Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SNCB
  • Mouse genes Sncb
  • Rat genes Sncb
  • Zfish genes sncb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sncb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043014	alpha-tubulin binding	Sncb	IDA		Rat	PMID:18800064|RGD:6218960
Molecular Function	GO:0048487	beta-tubulin binding	Sncb	IDA		Rat	PMID:18800064|RGD:6218960
Molecular Function	GO:0005509	calcium ion binding	SNCB	IDA		Human	PMID:11312271
Molecular Function	GO:1903136	cuprous ion binding	SNCB	IMP		Human	PMID:25495902
Molecular Function	GO:0005515	protein binding	SNCB	IPI	UniProtKB:Q8NDC4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNCB	IPI	UniProtKB:O75925	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SNCB	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SNCB	IPI	UniProtKB:P37840	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SNCB	IPI	UniProtKB:Q8N488	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SNCB	IPI	UniProtKB:Q8NDC4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SNCB	IPI	UniProtKB:Q9GZS3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SNCB	IPI	UniProtKB:Q9UNS2	Human	PMID:32814053
Molecular Function	GO:0046914	transition metal ion binding	SNCB	IMP		Human	PMID:25495902
Cellular Component	GO:0043679	axon terminus	Sncb	IDA		Rat	PMID:12127102|RGD:2291797
Cellular Component	GO:0030426	growth cone	Sncb	IDA		Rat	PMID:12821390|RGD:1358136
Cellular Component	GO:0016234	inclusion body	SNCB	IDA		Human	PMID:17222866
Cellular Component	GO:0005739	mitochondrion	Sncb	HDA		Mouse	PMID:14651853
Cellular Component	GO:0043025	neuronal cell body	Sncb	IDA		Rat	PMID:11716559|RGD:6480189
Cellular Component	GO:0098793	presynapse	Sncb	IMP		Mouse	MGI:MGI:5605098|PMID:25009269
Cellular Component	GO:0099523	presynaptic cytosol	Sncb	IDA		Rat	PMID:7877458|RGD:13702277
Cellular Component	GO:0045202	synapse	Sncb	IMP		Mouse	MGI:MGI:5605098|PMID:25009269
Cellular Component	GO:0045202	synapse	Sncb	IDA		Mouse	PMID:10964942
Cellular Component	GO:0043195	terminal bouton	Sncb	IDA		Rat	PMID:10777786|RGD:737667
Cellular Component	GO:0043195	terminal bouton	Sncb	HDA		Rat	PMID:24876496|RGD:10047219
Biological Process	GO:0007268	chemical synaptic transmission	Sncb	IGI	MGI:MGI:1298397	Mouse	PMID:20974939
Biological Process	GO:0007268	chemical synaptic transmission	Sncb	IGI	MGI:MGI:1277151	Mouse	PMID:20974939
Biological Process	GO:0042417	dopamine metabolic process	Sncb	IGI	MGI:MGI:1277151	Mouse	PMID:15465911
Biological Process	GO:0071542	dopaminergic neuron differentiation	sncb	IGI	ZFIN:ZDB-MRPHLNO-120216-10,ZFIN:ZDB-MRPHLNO-120216-7,ZFIN:ZDB-MRPHLNO-120216-8,ZFIN:ZDB-MRPHLNO-120216-9	Zfish	PMID:22128150
Biological Process	GO:0008345	larval locomotory behavior	sncb	IMP	ZFIN:ZDB-MRPHLNO-120216-7,ZFIN:ZDB-MRPHLNO-120216-8	Zfish	PMID:22128150
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Sncb	IGI	MGI:MGI:892995	Mouse	PMID:16269331
Biological Process	GO:0051402	neuron apoptotic process	Sncb	IGI	MGI:MGI:892995	Mouse	PMID:16269331
Biological Process	GO:0050808	synapse organization	Sncb	IGI	MGI:MGI:1277151	Mouse	PMID:20974939
Biological Process	GO:0050808	synapse organization	Sncb	IGI	MGI:MGI:1298397	Mouse	PMID:20974939
Biological Process	GO:0048488	synaptic vesicle endocytosis	Sncb	IMP		Mouse	PMID:25009269
Biological Process	GO:0048488	synaptic vesicle endocytosis	Sncb	IDA		Mouse	PMID:25009269

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern