Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SORBS2
  • Mouse genes Sorbs2
  • Rat genes Sorbs2
  • Zfish genes sorbs2a,sorbs2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sorbs2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SORBS2	IPI	UniProtKB:P63104	Human	PMID:15161933
Molecular Function	GO:0005515	protein binding	SORBS2	IPI	UniProtKB:Q8WX93	Human	PMID:16125169
Molecular Function	GO:0005515	protein binding	SORBS2	IPI	UniProtKB:Q13177	Human	PMID:16374509
Molecular Function	GO:0005515	protein binding	SORBS2	IPI	UniProtKB:Q9WMX2:PRO_0000037551	Human	PMID:18985028
Molecular Function	GO:0005515	protein binding	SORBS2	IPI	UniProtKB:P63104	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SORBS2	IPI	UniProtKB:A5D8V6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SORBS2	IPI	UniProtKB:O43281	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SORBS2	IPI	UniProtKB:O43639	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SORBS2	IPI	UniProtKB:P42768	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SORBS2	IPI	UniProtKB:Q8N5M1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SORBS2	IPI	UniProtKB:Q9H788-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SORBS2	IPI	UniProtKB:V9HW98	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Sorbs2	IPI	PR:P47941	Mouse	PMID:26527617
Molecular Function	GO:0019904	protein domain specific binding	Sorbs2	IPI	PR:P10126	Mouse	PMID:21689717
Molecular Function	GO:0003723	RNA binding	SORBS2	HDA		Human	PMID:22658674
Cellular Component	GO:0030425	dendrite	Sorbs2	IDA		Rat	PMID:10521485|RGD:631969
Cellular Component	GO:0043025	neuronal cell body	Sorbs2	IDA		Rat	PMID:10521485|RGD:631969
Cellular Component	GO:0005886	plasma membrane	Sorbs2	IDA		Mouse	PMID:21689717
Cellular Component	GO:0014069	postsynaptic density	Sorbs2	IDA		Rat	PMID:10521485|RGD:631969
Cellular Component	GO:0045202	synapse	Sorbs2	IDA		Mouse	PMID:26527617
Biological Process	GO:0095500	acetylcholine receptor signaling pathway	Sorbs2	IGI	MGI:MGI:700014	Mouse	PMID:26527617
Biological Process	GO:0095500	acetylcholine receptor signaling pathway	Sorbs2	IGI	MGI:MGI:104686	Mouse	PMID:26527617
Biological Process	GO:0061049	cell growth involved in cardiac muscle cell development	Sorbs2	IGI	RNAcentral:URS000015930E_10116	Rat	PMID:24743145|RGD:10054083
Biological Process	GO:0007219	Notch signaling pathway	Sorbs2	IDA		Mouse	PMID:23117660
Biological Process	GO:0002027	regulation of heart rate	sorbs2b	IGI	ZFIN:ZDB-MRPHLNO-210409-2,ZFIN:ZDB-MRPHLNO-210409-3	Zfish	PMID:32808564
Biological Process	GO:0002027	regulation of heart rate	sorbs2a	IGI	ZFIN:ZDB-MRPHLNO-210409-2,ZFIN:ZDB-MRPHLNO-210409-3	Zfish	PMID:32808564
Biological Process	GO:1904393	regulation of skeletal muscle acetylcholine-gated channel clustering	Sorbs2	IGI	MGI:MGI:104686	Mouse	PMID:26527617
Biological Process	GO:1904393	regulation of skeletal muscle acetylcholine-gated channel clustering	Sorbs2	IGI	MGI:MGI:700014	Mouse	PMID:26527617

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern