Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC7A1
  • Mouse genes Slc7a1
  • Rat genes Slc7a1
  • Zfish genes slc7a1a,slc7a1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc7a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015171	amino acid transmembrane transporter activity	SLC7A1	IDA		Human	PMID:28684763
Molecular Function	GO:0015174	basic amino acid transmembrane transporter activity	SLC7A1	IDA		Human	PMID:11891586
Molecular Function	GO:0015174	basic amino acid transmembrane transporter activity	SLC7A1	IMP		Human	PMID:17197568
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	SLC7A1	IMP		Human	PMID:26449889
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	SLC7A1	IDA		Human	PMID:9174363
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	Slc7a1	IDA		Mouse	MGI:MGI:708000|PMID:9174363
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	Slc7a1	IDA		Mouse	MGI:MGI:59821|PMID:1652100
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	Slc7a1	IDA		Mouse	MGI:MGI:7310019|PMID:1908564
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	Slc7a1	IDA		Mouse	PMID:8195186
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	Slc7a1	IDA		Mouse	PMID:8385111
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	Slc7a1	IDA		Rat	PMID:17234578|RGD:1642930
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	Slc7a1	IMP		Rat	PMID:19712052|RGD:30309907
Molecular Function	GO:0005290	L-histidine transmembrane transporter activity	SLC7A1	IDA		Human	PMID:11591158
Molecular Function	GO:0015189	L-lysine transmembrane transporter activity	SLC7A1	IDA		Human	PMID:10485994
Molecular Function	GO:0015189	L-lysine transmembrane transporter activity	Slc7a1	IDA		Mouse	MGI:MGI:59821|PMID:1652100
Molecular Function	GO:0015189	L-lysine transmembrane transporter activity	Slc7a1	IDA		Mouse	MGI:MGI:7310019|PMID:1908564
Molecular Function	GO:0000064	L-ornithine transmembrane transporter activity	Slc7a1	IDA		Mouse	MGI:MGI:59821|PMID:1652100
Molecular Function	GO:0000064	L-ornithine transmembrane transporter activity	Slc7a1	IDA		Mouse	MGI:MGI:7310019|PMID:1908564
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q969F0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q9BSR8	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:O14894	Human	PMID:30956113
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:A5PKU2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:O00258	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:O14735	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:O14880	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:O15243	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:O60242	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:O95214	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:P02652	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:P07357	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:P11912	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:P13236	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:P16278	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:P21964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:P25942	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:P27352	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:P27449	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:P43378	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:P50876	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:P54315	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:P55061	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q05940	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q13586	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q15436	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q5J8X5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q5TGU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q8N138	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q8N3T1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q8NHW4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q8TAZ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q969F0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q96D05-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q96HH6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q96JF0-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q96Q45-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q9BQ51	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q9BRI3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q9BSE4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q9BSR8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q9BV81	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q9GZY8-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q9HA82	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q9NP94	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q9NRQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q9NTJ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q9NUM3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q9NWF4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q9NY72	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A1	IPI	UniProtKB:Q9Y6G1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Slc7a1	IPI	UniProtKB:P16460	Mouse	MGI:MGI:5305859|PMID:22081021
Molecular Function	GO:0001618	virus receptor activity	Slc7a1	IDA		Mouse	MGI:MGI:7310019|PMID:1908564
Cellular Component	GO:0016324	apical plasma membrane	SLC7A1	IDA		Human	PMID:31791063
Cellular Component	GO:0016324	apical plasma membrane	Slc7a1	IDA		Rat	PMID:19712052|RGD:30309907
Cellular Component	GO:0016324	apical plasma membrane	Slc7a1	IDA		Rat	PMID:29247719|RGD:30309915
Cellular Component	GO:0009925	basal plasma membrane	Slc7a1	IDA		Rat	PMID:19712052|RGD:30309907
Cellular Component	GO:0009925	basal plasma membrane	Slc7a1	IDA		Rat	PMID:29247719|RGD:30309915
Cellular Component	GO:0016323	basolateral plasma membrane	SLC7A1	IDA		Human	PMID:11891586
Cellular Component	GO:0016323	basolateral plasma membrane	SLC7A1	IDA		Human	PMID:31791063
Cellular Component	GO:0016020	membrane	SLC7A1	HDA		Human	PMID:19946888
Cellular Component	GO:0005886	plasma membrane	SLC7A1	IDA		Human	PMID:28112518
Cellular Component	GO:0005886	plasma membrane	Slc7a1	IDA		Rat	PMID:17234578|RGD:1642930
Cellular Component	GO:0032991	protein-containing complex	SLC7A1	IDA		Human	PMID:28246125
Biological Process	GO:0089718	amino acid import across plasma membrane	SLC7A1	IDA		Human	PMID:28684763
Biological Process	GO:0015807	L-amino acid transport	SLC7A1	IDA		Human	PMID:28684763
Biological Process	GO:0097638	L-arginine import across plasma membrane	Slc7a1	IMP		Rat	PMID:19712052|RGD:30309907
Biological Process	GO:1903826	L-arginine transmembrane transport	SLC7A1	IMP		Human	PMID:26449889
Biological Process	GO:1903826	L-arginine transmembrane transport	SLC7A1	IDA		Human	PMID:9174363
Biological Process	GO:1903826	L-arginine transmembrane transport	Slc7a1	IDA		Mouse	MGI:MGI:708000|PMID:9174363
Biological Process	GO:1903826	L-arginine transmembrane transport	Slc7a1	IDA		Mouse	MGI:MGI:7310019|PMID:1908564
Biological Process	GO:1903826	L-arginine transmembrane transport	Slc7a1	IDA		Mouse	MGI:MGI:59821|PMID:1652100
Biological Process	GO:1903826	L-arginine transmembrane transport	Slc7a1	IDA		Mouse	PMID:8195186
Biological Process	GO:1903826	L-arginine transmembrane transport	Slc7a1	IDA		Mouse	PMID:8385111
Biological Process	GO:1903826	L-arginine transmembrane transport	Slc7a1	IMP		Rat	PMID:17234578|RGD:1642930
Biological Process	GO:1903810	L-histidine import across plasma membrane	SLC7A1	IDA		Human	PMID:11591158
Biological Process	GO:1903352	L-ornithine transmembrane transport	Slc7a1	IDA		Mouse	MGI:MGI:7310019|PMID:1908564
Biological Process	GO:1903352	L-ornithine transmembrane transport	Slc7a1	IDA		Mouse	MGI:MGI:59821|PMID:1652100
Biological Process	GO:0015819	lysine transport	SLC7A1	IDA		Human	PMID:11891586
Biological Process	GO:0015822	ornithine transport	SLC7A1	IMP		Human	PMID:17197568
Biological Process	GO:0042102	positive regulation of T cell proliferation	SLC7A1	IMP		Human	PMID:26449889
Biological Process	GO:0032006	regulation of TOR signaling	Slc7a1	IMP		Rat	PMID:17234578|RGD:1642930

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern