Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC5A7
  • Mouse genes Slc5a7
  • Rat genes Slc5a7
  • Zfish genes slc5a7a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc5a7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0033265	choline binding	Slc5a7	IDA		Mouse	PMID:17196556
Molecular Function	GO:0015220	choline transmembrane transporter activity	SLC5A7	IMP		Human	PMID:11068039
Molecular Function	GO:0015220	choline transmembrane transporter activity	Slc5a7	IMP		Mouse	MGI:MGI:3044863|PMID:15173594
Molecular Function	GO:0015220	choline transmembrane transporter activity	Slc5a7	IDA		Mouse	PMID:17196556
Molecular Function	GO:0015220	choline transmembrane transporter activity	Slc5a7	IMP		Rat	PMID:10649566|RGD:68853
Molecular Function	GO:0005307	choline:sodium symporter activity	SLC5A7	IMP		Human	PMID:12237312
Molecular Function	GO:0005515	protein binding	Slc5a7	IPI	UniProtKB:P05067	Mouse	MGI:MGI:3829124|PMID:17709753
Molecular Function	GO:0005515	protein binding	Slc5a7	IPI	UniProtKB:Q92503	Rat	PMID:17092608|RGD:10449518
Cellular Component	GO:0016324	apical plasma membrane	Slc5a7	IDA		Rat	PMID:12628461|RGD:9999384
Cellular Component	GO:0030424	axon	Slc5a7	IDA		Rat	PMID:11904763|RGD:1299242
Cellular Component	GO:0045334	clathrin-coated endocytic vesicle	Slc5a7	IDA		Rat	PMID:15953352|RGD:9999386
Cellular Component	GO:0030425	dendrite	Slc5a7	IDA		Rat	PMID:11904763|RGD:1299242
Cellular Component	GO:0005769	early endosome	Slc5a7	IDA		Rat	PMID:15953352|RGD:9999386
Cellular Component	GO:0016020	membrane	SLC5A7	IDA		Human	PMID:11027560
Cellular Component	GO:0031594	neuromuscular junction	SLC5A7	IDA		Human	PMID:27569547
Cellular Component	GO:0043025	neuronal cell body	Slc5a7	IDA		Mouse	PMID:17196556
Cellular Component	GO:0043204	perikaryon	Slc5a7	IDA		Rat	PMID:11904763|RGD:1299242
Cellular Component	GO:0005886	plasma membrane	SLC5A7	IDA		Human	PMID:12237312
Cellular Component	GO:0005886	plasma membrane	Slc5a7	IDA		Mouse	PMID:17196556
Cellular Component	GO:0044853	plasma membrane raft	Slc5a7	IDA		Rat	PMID:24127780|RGD:9999385
Cellular Component	GO:0045202	synapse	Slc5a7	IDA		Rat	PMID:11904763|RGD:1299242
Cellular Component	GO:0008021	synaptic vesicle	Slc5a7	IDA		Rat	PMID:20394050|RGD:9999388
Biological Process	GO:0008292	acetylcholine biosynthetic process	SLC5A7	IMP		Human	PMID:11068039
Biological Process	GO:0008292	acetylcholine biosynthetic process	Slc5a7	IMP	MGI:MGI:3045463	Mouse	PMID:15173594
Biological Process	GO:0008292	acetylcholine biosynthetic process	Slc5a7	IMP		Rat	PMID:10649566|RGD:68853
Biological Process	GO:0015871	choline transport	Slc5a7	IMP	MGI:MGI:3045463	Mouse	PMID:15173594
Biological Process	GO:0015871	choline transport	Slc5a7	IDA		Mouse	PMID:17196556
Biological Process	GO:0001701	in utero embryonic development	Slc5a7	IMP	MGI:MGI:4942035	Mouse	PMID:27996060
Biological Process	GO:0007274	neuromuscular synaptic transmission	Slc5a7	IMP	MGI:MGI:3045463	Mouse	PMID:15173594
Biological Process	GO:0007271	synaptic transmission, cholinergic	Slc5a7	IMP		Mouse	PMID:16162937
Biological Process	GO:0007271	synaptic transmission, cholinergic	Slc5a7	IMP	MGI:MGI:3045463	Mouse	PMID:15173594

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern