Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC6A9
  • Mouse genes Slc6a9
  • Rat genes Slc6a9
  • Zfish genes slc6a9
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc6a9

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015187	glycine transmembrane transporter activity	Slc6a9	IMP		Mouse	MGI:MGI:6450351|PMID:28495915
Molecular Function	GO:0015187	glycine transmembrane transporter activity	Slc6a9	IMP		Mouse	MGI:MGI:3044468|PMID:15159536
Molecular Function	GO:0015187	glycine transmembrane transporter activity	Slc6a9	IDA		Mouse	PMID:1618338
Molecular Function	GO:0015187	glycine transmembrane transporter activity	Slc6a9	IDA		Rat	PMID:12091465|RGD:30309946
Molecular Function	GO:0015187	glycine transmembrane transporter activity	slc6a9	IDA		Zfish	PMID:16014722
Molecular Function	GO:0015375	glycine:sodium symporter activity	Slc6a9	IDA		Mouse	MGI:MGI:49905|PMID:1618338
Molecular Function	GO:0015375	glycine:sodium symporter activity	Slc6a9	IDA		Rat	PMID:1534013|RGD:632882
Molecular Function	GO:0015375	glycine:sodium symporter activity	Slc6a9	IDA		Rat	PMID:16181645|RGD:151665718
Molecular Function	GO:0005515	protein binding	Slc6a9	IPI	UniProtKB:Q62824	Rat	PMID:16181645|RGD:151665718
Molecular Function	GO:0005515	protein binding	Slc6a9	IPI	UniProtKB:Q62825	Rat	PMID:16181645|RGD:151665718
Molecular Function	GO:0005515	protein binding	Slc6a9	IPI	UniProtKB:Q9NV70	Rat	PMID:16181645|RGD:151665718
Molecular Function	GO:0005515	protein binding	Slc6a9	IPI	UniProtKB:P31016	Rat	PMID:16271045|RGD:8554710
Cellular Component	GO:0016324	apical plasma membrane	SLC6A9	IDA		Human	PMID:11159884
Cellular Component	GO:0032279	asymmetric synapse	Slc6a9	IDA		Rat	PMID:15749988|RGD:13702293
Cellular Component	GO:0009925	basal plasma membrane	SLC6A9	IDA		Human	PMID:11159884
Cellular Component	GO:0016323	basolateral plasma membrane	SLC6A9	IDA		Human	PMID:11159884
Cellular Component	GO:0031045	dense core granule	Slc6a9	IDA		Rat	PMID:12091465|RGD:30309946
Cellular Component	GO:0005768	endosome	Slc6a9	IDA		Rat	PMID:12091465|RGD:30309946
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Slc6a9	IDA		Rat	PMID:15749988|RGD:13702293
Cellular Component	GO:0016328	lateral plasma membrane	SLC6A9	IDA		Human	PMID:11159884
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	Slc6a9	IDA		Rat	PMID:15749988|RGD:13702293
Cellular Component	GO:0005886	plasma membrane	Slc6a9	IDA		Mouse	PMID:17724084
Cellular Component	GO:0005886	plasma membrane	Slc6a9	IDA		Rat	PMID:16181645|RGD:151665718
Cellular Component	GO:0005886	plasma membrane	Slc6a9	IDA		Rat	PMID:12091465|RGD:30309946
Cellular Component	GO:0014069	postsynaptic density	Slc6a9	IDA		Rat	PMID:15749988|RGD:13702293
Cellular Component	GO:0045211	postsynaptic membrane	Slc6a9	IDA		Rat	PMID:15749988|RGD:13702293
Cellular Component	GO:0042734	presynaptic membrane	Slc6a9	IDA		Rat	PMID:15749988|RGD:13702293
Cellular Component	GO:0030672	synaptic vesicle membrane	Slc6a9	IDA		Rat	PMID:24036061|RGD:13702299
Biological Process	GO:1903804	glycine import across plasma membrane	Slc6a9	IMP		Mouse	MGI:MGI:6450351|PMID:28495915
Biological Process	GO:1903804	glycine import across plasma membrane	Slc6a9	IDA		Rat	PMID:12091465|RGD:30309946
Biological Process	GO:0061537	glycine secretion, neurotransmission	Slc6a9	IMP		Mouse	PMID:22988142
Biological Process	GO:0015816	glycine transport	Slc6a9	IMP		Mouse	MGI:MGI:2680877|PMID:14622582
Biological Process	GO:0015816	glycine transport	Slc6a9	IMP		Mouse	MGI:MGI:3044468|PMID:15159536
Biological Process	GO:0015816	glycine transport	Slc6a9	IDA		Mouse	PMID:1618338
Biological Process	GO:0015816	glycine transport	slc6a9	IMP	ZFIN:ZDB-GENO-980202-1422	Zfish	PMID:16014722
Biological Process	GO:0060080	inhibitory postsynaptic potential	slc6a9	IMP	ZFIN:ZDB-GENO-980202-1035	Zfish	PMID:18715895
Biological Process	GO:0007626	locomotory behavior	slc6a9	IMP	ZFIN:ZDB-MRPHLNO-050805-1	Zfish	PMID:16014722
Biological Process	GO:1904782	negative regulation of NMDA glutamate receptor activity	Slc6a9	IMP		Mouse	MGI:MGI:3044468|PMID:15159536
Biological Process	GO:0001504	neurotransmitter uptake	Slc6a9	IDA		Mouse	PMID:1618338
Biological Process	GO:0001504	neurotransmitter uptake	Slc6a9	IMP		Mouse	PMID:1618338
Biological Process	GO:0070455	positive regulation of heme biosynthetic process	Slc6a9	IMP		Mouse	MGI:MGI:6450351|PMID:28495915
Biological Process	GO:0046985	positive regulation of hemoglobin biosynthetic process	Slc6a9	IMP		Mouse	MGI:MGI:6450351|PMID:28495915
Biological Process	GO:0060092	regulation of synaptic transmission, glycinergic	Slc6a9	IMP		Mouse	MGI:MGI:2680877|PMID:14622582
Biological Process	GO:0060092	regulation of synaptic transmission, glycinergic	slc6a9	IMP	ZFIN:ZDB-GENO-980202-1035	Zfish	PMID:18715895

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern