Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SMYD1
  • Mouse genes Smyd1
  • Rat genes Smyd1
  • Zfish genes smyd1a,smyd1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Smyd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	smyd1b	IDA		Zfish	PMID:16477022
Molecular Function	GO:0017022	myosin binding	smyd1b	IDA		Zfish	PMID:21852424
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:A7E2Y1	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:P30520	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q9BQ04	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q9BVJ6	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q9H8W3	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:P30520	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:O14503	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q8IX15-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q8NCP5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:P30520	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:O14503	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q8NCP5	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:O14503	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q8NCP5	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:A7E2Y1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:O14503	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:P07196	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:P78424	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q03989	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q3YBR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q6J272	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q70EL1-9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q86TH3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q86UY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q92764	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q96L93-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q99750	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q99932-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q9BSH5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q9BVJ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q9BVN2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q9BYV9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q9H0K4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q9H5F2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q9H5J0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q9H8W3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q9HBE1-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q9NP66	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q9NRI5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q9NVL1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD1	IPI	UniProtKB:Q9Y5W9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Smyd1	IPI	PR:O88895	Mouse	PMID:11923873
Molecular Function	GO:0005515	protein binding	Smyd1	IPI	PR:P70288	Mouse	PMID:11923873
Molecular Function	GO:0005515	protein binding	Smyd1	IPI	PR:O09106	Mouse	PMID:11923873
Molecular Function	GO:0003714	transcription corepressor activity	Smyd1	IDA		Mouse	PMID:11923873
Cellular Component	GO:0005737	cytoplasm	Smyd1	IDA		Mouse	PMID:11923873
Cellular Component	GO:0031430	M band	smyd1a	IDA		Zfish	PMID:29331378
Cellular Component	GO:0031430	M band	smyd1b	IDA		Zfish	PMID:29331378
Cellular Component	GO:0005634	nucleus	Smyd1	IDA		Mouse	PMID:11923873
Biological Process	GO:0071690	cardiac muscle myosin thick filament assembly	smyd1b	IMP	ZFIN:ZDB-GENO-120803-3	Zfish	PMID:21852424
Biological Process	GO:0006338	chromatin remodeling	Smyd1	IPI	PR:O09106	Mouse	PMID:11923873
Biological Process	GO:0060047	heart contraction	smyd1b	IMP	ZFIN:ZDB-GENO-980202-480	Zfish	PMID:9007249
Biological Process	GO:0060047	heart contraction	smyd1b	IMP	ZFIN:ZDB-GENO-980202-1486	Zfish	PMID:9007249
Biological Process	GO:0060047	heart contraction	smyd1b	IMP	ZFIN:ZDB-GENO-070808-3	Zfish	PMID:9007249
Biological Process	GO:0007507	heart development	Smyd1	IMP	MGI:MGI:2179298	Mouse	PMID:11923873
Biological Process	GO:0051568	histone H3-K4 methylation	smyd1b	IDA		Zfish	PMID:16477022
Biological Process	GO:0030239	myofibril assembly	smyd1b	IMP	ZFIN:ZDB-MRPHLNO-060524-9	Zfish	PMID:16477022
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Smyd1	IDA		Mouse	PMID:11923873
Biological Process	GO:0045663	positive regulation of myoblast differentiation	SMYD1	IDA		Human	PMID:19783823
Biological Process	GO:0010831	positive regulation of myotube differentiation	SMYD1	IDA		Human	PMID:19783823
Biological Process	GO:0055018	regulation of cardiac muscle fiber development	smyd1b	IMP	ZFIN:ZDB-GENO-200213-8	Zfish	PMID:33958316
Biological Process	GO:0055018	regulation of cardiac muscle fiber development	smyd1b	IMP	ZFIN:ZDB-GENO-200210-1	Zfish	PMID:33958316
Biological Process	GO:0045214	sarcomere organization	smyd1b	IMP	ZFIN:ZDB-GENO-200210-1	Zfish	PMID:33958316
Biological Process	GO:0045214	sarcomere organization	smyd1b	IMP	ZFIN:ZDB-GENO-200213-8	Zfish	PMID:33958316
Biological Process	GO:0045214	sarcomere organization	smyd1a	IMP	ZFIN:ZDB-MRPHLNO-180626-3	Zfish	PMID:29331378
Biological Process	GO:0045214	sarcomere organization	smyd1a	IGI	ZFIN:ZDB-MRPHLNO-060524-9,ZFIN:ZDB-MRPHLNO-140103-2	Zfish	PMID:24466251
Biological Process	GO:0045214	sarcomere organization	smyd1b	IGI	ZFIN:ZDB-MRPHLNO-060524-9,ZFIN:ZDB-MRPHLNO-140103-2	Zfish	PMID:24466251
Biological Process	GO:0045214	sarcomere organization	smyd1b	IMP	ZFIN:ZDB-GENO-120803-3	Zfish	PMID:27295336
Biological Process	GO:0045214	sarcomere organization	smyd1b	IMP	ZFIN:ZDB-MRPHLNO-060524-9	Zfish	PMID:24466251
Biological Process	GO:0048769	sarcomerogenesis	smyd1b	IMP	ZFIN:ZDB-GENO-120803-3	Zfish	PMID:21852424
Biological Process	GO:0048769	sarcomerogenesis	smyd1b	IMP	ZFIN:ZDB-GENO-980202-1486	Zfish	PMID:26544721
Biological Process	GO:0035914	skeletal muscle cell differentiation	Smyd1	IMP		Mouse	PMID:22147266
Biological Process	GO:0048741	skeletal muscle fiber development	smyd1b	IMP	ZFIN:ZDB-GENO-200213-8	Zfish	PMID:33958316
Biological Process	GO:0048741	skeletal muscle fiber development	smyd1b	IMP	ZFIN:ZDB-GENO-200210-1	Zfish	PMID:33958316
Biological Process	GO:0048741	skeletal muscle fiber development	smyd1a	IMP	ZFIN:ZDB-GENO-200213-6	Zfish	PMID:30817176
Biological Process	GO:0048741	skeletal muscle fiber development	smyd1b	IMP	ZFIN:ZDB-GENO-200210-1	Zfish	PMID:30817176
Biological Process	GO:0048741	skeletal muscle fiber development	smyd1b	IMP	ZFIN:ZDB-GENO-200213-6	Zfish	PMID:30817176
Biological Process	GO:0030241	skeletal muscle myosin thick filament assembly	smyd1a	IGI	ZFIN:ZDB-MRPHLNO-060524-9,ZFIN:ZDB-MRPHLNO-140103-2	Zfish	PMID:24466251
Biological Process	GO:0030241	skeletal muscle myosin thick filament assembly	smyd1b	IMP	ZFIN:ZDB-GENO-120803-3	Zfish	PMID:21852424
Biological Process	GO:0030241	skeletal muscle myosin thick filament assembly	smyd1b	IGI	ZFIN:ZDB-MRPHLNO-060524-9,ZFIN:ZDB-MRPHLNO-140103-2	Zfish	PMID:24466251
Biological Process	GO:0030241	skeletal muscle myosin thick filament assembly	smyd1b	IMP	ZFIN:ZDB-MRPHLNO-060524-9	Zfish	PMID:24466251
Biological Process	GO:0030240	skeletal muscle thin filament assembly	smyd1a	IGI	ZFIN:ZDB-MRPHLNO-060524-9,ZFIN:ZDB-MRPHLNO-140103-2	Zfish	PMID:24466251
Biological Process	GO:0030240	skeletal muscle thin filament assembly	smyd1b	IGI	ZFIN:ZDB-MRPHLNO-060524-9,ZFIN:ZDB-MRPHLNO-140103-2	Zfish	PMID:24466251
Biological Process	GO:0030240	skeletal muscle thin filament assembly	smyd1b	IMP	ZFIN:ZDB-MRPHLNO-060524-9	Zfish	PMID:24466251
Biological Process	GO:0014866	skeletal myofibril assembly	smyd1a	IMP	ZFIN:ZDB-MRPHLNO-180626-3	Zfish	PMID:29331378
Biological Process	GO:0014866	skeletal myofibril assembly	smyd1a	IMP	ZFIN:ZDB-CRISPR-180627-1	Zfish	PMID:29331378
Biological Process	GO:0014866	skeletal myofibril assembly	smyd1b	IMP	ZFIN:ZDB-MRPHLNO-060524-9	Zfish	PMID:24068325
Biological Process	GO:0014866	skeletal myofibril assembly	smyd1b	IMP	ZFIN:ZDB-GENO-070813-2,ZFIN:ZDB-MRPHLNO-060524-10	Zfish	PMID:24068325
Biological Process	GO:0055002	striated muscle cell development	smyd1b	IMP	ZFIN:ZDB-GENO-980202-1486	Zfish	PMID:31644553
Biological Process	GO:0001966	thigmotaxis	smyd1a	IMP	ZFIN:ZDB-MRPHLNO-180626-2	Zfish	PMID:29331378
Biological Process	GO:0001966	thigmotaxis	smyd1a	IMP	ZFIN:ZDB-CRISPR-180627-1	Zfish	PMID:29331378
Biological Process	GO:0001966	thigmotaxis	smyd1a	IMP	ZFIN:ZDB-MRPHLNO-180626-3	Zfish	PMID:29331378

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern