Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SMAD9
  • Mouse genes Smad9
  • Rat genes Smad9
  • Zfish genes smad9
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Smad9

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SMAD9	IPI	UniProtKB:Q13485	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	SMAD9	IPI	UniProtKB:O60341	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	SMAD9	IPI	UniProtKB:Q96LA8	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	SMAD9	IPI	UniProtKB:Q13485	Human	PMID:25502805
Molecular Function	GO:0005515	protein binding	SMAD9	IPI	UniProtKB:Q13485	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	SMAD9	IPI	UniProtKB:Q86VV4	Human	PMID:25755279
Molecular Function	GO:0005515	protein binding	SMAD9	IPI	UniProtKB:Q13485	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Smad9	IPI	PR:Q04211	Mouse	PMID:15542835
Molecular Function	GO:0005515	protein binding	Smad9	IPI	PR:Q61471	Mouse	PMID:11163184
Molecular Function	GO:0005515	protein binding	Smad9	IPI	RGD:1352527	Rat	PMID:9371779|RGD:70780
Molecular Function	GO:0005515	protein binding	smad9	IPI	ZFIN:ZDB-GENE-990603-8	Zfish	PMID:24488494
Cellular Component	GO:0005737	cytoplasm	Smad9	IDA		Mouse	MGI:MGI:4352622|PMID:19252488
Cellular Component	GO:0005737	cytoplasm	Smad9	IDA		Mouse	PMID:19103752
Cellular Component	GO:0005829	cytosol	SMAD9	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SMAD9	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Smad9	IDA		Mouse	MGI:MGI:4352622|PMID:19252488
Cellular Component	GO:0005634	nucleus	Smad9	IDA		Mouse	PMID:19103752
Cellular Component	GO:0005634	nucleus	Smad9	IDA		Mouse	PMID:19793887
Cellular Component	GO:0005634	nucleus	Smad9	IDA		Mouse	PMID:18776146
Biological Process	GO:0030509	BMP signaling pathway	Smad9	IGI	UniProtKB:P20722	Mouse	MGI:MGI:4352622|PMID:19252488
Biological Process	GO:0030509	BMP signaling pathway	Smad9	IDA		Mouse	PMID:18590716
Biological Process	GO:0030509	BMP signaling pathway	Smad9	IGI	MGI:MGI:1328787	Mouse	PMID:19224984
Biological Process	GO:0030509	BMP signaling pathway	Smad9	IGI	MGI:MGI:109452	Mouse	PMID:19224984
Biological Process	GO:0060348	bone development	Smad9	IGI	MGI:MGI:1328787	Mouse	PMID:19224984
Biological Process	GO:0060348	bone development	Smad9	IGI	MGI:MGI:109452	Mouse	PMID:19224984
Biological Process	GO:0051216	cartilage development	Smad9	IGI	MGI:MGI:109452	Mouse	PMID:19224984
Biological Process	GO:0051216	cartilage development	Smad9	IGI	MGI:MGI:1328787	Mouse	PMID:19224984
Biological Process	GO:0071407	cellular response to organic cyclic compound	Smad9	IDA		Mouse	PMID:19103752
Biological Process	GO:0009953	dorsal/ventral pattern formation	smad9	IGI	ZFIN:ZDB-MRPHLNO-140620-6,ZFIN:ZDB-MRPHLNO-140620-7	Zfish	PMID:24488494
Biological Process	GO:0009953	dorsal/ventral pattern formation	smad9	IGI	ZFIN:ZDB-MRPHLNO-041217-8,ZFIN:ZDB-MRPHLNO-140620-6	Zfish	PMID:24488494
Biological Process	GO:0030902	hindbrain development	Smad9	IMP	MGI:MGI:3581766	Mouse	PMID:15899870
Biological Process	GO:0030901	midbrain development	Smad9	IMP	MGI:MGI:3581766	Mouse	PMID:15899870
Biological Process	GO:0001880	Mullerian duct regression	Smad9	IMP		Rat	PMID:16687449|RGD:2303145
Biological Process	GO:0061515	myeloid cell development	smad9	IMP	ZFIN:ZDB-MRPHLNO-140620-6	Zfish	PMID:24488494
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	smad9	IDA		Zfish	PMID:24488494
Biological Process	GO:0045597	positive regulation of cell differentiation	Smad9	IDA		Rat	PMID:16585960|RGD:2303147
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Smad9	IDA		Rat	PMID:9371779|RGD:70780
Biological Process	GO:0006468	protein phosphorylation	Smad9	IDA		Mouse	PMID:18776146
Biological Process	GO:0001666	response to hypoxia	Smad9	IEP		Rat	PMID:17515860|RGD:2303144
Biological Process	GO:0060395	SMAD protein signal transduction	Smad9	IGI	UniProtKB:P20722	Mouse	MGI:MGI:4352622|PMID:19252488
Biological Process	GO:0001657	ureteric bud development	Smad9	IEP		Mouse	MGI:MGI:3525982|PMID:14656760

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern