Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC7A3
  • Mouse genes Slc7a3
  • Rat genes Slc7a3
  • Zfish genes slc7a3a,slc7a3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc7a3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015174	basic amino acid transmembrane transporter activity	Slc7a3	IDA		Mouse	PMID:9334265
Molecular Function	GO:0015174	basic amino acid transmembrane transporter activity	Slc7a3	IDA		Rat	PMID:9079705|RGD:68219
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	SLC7A3	IDA		Human	PMID:11591158
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	Slc7a3	IDA		Mouse	PMID:9334265
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	Slc7a3	IDA		Rat	PMID:17234578|RGD:1642930
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	Slc7a3	IDA		Rat	PMID:9079705|RGD:68219
Molecular Function	GO:0015189	L-lysine transmembrane transporter activity	SLC7A3	IDA		Human	PMID:11591158
Molecular Function	GO:0015189	L-lysine transmembrane transporter activity	Slc7a3	IDA		Mouse	PMID:9334265
Molecular Function	GO:0015189	L-lysine transmembrane transporter activity	Slc7a3	IDA		Rat	PMID:9079705|RGD:68219
Molecular Function	GO:0000064	L-ornithine transmembrane transporter activity	SLC7A3	IDA		Human	PMID:11591158
Molecular Function	GO:0000064	L-ornithine transmembrane transporter activity	Slc7a3	IDA		Rat	PMID:9079705|RGD:68219
Molecular Function	GO:0005515	protein binding	SLC7A3	IPI	UniProtKB:Q14973	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SLC7A3	IPI	UniProtKB:Q96Q45-2	Human	PMID:32296183
Cellular Component	GO:0005886	plasma membrane	SLC7A3	IDA		Human	PMID:11591158
Cellular Component	GO:0005886	plasma membrane	SLC7A3	IDA		Human	PMID:16332251
Cellular Component	GO:0005886	plasma membrane	Slc7a3	IDA		Rat	PMID:17234578|RGD:1642930
Biological Process	GO:1990822	basic amino acid transmembrane transport	Slc7a3	IDA		Mouse	MGI:MGI:1098061|PMID:9334265
Biological Process	GO:0006631	fatty acid metabolic process	slc7a3a	IMP	ZFIN:ZDB-GENO-180130-1	Zfish	PMID:25130427
Biological Process	GO:0097638	L-arginine import across plasma membrane	SLC7A3	IDA		Human	PMID:11591158
Biological Process	GO:1903826	L-arginine transmembrane transport	Slc7a3	IDA		Mouse	PMID:9334265
Biological Process	GO:1903826	L-arginine transmembrane transport	Slc7a3	IMP		Rat	PMID:17234578|RGD:1642930
Biological Process	GO:1903826	L-arginine transmembrane transport	Slc7a3	IDA		Rat	PMID:9079705|RGD:68219
Biological Process	GO:0097639	L-lysine import across plasma membrane	SLC7A3	IDA		Human	PMID:11591158
Biological Process	GO:1903401	L-lysine transmembrane transport	Slc7a3	IDA		Mouse	MGI:MGI:1098061|PMID:9334265
Biological Process	GO:0097640	L-ornithine import across plasma membrane	SLC7A3	IDA		Human	PMID:11591158
Biological Process	GO:0015819	lysine transport	Slc7a3	IDA		Rat	PMID:9079705|RGD:68219
Biological Process	GO:0015822	ornithine transport	Slc7a3	IDA		Rat	PMID:9079705|RGD:68219
Biological Process	GO:0032006	regulation of TOR signaling	Slc7a3	IMP		Rat	PMID:17234578|RGD:1642930
Biological Process	GO:0006641	triglyceride metabolic process	slc7a3a	IMP	ZFIN:ZDB-GENO-180130-1	Zfish	PMID:25130427

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern