Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC8B1
  • Mouse genes Slc8b1
  • Rat genes Slc8b1
  • Zfish genes slc8b1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc8b1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005432	calcium:sodium antiporter activity	SLC8B1	IMP		Human	PMID:20018762
Molecular Function	GO:0005432	calcium:sodium antiporter activity	SLC8B1	IDA		Human	PMID:23056385
Molecular Function	GO:0005432	calcium:sodium antiporter activity	SLC8B1	IDA		Human	PMID:24898248
Molecular Function	GO:0005432	calcium:sodium antiporter activity	SLC8B1	IDA		Human	PMID:28219928
Molecular Function	GO:0005432	calcium:sodium antiporter activity	Slc8b1	IDA		Mouse	MGI:MGI:4420691|PMID:20018762
Molecular Function	GO:0005432	calcium:sodium antiporter activity	Slc8b1	IMP		Mouse	MGI:MGI:5902863|PMID:28445457
Molecular Function	GO:0005432	calcium:sodium antiporter activity	Slc8b1	IDA		Mouse	PMID:14625281
Molecular Function	GO:0086038	calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential	Slc8b1	IMP		Mouse	MGI:MGI:5902863|PMID:28445457
Molecular Function	GO:0086038	calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential	Slc8b1	IMP		Mouse	MGI:MGI:5902676|PMID:24067497
Molecular Function	GO:0042802	identical protein binding	Slc8b1	IDA		Rat	PMID:20018762|RGD:9685493
Molecular Function	GO:0042803	protein homodimerization activity	SLC8B1	IPI	UniProtKB:Q6J4K2	Human	PMID:20018762
Molecular Function	GO:0042803	protein homodimerization activity	Slc8b1	IPI	UniProtKB:Q925Q3	Mouse	MGI:MGI:4420691|PMID:20018762
Molecular Function	GO:0042803	protein homodimerization activity	Slc8b1	IPI	UniProtKB:Q6AXS0	Rat	PMID:20018762|RGD:9685493
Cellular Component	GO:0030061	mitochondrial crista	SLC8B1	IDA		Human	PMID:20018762
Cellular Component	GO:0030061	mitochondrial crista	Slc8b1	IDA		Rat	PMID:20018762|RGD:9685493
Cellular Component	GO:0005743	mitochondrial inner membrane	Slc8b1	IDA		Rat	PMID:14625281|RGD:8553818
Cellular Component	GO:0031966	mitochondrial membrane	SLC8B1	IDA		Human	PMID:23056385
Cellular Component	GO:0005739	mitochondrion	Slc8b1	IDA		Mouse	MGI:MGI:5902676|PMID:24067497
Cellular Component	GO:0005739	mitochondrion	Slc8b1	IDA		Mouse	PMID:20018762
Cellular Component	GO:0005739	mitochondrion	Slc8b1	IDA		Rat	PMID:20018762|RGD:9685493
Cellular Component	GO:0005886	plasma membrane	Slc8b1	IDA		Mouse	PMID:14625281
Cellular Component	GO:0042383	sarcolemma	Slc8b1	IDA		Rat	PMID:14625281|RGD:8553818
Biological Process	GO:0099093	calcium export from the mitochondrion	SLC8B1	IDA		Human	PMID:24898248
Biological Process	GO:0099093	calcium export from the mitochondrion	Slc8b1	IMP		Mouse	MGI:MGI:5902863|PMID:28445457
Biological Process	GO:0099093	calcium export from the mitochondrion	Slc8b1	IMP		Mouse	MGI:MGI:5902676|PMID:24067497
Biological Process	GO:0070588	calcium ion transmembrane transport	Slc8b1	IDA		Mouse	PMID:14625281
Biological Process	GO:0042593	glucose homeostasis	SLC8B1	IDA		Human	PMID:23056385
Biological Process	GO:0051560	mitochondrial calcium ion homeostasis	SLC8B1	IMP		Human	PMID:20018762
Biological Process	GO:0051560	mitochondrial calcium ion homeostasis	SLC8B1	IDA		Human	PMID:24898248
Biological Process	GO:0051560	mitochondrial calcium ion homeostasis	Slc8b1	IMP		Mouse	MGI:MGI:5902863|PMID:28445457
Biological Process	GO:0051560	mitochondrial calcium ion homeostasis	Slc8b1	IDA		Mouse	MGI:MGI:4420691|PMID:20018762
Biological Process	GO:0006851	mitochondrial calcium ion transmembrane transport	SLC8B1	IMP		Human	PMID:20018762
Biological Process	GO:0006851	mitochondrial calcium ion transmembrane transport	SLC8B1	IDA		Human	PMID:23056385
Biological Process	GO:0006851	mitochondrial calcium ion transmembrane transport	SLC8B1	IDA		Human	PMID:24898248
Biological Process	GO:0006851	mitochondrial calcium ion transmembrane transport	Slc8b1	IMP		Mouse	MGI:MGI:5902863|PMID:28445457
Biological Process	GO:0006851	mitochondrial calcium ion transmembrane transport	Slc8b1	IDA		Mouse	PMID:20018762
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	SLC8B1	IMP		Human	PMID:20018762
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	Slc8b1	IDA		Mouse	MGI:MGI:4420691|PMID:20018762
Biological Process	GO:0050796	regulation of insulin secretion	SLC8B1	IDA		Human	PMID:23056385
Biological Process	GO:1901623	regulation of lymphocyte chemotaxis	Slc8b1	IMP		Mouse	MGI:MGI:5902668|PMID:27328625
Biological Process	GO:2001256	regulation of store-operated calcium entry	SLC8B1	IDA		Human	PMID:28219928
Biological Process	GO:0035725	sodium ion transmembrane transport	Slc8b1	IDA		Mouse	PMID:14625281

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern