGD:634189
Biological Process	GO:0015821	methionine transport	SLC3A2	IDA		Human	PMID:11557028
Biological Process	GO:0015804	neutral amino acid transport	Slc3a2	IMP		Rat	PMID:9726963\|RGD:634189
Biological Process	GO:0042476	odontogenesis	Slc3a2	IEP		Rat	PMID:15027953\|RGD:151361134
Biological Process	GO:0015823	phenylalanine transport	SLC3A2	IDA		Human	PMID:10574970
Biological Process	GO:0015823	phenylalanine transport	SLC3A2	IDA		Human	PMID:11557028
Biological Process	GO:0015823	phenylalanine transport	SLC3A2	IDA		Human	PMID:11564694
Biological Process	GO:0015823	phenylalanine transport	SLC3A2	IGI	UniProtKB:Q01650	Human	PMID:15589117
Biological Process	GO:0015823	phenylalanine transport	SLC3A2	IDA		Human	PMID:9751058
Biological Process	GO:0015823	phenylalanine transport	Slc3a2	IDA		Rat	PMID:10049700\|RGD:155230758
Biological Process	GO:0015824	proline transport	SLC3A2	IDA		Human	PMID:10574970
Biological Process	GO:0060142	regulation of syncytium formation by plasma membrane fusion	slc3a2a	IGI	ZFIN:ZDB-MRPHLNO-120315-2,ZFIN:ZDB-MRPHLNO-120315-3,ZFIN:ZDB-MRPHLNO-120315-4,ZFIN:ZDB-MRPHLNO-120319-1	Zfish	PMID:22331904
Biological Process	GO:0060142	regulation of syncytium formation by plasma membrane fusion	slc3a2b	IGI	ZFIN:ZDB-MRPHLNO-120315-2,ZFIN:ZDB-MRPHLNO-120315-3,ZFIN:ZDB-MRPHLNO-120315-4,ZFIN:ZDB-MRPHLNO-120319-1	Zfish	PMID:22331904
Biological Process	GO:0043330	response to exogenous dsRNA	SLC3A2	IMP		Human	PMID:21266579
Biological Process	GO:0014850	response to muscle activity	Slc3a2	IEP		Rat	PMID:24016666\|RGD:151361119
Biological Process	GO:0070327	thyroid hormone transport	SLC3A2	IDA		Human	PMID:11564694
Biological Process	GO:0015827	tryptophan transport	SLC3A2	IDA		Human	PMID:10574970
Biological Process	GO:0015827	tryptophan transport	SLC3A2	IDA		Human	PMID:11557028
Biological Process	GO:0015827	tryptophan transport	SLC3A2	IDA		Human	PMID:11564694
Biological Process	GO:0015827	tryptophan transport	Slc3a2	IDA		Rat	PMID:10049700\|RGD:155230758
Biological Process	GO:0015827	tryptophan transport	Slc3a2	IDA		Rat	PMID:12614332\|RGD:155230770
Biological Process	GO:0015828	tyrosine transport	SLC3A2	IDA		Human	PMID:11557028
Biological Process	GO:0015828	tyrosine transport	SLC3A2	IDA		Human	PMID:11564694
Biological Process	GO:0015829	valine transport	SLC3A2	IDA		Human	PMID:11557028
Biological Process	GO:0046718	viral entry into host cell	SLC3A2	IMP		Human	PMID:30341327

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.