Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC6A7
  • Mouse genes Slc6a7
  • Rat genes Slc6a7
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc6a7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015193	L-proline transmembrane transporter activity	SLC6A7	IDA		Human	PMID:7651355
Molecular Function	GO:0015193	L-proline transmembrane transporter activity	Slc6a7	IDA		Mouse	PMID:19029042
Molecular Function	GO:0015193	L-proline transmembrane transporter activity	Slc6a7	IDA		Rat	PMID:10414958|RGD:152025513
Molecular Function	GO:0015193	L-proline transmembrane transporter activity	Slc6a7	IDA		Rat	PMID:1350201|RGD:633816
Molecular Function	GO:0005298	proline:sodium symporter activity	SLC6A7	IDA		Human	PMID:7651355
Molecular Function	GO:0005298	proline:sodium symporter activity	Slc6a7	IDA		Rat	PMID:10414958|RGD:152025513
Cellular Component	GO:0098978	glutamatergic synapse	Slc6a7	IDA		Rat	PMID:9870934|RGD:13702417
Cellular Component	GO:0042734	presynaptic membrane	Slc6a7	IDA		Rat	PMID:9870934|RGD:13702417
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Slc6a7	IDA		Rat	PMID:9870934|RGD:13702417
Cellular Component	GO:0045202	synapse	SLC6A7	EXP		Human	PMID:7651355
Cellular Component	GO:0045202	synapse	SLC6A7	IDA		Human	PMID:7651355
Cellular Component	GO:0045202	synapse	SLC6A7	IMP		Human	PMID:7651355
Cellular Component	GO:0045202	synapse	Slc6a7	EXP		Rat	PMID:6286882|RGD:155230706
Cellular Component	GO:0030672	synaptic vesicle membrane	Slc6a7	IDA		Rat	PMID:9870934|RGD:13702417
Biological Process	GO:1902475	L-alpha-amino acid transmembrane transport	Slc6a7	IDA		Mouse	MGI:MGI:3820712|PMID:19029042
Biological Process	GO:0015804	neutral amino acid transport	Slc6a7	IDA		Mouse	MGI:MGI:3820712|PMID:19029042
Biological Process	GO:0035524	proline transmembrane transport	Slc6a7	IDA		Mouse	PMID:19029042
Biological Process	GO:0015824	proline transport	SLC6A7	IDA		Human	PMID:7651355
Biological Process	GO:0015824	proline transport	Slc6a7	IDA		Rat	PMID:10414958|RGD:152025513
Biological Process	GO:0015824	proline transport	Slc6a7	IDA		Rat	PMID:1350201|RGD:633816
Biological Process	GO:0030163	protein catabolic process	SLC6A7	EXP		Human	PMID:7651355
Biological Process	GO:0030163	protein catabolic process	SLC6A7	IDA		Human	PMID:7651355
Biological Process	GO:0030163	protein catabolic process	SLC6A7	IMP		Human	PMID:7651355
Biological Process	GO:0030163	protein catabolic process	Slc6a7	EXP		Rat	PMID:6286882|RGD:155230706

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern