Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SNX5
  • Mouse genes Snx5
  • Rat genes Snx5
  • Zfish genes snx5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Snx5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	SNX5	HDA		Human	PMID:25468996
Molecular Function	GO:0031748	D1 dopamine receptor binding	Snx5	IDA		Rat	PMID:23195037|RGD:13508622
Molecular Function	GO:0034452	dynactin binding	SNX5	IDA		Human	PMID:19619496
Molecular Function	GO:0035091	phosphatidylinositol binding	SNX5	IDA		Human	PMID:15561769
Molecular Function	GO:0035091	phosphatidylinositol binding	Snx5	IDA		Rat	PMID:19553671|RGD:8554826
Molecular Function	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	Snx5	IDA		Rat	PMID:16487940|RGD:13508623
Molecular Function	GO:0070273	phosphatidylinositol-4-phosphate binding	Snx5	IDA		Rat	PMID:16487940|RGD:13508623
Molecular Function	GO:0010314	phosphatidylinositol-5-phosphate binding	Snx5	IDA		Rat	PMID:16487940|RGD:13508623
Molecular Function	GO:0005515	protein binding	SNX5	IPI	UniProtKB:O60749	Human	PMID:19619496
Molecular Function	GO:0005515	protein binding	SNX5	IPI	UniProtKB:O75436	Human	PMID:19619496
Molecular Function	GO:0005515	protein binding	SNX5	IPI	UniProtKB:Q13596	Human	PMID:19619496
Molecular Function	GO:0005515	protein binding	SNX5	IPI	UniProtKB:Q14203	Human	PMID:19619496
Molecular Function	GO:0005515	protein binding	SNX5	IPI	UniProtKB:Q96QK1	Human	PMID:19619496
Molecular Function	GO:0005515	protein binding	SNX5	IPI	UniProtKB:Q9UBQ0	Human	PMID:19619496
Molecular Function	GO:0005515	protein binding	SNX5	IPI	UniProtKB:Q13596	Human	PMID:23085988
Molecular Function	GO:0005515	protein binding	SNX5	IPI	UniProtKB:Q92624	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SNX5	IPI	UniProtKB:Q86VI4	Human	PMID:25588945
Molecular Function	GO:0005515	protein binding	SNX5	IPI	UniProtKB:Q13596	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Snx5	IPI	UniProtKB:P0DJI4	Mouse	MGI:MGI:6414674|PMID:26118995
Molecular Function	GO:0005515	protein binding	Snx5	IPI	RGD:68962	Rat	PMID:16487940|RGD:13508623
Molecular Function	GO:0005515	protein binding	snx5	IPI	UniProtKB:Q80SY4	Zfish	PMID:16857196
Cellular Component	GO:0005903	brush border	Snx5	IDA		Rat	PMID:23195037|RGD:13508622
Cellular Component	GO:0005737	cytoplasm	Snx5	IDA		Rat	PMID:23195037|RGD:13508622
Cellular Component	GO:0098559	cytoplasmic side of early endosome membrane	SNX5	IDA		Human	PMID:15561769
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	SNX5	IDA		Human	PMID:15561769
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	SNX5	IDA		Human	PMID:18854019
Cellular Component	GO:0005829	cytosol	SNX5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Snx5	IDA		Rat	PMID:16487940|RGD:13508623
Cellular Component	GO:0005769	early endosome	snx5	IDA		Zfish	PMID:16857196
Cellular Component	GO:0005768	endosome	Snx5	IDA		Rat	PMID:16487940|RGD:13508623
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	SNX5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070685	macropinocytic cup	SNX5	IDA		Human	PMID:18854019
Cellular Component	GO:0048471	perinuclear region of cytoplasm	SNX5	IDA		Human	PMID:25825816
Cellular Component	GO:0005886	plasma membrane	Snx5	IDA		Rat	PMID:16487940|RGD:13508623
Cellular Component	GO:0030904	retromer complex	SNX5	IDA		Human	PMID:19619496
Cellular Component	GO:0097422	tubular endosome	SNX5	IDA		Human	PMID:19619496
Biological Process	GO:0048514	blood vessel morphogenesis	snx5	IMP	ZFIN:ZDB-MRPHLNO-061117-3	Zfish	PMID:16857196
Biological Process	GO:0007174	epidermal growth factor catabolic process	Snx5	IDA		Rat	PMID:16487940|RGD:13508623
Biological Process	GO:0042063	gliogenesis	snx5	IMP	ZFIN:ZDB-MRPHLNO-060601-5,ZFIN:ZDB-MRPHLNO-061117-3	Zfish	PMID:25645681
Biological Process	GO:0030097	hemopoiesis	snx5	IMP	ZFIN:ZDB-MRPHLNO-061117-3	Zfish	PMID:16857196
Biological Process	GO:0045776	negative regulation of blood pressure	Snx5	IMP		Rat	PMID:23195037|RGD:13508622
Biological Process	GO:0007219	Notch signaling pathway	snx5	IMP	ZFIN:ZDB-MRPHLNO-060601-5,ZFIN:ZDB-MRPHLNO-061117-3	Zfish	PMID:25645681
Biological Process	GO:0006907	pinocytosis	SNX5	IDA		Human	PMID:18854019
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	SNX5	IMP		Human	PMID:25825816
Biological Process	GO:0046628	positive regulation of insulin receptor signaling pathway	SNX5	IMP		Human	PMID:25825816
Biological Process	GO:0035815	positive regulation of renal sodium excretion	Snx5	IMP		Rat	PMID:23195037|RGD:13508622
Biological Process	GO:0060041	retina development in camera-type eye	snx5	IMP	ZFIN:ZDB-MRPHLNO-060601-5,ZFIN:ZDB-MRPHLNO-061117-3	Zfish	PMID:25645681
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	SNX5	IMP		Human	PMID:17148574

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern