Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CCDC169-SOHLH2,SOHLH2
  • Mouse genes Sohlh2
  • Rat genes Sohlh2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sohlh2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Sohlh2	IDA		Mouse	MGI:MGI:5492024|PMID:22328502
Molecular Function	GO:0042802	identical protein binding	Sohlh2	IPI	PR:Q9D489	Mouse	PMID:22056784
Molecular Function	GO:0005515	protein binding	Sohlh2	IPI	PR:Q6IUP1	Mouse	PMID:22056784
Molecular Function	GO:0046982	protein heterodimerization activity	Sohlh2	IDA		Mouse	MGI:MGI:5302159|PMID:22056784
Molecular Function	GO:0042803	protein homodimerization activity	Sohlh2	IDA		Mouse	MGI:MGI:5302159|PMID:22056784
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Sohlh2	IDA		Mouse	MGI:MGI:5492024|PMID:22328502
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	SOHLH2	IDA		Human	PMID:28473536
Biological Process	GO:0030154	cell differentiation	Sohlh2	IDA		Mouse	MGI:MGI:5302159|PMID:22056784
Biological Process	GO:0009994	oocyte differentiation	Sohlh2	IDA		Mouse	MGI:MGI:5913174|PMID:28504655
Biological Process	GO:0009994	oocyte differentiation	Sohlh2	IMP	MGI:MGI:3839324	Mouse	PMID:18753606
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sohlh2	IDA		Mouse	MGI:MGI:5492024|PMID:22328502
Biological Process	GO:0001545	primary ovarian follicle growth	Sohlh2	IMP	MGI:MGI:3839324	Mouse	PMID:18753606
Biological Process	GO:0010468	regulation of gene expression	Sohlh2	IMP	MGI:MGI:3839324	Mouse	PMID:18753606
Biological Process	GO:0007283	spermatogenesis	Sohlh2	IDA		Mouse	MGI:MGI:5302159|PMID:22056784

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern