Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SNAI2
  • Mouse genes Snai2
  • Rat genes Snai2
  • Zfish genes snai2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Snai2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Snai2	IDA		Mouse	PMID:17905753
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Snai2	IDA		Mouse	PMID:18223155
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	SNAI2	IDA		Human	PMID:10866665
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	SNAI2	IDA		Human	PMID:11912130
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	SNAI2	IDA		Human	PMID:15737616
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	SNAI2	IDA		Human	PMID:16707493
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	SNAI2	IDA		Human	PMID:18663143
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Snai2	IGI	MGI:MGI:98834	Mouse	PMID:16286009
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Snai2	IDA		Mouse	PMID:18663143
Molecular Function	GO:0070888	E-box binding	SNAI2	IDA		Human	PMID:11912130
Molecular Function	GO:0070888	E-box binding	SNAI2	IDA		Human	PMID:15737616
Molecular Function	GO:0070888	E-box binding	SNAI2	IDA		Human	PMID:16707493
Molecular Function	GO:0005515	protein binding	SNAI2	IPI	UniProtKB:P21673	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SNAI2	IPI	UniProtKB:P36406	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SNAI2	IPI	UniProtKB:P36508	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNAI2	IPI	UniProtKB:P68400	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNAI2	IPI	UniProtKB:Q9NPB3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Snai2	IPI	UniProtKB:Q7TQJ8|UniProtKB:Q91XC0|UniProtKB:Q9QXD8	Mouse	MGI:MGI:5318024|PMID:18331720
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	SNAI2	IDA		Human	PMID:11912130
Molecular Function	GO:0043565	sequence-specific DNA binding	SNAI2	IDA		Human	PMID:10518215
Molecular Function	GO:0043565	sequence-specific DNA binding	SNAI2	IDA		Human	PMID:10866665
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	SNAI2	IDA		Human	PMID:28473536
Cellular Component	GO:0000785	chromatin	SNAI2	IDA		Human	PMID:16707493
Cellular Component	GO:0000785	chromatin	SNAI2	IDA		Human	PMID:19756381
Cellular Component	GO:0005737	cytoplasm	Snai2	IDA		Mouse	PMID:20046880
Cellular Component	GO:0005634	nucleus	SNAI2	IDA		Human	PMID:10866665
Cellular Component	GO:0005634	nucleus	SNAI2	IDA		Human	PMID:25893292
Cellular Component	GO:0005634	nucleus	Snai2	IDA		Mouse	PMID:17507657
Cellular Component	GO:0005634	nucleus	Snai2	IDA		Mouse	PMID:20046880
Cellular Component	GO:0005634	nucleus	Snai2	IDA		Mouse	PMID:12833143
Biological Process	GO:0060536	cartilage morphogenesis	Snai2	IGI	MGI:MGI:98330	Mouse	PMID:17376812
Biological Process	GO:0003273	cell migration involved in endocardial cushion formation	Snai2	IMP		Mouse	MGI:MGI:3808643|PMID:18663143
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	SNAI2	IDA		Human	PMID:18716062
Biological Process	GO:0044344	cellular response to fibroblast growth factor stimulus	Snai2	IEP		Rat	PMID:9182671|RGD:730035
Biological Process	GO:0071479	cellular response to ionizing radiation	Snai2	IGI	MGI:MGI:98834	Mouse	PMID:16286009
Biological Process	GO:0071479	cellular response to ionizing radiation	Snai2	IGI	MGI:MGI:2181667	Mouse	PMID:16286009
Biological Process	GO:0006325	chromatin organization	Snai2	IMP		Mouse	PMID:17905753
Biological Process	GO:0035921	desmosome disassembly	SNAI2	IMP		Human	PMID:9182671
Biological Process	GO:0035921	desmosome disassembly	Snai2	IMP		Mouse	MGI:MGI:892810|PMID:9182671
Biological Process	GO:0043542	endothelial cell migration	Snai2	IMP	MGI:MGI:2447175	Mouse	PMID:18663143
Biological Process	GO:0010631	epithelial cell migration	Snai2	IGI	MGI:MGI:98330	Mouse	PMID:17376812
Biological Process	GO:0001837	epithelial to mesenchymal transition	SNAI2	IMP		Human	PMID:17984306
Biological Process	GO:0001837	epithelial to mesenchymal transition	SNAI2	IMP		Human	PMID:9182671
Biological Process	GO:0001837	epithelial to mesenchymal transition	Snai2	IMP		Mouse	MGI:MGI:892810|PMID:9182671
Biological Process	GO:0001837	epithelial to mesenchymal transition	Snai2	IMP	MGI:MGI:2447175	Mouse	PMID:17916597
Biological Process	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	Snai2	IMP	MGI:MGI:2447175	Mouse	PMID:18663143
Biological Process	GO:0060429	epithelium development	Snai2	IMP		Mouse	MGI:MGI:5284759|PMID:18716062
Biological Process	GO:0071425	hematopoietic stem cell proliferation	Snai2	IMP	MGI:MGI:2447174	Mouse	PMID:20032500
Biological Process	GO:0033028	myeloid cell apoptotic process	Snai2	IGI	MGI:MGI:88138	Mouse	PMID:16286009
Biological Process	GO:0033028	myeloid cell apoptotic process	Snai2	IGI	MGI:MGI:98834	Mouse	PMID:16286009
Biological Process	GO:2000811	negative regulation of anoikis	SNAI2	IMP		Human	PMID:17984306
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	SNAI2	IDA		Human	PMID:19502595
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	SNAI2	IMP		Human	PMID:19756381
Biological Process	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration	Snai2	IMP	MGI:MGI:2447175	Mouse	PMID:18663143
Biological Process	GO:0033629	negative regulation of cell adhesion mediated by integrin	SNAI2	IDA		Human	PMID:16707493
Biological Process	GO:0032331	negative regulation of chondrocyte differentiation	SNAI2	IMP		Human	PMID:19756381
Biological Process	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	SNAI2	IMP		Human	PMID:15314165
Biological Process	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	Snai2	IDA		Mouse	PMID:10518215
Biological Process	GO:1902034	negative regulation of hematopoietic stem cell proliferation	Snai2	IMP	MGI:MGI:2447174	Mouse	PMID:20032500
Biological Process	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	SNAI2	IMP		Human	PMID:15314165
Biological Process	GO:0010839	negative regulation of keratinocyte proliferation	SNAI2	IDA		Human	PMID:16707493
Biological Process	GO:0033033	negative regulation of myeloid cell apoptotic process	Snai2	IGI	MGI:MGI:88138	Mouse	PMID:16286009
Biological Process	GO:0033033	negative regulation of myeloid cell apoptotic process	Snai2	IGI	MGI:MGI:98834	Mouse	PMID:16286009
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SNAI2	IDA		Human	PMID:10866665
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SNAI2	IDA		Human	PMID:11912130
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SNAI2	IDA		Human	PMID:15737616
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SNAI2	IDA		Human	PMID:16707493
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SNAI2	IMP		Human	PMID:17984306
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SNAI2	IMP		Human	PMID:18663143
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Snai2	IDA		Mouse	PMID:18223155
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Snai2	IMP		Rat	PMID:16153441|RGD:1600044
Biological Process	GO:0010957	negative regulation of vitamin D biosynthetic process	SNAI2	IDA		Human	PMID:18485278
Biological Process	GO:0010957	negative regulation of vitamin D biosynthetic process	SNAI2	IDA		Human	PMID:19502595
Biological Process	GO:0070563	negative regulation of vitamin D receptor signaling pathway	SNAI2	IDA		Human	PMID:19502595
Biological Process	GO:0014032	neural crest cell development	SNAI2	IMP		Human	PMID:12444107
Biological Process	GO:0007219	Notch signaling pathway	SNAI2	IMP		Human	PMID:18663143
Biological Process	GO:0001649	osteoblast differentiation	SNAI2	IEP		Human	PMID:20128911
Biological Process	GO:0043473	pigmentation	SNAI2	IMP		Human	PMID:12444107
Biological Process	GO:0043473	pigmentation	Snai2	IMP		Mouse	MGI:MGI:2446014|PMID:12444107
Biological Process	GO:0030335	positive regulation of cell migration	SNAI2	IMP		Human	PMID:15314165
Biological Process	GO:0045600	positive regulation of fat cell differentiation	Snai2	IMP	MGI:MGI:2447176	Mouse	PMID:17905753
Biological Process	GO:0045600	positive regulation of fat cell differentiation	Snai2	IGI	MGI:MGI:97747	Mouse	PMID:17905753
Biological Process	GO:2000810	regulation of bicellular tight junction assembly	SNAI2	IMP		Human	PMID:15314165
Biological Process	GO:0060693	regulation of branching involved in salivary gland morphogenesis	Snai2	IMP		Mouse	PMID:20671187
Biological Process	GO:0032642	regulation of chemokine production	SNAI2	IMP		Human	PMID:21182836
Biological Process	GO:0045667	regulation of osteoblast differentiation	SNAI2	IMP		Human	PMID:19756381
Biological Process	GO:0045667	regulation of osteoblast differentiation	SNAI2	IMP		Human	PMID:21182836
Biological Process	GO:0009314	response to radiation	Snai2	IDA		Mouse	PMID:12833143
Biological Process	GO:0009314	response to radiation	Snai2	IMP	MGI:MGI:2447176	Mouse	PMID:12833143
Biological Process	GO:0060021	roof of mouth development	Snai2	IGI	MGI:MGI:98330	Mouse	PMID:17376812
Biological Process	GO:0060021	roof of mouth development	Snai2	IMP	MGI:MGI:2447176	Mouse	PMID:17376812
Biological Process	GO:0007605	sensory perception of sound	SNAI2	IMP		Human	PMID:12444107
Biological Process	GO:0007605	sensory perception of sound	Snai2	IMP		Mouse	MGI:MGI:2446014|PMID:12444107
Biological Process	GO:0006929	substrate-dependent cell migration	Snai2	IMP	MGI:MGI:2447175	Mouse	PMID:18663143
Biological Process	GO:0050872	white fat cell differentiation	Snai2	IGI	MGI:MGI:97747	Mouse	PMID:17905753
Biological Process	GO:0050872	white fat cell differentiation	Snai2	IMP	MGI:MGI:2447176	Mouse	PMID:17905753

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern