Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC6A11
  • Mouse genes Slc6a11
  • Rat genes Slc6a11
  • Zfish genes slc6a11a,slc6a11b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc6a11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005283	amino acid:sodium symporter activity	Slc6a11	IDA		Mouse	MGI:MGI:7275316|PMID:30270321
Molecular Function	GO:0005283	amino acid:sodium symporter activity	Slc6a11	IDA		Mouse	MGI:MGI:52213|PMID:8420981
Molecular Function	GO:0005332	gamma-aminobutyric acid:sodium:chloride symporter activity	SLC6A11	IDA		Human	PMID:7874447
Molecular Function	GO:0005332	gamma-aminobutyric acid:sodium:chloride symporter activity	Slc6a11	IDA		Mouse	MGI:MGI:7275316|PMID:30270321
Molecular Function	GO:0005332	gamma-aminobutyric acid:sodium:chloride symporter activity	Slc6a11	IDA		Mouse	MGI:MGI:52213|PMID:8420981
Molecular Function	GO:0005332	gamma-aminobutyric acid:sodium:chloride symporter activity	Slc6a11	IDA		Rat	PMID:1400419|RGD:727560
Molecular Function	GO:0005332	gamma-aminobutyric acid:sodium:chloride symporter activity	Slc6a11	IDA		Rat	PMID:1497897|RGD:729938
Molecular Function	GO:0008028	monocarboxylic acid transmembrane transporter activity	SLC6A11	IDA		Human	PMID:29175673
Molecular Function	GO:0042165	neurotransmitter binding	Slc6a11	IDA		Rat	PMID:1400419|RGD:727560
Molecular Function	GO:0005369	taurine:sodium symporter activity	Slc6a11	IDA		Mouse	MGI:MGI:52213|PMID:8420981
Cellular Component	GO:0042995	cell projection	Slc6a11	IDA		Rat	PMID:12898208|RGD:2316969
Cellular Component	GO:0005737	cytoplasm	Slc6a11	IDA		Rat	PMID:12898208|RGD:2316969
Cellular Component	GO:0098982	GABA-ergic synapse	Slc6a11	IDA		Rat	PMID:24368619|RGD:13702342
Cellular Component	GO:0098982	GABA-ergic synapse	Slc6a11	IDA		Rat	PMID:25120439|RGD:13702462
Cellular Component	GO:0016020	membrane	Slc6a11	IDA		Rat	PMID:16466645|RGD:2316966
Cellular Component	GO:0005886	plasma membrane	Slc6a11	IDA		Rat	PMID:8731228|RGD:152025522
Cellular Component	GO:0045211	postsynaptic membrane	Slc6a11	IDA		Rat	PMID:24368619|RGD:13702342
Cellular Component	GO:0042734	presynaptic membrane	Slc6a11	IDA		Rat	PMID:24368619|RGD:13702342
Cellular Component	GO:0042734	presynaptic membrane	Slc6a11	IDA		Rat	PMID:25120439|RGD:13702462
Cellular Component	GO:0045202	synapse	Slc6a11	EXP		Mouse	PMID:24534009
Cellular Component	GO:0045202	synapse	Slc6a11	IDA		Mouse	PMID:24534009
Biological Process	GO:0007420	brain development	Slc6a11	IEP		Rat	PMID:12898208|RGD:2316969
Biological Process	GO:0015718	monocarboxylic acid transport	SLC6A11	IDA		Human	PMID:29175673
Biological Process	GO:0006836	neurotransmitter transport	Slc6a11	IDA		Rat	PMID:1400419|RGD:727560
Biological Process	GO:0001504	neurotransmitter uptake	Slc6a11	IDA		Mouse	PMID:8420981
Biological Process	GO:0001504	neurotransmitter uptake	Slc6a11	IMP		Mouse	PMID:8420981
Biological Process	GO:0009410	response to xenobiotic stimulus	Slc6a11	IEP		Rat	PMID:17408599|RGD:1643196

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern