Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SNX27
  • Mouse genes Snx27
  • Rat genes Snx27
  • Zfish genes snx27a,snx27b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Snx27

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	Snx27	IPI	RGD:61862	Rat	PMID:25071192|RGD:13508620
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	Snx27	IPI	RGD:621531	Rat	PMID:25071192|RGD:13508620
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	SNX27	IDA		Human	PMID:21300787
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	Snx27	IDA		Rat	PMID:17828261|RGD:8554502
Molecular Function	GO:0005515	protein binding	SNX27	IPI	UniProtKB:P23508	Human	PMID:19555689
Molecular Function	GO:0005515	protein binding	SNX27	IPI	UniProtKB:P07550	Human	PMID:20733053
Molecular Function	GO:0005515	protein binding	SNX27	IPI	UniProtKB:O15439	Human	PMID:22411990
Molecular Function	GO:0005515	protein binding	SNX27	IPI	UniProtKB:P11166	Human	PMID:23563491
Molecular Function	GO:0005515	protein binding	SNX27	IPI	UniProtKB:Q04656	Human	PMID:23563491
Molecular Function	GO:0005515	protein binding	SNX27	IPI	UniProtKB:Q96QK1	Human	PMID:27385586
Molecular Function	GO:0005515	protein binding	SNX27	IPI	UniProtKB:Q9BYF1	Human	PMID:33436498
Molecular Function	GO:0005515	protein binding	SNX27	IPI	UniProtKB:P0DTC2	Human	PMID:34504087
Molecular Function	GO:0005515	protein binding	SNX27	IPI	UniProtKB:Q9BYF1	Human	PMID:34835087
Molecular Function	GO:0005515	protein binding	SNX27	IPI	UniProtKB:P0DTC2	Human	PMID:34909756
Molecular Function	GO:0005515	protein binding	Snx27	IPI	PR:Q01098	Mouse	PMID:21300787
Molecular Function	GO:0005515	protein binding	Snx27	IPI	UniProtKB:P48550	Rat	PMID:17828261|RGD:8554502
Molecular Function	GO:0005515	protein binding	Snx27	IPI	UniProtKB:Q63511	Rat	PMID:17828261|RGD:8554502
Molecular Function	GO:0005515	protein binding	Snx27	IPI	RGD:621440	Rat	PMID:21422294|RGD:8554349
Molecular Function	GO:0005515	protein binding	Snx27	IPI	UniProtKB:Q63511	Rat	PMID:21422294|RGD:8554349
Cellular Component	GO:0005829	cytosol	SNX27	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Snx27	IDA		Rat	PMID:25071192|RGD:13508620
Cellular Component	GO:0005769	early endosome	SNX27	IDA		Human	PMID:20733053
Cellular Component	GO:0005769	early endosome	SNX27	IDA		Human	PMID:21300787
Cellular Component	GO:0005769	early endosome	Snx27	IDA		Rat	PMID:17828261|RGD:8554502
Cellular Component	GO:0005769	early endosome	Snx27	IDA		Rat	PMID:21422294|RGD:8554349
Cellular Component	GO:0005768	endosome	Snx27	IDA		Mouse	PMID:23382219
Cellular Component	GO:0098978	glutamatergic synapse	Snx27	IMP		Mouse	PMID:23524343
Cellular Component	GO:0098978	glutamatergic synapse	Snx27	IDA		Mouse	PMID:23524343
Cellular Component	GO:0098978	glutamatergic synapse	Snx27	IEP		Mouse	PMID:23524343
Cellular Component	GO:0001772	immunological synapse	SNX27	IDA		Human	PMID:17644068
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	SNX27	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Snx27	IDA		Rat	PMID:25071192|RGD:13508620
Cellular Component	GO:0014069	postsynaptic density	Snx27	IDA		Rat	PMID:25071192|RGD:13508620
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Snx27	IMP		Mouse	PMID:23524343
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Snx27	IDA		Mouse	PMID:23524343
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Snx27	IEP		Mouse	PMID:23524343
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Snx27	IEP		Rat	PMID:16076023|RGD:13508621
Biological Process	GO:0032456	endocytic recycling	SNX27	IMP		Human	PMID:20733053
Biological Process	GO:0032456	endocytic recycling	SNX27	IMP		Human	PMID:21602791
Biological Process	GO:0032456	endocytic recycling	SNX27	IMP		Human	PMID:23563491
Biological Process	GO:0016197	endosomal transport	SNX27	IMP		Human	PMID:21300787
Biological Process	GO:0016197	endosomal transport	Snx27	IMP	MGI:MGI:4949192	Mouse	PMID:21300787
Biological Process	GO:0016197	endosomal transport	Snx27	IMP		Rat	PMID:17828261|RGD:8554502
Biological Process	GO:0099638	endosome to plasma membrane protein transport	Snx27	IMP		Rat	PMID:25136126|RGD:13508597
Biological Process	GO:0061951	establishment of protein localization to plasma membrane	Snx27	IMP		Rat	PMID:25071192|RGD:13508620
Biological Process	GO:0006886	intracellular protein transport	SNX27	IMP		Human	PMID:20733053
Biological Process	GO:0006886	intracellular protein transport	SNX27	IMP		Human	PMID:21300787
Biological Process	GO:0006886	intracellular protein transport	SNX27	IMP		Human	PMID:21602791
Biological Process	GO:0006886	intracellular protein transport	SNX27	IMP		Human	PMID:23563491
Biological Process	GO:0006886	intracellular protein transport	Snx27	IMP		Rat	PMID:17828261|RGD:8554502
Biological Process	GO:1903609	negative regulation of inward rectifier potassium channel activity	Snx27	IDA		Rat	PMID:21422294|RGD:8554349
Biological Process	GO:1904719	positive regulation of AMPA glutamate receptor clustering	Snx27	IMP		Rat	PMID:25071192|RGD:13508620
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Snx27	IEP		Mouse	PMID:23524343
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Snx27	IDA		Mouse	PMID:23524343
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Snx27	IMP		Mouse	PMID:23524343
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Snx27	IDA		Mouse	PMID:21300787
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Snx27	IMP		Mouse	PMID:21300787
Biological Process	GO:1904313	response to methamphetamine hydrochloride	Snx27	IEP		Rat	PMID:12740601|RGD:633301

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern