Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SMYD5
  • Mouse genes Smyd5
  • Rat genes Smyd5
  • Zfish genes smyd5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Smyd5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042799	histone H4K20 methyltransferase activity	Smyd5	IMP		Mouse	MGI:MGI:6709288|PMID:28250819
Molecular Function	GO:0042799	histone H4K20 methyltransferase activity	Smyd5	IMP		Mouse	MGI:MGI:6716956|PMID:22921934
Molecular Function	GO:0005515	protein binding	SMYD5	IPI	UniProtKB:Q8TAU3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SMYD5	IPI	UniProtKB:Q96SQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Smyd5	IPI	UniProtKB:Q61686|UniProtKB:Q9Z148	Mouse	MGI:MGI:6709288|PMID:28250819
Biological Process	GO:0060216	definitive hemopoiesis	smyd5	IMP	ZFIN:ZDB-MRPHLNO-160921-1	Zfish	PMID:27377701
Biological Process	GO:0060216	definitive hemopoiesis	smyd5	IMP	ZFIN:ZDB-MRPHLNO-160921-2	Zfish	PMID:27377701
Biological Process	GO:0045814	negative regulation of gene expression, epigenetic	Smyd5	IMP		Mouse	MGI:MGI:6716956|PMID:22921934
Biological Process	GO:0045638	negative regulation of myeloid cell differentiation	smyd5	IMP	ZFIN:ZDB-MRPHLNO-160921-1	Zfish	PMID:27377701
Biological Process	GO:0045638	negative regulation of myeloid cell differentiation	smyd5	IMP	ZFIN:ZDB-MRPHLNO-160921-2	Zfish	PMID:27377701
Biological Process	GO:0010529	negative regulation of transposition	SMYD5	IMP		Human	PMID:28951459
Biological Process	GO:0010529	negative regulation of transposition	Smyd5	IMP		Mouse	MGI:MGI:6103640|PMID:28951459
Biological Process	GO:0060215	primitive hemopoiesis	smyd5	IMP	ZFIN:ZDB-MRPHLNO-160921-1	Zfish	PMID:27377701
Biological Process	GO:0060215	primitive hemopoiesis	smyd5	IMP	ZFIN:ZDB-MRPHLNO-160921-2	Zfish	PMID:27377701
Biological Process	GO:2000736	regulation of stem cell differentiation	SMYD5	IMP		Human	PMID:28951459
Biological Process	GO:2000736	regulation of stem cell differentiation	Smyd5	IMP		Mouse	MGI:MGI:6103640|PMID:28951459
Biological Process	GO:2000736	regulation of stem cell differentiation	Smyd5	IMP		Mouse	MGI:MGI:6709288|PMID:28250819
Biological Process	GO:2000035	regulation of stem cell division	Smyd5	IMP		Mouse	MGI:MGI:6709288|PMID:28250819

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern