Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Smarca5

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SMARCA5
- Mouse genes Smarca5
- Rat genes Smarca5
- Zfish genes smarca5
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Smarca5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	SMARCA5	IDA		Human	PMID:12972596
Molecular Function	GO:0016887	ATP hydrolysis activity	SMARCA5	IDA		Human	PMID:12972596
Molecular Function	GO:0140658	ATP-dependent chromatin remodeler activity	SMARCA5	IMP		Human	PMID:15543136
Molecular Function	GO:0140658	ATP-dependent chromatin remodeler activity	SMARCA5	IDA		Human	PMID:23911928
Molecular Function	GO:0003677	DNA binding	SMARCA5	IDA		Human	PMID:12972596
Molecular Function	GO:0042393	histone binding	SMARCA5	IDA		Human	PMID:12972596
Molecular Function	GO:0140751	histone octamer slider activity	SMARCA5	IDA		Human	PMID:9836642
Molecular Function	GO:0005515	protein binding	SMARCA5	IPI	UniProtKB:Q9NRL2	Human	PMID:10655480
Molecular Function	GO:0005515	protein binding	SMARCA5	IPI	UniProtKB:Q9UIF8	Human	PMID:10662543
Molecular Function	GO:0005515	protein binding	SMARCA5	IPI	UniProtKB:Q9NRL2	Human	PMID:11980720
Molecular Function	GO:0005515	protein binding	SMARCA5	IPI	UniProtKB:Q9UIG0	Human	PMID:11980720
Molecular Function	GO:0005515	protein binding	SMARCA5	IPI	UniProtKB:Q96T23	Human	PMID:12972596
Molecular Function	GO:0005515	protein binding	SMARCA5	IPI	UniProtKB:Q9UIG0	Human	PMID:15543136
Molecular Function	GO:0005515	protein binding	SMARCA5	IPI	UniProtKB:Q9UIG0	Human	PMID:16514417
Molecular Function	GO:0005515	protein binding	SMARCA5	IPI	UniProtKB:P62805	Human	PMID:16917504
Molecular Function	GO:0005515	protein binding	SMARCA5	IPI	UniProtKB:Q8N6T7	Human	PMID:23911928
Molecular Function	GO:0005515	protein binding	SMARCA5	IPI	UniProtKB:Q5T5X7	Human	PMID:26100909
Molecular Function	GO:0005515	protein binding	SMARCA5	IPI	UniProtKB:Q9UIG0	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	Smarca5	IPI	UniProtKB:Q91YE5	Mouse	MGI:MGI:3587127\|PMID:16085498
Molecular Function	GO:0005515	protein binding	Smarca5	IPI	UniProtKB:P54843	Mouse	MGI:MGI:3624889\|PMID:16675956
Molecular Function	GO:0005515	protein binding	Smarca5	IPI	UniProtKB:Q9Z277	Mouse	MGI:MGI:2179578\|PMID:11980720
Molecular Function	GO:0005515	protein binding	Smarca5	IPI	UniProtKB:Q9Z277	Mouse	MGI:MGI:3829305\|PMID:19092802
Cellular Component	GO:0016590	ACF complex	SMARCA5	IPI		Human	PMID:10655480
Cellular Component	GO:0110016	B-WICH complex	SMARCA5	IDA		Human	PMID:16603771
Cellular Component	GO:0005677	chromatin silencing complex	Smarca5	IDA		Mouse	MGI:MGI:3587127\|PMID:16085498
Cellular Component	GO:0000793	condensed chromosome	SMARCA5	IDA		Human	PMID:12972596
Cellular Component	GO:0001650	fibrillar center	SMARCA5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031010	ISWI-type complex	Smarca5	IPI	UniProtKB:E9Q2Z1	Mouse	PMID:22154806
Cellular Component	GO:0090536	NoRC complex	Smarca5	IPI		Mouse	MGI:MGI:2149896\|PMID:11532953
Cellular Component	GO:0043596	nuclear replication fork	SMARCA5	IDA		Human	PMID:15543136
Cellular Component	GO:0005654	nucleoplasm	SMARCA5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SMARCA5	IDA		Human	PMID:10655480
Cellular Component	GO:0005634	nucleus	SMARCA5	IDA		Human	PMID:12972596
Cellular Component	GO:0005634	nucleus	Smarca5	IDA		Mouse	PMID:11980720
Cellular Component	GO:0005634	nucleus	Smarca5	IDA		Mouse	PMID:16880268
Cellular Component	GO:0016589	NURF complex	SMARCA5	IDA		Human	PMID:20850016
Cellular Component	GO:0005721	pericentric heterochromatin	SMARCA5	EXP		Human	PMID:12434153
Cellular Component	GO:0005721	pericentric heterochromatin	Smarca5	IDA		Mouse	MGI:MGI:2179578\|PMID:11980720
Cellular Component	GO:0005721	pericentric heterochromatin	Smarca5	IDA		Mouse	MGI:MGI:6810810\|PMID:12434153
Cellular Component	GO:0031213	RSF complex	SMARCA5	IPI		Human	PMID:12972596
Cellular Component	GO:0031213	RSF complex	SMARCA5	IPI	UniProtKB:Q96T23	Human	PMID:9836642
Cellular Component	GO:0035861	site of double-strand break	SMARCA5	IDA		Human	PMID:23911928
Cellular Component	GO:0090535	WICH complex	SMARCA5	IDA		Human	PMID:16514417
Biological Process	GO:0003231	cardiac ventricle development	smarca5	IMP	ZFIN:ZDB-MRPHLNO-150318-2	Zfish	PMID:25517466
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Smarca5	IEP		Mouse	PMID:20439489
Biological Process	GO:0006325	chromatin organization	Smarca5	IDA		Mouse	PMID:11980720
Biological Process	GO:0006338	chromatin remodeling	SMARCA5	IDA		Human	PMID:10880450
Biological Process	GO:0006338	chromatin remodeling	SMARCA5	IMP		Human	PMID:15543136
Biological Process	GO:0006338	chromatin remodeling	SMARCA5	IDA		Human	PMID:9836642
Biological Process	GO:0006338	chromatin remodeling	Smarca5	IDA		Mouse	PMID:11980720
Biological Process	GO:0006338	chromatin remodeling	Smarca5	IGI	MGI:MGI:2151152	Mouse	PMID:11532953
Biological Process	GO:0006281	DNA repair	SMARCA5	IDA		Human	PMID:23911928
Biological Process	GO:0006352	DNA-templated transcription initiation	SMARCA5	IDA		Human	PMID:9836642
Biological Process	GO:0009790	embryo development	Smarca5	IMP		Mouse	PMID:16880268
Biological Process	GO:0031507	heterochromatin formation	Smarca5	IDA		Mouse	MGI:MGI:3653583\|PMID:16678107
Biological Process	GO:1905213	negative regulation of mitotic chromosome condensation	SMARCA5	IDA		Human	PMID:15543136
Biological Process	GO:1905213	negative regulation of mitotic chromosome condensation	SMARCA5	IMP		Human	PMID:15543136
Biological Process	GO:0016479	negative regulation of transcription by RNA polymerase I	Smarca5	IDA		Mouse	MGI:MGI:2389510\|PMID:12368916
Biological Process	GO:0006334	nucleosome assembly	SMARCA5	EXP		Human	PMID:11691835
Biological Process	GO:0006334	nucleosome assembly	SMARCA5	IDA		Human	PMID:12972596
Biological Process	GO:0006334	nucleosome assembly	SMARCA5	IDA		Human	PMID:14759371
Biological Process	GO:0045740	positive regulation of DNA replication	SMARCA5	IMP		Human	PMID:12434153
Biological Process	GO:0045740	positive regulation of DNA replication	Smarca5	IMP		Mouse	MGI:MGI:6810810\|PMID:12434153
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Smarca5	IMP		Mouse	PMID:16880268
Biological Process	GO:0031065	positive regulation of histone deacetylation	Smarca5	IDA		Mouse	MGI:MGI:3852313\|PMID:12198165
Biological Process	GO:0031062	positive regulation of histone methylation	Smarca5	IDA		Mouse	MGI:MGI:4462332\|PMID:20168299
Biological Process	GO:0045945	positive regulation of transcription by RNA polymerase III	SMARCA5	IDA		Human	PMID:16603771
Biological Process	GO:0000183	rDNA heterochromatin formation	Smarca5	IDA		Mouse	MGI:MGI:3587127\|PMID:16085498
Biological Process	GO:0000183	rDNA heterochromatin formation	Smarca5	IDA		Mouse	MGI:MGI:3852313\|PMID:12198165
Biological Process	GO:0044030	regulation of DNA methylation	Smarca5	IDA		Mouse	MGI:MGI:2389510\|PMID:12368916
Biological Process	GO:0006275	regulation of DNA replication	SMARCA5	IMP		Human	PMID:12434153
Biological Process	GO:0006355	regulation of DNA-templated transcription	SMARCA5	IDA		Human	PMID:12972596
Biological Process	GO:0060041	retina development in camera-type eye	smarca5	IMP	ZFIN:ZDB-GENO-020426-44	Zfish	PMID:15716491

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.