Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SMO
  • Mouse genes Smo
  • Rat genes Smo
  • Zfish genes smo
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Smo

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008142	oxysterol binding	smo	IDA		Zfish	PMID:24171105
Molecular Function	GO:0005113	patched binding	SMO	IPI	UniProtKB:Q13635	Human	PMID:9811851
Molecular Function	GO:0005113	patched binding	SMO	IPI	UniProtKB:Q9Y6C5	Human	PMID:9811851
Molecular Function	GO:0005515	protein binding	SMO	IPI	UniProtKB:Q2M1P5	Human	PMID:19592253
Molecular Function	GO:0005515	protein binding	SMO	IPI	UniProtKB:O95995	Human	PMID:21659505
Molecular Function	GO:0005515	protein binding	Smo	IPI	UniProtKB:B7ZNG0|UniProtKB:E9Q9R9|UniProtKB:O08992	Mouse	MGI:MGI:5617062|PMID:25644602
Molecular Function	GO:0005515	protein binding	Smo	IPI	UniProtKB:Q60779	Mouse	MGI:MGI:6148647|PMID:21659505
Molecular Function	GO:0005515	protein binding	Smo	IPI	PR:Q9R0Q3	Mouse	PMID:35353806
Cellular Component	GO:0097731	9+0 non-motile cilium	Smo	IDA		Mouse	PMID:26996322
Cellular Component	GO:0044295	axonal growth cone	Smo	IDA		Rat	PMID:21618238|RGD:5509937
Cellular Component	GO:0005901	caveola	SMO	IDA		Human	PMID:11278759
Cellular Component	GO:0005814	centriole	Smo	IDA		Mouse	PMID:29038301
Cellular Component	GO:0060170	ciliary membrane	Smo	IDA		Mouse	PMID:22179047
Cellular Component	GO:0005929	cilium	SMO	IDA		Human	PMID:27727273
Cellular Component	GO:0005929	cilium	SMO	IDA		Human	PMID:32413283
Cellular Component	GO:0005929	cilium	Smo	IDA		Mouse	MGI:MGI:4888042|PMID:21209331
Cellular Component	GO:0005929	cilium	Smo	IDA		Mouse	MGI:MGI:6148647|PMID:21659505
Cellular Component	GO:0005929	cilium	Smo	IDA		Mouse	MGI:MGI:5617062|PMID:25644602
Cellular Component	GO:0005929	cilium	Smo	IMP		Mouse	PMID:27793670
Cellular Component	GO:0005929	cilium	Smo	IDA		Mouse	PMID:19684112
Cellular Component	GO:0005929	cilium	Smo	IDA		Mouse	PMID:16229832
Cellular Component	GO:0005929	cilium	Smo	IDA		Mouse	PMID:18488998
Cellular Component	GO:0005929	cilium	Smo	IDA		Mouse	PMID:19654211
Cellular Component	GO:0005929	cilium	Smo	IDA		Mouse	PMID:16136078
Cellular Component	GO:0005929	cilium	Smo	IDA		Mouse	PMID:35353806
Cellular Component	GO:0005929	cilium	Smo	IDA		Mouse	PMID:28154160
Cellular Component	GO:0005929	cilium	Smo	IDA		Mouse	PMID:29487109
Cellular Component	GO:0005929	cilium	Smo	IDA		Mouse	PMID:22689656
Cellular Component	GO:0005929	cilium	smo	IDA		Zfish	PMID:27113758
Cellular Component	GO:0005737	cytoplasm	Smo	IDA		Mouse	PMID:18488998
Cellular Component	GO:0005737	cytoplasm	Smo	IDA		Rat	PMID:19484749|RGD:2324985
Cellular Component	GO:0030425	dendrite	Smo	IDA		Rat	PMID:21618238|RGD:5509937
Cellular Component	GO:0044294	dendritic growth cone	Smo	IDA		Rat	PMID:21618238|RGD:5509937
Cellular Component	GO:0005783	endoplasmic reticulum	Smo	IDA		Mouse	PMID:35353806
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	Smo	IDA		Mouse	PMID:35353806
Cellular Component	GO:0070062	extracellular exosome	SMO	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	SMO	HDA		Human	PMID:23533145
Cellular Component	GO:0005794	Golgi apparatus	SMO	IDA		Human	PMID:11278759
Cellular Component	GO:0005794	Golgi apparatus	Smo	IDA		Mouse	PMID:35353806
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	SMO	IDA		Human	PMID:11278759
Cellular Component	GO:0005770	late endosome	Smo	IDA		Mouse	PMID:35353806
Cellular Component	GO:0043025	neuronal cell body	Smo	IDA		Rat	PMID:15356205|RGD:1580344
Cellular Component	GO:0005634	nucleus	Smo	IDA		Rat	PMID:26210874|RGD:12832755
Cellular Component	GO:0005886	plasma membrane	SMO	IDA		Human	PMID:19304771
Cellular Component	GO:0005886	plasma membrane	Smo	IDA		Mouse	MGI:MGI:5306540|PMID:21931618
Cellular Component	GO:0005886	plasma membrane	Smo	IDA		Mouse	PMID:35353806
Cellular Component	GO:0014069	postsynaptic density	Smo	IDA		Rat	PMID:21618238|RGD:5509937
Biological Process	GO:0021984	adenohypophysis development	smo	IMP	ZFIN:ZDB-GENO-990422-74	Zfish	PMID:11566855
Biological Process	GO:0021984	adenohypophysis development	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:11566855
Biological Process	GO:0021984	adenohypophysis development	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:12606279
Biological Process	GO:0071929	alpha-tubulin acetylation	Smo	IMP		Mouse	PMID:27793670
Biological Process	GO:0035479	angioblast cell migration from lateral mesoderm to midline	smo	IMP	ZFIN:ZDB-GENO-011018-2	Zfish	PMID:20193674
Biological Process	GO:0009952	anterior/posterior pattern specification	Smo	IMP	MGI:MGI:2176256,MGI:MGI:2450929	Mouse	PMID:22987639
Biological Process	GO:0009952	anterior/posterior pattern specification	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:12588855
Biological Process	GO:0006915	apoptotic process	Smo	IMP	MGI:MGI:2176256,MGI:MGI:2446434	Mouse	PMID:16571630
Biological Process	GO:0006915	apoptotic process	Smo	IMP		Mouse	PMID:35353806
Biological Process	GO:0060844	arterial endothelial cell fate commitment	smo	IMP	ZFIN:ZDB-GENO-011018-2	Zfish	PMID:20193674
Biological Process	GO:0048143	astrocyte activation	Smo	IMP	MGI:MGI:2176256	Mouse	PMID:23680462
Biological Process	GO:0060413	atrial septum morphogenesis	Smo	IGI	MGI:MGI:102541	Mouse	PMID:22898775
Biological Process	GO:0048846	axon extension involved in axon guidance	Smo	IMP		Rat	PMID:19447091|RGD:2324988
Biological Process	GO:0007411	axon guidance	smo	IMP	ZFIN:ZDB-GENO-070227-2	Zfish	PMID:19846707
Biological Process	GO:0003231	cardiac ventricle development	smo	IMP	ZFIN:ZDB-GENO-070918-2	Zfish	PMID:21558385
Biological Process	GO:0010002	cardioblast differentiation	smo	IMP	ZFIN:ZDB-GENO-090325-3	Zfish	PMID:18842815
Biological Process	GO:0051216	cartilage development	smo	IMP	ZFIN:ZDB-GENO-110830-1	Zfish	PMID:16481351
Biological Process	GO:0035143	caudal fin morphogenesis	smo	IMP	ZFIN:ZDB-GENO-080418-1	Zfish	PMID:17597528
Biological Process	GO:0048468	cell development	Smo	IMP	MGI:MGI:2176256,MGI:MGI:2445832	Mouse	PMID:12403705
Biological Process	GO:0001708	cell fate specification	Smo	IMP	MGI:MGI:2176255	Mouse	PMID:18590716
Biological Process	GO:0008283	cell population proliferation	Smo	IMP		Mouse	PMID:19124651
Biological Process	GO:0008283	cell population proliferation	Smo	IMP	MGI:MGI:2176256,MGI:MGI:2445832	Mouse	PMID:12403705
Biological Process	GO:0071397	cellular response to cholesterol	Smo	IEP		Mouse	MGI:MGI:5306540|PMID:21931618
Biological Process	GO:0007417	central nervous system development	Smo	IGI	MGI:MGI:95729	Mouse	PMID:12435628
Biological Process	GO:0007417	central nervous system development	smo	IMP	ZFIN:ZDB-GENO-101119-5	Zfish	PMID:20806318
Biological Process	GO:0021953	central nervous system neuron differentiation	Smo	IMP	MGI:MGI:2176256,MGI:MGI:2446434	Mouse	PMID:16571630
Biological Process	GO:0021696	cerebellar cortex morphogenesis	Smo	IMP	MGI:MGI:2176173,MGI:MGI:2176256	Mouse	PMID:16571625
Biological Process	GO:0021587	cerebellum morphogenesis	smo	IMP	ZFIN:ZDB-GENO-080605-1	Zfish	PMID:18423594
Biological Process	GO:0021987	cerebral cortex development	Smo	IMP	MGI:MGI:2176256	Mouse	PMID:23680462
Biological Process	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway	smo	IMP	ZFIN:ZDB-GENO-100512-7	Zfish	PMID:19464178
Biological Process	GO:0071679	commissural neuron axon guidance	Smo	IMP		Rat	PMID:19946319|RGD:12879429
Biological Process	GO:0071679	commissural neuron axon guidance	smo	IMP	ZFIN:ZDB-GENO-990422-74	Zfish	PMID:11566855
Biological Process	GO:0071679	commissural neuron axon guidance	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:11566855
Biological Process	GO:0060242	contact inhibition	SMO	IMP		Human	PMID:9422511
Biological Process	GO:0021542	dentate gyrus development	Smo	IMP	MGI:MGI:2176256,MGI:MGI:2179048	Mouse	PMID:18297065
Biological Process	GO:0003140	determination of left/right asymmetry in lateral mesoderm	Smo	IMP		Mouse	MGI:MGI:5142377|PMID:11517919
Biological Process	GO:0007368	determination of left/right symmetry	Smo	IMP	MGI:MGI:2137553	Mouse	PMID:15755804
Biological Process	GO:0007368	determination of left/right symmetry	Smo	IMP	MGI:MGI:2176255	Mouse	PMID:12421714
Biological Process	GO:0048589	developmental growth	Smo	IMP	MGI:MGI:2176256,MGI:MGI:2446434	Mouse	PMID:16571630
Biological Process	GO:0021536	diencephalon development	smo	IGI	ZFIN:ZDB-GENO-080605-1,ZFIN:ZDB-MRPHLNO-070522-3	Zfish	PMID:18358464
Biological Process	GO:0048565	digestive tract development	Smo	IMP	MGI:MGI:2176255	Mouse	PMID:19619492
Biological Process	GO:0071542	dopaminergic neuron differentiation	Smo	IMP	MGI:MGI:2176256,MGI:MGI:2446434	Mouse	PMID:16571630
Biological Process	GO:0035912	dorsal aorta morphogenesis	smo	IMP	ZFIN:ZDB-GENO-011018-2	Zfish	PMID:20193674
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	Smo	IMP	MGI:MGI:2176255	Mouse	PMID:18590716
Biological Process	GO:0009953	dorsal/ventral pattern formation	Smo	IMP	MGI:MGI:2176173,MGI:MGI:2176256	Mouse	PMID:16571630
Biological Process	GO:0009953	dorsal/ventral pattern formation	Smo	IMP	MGI:MGI:2137553	Mouse	PMID:15755804
Biological Process	GO:0031076	embryonic camera-type eye development	smo	IDA		Zfish	PMID:15857917
Biological Process	GO:0048557	embryonic digestive tract morphogenesis	smo	IMP	ZFIN:ZDB-GENO-070918-2	Zfish	PMID:19123126
Biological Process	GO:0048702	embryonic neurocranium morphogenesis	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:16049113
Biological Process	GO:0048568	embryonic organ development	Smo	IGI	MGI:MGI:2144467	Mouse	PMID:24302887
Biological Process	GO:0009880	embryonic pattern specification	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:12889061
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	smo	IMP	ZFIN:ZDB-GENO-110830-1	Zfish	PMID:16481351
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:16580747
Biological Process	GO:0060956	endocardial cell differentiation	smo	IMP	ZFIN:ZDB-MRPHLNO-070719-2	Zfish	PMID:22119054
Biological Process	GO:0031018	endocrine pancreas development	smo	IMP	ZFIN:ZDB-GENO-080507-1	Zfish	PMID:18410733
Biological Process	GO:0031018	endocrine pancreas development	smo	IMP	ZFIN:ZDB-GENO-070918-2	Zfish	PMID:11900460
Biological Process	GO:0035270	endocrine system development	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:15728669
Biological Process	GO:0030855	epithelial cell differentiation	Smo	IMP	MGI:MGI:1934268,MGI:MGI:2445832	Mouse	PMID:17199044
Biological Process	GO:0050673	epithelial cell proliferation	Smo	IMP	MGI:MGI:2176256,MGI:MGI:2445832	Mouse	PMID:12403705
Biological Process	GO:0072175	epithelial tube formation	smo	IMP	ZFIN:ZDB-GENO-100512-7	Zfish	PMID:24504339
Biological Process	GO:0060684	epithelial-mesenchymal cell signaling	Smo	IMP	MGI:MGI:2176256	Mouse	PMID:19304890
Biological Process	GO:0031017	exocrine pancreas development	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:16490192
Biological Process	GO:0021561	facial nerve development	Smo	IEP		Rat	PMID:15356205|RGD:1580344
Biological Process	GO:0021508	floor plate formation	smo	IGI	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:12508225
Biological Process	GO:0030900	forebrain development	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:15533825
Biological Process	GO:0021798	forebrain dorsal/ventral pattern formation	smo	IMP	ZFIN:ZDB-GENO-990422-74	Zfish	PMID:11566855
Biological Process	GO:0021798	forebrain dorsal/ventral pattern formation	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:11566855
Biological Process	GO:0048853	forebrain morphogenesis	Smo	IMP		Mouse	MGI:MGI:5142377|PMID:11517919
Biological Process	GO:0010467	gene expression	Smo	IDA		Mouse	PMID:23201751
Biological Process	GO:0021782	glial cell development	smo	IMP	ZFIN:ZDB-GENO-101119-5	Zfish	PMID:20806318
Biological Process	GO:0021986	habenula development	smo	IMP	ZFIN:ZDB-GENO-081229-14	Zfish	PMID:27387288
Biological Process	GO:0001942	hair follicle development	Smo	IMP	MGI:MGI:1934268,MGI:MGI:2445832	Mouse	PMID:17199044
Biological Process	GO:0031069	hair follicle morphogenesis	Smo	IMP	MGI:MGI:1934268,MGI:MGI:2445832	Mouse	PMID:17199044
Biological Process	GO:0001947	heart looping	Smo	IMP		Mouse	MGI:MGI:5142377|PMID:11517919
Biological Process	GO:0001947	heart looping	smo	IMP	ZFIN:ZDB-GENO-070918-2	Zfish	PMID:21558385
Biological Process	GO:0003007	heart morphogenesis	Smo	IGI	MGI:MGI:101791	Mouse	PMID:16687132
Biological Process	GO:0030902	hindbrain development	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:15281067
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	Smo	IDA		Mouse	PMID:23680462
Biological Process	GO:0001701	in utero embryonic development	Smo	IMP	MGI:MGI:2176255	Mouse	PMID:17881493
Biological Process	GO:0048839	inner ear development	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:12588855
Biological Process	GO:0042472	inner ear morphogenesis	smo	IMP	ZFIN:ZDB-GENO-071114-15	Zfish	PMID:17574823
Biological Process	GO:0070986	left/right axis specification	Smo	IMP	MGI:MGI:2137553	Mouse	PMID:9636176
Biological Process	GO:0060644	mammary gland epithelial cell differentiation	Smo	IMP	MGI:MGI:1934268,MGI:MGI:2445832	Mouse	PMID:17199044
Biological Process	GO:0060231	mesenchymal to epithelial transition	Smo	IMP		Rat	PMID:22994359|RGD:150521663
Biological Process	GO:0072285	mesenchymal to epithelial transition involved in metanephric renal vesicle formation	Smo	IMP		Mouse	MGI:MGI:3611729|PMID:16396903
Biological Process	GO:0007494	midgut development	Smo	IMP		Mouse	MGI:MGI:5142377|PMID:11517919
Biological Process	GO:0035264	multicellular organism growth	Smo	IGI	MGI:MGI:1341070	Mouse	PMID:18590716
Biological Process	GO:0035264	multicellular organism growth	Smo	IMP	MGI:MGI:2176255	Mouse	PMID:18590716
Biological Process	GO:0042693	muscle cell fate commitment	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:16136078
Biological Process	GO:0042693	muscle cell fate commitment	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:15464578
Biological Process	GO:0007517	muscle organ development	smo	IMP	ZFIN:ZDB-GENO-070227-2	Zfish	PMID:17046741
Biological Process	GO:0007517	muscle organ development	smo	IMP	ZFIN:ZDB-GENO-040129-3	Zfish	PMID:15618520
Biological Process	GO:0051451	myoblast migration	Smo	IGI	MGI:MGI:1927138	Mouse	PMID:22987639
Biological Process	GO:0030239	myofibril assembly	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:15572133
Biological Process	GO:0043066	negative regulation of apoptotic process	Smo	IMP	MGI:MGI:2176256,MGI:MGI:2446434	Mouse	PMID:16571630
Biological Process	GO:0043392	negative regulation of DNA binding	Smo	IMP		Mouse	MGI:MGI:3611729|PMID:16396903
Biological Process	GO:0043392	negative regulation of DNA binding	Smo	IGI	MGI:MGI:95729	Mouse	PMID:16396903
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Smo	IMP		Mouse	MGI:MGI:5619427|PMID:24548465
Biological Process	GO:0030857	negative regulation of epithelial cell differentiation	Smo	IMP	MGI:MGI:1934268,MGI:MGI:2445832	Mouse	PMID:17199044
Biological Process	GO:0010629	negative regulation of gene expression	Smo	IMP		Mouse	MGI:MGI:3611729|PMID:16396903
Biological Process	GO:0051799	negative regulation of hair follicle development	Smo	IMP	MGI:MGI:1934268,MGI:MGI:2445832	Mouse	PMID:17199044
Biological Process	GO:2000346	negative regulation of hepatocyte proliferation	Smo	IMP		Rat	PMID:22994359|RGD:150521663
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Smo	IMP		Rat	PMID:20848190|RGD:12879463
Biological Process	GO:1901215	negative regulation of neuron death	Smo	IMP		Rat	PMID:20580927|RGD:10400908
Biological Process	GO:1901215	negative regulation of neuron death	Smo	IDA		Rat	PMID:20600593|RGD:150521662
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Smo	IMP	MGI:MGI:2176256	Mouse	PMID:19304890
Biological Process	GO:0007399	nervous system development	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:13129844
Biological Process	GO:0014033	neural crest cell differentiation	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:16502420
Biological Process	GO:0001755	neural crest cell migration	Smo	IGI	MGI:MGI:101791	Mouse	PMID:16687132
Biological Process	GO:0001839	neural plate morphogenesis	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:16502420
Biological Process	GO:0060896	neural plate pattern specification	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:11566855
Biological Process	GO:0060896	neural plate pattern specification	smo	IMP	ZFIN:ZDB-GENO-990422-74	Zfish	PMID:11566855
Biological Process	GO:0007405	neuroblast proliferation	Smo	IGI	MGI:MGI:88274	Mouse	PMID:16543460
Biological Process	GO:0030182	neuron differentiation	smo	IMP	ZFIN:ZDB-GENO-080605-1	Zfish	PMID:18060804
Biological Process	GO:0048663	neuron fate commitment	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:16502420
Biological Process	GO:0031102	neuron projection regeneration	Smo	IEP		Rat	PMID:15356205|RGD:1580344
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Smo	IMP	MGI:MGI:2176256,MGI:MGI:2445832	Mouse	PMID:12403705
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Smo	IMP	MGI:MGI:1934268,MGI:MGI:2445832	Mouse	PMID:17199044
Biological Process	GO:0014003	oligodendrocyte development	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:12167410
Biological Process	GO:0001503	ossification	Smo	IMP	MGI:MGI:2176256,MGI:MGI:2176264	Mouse	PMID:11748145
Biological Process	GO:0001649	osteoblast differentiation	Smo	IMP	MGI:MGI:2176256	Mouse	PMID:14973297
Biological Process	GO:0001649	osteoblast differentiation	Smo	IEP		Rat	PMID:19649528|RGD:2324984
Biological Process	GO:0033687	osteoblast proliferation	Smo	IEP		Rat	PMID:19649528|RGD:2324984
Biological Process	GO:0032474	otolith morphogenesis	smo	IMP	ZFIN:ZDB-GENO-071114-15	Zfish	PMID:17574823
Biological Process	GO:0031016	pancreas development	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:11553330
Biological Process	GO:0031016	pancreas development	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:16055112
Biological Process	GO:0061113	pancreas morphogenesis	Smo	IMP	MGI:MGI:2176256,MGI:MGI:2684317	Mouse	PMID:20185815
Biological Process	GO:0007389	pattern specification process	Smo	IMP	MGI:MGI:2176256	Mouse	PMID:15107405
Biological Process	GO:0010508	positive regulation of autophagy	Smo	IDA		Rat	PMID:31221056|RGD:150521664
Biological Process	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	Smo	IMP		Mouse	MGI:MGI:3611729|PMID:16396903
Biological Process	GO:0030335	positive regulation of cell migration	SMO	IMP		Human	PMID:21671467
Biological Process	GO:0008284	positive regulation of cell population proliferation	Smo	IMP		Mouse	PMID:19124651
Biological Process	GO:0008284	positive regulation of cell population proliferation	Smo	IDA		Rat	PMID:20600593|RGD:150521662
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Smo	IMP		Mouse	MGI:MGI:5619427|PMID:24548465
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	Smo	IMP	MGI:MGI:2176256,MGI:MGI:2445832	Mouse	PMID:12403705
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	Smo	IMP	MGI:MGI:2176256	Mouse	PMID:19304890
Biological Process	GO:0010628	positive regulation of gene expression	SMO	IMP		Human	PMID:21671467
Biological Process	GO:0010628	positive regulation of gene expression	Smo	IMP		Mouse	MGI:MGI:3611729|PMID:16396903
Biological Process	GO:0010628	positive regulation of gene expression	Smo	IMP	MGI:MGI:2176256	Mouse	PMID:23680462
Biological Process	GO:2000491	positive regulation of hepatic stellate cell activation	Smo	IMP		Rat	PMID:22994359|RGD:150521663
Biological Process	GO:0007228	positive regulation of hh target transcription factor activity	Smo	IMP		Mouse	MGI:MGI:5142377|PMID:11517919
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	Smo	IMP	MGI:MGI:2176256	Mouse	PMID:19304890
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Smo	IMP		Mouse	MGI:MGI:5619427|PMID:24548465
Biological Process	GO:2000179	positive regulation of neural precursor cell proliferation	Smo	IMP		Rat	PMID:23696546|RGD:12832759
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	Smo	IGI	MGI:MGI:88274	Mouse	PMID:16543460
Biological Process	GO:0046622	positive regulation of organ growth	Smo	IMP		Mouse	MGI:MGI:5619427|PMID:24548465
Biological Process	GO:0042307	positive regulation of protein import into nucleus	Smo	IGI	MGI:MGI:98297	Mouse	PMID:17043310
Biological Process	GO:0042307	positive regulation of protein import into nucleus	Smo	IGI	MGI:MGI:95729	Mouse	PMID:17043310
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	Smo	IMP		Mouse	PMID:16459297
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	smo	IMP	ZFIN:ZDB-GENO-110907-3	Zfish	PMID:21659505
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smo	IMP	MGI:MGI:2176256	Mouse	PMID:19304890
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Smo	IMP		Mouse	PMID:15906375
Biological Process	GO:1904754	positive regulation of vascular associated smooth muscle cell migration	Smo	IMP		Rat	PMID:24472833|RGD:12879462
Biological Process	GO:0006606	protein import into nucleus	Smo	IGI	MGI:MGI:98297	Mouse	PMID:17043310
Biological Process	GO:0006606	protein import into nucleus	Smo	IGI	MGI:MGI:95729	Mouse	PMID:17043310
Biological Process	GO:0034504	protein localization to nucleus	Smo	IMP		Mouse	PMID:19952108
Biological Process	GO:0050821	protein stabilization	Smo	IDA		Mouse	PMID:19124651
Biological Process	GO:0010468	regulation of gene expression	Smo	IGI	MGI:MGI:1341070	Mouse	PMID:18590716
Biological Process	GO:2000826	regulation of heart morphogenesis	Smo	IMP		Mouse	MGI:MGI:5142377|PMID:11517919
Biological Process	GO:1904672	regulation of somatic stem cell population maintenance	Smo	IMP	MGI:MGI:1934268,MGI:MGI:2445832	Mouse	PMID:17199044
Biological Process	GO:0010033	response to organic substance	Smo	IEP		Rat	PMID:19429033|RGD:2324989
Biological Process	GO:0009611	response to wounding	Smo	IEP		Rat	PMID:15356205|RGD:1580344
Biological Process	GO:0060041	retina development in camera-type eye	smo	IMP	ZFIN:ZDB-GENO-050209-29	Zfish	PMID:12538521
Biological Process	GO:0031290	retinal ganglion cell axon guidance	smo	IMP	ZFIN:ZDB-GENO-101119-5	Zfish	PMID:20806318
Biological Process	GO:0048752	semicircular canal morphogenesis	smo	IMP	ZFIN:ZDB-GENO-071114-15	Zfish	PMID:17574823
Biological Process	GO:0048741	skeletal muscle fiber development	Smo	IMP	MGI:MGI:2176256,MGI:MGI:3573783	Mouse	PMID:22987639
Biological Process	GO:0048741	skeletal muscle fiber development	smo	IMP	ZFIN:ZDB-GENO-080605-1	Zfish	PMID:21147088
Biological Process	GO:0048745	smooth muscle tissue development	SMO	IEP		Human	PMID:17850284
Biological Process	GO:0048745	smooth muscle tissue development	smo	IMP	ZFIN:ZDB-GENO-070918-2	Zfish	PMID:21558385
Biological Process	GO:0007224	smoothened signaling pathway	SMO	IEP		Human	PMID:17850284
Biological Process	GO:0007224	smoothened signaling pathway	SMO	IMP		Human	PMID:19304771
Biological Process	GO:0007224	smoothened signaling pathway	SMO	IMP		Human	PMID:21177415
Biological Process	GO:0007224	smoothened signaling pathway	SMO	IMP		Human	PMID:32413283
Biological Process	GO:0007224	smoothened signaling pathway	SMO	IMP		Human	PMID:9422511
Biological Process	GO:0007224	smoothened signaling pathway	Smo	IMP		Mouse	MGI:MGI:5142377|PMID:11517919
Biological Process	GO:0007224	smoothened signaling pathway	Smo	IMP		Mouse	MGI:MGI:5285138|PMID:21177415
Biological Process	GO:0007224	smoothened signaling pathway	Smo	IMP		Mouse	PMID:27793670
Biological Process	GO:0007224	smoothened signaling pathway	Smo	IGI	MGI:MGI:98297	Mouse	PMID:17043310
Biological Process	GO:0007224	smoothened signaling pathway	Smo	IMP	MGI:MGI:2176256,MGI:MGI:2684317	Mouse	PMID:20185815
Biological Process	GO:0007224	smoothened signaling pathway	Smo	IMP	MGI:MGI:1934268,MGI:MGI:2445832	Mouse	PMID:17199044
Biological Process	GO:0007224	smoothened signaling pathway	Smo	IMP		Mouse	PMID:16136078
Biological Process	GO:0007224	smoothened signaling pathway	Smo	IGI	MGI:MGI:95729	Mouse	PMID:17043310
Biological Process	GO:0007224	smoothened signaling pathway	Smo	IMP	MGI:MGI:2176256	Mouse	PMID:15107405
Biological Process	GO:0007224	smoothened signaling pathway	Smo	IDA		Mouse	PMID:35353806
Biological Process	GO:0007224	smoothened signaling pathway	Smo	IMP		Mouse	PMID:29487109
Biological Process	GO:0007224	smoothened signaling pathway	smo	IMP	ZFIN:ZDB-GENO-011018-1	Zfish	PMID:11493557
Biological Process	GO:0007224	smoothened signaling pathway	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:11566855
Biological Process	GO:0007224	smoothened signaling pathway	smo	IMP	ZFIN:ZDB-GENO-990422-74	Zfish	PMID:11566855
Biological Process	GO:0007224	smoothened signaling pathway	smo	IMP	ZFIN:ZDB-GENO-011018-2	Zfish	PMID:11493557
Biological Process	GO:0007224	smoothened signaling pathway	smo	IMP	ZFIN:ZDB-MRPHLNO-180212-1	Zfish	PMID:28777795
Biological Process	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	Smo	IMP	MGI:MGI:2176173,MGI:MGI:2176256	Mouse	PMID:16571625
Biological Process	GO:0021910	smoothened signaling pathway involved in ventral spinal cord patterning	Smo	IMP		Mouse	MGI:MGI:4888042|PMID:21209331
Biological Process	GO:0021910	smoothened signaling pathway involved in ventral spinal cord patterning	Smo	IMP	MGI:MGI:2176255	Mouse	PMID:19286674
Biological Process	GO:0021523	somatic motor neuron differentiation	smo	IMP	ZFIN:ZDB-GENO-011018-2	Zfish	PMID:11493557
Biological Process	GO:0021523	somatic motor neuron differentiation	smo	IMP	ZFIN:ZDB-GENO-990422-74	Zfish	PMID:11566855
Biological Process	GO:0021523	somatic motor neuron differentiation	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:11566855
Biological Process	GO:0021523	somatic motor neuron differentiation	smo	IMP	ZFIN:ZDB-GENO-011018-1	Zfish	PMID:11493557
Biological Process	GO:0061053	somite development	Smo	IMP		Mouse	MGI:MGI:5142377|PMID:11517919
Biological Process	GO:0061053	somite development	smo	IMP	ZFIN:ZDB-MRPHLNO-180212-1	Zfish	PMID:28777795
Biological Process	GO:0007283	spermatogenesis	Smo	IEP		Rat	PMID:19484749|RGD:2324985
Biological Process	GO:0021520	spinal cord motor neuron cell fate specification	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:12167410
Biological Process	GO:0021522	spinal cord motor neuron differentiation	smo	IMP	ZFIN:ZDB-GENO-070918-2	Zfish	PMID:23707737
Biological Process	GO:0055002	striated muscle cell development	smo	IMP	ZFIN:ZDB-GENO-000821-1	Zfish	PMID:10769242
Biological Process	GO:0055002	striated muscle cell development	smo	IMP	ZFIN:ZDB-GENO-990422-74	Zfish	PMID:10769242
Biological Process	GO:0048794	swim bladder development	smo	IMP	ZFIN:ZDB-GENO-080605-1	Zfish	PMID:21479192
Biological Process	GO:0048795	swim bladder morphogenesis	smo	IMP	ZFIN:ZDB-GENO-080605-1	Zfish	PMID:19422819
Biological Process	GO:0021537	telencephalon development	smo	IMP	ZFIN:ZDB-GENO-080605-1	Zfish	PMID:11239427
Biological Process	GO:0021794	thalamus development	Smo	IMP	MGI:MGI:2176173,MGI:MGI:3576373	Mouse	PMID:19357274
Biological Process	GO:0003323	type B pancreatic cell development	Smo	IMP	MGI:MGI:2176256,MGI:MGI:2684317	Mouse	PMID:20185815
Biological Process	GO:0001570	vasculogenesis	Smo	IMP	MGI:MGI:2176255	Mouse	PMID:15294868
Biological Process	GO:0001570	vasculogenesis	Smo	IMP	MGI:MGI:2176255	Mouse	PMID:17881493
Biological Process	GO:0001570	vasculogenesis	smo	IMP	ZFIN:ZDB-GENO-080605-1	Zfish	PMID:18377889
Biological Process	GO:0007371	ventral midline determination	Smo	IMP		Mouse	MGI:MGI:5142377|PMID:11517919

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern