Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Slc4a1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SLC4A1
- Mouse genes Slc4a1
- Rat genes Slc4a1
- Zfish genes slc4a1a,slc4a1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc4a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Slc4a1	IPI	RGD:2026	Rat	PMID:12898519\|RGD:1598723
Molecular Function	GO:0030506	ankyrin binding	SLC4A1	IPI	UniProtKB:P16157	Human	PMID:379653
Molecular Function	GO:0030506	ankyrin binding	Slc4a1	IPI	PR:Q02357	Mouse	PMID:17715300
Molecular Function	GO:0015106	bicarbonate transmembrane transporter activity	SLC4A1	IDA		Human	PMID:24121512
Molecular Function	GO:0015106	bicarbonate transmembrane transporter activity	Slc4a1	IDA		Mouse	PMID:23878365
Molecular Function	GO:0015106	bicarbonate transmembrane transporter activity	slc4a1b	IMP	ZFIN:ZDB-MRPHLNO-110216-8	Zfish	PMID:21123736
Molecular Function	GO:0015106	bicarbonate transmembrane transporter activity	slc4a1b	IMP	ZFIN:ZDB-GENO-080903-9	Zfish	PMID:23071446
Molecular Function	GO:0015108	chloride transmembrane transporter activity	Slc4a1	IDA		Mouse	MGI:MGI:3850313\|PMID:17690150
Molecular Function	GO:0140900	chloride:bicarbonate antiporter activity	SLC4A1	IDA		Human	PMID:28387307
Molecular Function	GO:0019899	enzyme binding	Slc4a1	IPI	RGD:1315034	Rat	PMID:17652430\|RGD:9999376
Molecular Function	GO:0019899	enzyme binding	Slc4a1	IPI	RGD:2661	Rat	PMID:20980406\|RGD:10450535
Molecular Function	GO:0030492	hemoglobin binding	Slc4a1	IDA		Mouse	PMID:22452706
Molecular Function	GO:0005515	protein binding	SLC4A1	IPI	UniProtKB:P11171	Human	PMID:16669616
Molecular Function	GO:0005515	protein binding	SLC4A1	IPI	UniProtKB:P02724	Human	PMID:19438409
Molecular Function	GO:0005515	protein binding	SLC4A1	IPI	UniProtKB:P46406	Human	PMID:20980406
Molecular Function	GO:0005515	protein binding	SLC4A1	IPI	UniProtKB:Q27744	Human	PMID:2204832
Molecular Function	GO:0005515	protein binding	SLC4A1	IPI	UniProtKB:P02724	Human	PMID:23219802
Molecular Function	GO:0005515	protein binding	SLC4A1	IPI	UniProtKB:P27105	Human	PMID:23219802
Molecular Function	GO:0005515	protein binding	SLC4A1	IPI	UniProtKB:P05026	Human	PMID:25012180
Molecular Function	GO:0005515	protein binding	SLC4A1	IPI	UniProtKB:Q8IV31	Human	PMID:26049106
Molecular Function	GO:0005515	protein binding	SLC4A1	IPI	UniProtKB:A5K5E5	Human	PMID:26823170
Molecular Function	GO:0005515	protein binding	SLC4A1	IPI	UniProtKB:P27105	Human	PMID:28387307
Molecular Function	GO:0005515	protein binding	SLC4A1	IPI	UniProtKB:O95393	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC4A1	IPI	UniProtKB:Q08AM2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC4A1	IPI	UniProtKB:Q9BXR6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC4A1	IPI	UniProtKB:Q9H2L4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Slc4a1	IPI	PR:Q03958	Mouse	PMID:11591653
Molecular Function	GO:0005515	protein binding	slc4a1a	IPI	ZFIN:ZDB-GENE-030130-1	Zfish	PMID:17569566
Molecular Function	GO:0042803	protein homodimerization activity	SLC4A1	IPI	UniProtKB:P02730	Human	PMID:379653
Molecular Function	GO:0044877	protein-containing complex binding	Slc4a1	IDA		Rat	PMID:20946910\|RGD:10450736
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	SLC4A1	IDA		Human	PMID:14734552
Molecular Function	GO:0005452	solute:inorganic anion antiporter activity	SLC4A1	IDA		Human	PMID:24121512
Molecular Function	GO:0022857	transmembrane transporter activity	slc4a1b	IMP	ZFIN:ZDB-GENO-080903-9	Zfish	PMID:23071446
Cellular Component	GO:0016323	basolateral plasma membrane	SLC4A1	IDA		Human	PMID:12539048
Cellular Component	GO:0016323	basolateral plasma membrane	SLC4A1	IDA		Human	PMID:14734552
Cellular Component	GO:0016323	basolateral plasma membrane	Slc4a1	IDA		Mouse	MGI:MGI:3607625\|PMID:16077082
Cellular Component	GO:0016323	basolateral plasma membrane	Slc4a1	IDA		Mouse	MGI:MGI:3710722\|PMID:12388412
Cellular Component	GO:0016323	basolateral plasma membrane	Slc4a1	IDA		Rat	PMID:10600930\|RGD:13208945
Cellular Component	GO:0016323	basolateral plasma membrane	Slc4a1	IDA		Rat	PMID:16144966\|RGD:8554685
Cellular Component	GO:0016323	basolateral plasma membrane	Slc4a1	IDA		Rat	PMID:16352747\|RGD:8553330
Cellular Component	GO:0016323	basolateral plasma membrane	Slc4a1	IDA		Rat	PMID:17804457\|RGD:8554499
Cellular Component	GO:0016323	basolateral plasma membrane	Slc4a1	IDA		Rat	PMID:9596071\|RGD:9999378
Cellular Component	GO:0072562	blood microparticle	SLC4A1	HDA		Human	PMID:22516433
Cellular Component	GO:0009986	cell surface	Slc4a1	IDA		Rat	PMID:20114059\|RGD:10450741
Cellular Component	GO:0030863	cortical cytoskeleton	SLC4A1	IDA		Human	PMID:16669616
Cellular Component	GO:0030863	cortical cytoskeleton	Slc4a1	IDA		Mouse	PMID:18723693
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	Slc4a1	IDA		Mouse	PMID:17715300
Cellular Component	GO:0070062	extracellular exosome	SLC4A1	HDA		Human	PMID:19056867
Cellular Component	GO:0014704	intercalated disc	Slc4a1	IDA		Rat	PMID:12898519\|RGD:1598723
Cellular Component	GO:0016020	membrane	Slc4a1	IDA		Mouse	MGI:MGI:3850313\|PMID:17690150
Cellular Component	GO:0005886	plasma membrane	SLC4A1	IDA		Human	PMID:24121512
Cellular Component	GO:0005886	plasma membrane	SLC4A1	IDA		Human	PMID:379653
Cellular Component	GO:0005886	plasma membrane	Slc4a1	IDA		Mouse	PMID:23878365
Cellular Component	GO:0005886	plasma membrane	Slc4a1	IDA		Mouse	PMID:34354145
Cellular Component	GO:0005886	plasma membrane	Slc4a1	IDA		Rat	PMID:24289085\|RGD:10450522
Cellular Component	GO:0030018	Z disc	Slc4a1	IDA		Rat	PMID:12898519\|RGD:1598723
Biological Process	GO:0015701	bicarbonate transport	SLC4A1	IDA		Human	PMID:24121512
Biological Process	GO:0015701	bicarbonate transport	Slc4a1	IDA		Mouse	PMID:23878365
Biological Process	GO:0015701	bicarbonate transport	slc4a1b	IMP	ZFIN:ZDB-GENO-080903-9	Zfish	PMID:23071446\|ZFIN:ZDB-PUB-121019-40
Biological Process	GO:0007596	blood coagulation	Slc4a1	IMP	MGI:MGI:1857140	Mouse	PMID:9716609
Biological Process	GO:0070509	calcium ion import	slc4a1b	IMP	ZFIN:ZDB-MRPHLNO-110216-8	Zfish	PMID:25679789
Biological Process	GO:1902476	chloride transmembrane transport	SLC4A1	IDA		Human	PMID:14734552
Biological Process	GO:0006821	chloride transport	Slc4a1	IDA		Mouse	MGI:MGI:3850313\|PMID:17690150
Biological Process	GO:0007623	circadian rhythm	Slc4a1	IEP		Rat	PMID:21903759\|RGD:10450532
Biological Process	GO:0035162	embryonic hemopoiesis	slc4a1a	IMP	ZFIN:ZDB-GENO-101220-3	Zfish	PMID:9007251
Biological Process	GO:0035162	embryonic hemopoiesis	slc4a1a	IMP	ZFIN:ZDB-GENO-980202-1080	Zfish	PMID:9007251
Biological Process	GO:0048821	erythrocyte development	Slc4a1	IMP	MGI:MGI:3834176	Mouse	PMID:17715300
Biological Process	GO:0030218	erythrocyte differentiation	slc4a1a	IMP	ZFIN:ZDB-GENO-980202-1080	Zfish	PMID:14608381
Biological Process	GO:0030218	erythrocyte differentiation	slc4a1a	IMP	ZFIN:ZDB-GENO-100511-5	Zfish	PMID:19672293
Biological Process	GO:0006820	monoatomic anion transport	slc4a1a	IDA		Zfish	PMID:16150548
Biological Process	GO:1904539	negative regulation of glycolytic process through fructose-6-phosphate	Slc4a1	IMP		Mouse	PMID:18698006
Biological Process	GO:0051354	negative regulation of oxidoreductase activity	Slc4a1	IMP		Mouse	PMID:18698006
Biological Process	GO:0035811	negative regulation of urine volume	Slc4a1	IMP	MGI:MGI:1857140	Mouse	PMID:17409310
Biological Process	GO:0045852	pH elevation	Slc4a1	IMP	MGI:MGI:1857140	Mouse	PMID:17409310
Biological Process	GO:0017121	plasma membrane phospholipid scrambling	Slc4a1	IMP	MGI:MGI:1857140	Mouse	PMID:9716609
Biological Process	GO:0042102	positive regulation of T cell proliferation	Slc4a1	IDA		Rat	PMID:12165075\|RGD:10450475
Biological Process	GO:0072659	protein localization to plasma membrane	Slc4a1	IMP	MGI:MGI:2441657	Mouse	PMID:18698006
Biological Process	GO:0072659	protein localization to plasma membrane	Slc4a1	IMP		Mouse	PMID:18698006
Biological Process	GO:0010447	response to acidic pH	Slc4a1	IEP		Rat	PMID:10600930\|RGD:13208945
Biological Process	GO:0014823	response to activity	Slc4a1	IDA		Rat	PMID:24289085\|RGD:10450522
Biological Process	GO:0010446	response to alkaline pH	Slc4a1	IEP		Rat	PMID:10600930\|RGD:13208945
Biological Process	GO:0046685	response to arsenic-containing substance	Slc4a1	IDA		Rat	PMID:20946910\|RGD:10450736
Biological Process	GO:0010037	response to carbon dioxide	Slc4a1	IDA		Rat	PMID:15075205\|RGD:10450756
Biological Process	GO:0042542	response to hydrogen peroxide	Slc4a1	IDA		Rat	PMID:20946910\|RGD:10450736
Biological Process	GO:0031667	response to nutrient levels	Slc4a1	IEP		Rat	PMID:21903759\|RGD:10450532
Biological Process	GO:0009414	response to water deprivation	Slc4a1	IEP		Rat	PMID:15284286\|RGD:10450755
Biological Process	GO:0055085	transmembrane transport	slc4a1b	IMP	ZFIN:ZDB-GENO-080903-9	Zfish	PMID:23071446\|ZFIN:ZDB-PUB-121019-40

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.