Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Slc5a1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SLC5A1
- Mouse genes Slc5a1
- Rat genes Slc5a1
- Zfish genes slc5a1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc5a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015151	alpha-glucoside transmembrane transporter activity	SLC5A1	IMP		Human	PMID:17130520
Molecular Function	GO:0015151	alpha-glucoside transmembrane transporter activity	SLC5A1	IDA		Human	PMID:20980548
Molecular Function	GO:0055056	D-glucose transmembrane transporter activity	SLC5A1	IDA		Human	PMID:20980548
Molecular Function	GO:0015371	galactose:sodium symporter activity	SLC5A1	IDA		Human	PMID:34880492
Molecular Function	GO:0015371	galactose:sodium symporter activity	SLC5A1	IDA		Human	PMID:35077764
Molecular Function	GO:0005355	glucose transmembrane transporter activity	SLC5A1	IDA		Human	PMID:26945065
Molecular Function	GO:0005355	glucose transmembrane transporter activity	Slc5a1	IMP		Mouse	PMID:10997927
Molecular Function	GO:0005412	glucose:sodium symporter activity	SLC5A1	IDA		Human	PMID:20980548
Molecular Function	GO:0005412	glucose:sodium symporter activity	SLC5A1	IDA		Human	PMID:34880492
Molecular Function	GO:0005412	glucose:sodium symporter activity	SLC5A1	IDA		Human	PMID:35077764
Molecular Function	GO:0005412	glucose:sodium symporter activity	SLC5A1	IDA		Human	PMID:8563765
Molecular Function	GO:0005412	glucose:sodium symporter activity	SLC5A1	IDA		Human	PMID:8836035
Molecular Function	GO:0005412	glucose:sodium symporter activity	Slc5a1	IDA		Mouse	MGI:MGI:5433249\|PMID:22124465
Molecular Function	GO:0005412	glucose:sodium symporter activity	Slc5a1	IDA		Rat	PMID:15829715\|RGD:1624261
Molecular Function	GO:0005515	protein binding	SLC5A1	IPI	UniProtKB:P00533	Human	PMID:18455122
Molecular Function	GO:0005372	water transmembrane transporter activity	SLC5A1	IDA		Human	PMID:14695256
Molecular Function	GO:0005372	water transmembrane transporter activity	SLC5A1	IDA		Human	PMID:26945065
Molecular Function	GO:0005372	water transmembrane transporter activity	SLC5A1	IDA		Human	PMID:34880492
Cellular Component	GO:0016324	apical plasma membrane	SLC5A1	IDA		Human	PMID:12773314
Cellular Component	GO:0016324	apical plasma membrane	Slc5a1	IDA		Mouse	MGI:MGI:5433249\|PMID:22124465
Cellular Component	GO:0016324	apical plasma membrane	Slc5a1	IDA		Mouse	PMID:1702069
Cellular Component	GO:0016324	apical plasma membrane	Slc5a1	IDA		Rat	PMID:11831390\|RGD:730194
Cellular Component	GO:0016324	apical plasma membrane	Slc5a1	IDA		Rat	PMID:14986005\|RGD:1579739
Cellular Component	GO:0005903	brush border	Slc5a1	IDA		Mouse	PMID:15601832
Cellular Component	GO:0031526	brush border membrane	Slc5a1	IDA		Rat	PMID:17272350\|RGD:2308883
Cellular Component	GO:0031526	brush border membrane	Slc5a1	IDA		Rat	PMID:14986005\|RGD:1579739
Cellular Component	GO:0005911	cell-cell junction	Slc5a1	IDA		Rat	PMID:17090404\|RGD:1624247
Cellular Component	GO:0005769	early endosome	SLC5A1	IDA		Human	PMID:12773314
Cellular Component	GO:0070062	extracellular exosome	SLC5A1	HDA		Human	PMID:19056867
Cellular Component	GO:0043229	intracellular organelle	Slc5a1	IDA		Rat	PMID:14986005\|RGD:1579739
Cellular Component	GO:0048471	perinuclear region of cytoplasm	SLC5A1	IDA		Human	PMID:12773314
Cellular Component	GO:0005886	plasma membrane	SLC5A1	IDA		Human	PMID:26945065
Biological Process	GO:0000017	alpha-glucoside transport	SLC5A1	IMP		Human	PMID:17130520
Biological Process	GO:0000017	alpha-glucoside transport	SLC5A1	IDA		Human	PMID:20980548
Biological Process	GO:0098708	glucose import across plasma membrane	SLC5A1	IDA		Human	PMID:20980548
Biological Process	GO:0098708	glucose import across plasma membrane	SLC5A1	IGI	UniProtKB:P11166,UniProtKB:P11169	Human	PMID:23975336
Biological Process	GO:0098708	glucose import across plasma membrane	SLC5A1	IDA		Human	PMID:26945065
Biological Process	GO:1904659	glucose transmembrane transport	SLC5A1	IMP		Human	PMID:8563765
Biological Process	GO:1904659	glucose transmembrane transport	SLC5A1	IDA		Human	PMID:8836035
Biological Process	GO:1904659	glucose transmembrane transport	Slc5a1	IMP		Mouse	PMID:10997927
Biological Process	GO:0050892	intestinal absorption	Slc5a1	IDA		Mouse	PMID:15601832
Biological Process	GO:0001951	intestinal D-glucose absorption	Slc5a1	IMP		Mouse	MGI:MGI:5433249\|PMID:22124465
Biological Process	GO:0001656	metanephros development	Slc5a1	IMP		Mouse	PMID:10997927
Biological Process	GO:0032409	regulation of transporter activity	Slc5a1	IDA		Mouse	PMID:24595108
Biological Process	GO:0035623	renal glucose absorption	Slc5a1	IMP		Mouse	MGI:MGI:5433249\|PMID:22124465
Biological Process	GO:0010035	response to inorganic substance	SLC5A1	IDA		Human	PMID:10973981
Biological Process	GO:0098719	sodium ion import across plasma membrane	SLC5A1	IDA		Human	PMID:20980548
Biological Process	GO:0035377	transepithelial water transport	SLC5A1	IDA		Human	PMID:26945065
Biological Process	GO:0150104	transport across blood-brain barrier	SLC5A1	IGI	UniProtKB:P11166,UniProtKB:P11169	Human	PMID:23975336

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.