Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SNX1
  • Mouse genes Snx1
  • Rat genes Snx1
  • Zfish genes snx1a,snx1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Snx1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	SNX1	HDA		Human	PMID:25468996
Molecular Function	GO:0005154	epidermal growth factor receptor binding	SNX1	IDA		Human	PMID:9819414
Molecular Function	GO:0042802	identical protein binding	SNX1	IPI	UniProtKB:Q13596	Human	PMID:11102511
Molecular Function	GO:0042802	identical protein binding	SNX1	IPI	UniProtKB:Q13596	Human	PMID:23085988
Molecular Function	GO:0005158	insulin receptor binding	SNX1	IDA		Human	PMID:9819414
Molecular Function	GO:1990460	leptin receptor binding	SNX1	IDA		Human	PMID:9819414
Molecular Function	GO:0035091	phosphatidylinositol binding	SNX1	IDA		Human	PMID:15498486
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:O60749	Human	PMID:11102511
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q96QK1	Human	PMID:11102511
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:P36897	Human	PMID:11278302
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q13705	Human	PMID:11279102
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q9UNH7	Human	PMID:11279102
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q9UNH7	Human	PMID:19619496
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q9Y5X3	Human	PMID:19619496
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q9UNH7	Human	PMID:19935774
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q12768	Human	PMID:20923837
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q15041	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q86XE0	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q96HR9	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q9UNH7	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q96QK1	Human	PMID:22719997
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q9Y5X3	Human	PMID:23085988
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q9UNH7	Human	PMID:23524952
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:O95197	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q15041	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q6RW13	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q86XE0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q8IVP5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q96DZ9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q96HR9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q9NQC3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q9UI14	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:O60749	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q86XE0	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q9UNH7	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q9Y5X3	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:B3EWG5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:O43759-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:O60664	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:O95563	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:P07510-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:P08247	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:P53701	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q00765	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q5T9G4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q6ZWK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q86XE0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q8IZR5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q8N3Y7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q8WV19	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q8WW34-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q96DZ9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q96HR9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q9H400	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q9NZJ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q9UNH7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q9Y371	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:Q9Y680	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX1	IPI	UniProtKB:O60749	Human	PMID:9819414
Molecular Function	GO:0005515	protein binding	Snx1	IPI	UniProtKB:Q5DTT2	Mouse	MGI:MGI:5562465|PMID:24261326
Molecular Function	GO:0005515	protein binding	Snx1	IPI	PR:Q922H7	Mouse	PMID:15239668
Molecular Function	GO:0005515	protein binding	Snx1	IPI	RGD:69225	Rat	PMID:11110793|RGD:68866
Molecular Function	GO:0046982	protein heterodimerization activity	SNX1	IPI	UniProtKB:O60749	Human	PMID:11102511
Molecular Function	GO:0042803	protein homodimerization activity	SNX1	IPI	UniProtKB:Q13596	Human	PMID:11102511
Molecular Function	GO:1990459	transferrin receptor binding	SNX1	IDA		Human	PMID:9819414
Cellular Component	GO:0005737	cytoplasm	SNX1	IDA		Human	PMID:11279102
Cellular Component	GO:0005829	cytosol	Snx1	IDA		Rat	PMID:11110793|RGD:68866
Cellular Component	GO:0043197	dendritic spine	Snx1	IDA		Mouse	MGI:MGI:5562465|PMID:24261326
Cellular Component	GO:0005769	early endosome	Snx1	IDA		Mouse	PMID:19549681
Cellular Component	GO:0005769	early endosome	Snx1	IDA		Rat	PMID:11110793|RGD:68866
Cellular Component	GO:0031901	early endosome membrane	SNX1	IDA		Human	PMID:15498486
Cellular Component	GO:0005768	endosome	SNX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005768	endosome	Snx1	IDA		Mouse	PMID:15078902
Cellular Component	GO:0010008	endosome membrane	SNX1	IDA		Human	PMID:15673616
Cellular Component	GO:0010008	endosome membrane	SNX1	IDA		Human	PMID:22431521
Cellular Component	GO:0098999	extrinsic component of postsynaptic endosome membrane	Snx1	IDA		Mouse	PMID:24261326
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	SNX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005764	lysosome	SNX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	SNX1	IDA		Human	PMID:9819414
Cellular Component	GO:0016020	membrane	Snx1	IDA		Mouse	MGI:MGI:5582186|PMID:9819414
Cellular Component	GO:0016020	membrane	Snx1	IDA		Rat	PMID:11110793|RGD:68866
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Snx1	IDA		Mouse	PMID:19549681
Cellular Component	GO:0014069	postsynaptic density	Snx1	IDA		Mouse	MGI:MGI:5562465|PMID:24261326
Cellular Component	GO:0099092	postsynaptic density, intracellular component	Snx1	IDA		Mouse	PMID:24261326
Cellular Component	GO:0099092	postsynaptic density, intracellular component	Snx1	IEP		Mouse	PMID:24261326
Cellular Component	GO:0098793	presynapse	Snx1	IDA		Mouse	MGI:MGI:5562465|PMID:24261326
Cellular Component	GO:0032991	protein-containing complex	SNX1	IDA		Human	PMID:9819414
Cellular Component	GO:0030904	retromer complex	SNX1	IDA		Human	PMID:19619496
Cellular Component	GO:0030905	retromer, tubulation complex	SNX1	IPI	UniProtKB:O60749	Human	PMID:11102511
Cellular Component	GO:0031982	vesicle	SNX1	IDA		Human	PMID:25468996
Biological Process	GO:0034498	early endosome to Golgi transport	SNX1	IMP		Human	PMID:15498486
Biological Process	GO:0016197	endosomal transport	Snx1	IEP		Rat	PMID:11110793|RGD:68866
Biological Process	GO:0006886	intracellular protein transport	SNX1	IMP		Human	PMID:15498486
Biological Process	GO:0072673	lamellipodium morphogenesis	SNX1	IDA		Human	PMID:20604901
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	Snx1	IDA		Mouse	PMID:15239668
Biological Process	GO:0031175	neuron projection development	Snx1	IDA		Mouse	MGI:MGI:5562465|PMID:24261326
Biological Process	GO:0045732	positive regulation of protein catabolic process	Snx1	IMP		Rat	PMID:11110793|RGD:68866
Biological Process	GO:0031623	receptor internalization	SNX1	IMP		Human	PMID:20070609
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	SNX1	IMP		Human	PMID:18088323

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern