Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SMG1
  • Mouse genes Smg1
  • Rat genes
  • Zfish genes smg1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Smg1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SMG1	IPI	UniProtKB:Q92900	Human	PMID:11544179
Molecular Function	GO:0005515	protein binding	SMG1	IPI	UniProtKB:Q9HAU5	Human	PMID:11544179
Molecular Function	GO:0005515	protein binding	SMG1	IPI	UniProtKB:P11940	Human	PMID:16452507
Molecular Function	GO:0005515	protein binding	SMG1	IPI	UniProtKB:Q9HAU5	Human	PMID:16452507
Molecular Function	GO:0005515	protein binding	SMG1	IPI	UniProtKB:Q9HAU5	Human	PMID:18256688
Molecular Function	GO:0005515	protein binding	SMG1	IPI	UniProtKB:Q8ND04	Human	PMID:19417104
Molecular Function	GO:0005515	protein binding	SMG1	IPI	UniProtKB:Q9H0W8	Human	PMID:19417104
Molecular Function	GO:0005515	protein binding	SMG1	IPI	UniProtKB:Q9HAU5	Human	PMID:19417104
Molecular Function	GO:0005515	protein binding	SMG1	IPI	UniProtKB:Q9HAU5	Human	PMID:20371770
Molecular Function	GO:0005515	protein binding	SMG1	IPI	UniProtKB:Q9Y4R8	Human	PMID:20864032
Molecular Function	GO:0005515	protein binding	SMG1	IPI	UniProtKB:Q14147	Human	PMID:25220460
Molecular Function	GO:0005515	protein binding	SMG1	IPI	UniProtKB:Q14147,UniProtKB:Q8ND04,UniProtKB:Q9H0W8	Human	PMID:26841701
Molecular Function	GO:0005515	protein binding	SMG1	IPI	UniProtKB:Q8ND04,UniProtKB:Q92900,UniProtKB:Q9H0W8	Human	PMID:26841701
Molecular Function	GO:0005515	protein binding	SMG1	IPI	UniProtKB:Q8ND04	Human	PMID:33205750
Molecular Function	GO:0005515	protein binding	SMG1	IPI	UniProtKB:Q9H0W8	Human	PMID:33205750
Molecular Function	GO:0005515	protein binding	SMG1	IPI	UniProtKB:Q9Y230	Human	PMID:33205750
Molecular Function	GO:0005515	protein binding	SMG1	IPI	UniProtKB:Q9Y265	Human	PMID:33205750
Molecular Function	GO:0004697	protein kinase C activity	SMG1	EXP		Human	PMID:11544179
Molecular Function	GO:0004674	protein serine/threonine kinase activity	SMG1	IDA		Human	PMID:11544179
Molecular Function	GO:0004674	protein serine/threonine kinase activity	SMG1	IDA		Human	PMID:15175154
Molecular Function	GO:0004674	protein serine/threonine kinase activity	SMG1	IDA		Human	PMID:19417104
Molecular Function	GO:0003723	RNA binding	SMG1	HDA		Human	PMID:22681889
Molecular Function	GO:0042162	telomeric DNA binding	SMG1	IDA		Human	PMID:17916692
Cellular Component	GO:0033391	chromatoid body	Smg1	IDA		Mouse	MGI:MGI:6453518|PMID:32665638
Cellular Component	GO:0005737	cytoplasm	SMG1	IDA		Human	PMID:14636577
Cellular Component	GO:0005737	cytoplasm	SMG1	IDA		Human	PMID:15175154
Cellular Component	GO:0005654	nucleoplasm	SMG1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SMG1	IDA		Human	PMID:14636577
Cellular Component	GO:0005634	nucleus	SMG1	IDA		Human	PMID:15175154
Biological Process	GO:0006974	DNA damage response	SMG1	IDA		Human	PMID:15175154
Biological Process	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	SMG1	IDA		Human	PMID:11544179
Biological Process	GO:0018105	peptidyl-serine phosphorylation	SMG1	IDA		Human	PMID:11544179
Biological Process	GO:0018105	peptidyl-serine phosphorylation	SMG1	IDA		Human	PMID:15175154
Biological Process	GO:0046854	phosphatidylinositol phosphate biosynthetic process	SMG1	IDA		Human	PMID:11331269
Biological Process	GO:0046777	protein autophosphorylation	SMG1	IDA		Human	PMID:11331269
Biological Process	GO:0046777	protein autophosphorylation	SMG1	IDA		Human	PMID:11544179
Biological Process	GO:0032204	regulation of telomere maintenance	SMG1	IMP		Human	PMID:17916692

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern