Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SNX2
  • Mouse genes Snx2
  • Rat genes Snx2
  • Zfish genes snx2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Snx2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	SNX2	HDA		Human	PMID:25468996
Molecular Function	GO:0005154	epidermal growth factor receptor binding	SNX2	IDA		Human	PMID:9819414
Molecular Function	GO:0042802	identical protein binding	SNX2	IPI	UniProtKB:O60749	Human	PMID:9819414
Molecular Function	GO:0005158	insulin receptor binding	SNX2	IDA		Human	PMID:9819414
Molecular Function	GO:1990460	leptin receptor binding	SNX2	IDA		Human	PMID:9819414
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q13596	Human	PMID:11102511
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:P36897	Human	PMID:11278302
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:O00238	Human	PMID:11279102
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:P36896	Human	PMID:11279102
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:P37173	Human	PMID:11279102
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q13705	Human	PMID:11279102
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q9UNH7	Human	PMID:11279102
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q96RU3	Human	PMID:11438682
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q96RU3	Human	PMID:14596906
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q9UNH7	Human	PMID:19619496
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q9Y5X3	Human	PMID:19619496
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q9UNH7	Human	PMID:19935774
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q9UNH7	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q13596	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q86XE0	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:O60664	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:O95070	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q15041	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q7L2Z9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q86XE0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q8WW34-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q96T60	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q9H2K0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q9UNH7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:P50570-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q16637	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q8TB36	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:O95219	Human	PMID:9819414
Molecular Function	GO:0005515	protein binding	SNX2	IPI	UniProtKB:Q13596	Human	PMID:9819414
Molecular Function	GO:0046982	protein heterodimerization activity	SNX2	IPI	UniProtKB:Q13596	Human	PMID:11102511
Molecular Function	GO:0042803	protein homodimerization activity	SNX2	IPI	UniProtKB:O60749	Human	PMID:11102511
Molecular Function	GO:1990459	transferrin receptor binding	SNX2	IDA		Human	PMID:9819414
Cellular Component	GO:0005737	cytoplasm	SNX2	IDA		Human	PMID:11279102
Cellular Component	GO:0005768	endosome	SNX2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0010008	endosome membrane	SNX2	IDA		Human	PMID:15673616
Cellular Component	GO:0005764	lysosome	SNX2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	SNX2	IDA		Human	PMID:9819414
Cellular Component	GO:0016020	membrane	Snx2	IDA		Mouse	MGI:MGI:5582186|PMID:9819414
Cellular Component	GO:0032991	protein-containing complex	SNX2	IDA		Human	PMID:9819414
Cellular Component	GO:0030904	retromer complex	SNX2	IDA		Human	PMID:11102511
Cellular Component	GO:0030904	retromer complex	SNX2	IDA		Human	PMID:19619496
Cellular Component	GO:0030905	retromer, tubulation complex	SNX2	IPI	UniProtKB:Q13596	Human	PMID:11102511
Biological Process	GO:0072673	lamellipodium morphogenesis	SNX2	IDA		Human	PMID:20604901
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	SNX2	IMP		Human	PMID:20138391

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern