Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SMAD4
  • Mouse genes Smad4
  • Rat genes Smad4
  • Zfish genes smad4a,smad4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Smad4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Smad4	IDA		Mouse	PMID:15657445
Molecular Function	GO:0003682	chromatin binding	Smad4	IDA		Mouse	PMID:18212064
Molecular Function	GO:0005518	collagen binding	Smad4	IPI	PR:P08121	Mouse	PMID:14559231
Molecular Function	GO:0005518	collagen binding	Smad4	IPI	PR:Q3U962	Mouse	PMID:14559231
Molecular Function	GO:0005518	collagen binding	Smad4	IPI	PR:Q01149	Mouse	PMID:14559231
Molecular Function	GO:0003677	DNA binding	SMAD4	IDA		Human	PMID:9389648
Molecular Function	GO:0003677	DNA binding	Smad4	IDA		Mouse	PMID:15459107
Molecular Function	GO:0003677	DNA binding	Smad4	IDA		Mouse	PMID:12270938
Molecular Function	GO:0003677	DNA binding	Smad4	IDA		Rat	PMID:16959941|RGD:1599906
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	SMAD4	IDA		Human	PMID:18832382
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	SMAD4	IDA		Human	PMID:9389648
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Smad4	IDA		Mouse	MGI:MGI:3851310|PMID:19366691
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Smad4	IGI	UniProtKB:P43694	Mouse	MGI:MGI:4946551|PMID:21330551
Molecular Function	GO:0003700	DNA-binding transcription factor activity	SMAD4	IDA		Human	PMID:10823886
Molecular Function	GO:0003700	DNA-binding transcription factor activity	SMAD4	IDA		Human	PMID:17438144
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Smad4	IDA		Mouse	PMID:12943993
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Smad4	IDA		Mouse	PMID:16556916
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Smad4	IDA		Mouse	PMID:14633973
Molecular Function	GO:0031005	filamin binding	Smad4	IPI	RGD:1560614	Rat	PMID:20167606|RGD:7207405
Molecular Function	GO:0070411	I-SMAD binding	SMAD4	IPI	UniProtKB:O43541	Human	PMID:9256479
Molecular Function	GO:0042802	identical protein binding	SMAD4	IPI	UniProtKB:Q13485	Human	PMID:10647180
Molecular Function	GO:0042802	identical protein binding	SMAD4	IPI	UniProtKB:Q13485	Human	PMID:21988832
Molecular Function	GO:0042802	identical protein binding	SMAD4	IPI	UniProtKB:Q13485	Human	PMID:25609649
Molecular Function	GO:0042802	identical protein binding	SMAD4	IPI	UniProtKB:Q13485	Human	PMID:9111321
Molecular Function	GO:0042802	identical protein binding	Smad4	IPI	PR:P97471	Mouse	PMID:21724602
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q8WUH2	Human	PMID:11278302
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q15797	Human	PMID:11779505
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P12755	Human	PMID:12419246
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P12755	Human	PMID:14525983
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q9UI36	Human	PMID:14525983
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q8N6I1	Human	PMID:14612439
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P56177	Human	PMID:14671321
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:O43524	Human	PMID:15084259
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P98177	Human	PMID:15084259
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P12755	Human	PMID:15231748
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P12757	Human	PMID:15231748
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P63279	Human	PMID:15231748
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:15231748
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q15796	Human	PMID:15231748
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q15797	Human	PMID:15231748
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q9NPI6	Human	PMID:15231748
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:15350224
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q15796	Human	PMID:15350224
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q9UNE7	Human	PMID:15781469
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:O15198	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P63279	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q01844	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q9Y297	Human	PMID:16865698
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q93062	Human	PMID:17099224
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q15797	Human	PMID:17183365
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P12755	Human	PMID:17469184
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P12757-1	Human	PMID:17469184
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q15796	Human	PMID:18511908
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q9GZV5	Human	PMID:18568018
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:18729074
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q15796	Human	PMID:18729074
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P52926	Human	PMID:18832382
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P12755	Human	PMID:19032343
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P70398	Human	PMID:19135894
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:19135894
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q15796	Human	PMID:19135894
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q93008	Human	PMID:19135894
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q9UPN9	Human	PMID:19135894
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P23769	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q15796	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q9UPN9	Human	PMID:20603019
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P08047	Human	PMID:21297662
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:21297662
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q15796	Human	PMID:21297662
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q92988	Human	PMID:21297662
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:O43524	Human	PMID:21532621
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:21532621
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q15796	Human	PMID:21532621
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:21597466
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q9UPN9	Human	PMID:21597466
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P23769	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P63279	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q15796	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q9UBE8	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:22045334
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:22442258
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q15796	Human	PMID:22442258
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P24468	Human	PMID:23201680
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q9UBE8	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q15797	Human	PMID:24412244
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q96BA8	Human	PMID:25310401
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P61968	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q8WWW0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:O15198	Human	PMID:25502805
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P61968	Human	PMID:25502805
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:25502805
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q8WWW0	Human	PMID:25502805
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:O95365	Human	PMID:25514493
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:O15198	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P12755	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P12757	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q15796	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q9NPI6	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:O95373	Human	PMID:26878725
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q8N1F7	Human	PMID:26878725
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q9HAV4	Human	PMID:26878725
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P12755	Human	PMID:26977879
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q9NPI6	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P63279	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q01844	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q15797	Human	PMID:31467278
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q9NPI6	Human	PMID:31467278
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:O15198	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P61968	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P63279	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q01844	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q8WWW0	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:O15198-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P43268-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P61968	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q08117-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q15797	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q15915	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q8NI38	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:P70056	Human	PMID:9389648
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q15796	Human	PMID:9389648
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q15797	Human	PMID:9436979
Molecular Function	GO:0005515	protein binding	SMAD4	IPI	UniProtKB:Q99966	Human	PMID:9707553
Molecular Function	GO:0005515	protein binding	Smad4	IPI	UniProtKB:Q60698	Mouse	MGI:MGI:6098842|PMID:29072299
Molecular Function	GO:0005515	protein binding	Smad4	IPI	UniProtKB:Q8BUN5	Mouse	MGI:MGI:3829534|PMID:18268325
Molecular Function	GO:0005515	protein binding	Smad4	IPI	UniProtKB:Q8BUN5	Mouse	MGI:MGI:5305872|PMID:22045334
Molecular Function	GO:0005515	protein binding	Smad4	IPI	UniProtKB:Q62432|UniProtKB:Q8BUN5	Mouse	MGI:MGI:4939579|PMID:21145499
Molecular Function	GO:0005515	protein binding	Smad4	IPI	UniProtKB:Q8BUN5	Mouse	MGI:MGI:5315322|PMID:22036565
Molecular Function	GO:0005515	protein binding	Smad4	IPI	UniProtKB:Q8R1H0	Mouse	MGI:MGI:5917473|PMID:26113728
Molecular Function	GO:0005515	protein binding	Smad4	IPI	UniProtKB:Q8BUN5	Mouse	MGI:MGI:5508709|PMID:22442258
Molecular Function	GO:0005515	protein binding	Smad4	IPI	PR:P42669	Mouse	PMID:15282343
Molecular Function	GO:0005515	protein binding	Smad4	IPI	PR:Q8BUN5	Mouse	PMID:21724602
Molecular Function	GO:0005515	protein binding	Smad4	IPI	UniProtKB:Q91V53	Mouse	PMID:14633973
Molecular Function	GO:0005515	protein binding	Smad4	IPI	PR:P41778	Mouse	PMID:14764653
Molecular Function	GO:0005515	protein binding	Smad4	IPI	PR:O70477	Mouse	PMID:14764653
Molecular Function	GO:0005515	protein binding	Smad4	IPI	PR:Q8CHP0	Mouse	PMID:16115198
Molecular Function	GO:0005515	protein binding	Smad4	IPI	PR:O35295	Mouse	PMID:15282343
Molecular Function	GO:0005515	protein binding	Smad4	IPI	PR:Q62432	Mouse	PMID:21724602
Molecular Function	GO:0005515	protein binding	Smad4	IPI	PR:Q62261	Mouse	PMID:12543979
Molecular Function	GO:0005515	protein binding	Smad4	IPI	PR:P70340	Mouse	PMID:21724602
Molecular Function	GO:0005515	protein binding	Smad4	IPI	RGD:1310517	Rat	PMID:15153551|RGD:1599409
Molecular Function	GO:0005515	protein binding	Smad4	IPI	RGD:2401	Rat	PMID:16959941|RGD:1599906
Molecular Function	GO:0005515	protein binding	smad4a	IPI	ZFIN:ZDB-GENE-990603-7	Zfish	PMID:20007318
Molecular Function	GO:0005515	protein binding	smad4a	IPI	ZFIN:ZDB-GENE-991119-8	Zfish	PMID:24488494
Molecular Function	GO:0005515	protein binding	smad4a	IPI	ZFIN:ZDB-GENE-990603-9	Zfish	PMID:24488494
Molecular Function	GO:0005515	protein binding	smad4a	IPI	ZFIN:ZDB-GENE-031014-1	Zfish	PMID:24488494
Molecular Function	GO:0005515	protein binding	smad4a	IPI	ZFIN:ZDB-GENE-030603-1,ZFIN:ZDB-GENE-990415-152	Zfish	PMID:24525188
Molecular Function	GO:0042803	protein homodimerization activity	SMAD4	IPI	UniProtKB:Q13485	Human	PMID:8774881
Molecular Function	GO:0070412	R-SMAD binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:8774881
Molecular Function	GO:0070412	R-SMAD binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:9111321
Molecular Function	GO:0070412	R-SMAD binding	SMAD4	IPI	UniProtKB:Q15796	Human	PMID:9111321
Molecular Function	GO:0070412	R-SMAD binding	SMAD4	IPI	UniProtKB:Q15797	Human	PMID:9111321
Molecular Function	GO:0070412	R-SMAD binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:9311995
Molecular Function	GO:0070412	R-SMAD binding	SMAD4	IPI	UniProtKB:Q15796	Human	PMID:9311995
Molecular Function	GO:0070412	R-SMAD binding	SMAD4	IPI	UniProtKB:P84022	Human	PMID:9732876
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SMAD4	IDA		Human	PMID:18832382
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SMAD4	IDA		Human	PMID:31582430
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SMAD4	IDA		Human	PMID:9389648
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Smad4	IDA		Mouse	PMID:14764653
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Smad4	IGI	UniProtKB:P43694	Mouse	MGI:MGI:4946551|PMID:21330551
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Smad4	IDA		Mouse	PMID:21724602
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Smad4	IPI	UniProtKB:P43694	Mouse	MGI:MGI:4946551|PMID:21330551
Molecular Function	GO:0043565	sequence-specific DNA binding	SMAD4	IDA		Human	PMID:10823886
Molecular Function	GO:0043565	sequence-specific DNA binding	smad4a	IPI	ZFIN:ZDB-GENE-000616-6	Zfish	PMID:21159776
Molecular Function	GO:0046332	SMAD binding	Smad4	IPI	RGD:3032	Rat	PMID:16959941|RGD:1599906
Molecular Function	GO:0043199	sulfate binding	SMAD4	IMP		Human	PMID:10647180
Molecular Function	GO:0000976	transcription cis-regulatory region binding	SMAD4	IDA		Human	PMID:17438144
Molecular Function	GO:0000976	transcription cis-regulatory region binding	smad4a	IDA		Zfish	PMID:24525188
Molecular Function	GO:0001223	transcription coactivator binding	SMAD4	IPI	UniProtKB:Q9ULJ6	Human	PMID:16777850
Cellular Component	GO:0032444	activin responsive factor complex	SMAD4	IDA		Human	PMID:9389648
Cellular Component	GO:0005813	centrosome	SMAD4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000785	chromatin	SMAD4	IDA		Human	PMID:21828274
Cellular Component	GO:0005737	cytoplasm	SMAD4	IDA		Human	PMID:12161428
Cellular Component	GO:0005737	cytoplasm	SMAD4	IDA		Human	PMID:9311995
Cellular Component	GO:0005737	cytoplasm	SMAD4	IDA		Human	PMID:9389648
Cellular Component	GO:0005737	cytoplasm	Smad4	IDA		Mouse	MGI:MGI:2683382|PMID:14691138
Cellular Component	GO:0005737	cytoplasm	Smad4	IDA		Rat	PMID:16570350|RGD:1599901
Cellular Component	GO:0005829	cytosol	SMAD4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0071144	heteromeric SMAD protein complex	SMAD4	IPI		Human	PMID:11779505
Cellular Component	GO:0071144	heteromeric SMAD protein complex	SMAD4	IPI		Human	PMID:15350224
Cellular Component	GO:0005654	nucleoplasm	SMAD4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SMAD4	IDA		Human	PMID:12161428
Cellular Component	GO:0005634	nucleus	SMAD4	IDA		Human	PMID:16007207
Cellular Component	GO:0005634	nucleus	SMAD4	IDA		Human	PMID:9311995
Cellular Component	GO:0005634	nucleus	SMAD4	IDA		Human	PMID:9389648
Cellular Component	GO:0005634	nucleus	Smad4	IDA		Mouse	MGI:MGI:2683382|PMID:14691138
Cellular Component	GO:0005634	nucleus	Smad4	IDA		Mouse	PMID:18692037
Cellular Component	GO:0005634	nucleus	Smad4	IDA		Mouse	PMID:19796622
Cellular Component	GO:0005634	nucleus	Smad4	IDA		Rat	PMID:16959941|RGD:1599906
Cellular Component	GO:0005634	nucleus	Smad4	IDA		Rat	PMID:18684975|RGD:2302517
Cellular Component	GO:0005634	nucleus	smad4a	IDA		Zfish	PMID:20007318
Cellular Component	GO:0032991	protein-containing complex	Smad4	IDA		Rat	PMID:16959941|RGD:1599906
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	Smad4	IDA		Mouse	MGI:MGI:3851310|PMID:19366691
Cellular Component	GO:0071141	SMAD protein complex	SMAD4	IMP		Human	PMID:10647180
Cellular Component	GO:0071141	SMAD protein complex	SMAD4	IDA		Human	PMID:18832382
Cellular Component	GO:0071141	SMAD protein complex	smad4a	IPI	ZFIN:ZDB-GENE-030603-1,ZFIN:ZDB-GENE-990415-152	Zfish	PMID:24525188
Cellular Component	GO:0005667	transcription regulator complex	SMAD4	IPI	UniProtKB:P70056	Human	PMID:12374795
Cellular Component	GO:0005667	transcription regulator complex	SMAD4	IPI	UniProtKB:Q8JIT7	Human	PMID:12374795
Cellular Component	GO:0005667	transcription regulator complex	SMAD4	IDA		Human	PMID:17438144
Cellular Component	GO:0005667	transcription regulator complex	Smad4	IPI	UniProtKB:P70056	Mouse	MGI:MGI:3694154|PMID:9288972
Biological Process	GO:0030325	adrenal gland development	Smad4	IEP		Rat	PMID:12844345|RGD:728125
Biological Process	GO:0007568	aging	Smad4	IEP		Rat	PMID:25185054|RGD:12880043
Biological Process	GO:0009952	anterior/posterior pattern specification	Smad4	IMP	MGI:MGI:1857691,MGI:MGI:2656539,MGI:MGI:2668393	Mouse	PMID:15215210
Biological Process	GO:0036302	atrioventricular canal development	Smad4	IGI	UniProtKB:Q08369	Mouse	MGI:MGI:4946551|PMID:21330551
Biological Process	GO:0003190	atrioventricular valve formation	Smad4	IGI	UniProtKB:Q08369	Mouse	MGI:MGI:4946551|PMID:21330551
Biological Process	GO:0007411	axon guidance	Smad4	IMP	MGI:MGI:2386393,MGI:MGI:4459942	Mouse	PMID:21300867
Biological Process	GO:0030509	BMP signaling pathway	SMAD4	IDA		Human	PMID:8637600
Biological Process	GO:0030509	BMP signaling pathway	SMAD4	IDA		Human	PMID:9389648
Biological Process	GO:0030509	BMP signaling pathway	Smad4	IMP		Mouse	MGI:MGI:3769957|PMID:16330325
Biological Process	GO:0003360	brainstem development	Smad4	IMP	MGI:MGI:2386393,MGI:MGI:4459942	Mouse	PMID:21300867
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	Smad4	IGI	MGI:MGI:88177	Mouse	PMID:15925496
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	Smad4	IGI	MGI:MGI:104903	Mouse	PMID:15925496
Biological Process	GO:0048738	cardiac muscle tissue development	smad4a	IMP	ZFIN:ZDB-MRPHLNO-170209-3	Zfish	PMID:27477184
Biological Process	GO:0003279	cardiac septum development	Smad4	IGI	UniProtKB:Q08369	Mouse	MGI:MGI:4946551|PMID:21330551
Biological Process	GO:0008283	cell population proliferation	Smad4	IGI	MGI:MGI:88039	Mouse	PMID:11197776
Biological Process	GO:0008283	cell population proliferation	Smad4	IGI	MGI:MGI:88039	Mouse	PMID:9506519
Biological Process	GO:0008283	cell population proliferation	Smad4	IGI	MGI:MGI:88039	Mouse	PMID:10626800
Biological Process	GO:0008283	cell population proliferation	Smad4	IGI	MGI:MGI:104903	Mouse	PMID:15925496
Biological Process	GO:0008283	cell population proliferation	Smad4	IGI	MGI:MGI:88177	Mouse	PMID:15925496
Biological Process	GO:0008283	cell population proliferation	Smad4	IMP	MGI:MGI:1858049	Mouse	PMID:9420335
Biological Process	GO:0071333	cellular response to glucose stimulus	Smad4	IDA		Rat	PMID:24941801|RGD:12880051
Biological Process	GO:0060026	convergent extension	smad4a	IGI	ZFIN:ZDB-GENE-990603-8	Zfish	PMID:28468752
Biological Process	GO:0060026	convergent extension	smad4a	IMP		Zfish	PMID:28468752
Biological Process	GO:0048264	determination of ventral identity	smad4a	IMP	ZFIN:ZDB-MRPHLNO-140701-1	Zfish	PMID:24525188
Biological Process	GO:0048264	determination of ventral identity	smad4a	IGI	ZFIN:ZDB-MRPHLNO-110607-1,ZFIN:ZDB-MRPHLNO-140701-1,ZFIN:ZDB-MRPHLNO-140701-4	Zfish	PMID:24525188
Biological Process	GO:0048264	determination of ventral identity	smad4a	IGI	ZFIN:ZDB-MRPHLNO-110607-1,ZFIN:ZDB-MRPHLNO-140701-1	Zfish	PMID:24525188
Biological Process	GO:0048589	developmental growth	Smad4	IMP	MGI:MGI:1858049	Mouse	PMID:9420335
Biological Process	GO:0006351	DNA-templated transcription	SMAD4	IDA		Human	PMID:11779505
Biological Process	GO:0042733	embryonic digit morphogenesis	Smad4	IMP		Mouse	MGI:MGI:5444318|PMID:23034633
Biological Process	GO:0060956	endocardial cell differentiation	Smad4	IMP		Mouse	MGI:MGI:4946551|PMID:21330551
Biological Process	GO:0007492	endoderm development	Smad4	IMP	MGI:MGI:1858049	Mouse	PMID:9420335
Biological Process	GO:0042118	endothelial cell activation	Smad4	IMP		Mouse	MGI:MGI:4946551|PMID:21330551
Biological Process	GO:0010631	epithelial cell migration	SMAD4	IMP		Human	PMID:30741461
Biological Process	GO:0001837	epithelial to mesenchymal transition	SMAD4	IMP		Human	PMID:30741461
Biological Process	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	Smad4	IMP		Mouse	MGI:MGI:4946551|PMID:21330551
Biological Process	GO:0070371	ERK1 and ERK2 cascade	Smad4	IMP		Rat	PMID:11401854|RGD:12903275
Biological Process	GO:0008585	female gonad development	Smad4	IGI	MGI:MGI:1349428	Mouse	PMID:24739304
Biological Process	GO:0061040	female gonad morphogenesis	Smad4	IMP	MGI:MGI:2386394	Mouse	PMID:24739304
Biological Process	GO:0048859	formation of anatomical boundary	Smad4	IMP	MGI:MGI:1858049	Mouse	PMID:9420335
Biological Process	GO:0007369	gastrulation	Smad4	IMP	MGI:MGI:1858049	Mouse	PMID:9420335
Biological Process	GO:0001702	gastrulation with mouth forming second	Smad4	IMP	MGI:MGI:1857691,MGI:MGI:2656539,MGI:MGI:2668393	Mouse	PMID:15215210
Biological Process	GO:0001701	in utero embryonic development	Smad4	IMP	MGI:MGI:1858049	Mouse	PMID:9420335
Biological Process	GO:0070102	interleukin-6-mediated signaling pathway	Smad4	IDA		Mouse	MGI:MGI:3769957|PMID:16330325
Biological Process	GO:0006879	intracellular iron ion homeostasis	Smad4	IMP		Mouse	MGI:MGI:3769957|PMID:16330325
Biological Process	GO:0035556	intracellular signal transduction	SMAD4	IMP		Human	PMID:22316667
Biological Process	GO:0001822	kidney development	Smad4	IMP	MGI:MGI:3624262,MGI:MGI:3626290	Mouse	PMID:15342483
Biological Process	GO:0003220	left ventricular cardiac muscle tissue morphogenesis	Smad4	IMP		Mouse	MGI:MGI:3689643|PMID:16151019
Biological Process	GO:0008584	male gonad development	Smad4	IMP	MGI:MGI:2386394	Mouse	PMID:24739304
Biological Process	GO:0007498	mesoderm development	Smad4	IMP	MGI:MGI:1858049	Mouse	PMID:9420335
Biological Process	GO:0072133	metanephric mesenchyme morphogenesis	Smad4	IMP		Mouse	MGI:MGI:3623046|PMID:15342483
Biological Process	GO:0010614	negative regulation of cardiac muscle hypertrophy	Smad4	IMP		Mouse	MGI:MGI:3689643|PMID:16151019
Biological Process	GO:1905305	negative regulation of cardiac myofibril assembly	Smad4	IMP		Mouse	MGI:MGI:3689643|PMID:16151019
Biological Process	GO:0060548	negative regulation of cell death	Smad4	IMP		Mouse	MGI:MGI:3623046|PMID:15342483
Biological Process	GO:0030308	negative regulation of cell growth	SMAD4	IDA		Human	PMID:8774881
Biological Process	GO:0008285	negative regulation of cell population proliferation	Smad4	IGI	MGI:MGI:88039	Mouse	PMID:9506519
Biological Process	GO:0008285	negative regulation of cell population proliferation	Smad4	IGI	MGI:MGI:88039	Mouse	PMID:11197776
Biological Process	GO:0008285	negative regulation of cell population proliferation	Smad4	IGI	MGI:MGI:104903	Mouse	PMID:15925496
Biological Process	GO:0008285	negative regulation of cell population proliferation	Smad4	IGI	MGI:MGI:88177	Mouse	PMID:15925496
Biological Process	GO:0008285	negative regulation of cell population proliferation	Smad4	IGI	MGI:MGI:88039	Mouse	PMID:10626800
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	SMAD4	IDA		Human	PMID:8774881
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Smad4	IMP		Mouse	MGI:MGI:3689643|PMID:16151019
Biological Process	GO:0042177	negative regulation of protein catabolic process	Smad4	IMP		Rat	PMID:20097766|RGD:11079190
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Smad4	IMP		Mouse	MGI:MGI:3807465|PMID:18539898
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Smad4	IMP		Mouse	MGI:MGI:3769957|PMID:16330325
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Smad4	IMP		Mouse	MGI:MGI:3689643|PMID:16151019
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Smad4	IMP	MGI:MGI:2386394	Mouse	PMID:24739304
Biological Process	GO:0072134	nephrogenic mesenchyme morphogenesis	Smad4	IMP		Mouse	MGI:MGI:3623046|PMID:15342483
Biological Process	GO:0014033	neural crest cell differentiation	Smad4	IMP		Mouse	PMID:19793887
Biological Process	GO:0048663	neuron fate commitment	Smad4	IMP	MGI:MGI:2386393,MGI:MGI:2386570	Mouse	PMID:17698011
Biological Process	GO:0001649	osteoblast differentiation	Smad4	IMP		Rat	PMID:19940863|RGD:12880052
Biological Process	GO:0003148	outflow tract septum morphogenesis	Smad4	IGI	UniProtKB:Q63961	Mouse	MGI:MGI:3721185|PMID:17628518
Biological Process	GO:0001541	ovarian follicle development	Smad4	IGI	MGI:MGI:1349428	Mouse	PMID:24739304
Biological Process	GO:0001541	ovarian follicle development	Smad4	IMP	MGI:MGI:2386394	Mouse	PMID:24739304
Biological Process	GO:0001541	ovarian follicle development	Smad4	IEP		Rat	PMID:15698987|RGD:12903277
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	SMAD4	IMP		Human	PMID:19366699
Biological Process	GO:0010666	positive regulation of cardiac muscle cell apoptotic process	Smad4	IMP		Rat	PMID:15949472|RGD:12903280
Biological Process	GO:0003251	positive regulation of cell proliferation involved in heart valve morphogenesis	Smad4	IMP		Mouse	MGI:MGI:4946551|PMID:21330551
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	SMAD4	IDA		Human	PMID:8774881
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	SMAD4	IDA		Human	PMID:9311995
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	SMAD4	IDA		Human	PMID:9389648
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	SMAD4	IDA		Human	PMID:9707553
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	SMAD4	IDA		Human	PMID:9732876
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Smad4	IDA		Mouse	PMID:15282343
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	Smad4	IMP		Mouse	MGI:MGI:2683382|PMID:14691138
Biological Process	GO:0046881	positive regulation of follicle-stimulating hormone secretion	Smad4	IGI	MGI:MGI:1349428	Mouse	PMID:24739304
Biological Process	GO:0046881	positive regulation of follicle-stimulating hormone secretion	Smad4	IMP	MGI:MGI:2386394	Mouse	PMID:24739304
Biological Process	GO:0051571	positive regulation of histone H3-K4 methylation	Smad4	IMP		Mouse	MGI:MGI:3769957|PMID:16330325
Biological Process	GO:2000617	positive regulation of histone H3-K9 acetylation	Smad4	IMP		Mouse	MGI:MGI:3769957|PMID:16330325
Biological Process	GO:0033686	positive regulation of luteinizing hormone secretion	Smad4	IGI	MGI:MGI:1349428	Mouse	PMID:24739304
Biological Process	GO:0033686	positive regulation of luteinizing hormone secretion	Smad4	IMP	MGI:MGI:2386394	Mouse	PMID:24739304
Biological Process	GO:1902895	positive regulation of miRNA transcription	Smad4	IMP		Mouse	MGI:MGI:6094665|PMID:23426367
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	Smad4	IMP		Mouse	MGI:MGI:2683382|PMID:14691138
Biological Process	GO:0060391	positive regulation of SMAD protein signal transduction	Smad4	IMP		Mouse	MGI:MGI:2683382|PMID:14691138
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	SMAD4	IDA		Human	PMID:18832382
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	SMAD4	IDA		Human	PMID:9389648
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad4	IMP		Mouse	MGI:MGI:3769957|PMID:16330325
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad4	IDA		Mouse	MGI:MGI:4946551|PMID:21330551
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad4	IDA		Mouse	MGI:MGI:3851310|PMID:19366691
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad4	IMP		Mouse	MGI:MGI:3807465|PMID:18539898
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad4	IGI	MGI:MGI:1314872	Mouse	PMID:17159989
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad4	IGI	MGI:MGI:98727	Mouse	PMID:17159989
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad4	IGI	MGI:MGI:1201674	Mouse	PMID:17159989
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad4	IDA		Mouse	PMID:16556916
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad4	IGI	MGI:MGI:1349428	Mouse	PMID:24739304
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad4	IMP	MGI:MGI:2386393	Mouse	PMID:18692037
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad4	IDA		Mouse	PMID:9702197
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad4	IGI	MGI:MGI:98725	Mouse	PMID:17568773
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad4	IGI	MGI:MGI:1321394	Mouse	PMID:18986983
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad4	IGI	MGI:MGI:1347465	Mouse	PMID:17568773
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad4	IDA		Mouse	PMID:19251704
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad4	IGI	MGI:MGI:108051	Mouse	PMID:17159989
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smad4	IMP	MGI:MGI:2386394	Mouse	PMID:24739304
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	SMAD4	IDA		Human	PMID:19328798
Biological Process	GO:0051098	regulation of binding	Smad4	IDA		Mouse	PMID:15282343
Biological Process	GO:0042127	regulation of cell population proliferation	Smad4	IGI	MGI:MGI:88039	Mouse	PMID:10708962
Biological Process	GO:0042127	regulation of cell population proliferation	Smad4	IGI	MGI:MGI:88039	Mouse	PMID:11809702
Biological Process	GO:0042127	regulation of cell population proliferation	Smad4	IGI	MGI:MGI:97788	Mouse	PMID:11809702
Biological Process	GO:0042127	regulation of cell population proliferation	Smad4	IMP	MGI:MGI:1857697	Mouse	PMID:10708962
Biological Process	GO:0042127	regulation of cell population proliferation	Smad4	IGI	MGI:MGI:97798	Mouse	PMID:11809702
Biological Process	GO:0051797	regulation of hair follicle development	Smad4	IMP	MGI:MGI:2386393	Mouse	PMID:18692037
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Smad4	IDA		Mouse	PMID:12270938
Biological Process	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	SMAD4	IMP		Human	PMID:8774881
Biological Process	GO:0032909	regulation of transforming growth factor beta2 production	SMAD4	IMP		Human	PMID:12411310
Biological Process	GO:0001666	response to hypoxia	SMAD4	IMP		Human	PMID:12411310
Biological Process	GO:0071559	response to transforming growth factor beta	SMAD4	IDA		Human	PMID:9707553
Biological Process	GO:0048733	sebaceous gland development	Smad4	IMP	MGI:MGI:2386393	Mouse	PMID:18692037
Biological Process	GO:0062009	secondary palate development	Smad4	IMP		Mouse	MGI:MGI:2683382|PMID:14691138
Biological Process	GO:0072520	seminiferous tubule development	Smad4	IMP	MGI:MGI:2386394	Mouse	PMID:24739304
Biological Process	GO:0007338	single fertilization	Smad4	IGI	MGI:MGI:1349428	Mouse	PMID:24739304
Biological Process	GO:0007519	skeletal muscle tissue development	smad4a	IMP	ZFIN:ZDB-MRPHLNO-170209-3	Zfish	PMID:27477184
Biological Process	GO:0007183	SMAD protein complex assembly	SMAD4	IDA		Human	PMID:10823886
Biological Process	GO:0060395	SMAD protein signal transduction	SMAD4	IDA		Human	PMID:9707553
Biological Process	GO:0060395	SMAD protein signal transduction	SMAD4	IDA		Human	PMID:9732876
Biological Process	GO:0032525	somite rostral/caudal axis specification	Smad4	IMP	MGI:MGI:1858049	Mouse	PMID:9420335
Biological Process	GO:0007283	spermatogenesis	Smad4	IMP	MGI:MGI:2386394	Mouse	PMID:24739304
Biological Process	GO:0048729	tissue morphogenesis	Smad4	IMP	MGI:MGI:1858049	Mouse	PMID:9420335
Biological Process	GO:0006366	transcription by RNA polymerase II	Smad4	IMP	MGI:MGI:2386393	Mouse	PMID:18692037
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	SMAD4	IMP		Human	PMID:25514493
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	SMAD4	IDA		Human	PMID:9389648
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	SMAD4	IDA		Human	PMID:9732876
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Smad4	IMP		Mouse	MGI:MGI:3769957|PMID:16330325
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Smad4	IGI	MGI:MGI:98834	Mouse	PMID:18212064
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Smad4	IGI	MGI:MGI:108051	Mouse	PMID:18212064
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Smad4	IGI	MGI:MGI:98725	Mouse	PMID:18212064
Biological Process	GO:0060065	uterus development	Smad4	IGI	MGI:MGI:1349428	Mouse	PMID:24739304
Biological Process	GO:0060412	ventricular septum morphogenesis	Smad4	IMP		Mouse	MGI:MGI:3689643|PMID:16151019
Biological Process	GO:0042060	wound healing	Smad4	IEP		Rat	PMID:15980223|RGD:12903273
Biological Process	GO:0042060	wound healing	Smad4	IMP		Rat	PMID:21255090|RGD:12880045

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern