Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SLCO1A2
  • Mouse genes Slco1a4
  • Rat genes Slco1a4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Slco1a4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015125	bile acid transmembrane transporter activity	Slco1a4	IDA		Rat	PMID:9294213|RGD:729806
Molecular Function	GO:0008514	organic anion transmembrane transporter activity	SLCO1A2	IDA		Human	PMID:10873595
Molecular Function	GO:0008514	organic anion transmembrane transporter activity	SLCO1A2	IDA		Human	PMID:19129463
Molecular Function	GO:0008514	organic anion transmembrane transporter activity	Slco1a4	IDA		Mouse	PMID:12101011
Molecular Function	GO:0008514	organic anion transmembrane transporter activity	Slco1a4	IDA		Rat	PMID:19129463|RGD:155230708
Molecular Function	GO:0008514	organic anion transmembrane transporter activity	Slco1a4	IDA		Rat	PMID:9294213|RGD:729806
Molecular Function	GO:0022857	transmembrane transporter activity	SLCO1A2	IDA		Human	PMID:25132355
Cellular Component	GO:0009925	basal plasma membrane	SLCO1A2	IDA		Human	PMID:35307651
Cellular Component	GO:0009925	basal plasma membrane	Slco1a4	IDA		Rat	PMID:18619525|RGD:2301072
Cellular Component	GO:0016020	membrane	Slco1a4	IDA		Mouse	PMID:11279518
Cellular Component	GO:0005886	plasma membrane	SLCO1A2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	SLCO1A2	IDA		Human	PMID:25132355
Biological Process	GO:0015721	bile acid and bile salt transport	Slco1a4	IEP		Rat	PMID:27090119|RGD:15090804
Biological Process	GO:0038183	bile acid signaling pathway	Slco1a4	IEP		Rat	PMID:27090119|RGD:15090804
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Slco1a4	IEP		Rat	PMID:27090119|RGD:15090804
Biological Process	GO:0006820	monoatomic anion transport	Slco1a4	IDA		Mouse	PMID:12101011
Biological Process	GO:0015711	organic anion transport	Slco1a4	IDA		Mouse	MGI:MGI:2182694|PMID:12101011
Biological Process	GO:0120188	regulation of bile acid secretion	Slco1a4	IEP		Rat	PMID:27090119|RGD:15090804
Biological Process	GO:0010468	regulation of gene expression	Slco1a4	IEP		Rat	PMID:27090119|RGD:15090804
Biological Process	GO:0043627	response to estrogen	Slco1a4	IEP		Rat	PMID:27090119|RGD:15090804
Biological Process	GO:0043252	sodium-independent organic anion transport	Slco1a4	IDA		Rat	PMID:9294213|RGD:729806
Biological Process	GO:0055085	transmembrane transport	Slco1a4	IDA		Mouse	MGI:MGI:2182694|PMID:12101011

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern