Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SNX6
  • Mouse genes Snx6
  • Rat genes Snx6
  • Zfish genes snx6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Snx6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0034452	dynactin binding	SNX6	IDA		Human	PMID:19619496
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:P36897	Human	PMID:11278302
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:O60749	Human	PMID:11279102
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:O95219	Human	PMID:11279102
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:P00533	Human	PMID:11279102
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:P06213	Human	PMID:11279102
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:P37173	Human	PMID:11279102
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:P48357	Human	PMID:11279102
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:Q13596	Human	PMID:11279102
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:Q13705	Human	PMID:11279102
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:Q9UNH7	Human	PMID:11279102
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:O60749	Human	PMID:19619496
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:O75436	Human	PMID:19619496
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:Q13596	Human	PMID:19619496
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:Q14203	Human	PMID:19619496
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:Q96QK1	Human	PMID:19619496
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:Q9UBQ0	Human	PMID:19619496
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:O60749	Human	PMID:19935774
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:Q13596	Human	PMID:19935774
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:Q14203	Human	PMID:19935774
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:P56817	Human	PMID:20354142
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:Q9HCU9	Human	PMID:20830743
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:O60749	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:Q13596	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:Q13596	Human	PMID:23524952
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:Q14203	Human	PMID:23524952
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:P0DJI4	Human	PMID:26118995
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:Q13596	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:O60749	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:Q13596	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:Q8IYF3-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SNX6	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0042803	protein homodimerization activity	SNX6	IPI	UniProtKB:Q9UNH7	Human	PMID:11279102
Molecular Function	GO:0034713	type I transforming growth factor beta receptor binding	Snx6	IPI	UniProtKB:Q64729	Mouse	MGI:MGI:5545984|PMID:21266196
Cellular Component	GO:0005737	cytoplasm	SNX6	IDA		Human	PMID:11279102
Cellular Component	GO:0005737	cytoplasm	SNX6	IDA		Human	PMID:20830743
Cellular Component	GO:0031901	early endosome membrane	SNX6	IDA		Human	PMID:19935774
Cellular Component	GO:0005768	endosome	SNX6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005768	endosome	Snx6	IDA		Rat	PMID:18523162|RGD:13513208
Cellular Component	GO:0098978	glutamatergic synapse	Snx6	IDA		Mouse	PMID:28134614
Cellular Component	GO:0098978	glutamatergic synapse	Snx6	IMP		Mouse	PMID:28134614
Cellular Component	GO:0005764	lysosome	SNX6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030904	retromer complex	SNX6	IDA		Human	PMID:19619496
Cellular Component	GO:0097422	tubular endosome	SNX6	IDA		Human	PMID:19619496
Biological Process	GO:1904646	cellular response to amyloid-beta	SNX6	IGI	RNAcentral:URS00004E0808_9606	Human	PMID:27541017
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	Snx6	IDA		Rat	PMID:18523162|RGD:13513208
Biological Process	GO:0006886	intracellular protein transport	SNX6	IMP		Human	PMID:19935774
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	SNX6	IDA		Human	PMID:11279102
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	SNX6	IDA		Human	PMID:20830743
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	SNX6	IGI	RNAcentral:URS00004E0808_9606	Human	PMID:27541017
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	SNX6	IDA		Human	PMID:11279102
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Snx6	IDA		Mouse	PMID:28134614
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Snx6	IMP		Mouse	PMID:28134614
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	SNX6	IMP		Human	PMID:19935774

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern