Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLC9A6
  • Mouse genes Slc9a6
  • Rat genes Slc9a6
  • Zfish genes slc9a6a,slc9a6b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slc9a6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	SLC9A6	IDA		Human	PMID:32277048
Molecular Function	GO:0015386	potassium:proton antiporter activity	Slc9a6	IDA		Mouse	MGI:MGI:7387161|PMID:17005858
Molecular Function	GO:0005515	protein binding	SLC9A6	IPI	UniProtKB:P63244	Human	PMID:18057008
Molecular Function	GO:0015385	sodium:proton antiporter activity	Slc9a6	IDA		Mouse	MGI:MGI:7387161|PMID:17005858
Cellular Component	GO:0043679	axon terminus	Slc9a6	IDA		Mouse	PMID:23303939
Cellular Component	GO:0044308	axonal spine	Slc9a6	IDA		Mouse	PMID:23303939
Cellular Component	GO:0031410	cytoplasmic vesicle	Slc9a6	IDA		Mouse	PMID:23303939
Cellular Component	GO:0030425	dendrite	Slc9a6	IDA		Mouse	PMID:23303939
Cellular Component	GO:0005769	early endosome	Slc9a6	IDA		Mouse	PMID:24035762
Cellular Component	GO:0031901	early endosome membrane	SLC9A6	IDA		Human	PMID:11940519
Cellular Component	GO:0031901	early endosome membrane	SLC9A6	IDA		Human	PMID:28635961
Cellular Component	GO:0005789	endoplasmic reticulum membrane	SLC9A6	IDA		Human	PMID:11641397
Cellular Component	GO:0005768	endosome	Slc9a6	IDA		Mouse	PMID:24035762
Cellular Component	GO:0098978	glutamatergic synapse	Slc9a6	IDA		Mouse	PMID:31175985
Cellular Component	GO:0098978	glutamatergic synapse	Slc9a6	IMP		Mouse	PMID:31175985
Cellular Component	GO:0098978	glutamatergic synapse	Slc9a6	EXP		Mouse	PMID:31175985
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	SLC9A6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005770	late endosome	Slc9a6	IDA		Mouse	PMID:24035762
Cellular Component	GO:0005739	mitochondrion	Slc9a6	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005886	plasma membrane	SLC9A6	IDA		Human	PMID:11940519
Cellular Component	GO:0005886	plasma membrane	SLC9A6	IDA		Human	PMID:28635961
Cellular Component	GO:0005886	plasma membrane	Slc9a6	IDA		Mouse	MGI:MGI:7387161|PMID:17005858
Cellular Component	GO:0005886	plasma membrane	Slc9a6	IDA		Mouse	PMID:23303939
Cellular Component	GO:0055037	recycling endosome	Slc9a6	IDA		Mouse	PMID:23303939
Cellular Component	GO:0055037	recycling endosome	Slc9a6	IDA		Mouse	PMID:24035762
Cellular Component	GO:0055038	recycling endosome membrane	SLC9A6	IDA		Human	PMID:11940519
Cellular Component	GO:0055038	recycling endosome membrane	SLC9A6	IDA		Human	PMID:18057008
Cellular Component	GO:0055038	recycling endosome membrane	SLC9A6	IDA		Human	PMID:28635961
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Slc9a6	IDA		Mouse	PMID:31175985
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Slc9a6	IMP		Mouse	PMID:31175985
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Slc9a6	EXP		Mouse	PMID:31175985
Cellular Component	GO:0045202	synapse	Slc9a6	IDA		Mouse	PMID:24035762
Biological Process	GO:0048675	axon extension	SLC9A6	IDA		Human	PMID:24035762
Biological Process	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway	Slc9a6	IMP	MGI:MGI:3604561	Mouse	PMID:24035762
Biological Process	GO:0097484	dendrite extension	SLC9A6	IDA		Human	PMID:24035762
Biological Process	GO:0060996	dendritic spine development	Slc9a6	IMP	MGI:MGI:3604561	Mouse	PMID:24035762
Biological Process	GO:0030010	establishment of cell polarity	SLC9A6	IMP		Human	PMID:20130086
Biological Process	GO:0048812	neuron projection morphogenesis	SLC9A6	IDA		Human	PMID:24035762
Biological Process	GO:1902600	proton transmembrane transport	Slc9a6	IMP		Mouse	PMID:24035762
Biological Process	GO:0051453	regulation of intracellular pH	SLC9A6	IDA		Human	PMID:28635961
Biological Process	GO:0051453	regulation of intracellular pH	SLC9A6	IMP		Human	PMID:30296617
Biological Process	GO:0051453	regulation of intracellular pH	Slc9a6	IDA		Mouse	MGI:MGI:7387161|PMID:17005858
Biological Process	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway	Slc9a6	IMP	MGI:MGI:3604561	Mouse	PMID:24035762
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Slc9a6	IDA		Mouse	PMID:31175985
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Slc9a6	EXP		Mouse	PMID:31175985
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Slc9a6	IMP		Mouse	PMID:31175985
Biological Process	GO:0050808	synapse organization	Slc9a6	IMP	MGI:MGI:3604561	Mouse	PMID:24035762

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern