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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Snap25

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Snap25
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0048306calcium-dependent protein bindingSnap25IPIUniProtKB:P21707RatPMID:12526776|RGD:10047386
Molecular FunctionGO:0008289lipid bindingSNAP25EXPHumanPMID:30916996
Molecular FunctionGO:0060090molecular adaptor activitySNAP25EXPHumanPMID:30916996
Molecular FunctionGO:0017022myosin bindingSnap25IPIRGD:3143RatPMID:16030255|RGD:1581734
Molecular FunctionGO:0005515protein bindingSNAP25IPIUniProtKB:Q86UR5HumanPMID:11438518
Molecular FunctionGO:0005515protein bindingSNAP25IPIUniProtKB:Q8IUH5HumanPMID:15603740
Molecular FunctionGO:0005515protein bindingSNAP25IPIUniProtKB:Q16623HumanPMID:16169070
Molecular FunctionGO:0005515protein bindingSNAP25IPIUniProtKB:Q16623HumanPMID:26635000
Molecular FunctionGO:0005515protein bindingSNAP25IPIUniProtKB:Q16623HumanPMID:30610939
Molecular FunctionGO:0005515protein bindingSNAP25IPIUniProtKB:O00555HumanPMID:8692999
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:Q155P7MouseMGI:MGI:3814962|PMID:18827011
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:O35526|UniProtKB:P63044MouseMGI:MGI:3703199|PMID:17283335
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:Q80TN5MouseMGI:MGI:5640908|PMID:25253725
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:O35526|UniProtKB:P63044MouseMGI:MGI:4431150|PMID:20114047
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P32851|UniProtKB:P63044MouseMGI:MGI:5919808|PMID:16565726
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P32851|UniProtKB:P63044MouseMGI:MGI:5508581|PMID:19703397
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P32851|UniProtKB:P63044MouseMGI:MGI:6092627|PMID:19805029
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:Q9Z266MouseMGI:MGI:5553043|PMID:23949442
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:Q9CWU2MouseMGI:MGI:5640908|PMID:25253725
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:Q155P7MouseMGI:MGI:3663229|PMID:16672379
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P63044MouseMGI:MGI:4830915|PMID:20798282
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:E9PUL5MouseMGI:MGI:5792766|PMID:27052163
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:Q9ESF1MouseMGI:MGI:3692845|PMID:17055430
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:E9PUL5MouseMGI:MGI:6114881|PMID:29056747
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:O35526|UniProtKB:P63044MouseMGI:MGI:5618598|PMID:24705552
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P63044MouseMGI:MGI:5314486|PMID:22187053
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:Q9R0C0|UniProtKB:Q9UL45MouseMGI:MGI:5442504|PMID:19546860
Molecular FunctionGO:0005515protein bindingSnap25IPIPR:O35526MousePMID:21040848
Molecular FunctionGO:0005515protein bindingSnap25IPIPR:Q64704-2MousePMID:24680688
Molecular FunctionGO:0005515protein bindingSnap25IPIPR:Q9DB05MousePMID:21040848
Molecular FunctionGO:0005515protein bindingSnap25IPIPR:P42859MousePMID:17500595
Molecular FunctionGO:0005515protein bindingSnap25IPIPR:P63044MousePMID:21040848
Molecular FunctionGO:0005515protein bindingSnap25IPIPR:P28663MousePMID:21040848
Molecular FunctionGO:0005515protein bindingSnap25IPIPR:Q9D9V2MousePMID:19285662
Molecular FunctionGO:0005515protein bindingSnap25IPIRGD:2935RatPMID:10373452|RGD:69862
Molecular FunctionGO:0005515protein bindingSnap25IPIRGD:708439RatPMID:10625663|RGD:1299445
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:Q9QXY2RatPMID:10625663|RGD:1299445
Molecular FunctionGO:0005515protein bindingSnap25IPIRGD:69225RatPMID:10825299|RGD:632855
Molecular FunctionGO:0005515protein bindingSnap25IPIRGD:731818RatPMID:11438518|RGD:68912
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P54921RatPMID:11931741|RGD:633462
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P85969RatPMID:11931741|RGD:633462
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:G3V7P1RatPMID:12070131|RGD:9850097
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P32851RatPMID:12496247|RGD:8554115
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P32851RatPMID:15316007|RGD:8554158
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:Q9ES66RatPMID:15471947|RGD:8553339
Molecular FunctionGO:0005515protein bindingSnap25IPIRGD:733780RatPMID:16203731|RGD:1581076
Molecular FunctionGO:0005515protein bindingSnap25IPIRGD:2954RatPMID:16478442|RGD:1581072
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:Q08849RatPMID:16598260|RGD:8553500
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P47709RatPMID:16763567|RGD:8553578
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P32851RatPMID:17717530|RGD:8554124
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P32851RatPMID:18275821|RGD:13432279
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P32851RatPMID:18337752|RGD:8553871
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P32851RatPMID:18822290|RGD:8553696
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P63044RatPMID:19196426|RGD:13702278
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P32851RatPMID:19571812|RGD:13432305
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P63045RatPMID:19571812|RGD:13432305
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P21707RatPMID:20173763|RGD:13432278
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P32851RatPMID:20489724|RGD:8553846
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P32851,UniProtKB:P50232RatPMID:20688915|RGD:11535104
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P32851RatPMID:21193638|RGD:13432275
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P32851RatPMID:22307055|RGD:13432342
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P32851RatPMID:25581794|RGD:13432311
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P63045RatPMID:25814585|RGD:13432338
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:Q80TN5RatPMID:26198635|RGD:11344937
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:Q9CWU2RatPMID:26198635|RGD:11344937
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P32851RatPMID:26389740|RGD:13432323
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P32851RatPMID:26876096|RGD:11573385
Molecular FunctionGO:0005515protein bindingSnap25IPIUniProtKB:P32851RatPMID:9759724|RGD:8553514
Molecular FunctionGO:0019904protein domain specific bindingSnap25IPIRGD:621540RatPMID:11152476|RGD:633988
Molecular FunctionGO:0005484SNAP receptor activitySnap25IDAMousePMID:12145198
Molecular FunctionGO:0000149SNARE bindingSnap25IDAMousePMID:12145198
Molecular FunctionGO:0000149SNARE bindingSnap25IDARatPMID:12177041|RGD:730202
Molecular FunctionGO:0000149SNARE bindingSnap25IPIUniProtKB:P32851,UniProtKB:P63045RatPMID:12680753|RGD:12793015
Molecular FunctionGO:0000149SNARE bindingSnap25IDARatPMID:7553862|RGD:70701
Molecular FunctionGO:0000149SNARE bindingSnap25IPIRGD:61880RatPMID:7698987|RGD:4892592
Molecular FunctionGO:0000149SNARE bindingSnap25IPIUniProtKB:P32851RatPMID:9671503|RGD:12793053
Molecular FunctionGO:0000149SNARE bindingSnap25IPIUniProtKB:P32851,UniProtKB:P63045RatPMID:9671503|RGD:12793053
Molecular FunctionGO:0017075syntaxin-1 bindingSNAP25IPIUniProtKB:Q16623HumanPMID:12730201
Molecular FunctionGO:0017075syntaxin-1 bindingSnap25IDAMouseMGI:MGI:3803800|PMID:18703708
Molecular FunctionGO:0017075syntaxin-1 bindingSnap25IDARatPMID:12177041|RGD:730202
Molecular FunctionGO:0017075syntaxin-1 bindingSnap25IPIRGD:69430RatPMID:16030255|RGD:1581734
Molecular FunctionGO:0017075syntaxin-1 bindingSnap25IDARatPMID:7553862|RGD:70701
Molecular FunctionGO:0044325transmembrane transporter bindingSnap25IPIUniProtKB:P15387RatPMID:19077057|RGD:10047372
Molecular FunctionGO:0005249voltage-gated potassium channel activitySnap25IDARatPMID:16478442|RGD:1581072
Cellular ComponentGO:0015629actin cytoskeletonSnap25IDARatPMID:10625663|RGD:1299445
Cellular ComponentGO:0030424axonSnap25IDAMouseMGI:MGI:5819336|PMID:23821748
Cellular ComponentGO:0030424axonSnap25IDAMouseMGI:MGI:5795818|PMID:21576241
Cellular ComponentGO:0030424axonSnap25IDARatPMID:10712642|RGD:8553882
Cellular ComponentGO:0044295axonal growth coneSnap25IDARatPMID:10712642|RGD:8553882
Cellular ComponentGO:0005938cell cortexSnap25IDAMouseMGI:MGI:5819336|PMID:23821748
Cellular ComponentGO:0005737cytoplasmSNAP25IDAHumanPMID:24327345
Cellular ComponentGO:0005737cytoplasmSnap25IDAMouseMGI:MGI:5442504|PMID:19546860
Cellular ComponentGO:0005737cytoplasmSnap25IDARatPMID:10800949|RGD:1581063
Cellular ComponentGO:0005856cytoskeletonSNAP25IDAHumanPMID:24327345
Cellular ComponentGO:0005829cytosolSnap25IDARatPMID:10340764|RGD:4892571
Cellular ComponentGO:0005768endosomeSnap25IDARatPMID:16481393|RGD:1581071
Cellular ComponentGO:0098888extrinsic component of presynaptic membraneSnap25IDARatPMID:15983999|RGD:155230812
Cellular ComponentGO:0030175filopodiumSnap25IDARatPMID:10625663|RGD:1299445
Cellular ComponentGO:0098978glutamatergic synapseSnap25IDAMousePMID:17728451
Cellular ComponentGO:0098978glutamatergic synapseSnap25IMPMousePMID:17728451
Cellular ComponentGO:0098978glutamatergic synapseSnap25EXPRatPMID:8103915|RGD:13702457
Cellular ComponentGO:0098978glutamatergic synapseSnap25IDARatPMID:8103915|RGD:13702457
Cellular ComponentGO:0030426growth coneSnap25IDARatPMID:16598260|RGD:8553500
Cellular ComponentGO:0043229intracellular organelleSnap25IDARatPMID:10340764|RGD:4892571
Cellular ComponentGO:0030027lamellipodiumSnap25IDARatPMID:10625663|RGD:1299445
Cellular ComponentGO:0016020membraneSnap25IDAMouseMGI:MGI:5442504|PMID:19546860
Cellular ComponentGO:0045121membrane raftSnap25IDARatPMID:15769746|RGD:1581078
Cellular ComponentGO:0043209myelin sheathSnap25HDAMouseMGI:MGI:3834050|PMID:17634366
Cellular ComponentGO:0043005neuron projectionSnap25IDAMousePMID:14622145
Cellular ComponentGO:0043005neuron projectionSnap25IDARatPMID:10625663|RGD:1299445
Cellular ComponentGO:0043005neuron projectionSnap25IDARatPMID:16598260|RGD:8553500
Cellular ComponentGO:0043005neuron projectionSnap25IDARatPMID:21986494|RGD:8553247
Cellular ComponentGO:0043025neuronal cell bodySnap25IDARatPMID:10625663|RGD:1299445
Cellular ComponentGO:0048471perinuclear region of cytoplasmSnap25IDAMouseMGI:MGI:3814962|PMID:18827011
Cellular ComponentGO:0005886plasma membraneSnap25IDARatPMID:21986494|RGD:8553247
Cellular ComponentGO:0005886plasma membranesnap25aIDAZfishPMID:16876784
Cellular ComponentGO:0098794postsynapseSnap25IDAMouseMGI:MGI:4411959|PMID:19679075
Cellular ComponentGO:0098793presynapseSnap25IMPMouseMGI:MGI:5924862|PMID:28404788
Cellular ComponentGO:0048787presynaptic active zone membraneSnap25IDARatPMID:11068331|RGD:12050117
Cellular ComponentGO:0042734presynaptic membraneSnap25IDAMousePMID:24680688
Cellular ComponentGO:0042734presynaptic membraneSnap25IDARatPMID:7698978|RGD:729999
Cellular ComponentGO:0097470ribbon synapseSnap25IDAMousePMID:24680688
Cellular ComponentGO:0031201SNARE complexSNAP25IDAHumanPMID:12130530
Cellular ComponentGO:0031201SNARE complexSNAP25IDAHumanPMID:12730201
Cellular ComponentGO:0031201SNARE complexSnap25IDARatPMID:16030255|RGD:1581734
Cellular ComponentGO:0031201SNARE complexSnap25IDARatPMID:16598260|RGD:8553500
Cellular ComponentGO:0031201SNARE complexSnap25IDARatPMID:23949442|RGD:8553762
Cellular ComponentGO:0036477somatodendritic compartmentSnap25IDAMouseMGI:MGI:5795818|PMID:21576241
Cellular ComponentGO:0045202synapseSnap25IMPMouseMGI:MGI:5924862|PMID:28404788
Cellular ComponentGO:0045202synapseSnap25IDAMousePMID:10712642
Cellular ComponentGO:0008021synaptic vesicleSnap25IDAMousePMID:24680688
Cellular ComponentGO:0070044synaptobrevin 2-SNAP-25-syntaxin-1a complexSnap25IDARatPMID:22711810|RGD:7205652
Cellular ComponentGO:0070044synaptobrevin 2-SNAP-25-syntaxin-1a complexSnap25IMPRatPMID:12680753|RGD:12793015
Cellular ComponentGO:0070044synaptobrevin 2-SNAP-25-syntaxin-1a complexSnap25IDARatPMID:7553862|RGD:70701
Cellular ComponentGO:0070044synaptobrevin 2-SNAP-25-syntaxin-1a complexSnap25IMPRatPMID:9671503|RGD:12793053
Cellular ComponentGO:0070032synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complexSnap25IDAMousePMID:21040848
Cellular ComponentGO:0070032synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complexSnap25IDARatPMID:7553862|RGD:70701
Cellular ComponentGO:0070033synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complexSnap25IDARatPMID:19132534|RGD:7205655
Cellular ComponentGO:0043195terminal boutonSnap25HDARatPMID:24876496|RGD:10047219
Cellular ComponentGO:0005802trans-Golgi networkSnap25IDAMouseMGI:MGI:3814962|PMID:18827011
Cellular ComponentGO:0031982vesicleSNAP25IDAHumanPMID:15459722
Cellular ComponentGO:0008076voltage-gated potassium channel complexSnap25IDARatPMID:16478442|RGD:1581072
Biological ProcessGO:0008306associative learningSnap25IMPMGI:MGI:2180178MousePMID:23064108
Biological ProcessGO:0007409axonogenesisSnap25IEPRatPMID:15478103|RGD:1581079
Biological ProcessGO:0048791calcium ion-regulated exocytosis of neurotransmitterSnap25IDARatPMID:14980208|RGD:1581082
Biological ProcessGO:0045162clustering of voltage-gated sodium channelssnap25bIMPZFIN:ZDB-MRPHLNO-140224-4ZfishPMID:27902705
Biological ProcessGO:0016197endosomal transportSnap25IDARatPMID:16481393|RGD:1581071
Biological ProcessGO:0098967exocytic insertion of neurotransmitter receptor to postsynaptic membraneSnap25IMPMouseMGI:MGI:5494785|PMID:23395379
Biological ProcessGO:0030252growth hormone secretionSnap25IEPRatPMID:14506689|RGD:1581083
Biological ProcessGO:0051179localizationSNAP25EXPHumanPMID:30916996
Biological ProcessGO:0007626locomotory behaviorSnap25IMPMGI:MGI:2180178MousePMID:23064108
Biological ProcessGO:0007626locomotory behaviorsnap25bIMPZFIN:ZDB-GENO-161208-29ZfishPMID:27605615
Biological ProcessGO:0007626locomotory behaviorsnap25aIMPZFIN:ZDB-GENO-161208-28ZfishPMID:27605615
Biological ProcessGO:0007616long-term memorySnap25IMPRatPMID:16870134|RGD:1581067
Biological ProcessGO:0060291long-term synaptic potentiationSnap25IMPMousePMID:23395379
Biological ProcessGO:0000281mitotic cytokinesissnap25aIMPZfishPMID:16876784
Biological ProcessGO:0030182neuron differentiationSnap25IEPRatPMID:24841827|RGD:11570515
Biological ProcessGO:0099590neurotransmitter receptor internalizationSnap25IMPMouseMGI:MGI:4411959|PMID:19679075
Biological ProcessGO:0007269neurotransmitter secretionSnap25IMPMGI:MGI:2180178MousePMID:11753414
Biological ProcessGO:0046887positive regulation of hormone secretionSnap25IMPRatPMID:15147232|RGD:1581080
Biological ProcessGO:0032024positive regulation of insulin secretionSnap25IEPRatPMID:15042624|RGD:1581081
Biological ProcessGO:0099525presynaptic dense core vesicle exocytosisSnap25IDAMousePMID:28404788
Biological ProcessGO:0099525presynaptic dense core vesicle exocytosisSnap25IMPMousePMID:28404788
Biological ProcessGO:0070201regulation of establishment of protein localizationSnap25IMPMousePMID:23395379
Biological ProcessGO:0010975regulation of neuron projection developmentSnap25IGIUniProtKB:Q03343MouseMGI:MGI:5298138|PMID:21986494
Biological ProcessGO:0010975regulation of neuron projection developmentSnap25IMPRatPMID:21986494|RGD:8553247
Biological ProcessGO:0051963regulation of synapse assemblySnap25IEPRatPMID:15478103|RGD:1581079
Biological ProcessGO:0030431sleepSnap25IDARatPMID:16273548|RGD:1581074
Biological ProcessGO:0035493SNARE complex assemblySnap25IMPRatPMID:12680753|RGD:12793015
Biological ProcessGO:0035493SNARE complex assemblySnap25IMPRatPMID:9671503|RGD:12793053
Biological ProcessGO:0016079synaptic vesicle exocytosisSnap25IMPMousePMID:17728451
Biological ProcessGO:0016079synaptic vesicle exocytosisSnap25IDAMousePMID:17728451
Biological ProcessGO:0016079synaptic vesicle exocytosisSnap25EXPRatPMID:8103915|RGD:13702457
Biological ProcessGO:0016079synaptic vesicle exocytosisSnap25IDARatPMID:8103915|RGD:13702457
Biological ProcessGO:0016079synaptic vesicle exocytosisSnap25IEPRatPMID:8103915|RGD:13702457

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory