Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SNCG
  • Mouse genes Sncg
  • Rat genes Sncg
  • Zfish genes sncga,sncgb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sncg

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043014	alpha-tubulin binding	Sncg	IDA		Rat	PMID:18800064|RGD:6218960
Molecular Function	GO:0048487	beta-tubulin binding	Sncg	IDA		Rat	PMID:18800064|RGD:6218960
Molecular Function	GO:0005515	protein binding	SNCG	IPI	UniProtKB:P54274	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	Sncg	IPI	UniProtKB:O70624	Mouse	MGI:MGI:5554368|PMID:16392033
Molecular Function	GO:0005515	protein binding	Sncg	IPI	RGD:621822	Rat	PMID:18800064|RGD:6218960
Cellular Component	GO:0030424	axon	Sncg	IDA		Mouse	PMID:9801372
Cellular Component	GO:0030424	axon	Sncg	IDA		Mouse	PMID:15147505
Cellular Component	GO:0030424	axon	Sncg	IDA		Mouse	PMID:10195122
Cellular Component	GO:0030424	axon	Sncg	IDA		Mouse	PMID:14585981
Cellular Component	GO:0043679	axon terminus	Sncg	IDA		Rat	PMID:12127102|RGD:2291797
Cellular Component	GO:0005813	centrosome	SNCG	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	SNCG	IDA		Human	PMID:17222866
Cellular Component	GO:0005737	cytoplasm	Sncg	IDA		Mouse	PMID:9801372
Cellular Component	GO:0005737	cytoplasm	Sncg	IDA		Mouse	PMID:15147505
Cellular Component	GO:0005737	cytoplasm	Sncg	IDA		Mouse	PMID:14585981
Cellular Component	GO:0070062	extracellular exosome	SNCG	HDA		Human	PMID:19056867
Cellular Component	GO:0043025	neuronal cell body	Sncg	IDA		Mouse	PMID:9801372
Cellular Component	GO:0043025	neuronal cell body	Sncg	IDA		Mouse	PMID:15147505
Cellular Component	GO:0043025	neuronal cell body	Sncg	IDA		Mouse	PMID:10195122
Cellular Component	GO:0043025	neuronal cell body	Sncg	IDA		Mouse	PMID:14585981
Cellular Component	GO:0043025	neuronal cell body	Sncg	IDA		Rat	PMID:11716559|RGD:6480189
Cellular Component	GO:0043025	neuronal cell body	Sncg	IDA		Rat	PMID:12127102|RGD:2291797
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Sncg	IDA		Rat	PMID:18728752|RGD:6218971
Cellular Component	GO:0005886	plasma membrane	Sncg	IDA		Rat	PMID:18800064|RGD:6218960
Biological Process	GO:0008344	adult locomotory behavior	Sncg	IGI	MGI:MGI:1277151	Mouse	PMID:18333965
Biological Process	GO:0002118	aggressive behavior	Sncg	IEP		Rat	PMID:15660669|RGD:6218975
Biological Process	GO:0071464	cellular response to hydrostatic pressure	Sncg	IEP		Rat	PMID:11933054|RGD:6480100
Biological Process	GO:0007268	chemical synaptic transmission	Sncg	IGI	MGI:MGI:1889011	Mouse	PMID:20974939
Biological Process	GO:0007268	chemical synaptic transmission	Sncg	IGI	MGI:MGI:1277151	Mouse	PMID:20974939
Biological Process	GO:0071542	dopaminergic neuron differentiation	sncgb	IGI	ZFIN:ZDB-MRPHLNO-120216-10,ZFIN:ZDB-MRPHLNO-120216-7,ZFIN:ZDB-MRPHLNO-120216-8,ZFIN:ZDB-MRPHLNO-120216-9	Zfish	PMID:22128150
Biological Process	GO:0008345	larval locomotory behavior	sncgb	IMP	ZFIN:ZDB-MRPHLNO-120216-10,ZFIN:ZDB-MRPHLNO-120216-9	Zfish	PMID:22128150
Biological Process	GO:1901215	negative regulation of neuron death	Sncg	IMP		Rat	PMID:18936092|RGD:13782255
Biological Process	GO:0009306	protein secretion	Sncg	IDA		Mouse	MGI:MGI:5554368|PMID:16392033
Biological Process	GO:0014059	regulation of dopamine secretion	Sncg	IGI	MGI:MGI:1277151	Mouse	PMID:18333965
Biological Process	GO:0046928	regulation of neurotransmitter secretion	Sncg	IGI	MGI:MGI:1277151	Mouse	PMID:18333965
Biological Process	GO:0042220	response to cocaine	Sncg	IEP		Rat	PMID:14622225|RGD:6218992
Biological Process	GO:1904307	response to desipramine	Sncg	IEP		Rat	PMID:19818834|RGD:13506724
Biological Process	GO:0009410	response to xenobiotic stimulus	Sncg	IEP		Rat	PMID:18800064|RGD:6218960
Biological Process	GO:0050808	synapse organization	Sncg	IGI	MGI:MGI:1889011	Mouse	PMID:20974939
Biological Process	GO:0050808	synapse organization	Sncg	IGI	MGI:MGI:1277151	Mouse	PMID:20974939

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern